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Volumn 5, Issue 4, 1998, Pages 289-297

Wortmannin enhances activation of CPP32 (Caspase-3) induced by TNF or anti-Fas

Author keywords

Apoptosis; Caspase 3 (CPP32); Fas; PI 3K; TNF; Wortmannin

Indexed keywords

CASPASE 3; CYSTEINE PROTEINASE; DNA FRAGMENT; FAS ANTIGEN; MYOSIN LIGHT CHAIN KINASE; PHOSPHOTRANSFERASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 0031821739     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400355     Document Type: Article
Times cited : (39)

References (45)
  • 1
    • 0027432424 scopus 로고
    • Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-triphosphate in neutrophil responses
    • Arcaro M and Wymann MP (1993) Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-triphosphate in neutrophil responses. Biochem. J. 296: 297-301
    • (1993) Biochem. J. , vol.296 , pp. 297-301
    • Arcaro, M.1    Wymann, M.P.2
  • 3
    • 0028841897 scopus 로고
    • Phosphotyrosine residues in the nerve-growth-factor receptor(Trk-A).Their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells
    • Baxter RN, Cohen P, Ullrich A, Downes CP and Doza YN (1995) Phosphotyrosine residues in the nerve-growth-factor receptor(Trk-A).Their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells. Eur. J. Biochem. 234: 84-91
    • (1995) Eur. J. Biochem. , vol.234 , pp. 84-91
    • Baxter, R.N.1    Cohen, P.2    Ullrich, A.3    Downes, C.P.4    Doza, Y.N.5
  • 4
    • 0028360309 scopus 로고
    • Induction of a common pathway of apoptosis by staurosporine Exp
    • Bertrand R, Solary E, O'Conner P, Kohn KW and Pommier Y (1994) Induction of a common pathway of apoptosis by staurosporine Exp. Cell Res. 211: 314-321
    • (1994) Cell Res. , vol.211 , pp. 314-321
    • Bertrand, R.1    Solary, E.2    O'Conner, P.3    Kohn, K.W.4    Pommier, Y.5
  • 5
    • 0028985261 scopus 로고
    • Self-association of the death domains of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects
    • Boldin MP, Mett IL, Varfolomeev EE, Chumakov I, Shemer-Avni Y, Camonis JH and Wallach D (1995) Self-association of the death domains of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects. J. Biol. Chem. 270: 387-391
    • (1995) J. Biol. Chem. , vol.270 , pp. 387-391
    • Boldin, M.P.1    Mett, I.L.2    Varfolomeev, E.E.3    Chumakov, I.4    Shemer-Avni, Y.5    Camonis, J.H.6    Wallach, D.7
  • 6
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
    • Boldin MP, Goncharov TM, Goltsev YV and Wallach D (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85: 803-815
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 9
    • 0029026548 scopus 로고
    • FADD, a Novel death domain-containing protein interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan AM, O'Rourke K, Tewari M and Dixit VM (1995) FADD, a Novel death domain-containing protein interacts with the death domain of Fas and initiates apoptosis. Cell 81: 505-512
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3    Dixit, V.M.4
  • 10
    • 0029912189 scopus 로고    scopus 로고
    • Molecular ordering of the cell death pathway, bcl-2 and bcl-xL function upstream of the CED-3-like apoptotic proteases
    • Chinnaiyan AM, Orth K, O'Rourke K, Duan H, Poiner GG and Dixit VM (1996a) Molecular ordering of the cell death pathway, bcl-2 and bcl-xL function upstream of the CED-3-like apoptotic proteases. J. Biol. Chem. 271: 4573-4576
    • (1996) J. Biol. Chem. , vol.271 , pp. 4573-4576
    • Chinnaiyan, A.M.1    Orth, K.2    O'Rourke, K.3    Duan, H.4    Poiner, G.G.5    Dixit, V.M.6
  • 12
    • 0031034997 scopus 로고    scopus 로고
    • Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death
    • Chinnaiyan AM, O'Rourke K, Lane BR and Dixit VM (1997) Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death. Science 275: 1122-1126
    • (1997) Science , vol.275 , pp. 1122-1126
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Lane, B.R.3    Dixit, V.M.4
  • 13
    • 0029066697 scopus 로고
    • Contenders in FasL/TNF death signaling
    • Cleveland JL and Ihle JM (1995) Contenders in FasL/TNF death signaling Cell 81: 479-482
    • (1995) Cell , vol.81 , pp. 479-482
    • Cleveland, J.L.1    Ihle, J.M.2
  • 16
    • 0029978182 scopus 로고    scopus 로고
    • Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
    • Enan M, Talanian RV, Wong WW and Nagata S (1996) Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380: 723-726
    • (1996) Nature , vol.380 , pp. 723-726
    • Enan, M.1    Talanian, R.V.2    Wong, W.W.3    Nagata, S.4
  • 17
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1b-converting enzyme
    • Fernandes-Alnemn T, Litwack G and Alnemri ES (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1b-converting enzyme. J. Biol. Chem. 269: 30761-30764
    • (1994) J. Biol. Chem. , vol.269 , pp. 30761-30764
    • Fernandes-Alnemn, T.1    Litwack, G.2    Alnemri, E.S.3
  • 19
    • 0031039024 scopus 로고    scopus 로고
    • Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
    • Franke T, Kaplan DR, Cantley LC and Tokert A (1997) Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science 275: 665-668
    • (1997) Science , vol.275 , pp. 665-668
    • Franke, T.1    Kaplan, D.R.2    Cantley, L.C.3    Tokert, A.4
  • 20
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NF-kB activation
    • Hsu H, Xiong J and Goeddel DV (1995) The TNF receptor 1-associated protein TRADD signals cell death and NF-kB activation Cell 81: 495-504
    • (1995) Cell , vol.81 , pp. 495-504
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 21
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • Hsu H, Shu H-B, Pan M-G and Goeddel DV (1996) TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84: 299-308
    • (1996) Cell , vol.84 , pp. 299-308
    • Hsu, H.1    Shu, H.-B.2    Pan, M.-G.3    Goeddel, D.V.4
  • 22
    • 0027281373 scopus 로고
    • A novel protein domain required for apoptosis. mutational analysis of human Fas antigen
    • Itoh N and Nagata S (1993) A novel protein domain required for apoptosis. mutational analysis of human Fas antigen. J. Biol Chem 268 10932-10937
    • (1993) J. Biol Chem , vol.268 , pp. 10932-10937
    • Itoh, N.1    Nagata, S.2
  • 23
    • 0028891473 scopus 로고
    • Activation and possible involvement of calpain, a calcium-activated cysteine protease, in down-regulation of apoptosis of human monoblast U937 cells
    • Kikuchi H and Imajoh-Ohmi S (1995) Activation and possible involvement of calpain, a calcium-activated cysteine protease, in down-regulation of apoptosis of human monoblast U937 cells. Cell Death Differ 2: 195-199
    • (1995) Cell Death Differ , vol.2 , pp. 195-199
    • Kikuchi, H.1    Imajoh-Ohmi, S.2
  • 24
    • 0028837491 scopus 로고
    • Suppression of apoptotic death in hematopoietic cells by signaling through the IL-3/GM-CSF receptors
    • Kinoshita T, Yokota T Arai K and Miyajima A (1995) Suppression of apoptotic death in hematopoietic cells by signaling through the IL-3/GM-CSF receptors. EMBO J. 14: 266-275
    • (1995) EMBO J. , vol.14 , pp. 266-275
    • Kinoshita, T.1    Yokota, T.2    Arai, K.3    Miyajima, A.4
  • 25
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1b-converting enzyme, a mammalian homolog of the C elegans cell death gene ced-3
    • Miura M, Zhu H, Rotello R, Hartwieg EA and Yuan J (1993) Induction of apoptosis in fibroblasts by IL-1b-converting enzyme, a mammalian homolog of the C elegans cell death gene ced-3 Cell 75 653-660
    • (1993) Cell , vol.75 , pp. 653-660
    • Miura, M.1    Zhu, H.2    Rotello, R.3    Hartwieg, E.A.4    Yuan, J.5
  • 26
    • 0031584807 scopus 로고    scopus 로고
    • Specific expression of CPP32 in sensory neurons of mouse embryos and activation of CPP32 in the apoptosis induced by a withdrawal of NGF
    • Mukasa T, Urase K, Kimura I, Momoi YM and Momoi T (1997a) Specific expression of CPP32 in sensory neurons of mouse embryos and activation of CPP32 in the apoptosis induced by a withdrawal of NGF. Biochem. Biophys. Res. Commun 231. 770-774
    • (1997) Biochem. Biophys. Res. Commun , vol.231 , pp. 770-774
    • Mukasa, T.1    Urase, K.2    Kimura, I.3    Momoi, Y.M.4    Momoi, T.5
  • 27
    • 0031555891 scopus 로고    scopus 로고
    • Wortmannin enhances CPP32-like activity during neuronal differentiation of P19 embryonal carcinoma cells induced by retinoic acid
    • Mukasa T, Kohroku Y, Tsukahara T, Kimura I, Momoi YM and Momoi T (1997b) Wortmannin enhances CPP32-like activity during neuronal differentiation of P19 embryonal carcinoma cells induced by retinoic acid Biochem. Biophys. Res. Commun 232. 192-197
    • (1997) Biochem. Biophys. Res. Commun , vol.232 , pp. 192-197
    • Mukasa, T.1    Kohroku, Y.2    Tsukahara, T.3    Kimura, I.4    Momoi, Y.M.5    Momoi, T.6
  • 31
    • 0028124189 scopus 로고
    • Essential rote of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes
    • Okada T, Kawano Y, Sakakibara T, Hazeki O and Ui M (1994) Essential rote of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. J. Biol. Chem. 269. 3568-3573
    • (1994) J. Biol. Chem. , vol.269 , pp. 3568-3573
    • Okada, T.1    Kawano, Y.2    Sakakibara, T.3    Hazeki, O.4    Ui, M.5
  • 32
    • 0027512102 scopus 로고
    • A safe and rapid method for analyzing apoptosis-induced fragmentation of DNA extracted from tissues or cultured cells
    • Pringent P, Blanpied C, Aten J and Hirsch F (1993) A safe and rapid method for analyzing apoptosis-induced fragmentation of DNA extracted from tissues or cultured cells. J Immunol. Methods 160: 139-140
    • (1993) J Immunol. Methods , vol.160 , pp. 139-140
    • Pringent, P.1    Blanpied, C.2    Aten, J.3    Hirsch, F.4
  • 33
    • 0027365768 scopus 로고
    • Spatial resolution of fodrin proteolysis in postischemic brain
    • Saido TC, Tsuchiya T, Suzuki K and Kawashima S (1993) Spatial resolution of fodrin proteolysis in postischemic brain. Biol Chem. 268 25239-25243
    • (1993) Biol Chem. , vol.268 , pp. 25239-25243
    • Saido, T.C.1    Tsuchiya, T.2    Suzuki, K.3    Kawashima, S.4
  • 35
    • 0029054725 scopus 로고
    • RIP: A novel protein containing a death domain that interact with Fas/APO-1 (CD95) in yeast and causes cell death
    • Stanger BZ, Leder P, Lee T-H, Kim E and Seed B (1995) RIP: A novel protein containing a death domain that interact with Fas/APO-1 (CD95) in yeast and causes cell death Cell 81: 513-523
    • (1995) Cell , vol.81 , pp. 513-523
    • Stanger, B.Z.1    Leder, P.2    Lee, T.-H.3    Kim, E.4    Seed, B.5
  • 36
    • 0027275490 scopus 로고
    • A novel domain within the 55kd TNF receptor signals cell death
    • Tartaglia LA, Ayres TM, Wong GH and Goeddel DV (1993) A novel domain within the 55kd TNF receptor signals cell death. Cell 74: 845-853
    • (1993) Cell , vol.74 , pp. 845-853
    • Tartaglia, L.A.1    Ayres, T.M.2    Wong, G.H.3    Goeddel, D.V.4
  • 37
    • 0028873964 scopus 로고
    • Fas- and TNF-induced apoptosis is inhibited by the poxvirus crm A gene product
    • Tewari M and Dixit VM (1995) Fas- and TNF-induced apoptosis is inhibited by the poxvirus crm A gene product. J. Biol. Chem. 270: 3255-3260
    • (1995) J. Biol. Chem. , vol.270 , pp. 3255-3260
    • Tewari, M.1    Dixit, V.M.2
  • 38
    • 0028990125 scopus 로고
    • Yama/CPP32b, amammalian homolog of CED-3. is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-Ribose) polymerase
    • Tewari M, Quan LT, O'Rourke K, Desnoyers S, Zeng Z, Beidler DR, Poirier GG, Savesen GS and Dixit VM (1995) Yama/CPP32b, amammalian homolog of CED-3. is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-Ribose) polymerase. Cell 81: 801-809
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Savesen, G.S.8    Dixit, V.M.9
  • 40
    • 0027254106 scopus 로고
    • Relationship between apoptosis and the cell cycle in lymphocytes: Roles of protein kinase C, tyrosine phosphorylation, and AP1
    • Walker PR, Kwast-Welfeld J, Gourdeau H, Leblanc J, Neugebauer W and Sikorska M (1993) Relationship between apoptosis and the cell cycle in lymphocytes: roles of protein kinase C, tyrosine phosphorylation, and AP1. Exp. Cell Res. 207: 142-151
    • (1993) Exp. Cell Res. , vol.207 , pp. 142-151
    • Walker, P.R.1    Kwast-Welfeld, J.2    Gourdeau, H.3    Leblanc, J.4    Neugebauer, W.5    Sikorska, M.6
  • 41
    • 0345498292 scopus 로고    scopus 로고
    • Bcl-2 targets the protein kinase Raf-1 to mitochondria
    • Wang H-G, Rapp UR and Reed JC (1996) Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell 87: 629-638
    • (1996) Cell , vol.87 , pp. 629-638
    • Wang, H.-G.1    Rapp, U.R.2    Reed, J.C.3
  • 42
    • 0031020227 scopus 로고    scopus 로고
    • Interaction and regulation of subcellular localization of CED-4 by CED-9
    • Wu D, Wallen HD and Nunez G (1997) Interaction and regulation of subcellular localization of CED-4 by CED-9 Science 275: 1126-1128
    • (1997) Science , vol.275 , pp. 1126-1128
    • Wu, D.1    Wallen, H.D.2    Nunez, G.3
  • 43
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
    • Yao R and Cooper GM (1995) Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 267: 2003-2006
    • (1995) Science , vol.267 , pp. 2003-2006
    • Yao, R.1    Cooper, G.M.2
  • 44
    • 0027525104 scopus 로고
    • The C.elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1b-converting enzyme
    • Yuan J-Y, Shaham S, Ledoux S, Ellis HM and Horvitz HR (1993) The C.elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1b-converting enzyme. Cell 75: 641-652
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.-Y.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5
  • 45
    • 0030584088 scopus 로고    scopus 로고
    • Senne phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not Bcl-xL
    • Zha J, Harada H, Yang E, Jockel J, Korsmeyer SJ (1996) Senne phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not Bcl-xL. Cell 87: 619-628
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5


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