메뉴 건너뛰기




Volumn 93, Issue 3, 1996, Pages 688-693

High incidence of anti-FVIII antibodies against non-coagulant epitopes in haemophilia A patients: A possible role for the half-life of transfused FVIII

Author keywords

Anti FVIII antibodies; FVIII half life; Haemophilia A; Immunoassay

Indexed keywords

BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 ANTIBODY; BLOOD CLOTTING FACTOR 8 CONCENTRATE;

EID: 0029887497     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.d01-1705.x     Document Type: Article
Times cited : (71)

References (23)
  • 2
  • 3
    • 0027196024 scopus 로고
    • Sequence of the murine factor VIII cDNA
    • Elder, B., Lakich, D. & Gitscheir, J. (1993) Sequence of the murine factor VIII cDNA. Genomics, 16, 374-379.
    • (1993) Genomics , vol.16 , pp. 374-379
    • Elder, B.1    Lakich, D.2    Gitscheir, J.3
  • 4
    • 0025402779 scopus 로고
    • A murine monoclonal anti-factor VIII inhibitory antibody and two human factor VIII inhibitors bind to different areas within a twenty aminoacid segment of the acidic region of factor VIII heavy chain
    • Foster, P.A., Fulcher, C.A., Houghten, R.A., Mahoney, S., de Graaf, S. & Zimmerman, T.S. (1990) A murine monoclonal anti-factor VIII inhibitory antibody and two human factor VIII inhibitors bind to different areas within a twenty aminoacid segment of the acidic region of factor VIII heavy chain. Blood Coagulation and Fibrinolysis, 1, 9-15.
    • (1990) Blood Coagulation and Fibrinolysis , vol.1 , pp. 9-15
    • Foster, P.A.1    Fulcher, C.A.2    Houghten, R.A.3    Mahoney, S.4    De Graaf, S.5    Zimmerman, T.S.6
  • 5
    • 0027488655 scopus 로고
    • Anti-FVIII antibodies of hemophiliac patients are frequently directed towards nonfunctional determinants and do not exhibit isotypic restriction
    • Gilles, J.G.G., Arnout, J., Vermylen, J. & Saint-Remy, J.M.R. (1993) Anti-FVIII antibodies of hemophiliac patients are frequently directed towards nonfunctional determinants and do not exhibit isotypic restriction. Blood, 82, 2452-2461.
    • (1993) Blood , vol.82 , pp. 2452-2461
    • Gilles, J.G.G.1    Arnout, J.2    Vermylen, J.3    Saint-Remy, J.M.R.4
  • 6
    • 0027938488 scopus 로고
    • Healthy subjects produce both anti-factor VIII and specific anti-idiotypic antibodies
    • Gilles, J.G.G. & Saint-Remy, J.M.R. (1994) Healthy subjects produce both anti-factor VIII and specific anti-idiotypic antibodies. Journal of Clinical Investigation, 84, 1496-1505.
    • (1994) Journal of Clinical Investigation , vol.84 , pp. 1496-1505
    • Gilles, J.G.G.1    Saint-Remy, J.M.R.2
  • 7
    • 0029059149 scopus 로고
    • Why do so many haemophilia A patients develop an inhibitor?
    • Hoyer, L.W. (1995). Why do so many haemophilia A patients develop an inhibitor? British Journal of Haematology, 90, 498-501.
    • (1995) British Journal of Haematology , vol.90 , pp. 498-501
    • Hoyer, L.W.1
  • 9
    • 0027520025 scopus 로고
    • Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A
    • Lakich, D., Kazazian, H., Antonarakis, S. & Gitschier, J. (1993) Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A. Nature Genetics, 5, 236-240.
    • (1993) Nature Genetics , vol.5 , pp. 236-240
    • Lakich, D.1    Kazazian, H.2    Antonarakis, S.3    Gitschier, J.4
  • 10
    • 0024504004 scopus 로고
    • Identification of a FVIII epitope recognised by a human hemophilic inhibitor
    • Lubahan, B.C., Ware, J., Stafford, D.W. & Reisner, H.M. (1989) Identification of a FVIII epitope recognised by a human hemophilic inhibitor. Blood, 73, 497-499.
    • (1989) Blood , vol.73 , pp. 497-499
    • Lubahan, B.C.1    Ware, J.2    Stafford, D.W.3    Reisner, H.M.4
  • 12
    • 0026730499 scopus 로고
    • Factor VIII gene explains all cases of haemophilia A
    • Naylor, J.A., Green, P.M. & Rizza, C.R. (1992) Factor VIII gene explains all cases of haemophilia A. Lancet, 340, 1066-1067.
    • (1992) Lancet , vol.340 , pp. 1066-1067
    • Naylor, J.A.1    Green, P.M.2    Rizza, C.R.3
  • 13
    • 0025068910 scopus 로고
    • Noncoagulation inhibitory factor VIII antibodies in hemophilia A patients
    • Nilsson, I.M., Berntorp, E., Zettervall, O. & Dahlback, B. (1990) Noncoagulation inhibitory factor VIII antibodies in hemophilia A patients. Blood, 75, 378-383.
    • (1990) Blood , vol.75 , pp. 378-383
    • Nilsson, I.M.1    Berntorp, E.2    Zettervall, O.3    Dahlback, B.4
  • 14
    • 0028125949 scopus 로고
    • Quantitation of factor VIII antibodies by an enzyme-linked immunoassay method
    • Regnault, V. & Stoltz, J.F. (1994) Quantitation of factor VIII antibodies by an enzyme-linked immunoassay method. Blood, 83, 1155-1156.
    • (1994) Blood , vol.83 , pp. 1155-1156
    • Regnault, V.1    Stoltz, J.F.2
  • 15
    • 0027211041 scopus 로고
    • Polymorphisms in pocket of major histocompatibility complex class I molecules influence peptide preference
    • Rohren, E.M., Pease, L.R., Ploegh, H. & Schumacher, T.N. (1993) Polymorphisms in pocket of major histocompatibility complex class I molecules influence peptide preference. Journal of Experimental Medicine, 177, 1713-1721.
    • (1993) Journal of Experimental Medicine , vol.177 , pp. 1713-1721
    • Rohren, E.M.1    Pease, L.R.2    Ploegh, H.3    Schumacher, T.N.4
  • 16
    • 0025343156 scopus 로고
    • Immunological characterisation of factor VIII inhibitors by a sensitive micro-ELISA method
    • Sanches-Cuenca, J.M., Carmona, E., Villanueva, M.J. & Aznar, J.A. (1990) Immunological characterisation of factor VIII inhibitors by a sensitive micro-ELISA method. Thrombosis Research, 57, 897-908.
    • (1990) Thrombosis Research , vol.57 , pp. 897-908
    • Sanches-Cuenca, J.M.1    Carmona, E.2    Villanueva, M.J.3    Aznar, J.A.4
  • 18
    • 0024451521 scopus 로고
    • Localization of epitopes fro human factor VIII antibodies by immunoblotting and antibody neutralization
    • Scandella, D., Mattingly, M., de Graaf, S. & Fulcher, C.A. (1989) Localization of epitopes fro human factor VIII antibodies by immunoblotting and antibody neutralization. Blood, 74, 1618-1626.
    • (1989) Blood , vol.74 , pp. 1618-1626
    • Scandella, D.1    Mattingly, M.2    De Graaf, S.3    Fulcher, C.A.4
  • 20
    • 0027496218 scopus 로고
    • Incidence of inhibitors in haemophiliacs: A review of the literature
    • Sharrer, I. & Neutzling, O. (1993) Incidence of inhibitors in haemophiliacs: a review of the literature. Blood Coagulation and Fibrinolysis, 4, 752-758.
    • (1993) Blood Coagulation and Fibrinolysis , vol.4 , pp. 752-758
    • Sharrer, I.1    Neutzling, O.2
  • 21
    • 0028233134 scopus 로고
    • Inversions in the factor VIII gene in Spanish hemophilia A patients
    • Tizzano, E.F. & Domenech, M. (1994) Inversions in the factor VIII gene in Spanish hemophilia A patients. Blood, 83, 3826.
    • (1994) Blood , vol.83 , pp. 3826
    • Tizzano, E.F.1    Domenech, M.2
  • 23
    • 0027050152 scopus 로고
    • Epitope mapping of human factor VIII inhibitor antibodies by site-directed mutagenesis of factor VIII polypeptide
    • Ware, J., MacDonald, M.J., Lo, M., de Graaf, S. & Fulcher, C.A. (1992) Epitope mapping of human factor VIII inhibitor antibodies by site-directed mutagenesis of factor VIII polypeptide. Blood Coagulation and Fibrinolysis, 3, 703-716.
    • (1992) Blood Coagulation and Fibrinolysis , vol.3 , pp. 703-716
    • Ware, J.1    MacDonald, M.J.2    Lo, M.3    De Graaf, S.4    Fulcher, C.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.