Attitude of potential users in Sicily towards preimplantation genetic diagnosis for β-thalassaemia and aneuploidies

Human Reproduction

Volumn 13, Issue 7, 1998, Pages 1936-1944

  Chamayou, S ^a,b   Guglielmino, A ^a   Giambona, A ^a,c   Siciliano, S ^a,c   Di Stefano, G ^a,c   Scibilia, G ^a   Humeau, C ^a,b   Maggio, A ^a,c   Di Leo, S ^a  

^a Unit di Med Della Ripro   (Italy)

^b UNIV MONTPELLIER   (France)

^c VILLA SOFIA CERVELLO HOSPITAL   (Italy)

Author keywords

Aneuploidies; Preimplantation; Sicily; User; thalassaemia

Indexed keywords

ADULT; ANAMNESIS; ANEUPLOIDY; ARTICLE; BETA THALASSEMIA; FEMALE; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT ATTITUDE; PREIMPLANTATION EMBRYO; PRENATAL DIAGNOSIS; QUESTIONNAIRE; THERAPEUTIC ABORTION;

EID: 0031825880     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/13.7.1936     Document Type: Article

References (24)

1. Brambati, B., Oldrini, A., Ferrazzie, E. and Lanzani, A. (1987) Chorionic villus sampling: an analysis of the obstetrics experience of 1000 cases. Prenat. Diagn., 7, 157-169.
2. Caronia, F., Siciliano, S., Di Marzo, R. et al. (1989) Lo screening delle emoglobinopathie finalizzato alla diagnosi prenatale. Haematologia, 74 (Suppl. 5), 223-230.
3. Edwards, R.G. (1995) Clinical approaches to increasing uterine receptivity during human implantation. Hum. Reprod., 10 (Suppl. 2), 60-66.
4. Fiddler, M. and Pergament, E. (1996) Medically-assisted procreation: a maturing technology or a premature fear? Response to Testart and Sèle. Hum. Reprod., 11, 708-709.
5. Giambona, A. (1995) The great heterogeneity of thalassaemia molecular defects in Sicily. Hum. Genet., 95, 526-530.
6. Handyside, A.H. (1996) Common-sense as applied to eugenics: response to Testart and Sèle. Hum. Reprod., 11, 707.
7. Handyside, A.H., Kontogianni, E.H., Hardy, K. and Winston, R.M.L. (1990) Pregnancies from biopsied human preimplantation embryos sexed by Y- specific DNA amplification. Nature, 344, 768-770.
8. Harper, J.C. (1996) Preimplantation diagnosis of inherited disease by embryo biopsy: an update of the world figures. J. Assist. Reprod. Genet., 13, 90-95.
9. Kazazian, H.H., Dowling, C.E., Boehm, C.D. et al. (1990) Gene defects in β-thalassaemia in their prenatal diagnosis. In Bank,A. (ed.) Sixth Cooley's Anemia Symposium, 1-14. Annals of N.Y. Academy of Sciences.
10. Kenyon, S.L., Hackett, G.A. and Campell, S. (1988) Termination of pregnancy diagnosis of fetal malformation: the need for improved follow up services. Clin. Obstet. Gynecol., 31, 97-100.
11. Miedzybrodzka, Z., Templeton, A., Dean, J. et al. (1993) Preimplantation diagnosis or chorionic villus biopsy? Women's attitudes and preferences. Hum. Reprod., 8, 2192-2196.
12. Mullis, K.B. and Faloona, F. (1987) Specific synthesis of DNA in vitro via polymerase-catalyzed chain reaction. Methods Enzymol., 155, 335-350.
13. Palermo, G., Joris, H., Devroey, P. and Van Steirteghem, A.C. (1992) Pregnancies after intracytoplasmic injection of single spermatozoa into an oocyte. Lancet, 340, 17-18.
14. Palomba, M.L., Monni, G., Lai, R. et al. (1994) Psychological implications and acceptability of preimplantation diagnosis. Hum. Reprod., 9, 360-362.
15. Pergament, E. (1991) Preimplantation diagnosis: a patient perspective. Prenat. Diagn., 11, 493-500.
16. Ray, P.P. and Handyside, A.H. (1996) Increasing the denaturation temperature during the first cycles of amplification reduces allele dropout from single cells for preimplantation genetic diagnosis. Hum. Reprod., 2, 213-218.
17. Rodgers, G.P. and Rachmilewitz, E.A. (1995) Novel treatment options in the severe β-gene disorders. Br. J. Haematol., 91, 263-268.
18. Saiki, R.K., Scharf, S., Faloona, F. et al. (1985) Enzymatic amplification of β-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science, 230, 1350-1354.
19. Snowdon, C. and Green, J. (1997) Preimplantation diagnosis and other reproductive options: attitudes of male and female carriers of recessive disorders. Hum. Reprod., 12, 341-350.
20. Tarin, J.J. and Handyside, A.H. (1993) Embryo biopsy strategies for preimplantation diagnosis. Fertil. Steril., 59, 943-952.
21. Testart, J. and Sèle. B. (1995) Towards an efficient medical eugenics: is the desirable always the feasible? Hum. Reprod., 10, 3086-3090.
22. Thein, S.L, (1993) β-thalassaemia. Baillière's Clinical Haematology, 6, 151- 175.
23. Van Steirteghem, A.C., Nagy, Z., Joris, H. et al. (1993) High fertilization and implantation rates after intracytoplasmic sperm injection. Hum. Reprod., 8, 1061-1066.
24. Weatherall, D.J. and Clegg, J.B. (1981) The Thalassaemia Syndromes, 3rd edn, Blackwell, Oxford.