Effect of soy-derived isoflavonoids on the induced growth of MCF-7 cells by estrogenic environmental chemicals

Nutrition and Cancer

Volumn 30, Issue 3, 1998, Pages 232-239

  Verma, Surendra P ^a   Goldin, Barry R ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1,1 TRICHLORO 2 (2 CHLOROPHENYL) 2 (4 CHLOROPHENYL)ETHANE; BIOCHANIN A; DAIDZEIN; ENVIRONMENTAL CHEMICAL; EQUOL; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; FORMONONETIN; GENISTEIN; ISOFLAVONOID; NONYLPHENOL;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CANCER PREVENTION; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DIET; HUMAN; HUMAN CELL; SOYBEAN;

GLYCINE MAX; MINK CELL FOCUS-FORMING VIRUS;

EID: 0031810666     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1080/01635589809514669     Document Type: Article

References (45)

1. Estrogens in the environment. III. Global health implications. Environ Health Perspect 103 Suppl 7, 1995.
2. Soto, AM, Justicia, H, Wray, JW, and Sonnenschein, C: p-Nonylphenol: an estrogenic xenobiotic released from modified polystyrene. Environ Health Perspect 92, 167-173, 1991.
3. Shelby, MD, Newbold, RR, Tully, DB, Chae, K, and Davis, VL: Assessing environmental chemicals for estrogenicity using a combination of in vitro and in vivo assays. Environ Health Perspect 104, 1296-1300, 1996.
4. White, R, Jobling, S, Hoare, SA, Sumpter, JP, and Parker, MG: Environmentally persistent alkylphenolic compounds are estrogenic. Endocrinology 185, 175-182, 1994.
5. Lech, JJ, Lewis, SK, and Ren, L: In vivo estrogenic activity of nonylphenol in rainbow trout. Fundam Appl Toxicol 30, 229-232, 1996.
6. Jobling, S, Reynolds, T, White, R, Parker, MG, and Sumpter, JP: A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic. Environ Health Perspect 103, 582-587, 1995.
7. Purdom, CE, Hardiman, PA, Bye, VJ, Eno, NC, Tyler, CR, et al.: Estrogenic effects of effluents from sewage treatment works. Chem Ecol 8, 275-285, 1994.
8. Arnold, SF, Robinson, MK, Notides, AC, Guillette, LJ, Jr, and McLachlan, JA: A yeast estrogen screen for examining the relative exposure of cells to natural and xenoestrogens. Environ Health Perspect 104, 544-548, 1996.
9. Chen, CW, Hurd, C, Vorojeikina, DP, Arnold, SF, and Notides, AC: Transcriptional activation of the human estrogen receptor by DDT and metabolites in yeast and MCF-7 cells. Biochem Pharmacol 53, 1161-1172, 1997.
10. Fry, DM: Reproductive effects in birds exposed to pesticides and industrial chemicals. Environ Health Perspect 103 Suppl 7, 165-171, 1995.
11. Guillette, LJ, Jr, Gross, TS, Gross, DA, Rooney, AA, and Percival, HF: Gonadal steroidogenesis in vitro from juvenile alligators obtained from contaminated or control lakes. Environ Health Perspect 103 Suppl 4, 31-36, 1995.
12. Colborn, T, Dumanoski, D, and Myers, JP: Our Stolen Future: Are We Threatening Our Fertility, Intelligence, and Survival? A Scientific Detective Story. New York: Penguin, 1996.
13. Falck, F, Ricci, AJ, Wolff, MS, Godbold, J, and Deckers, P: Pesticides and polychlorinated biphenyl residues in human breast lipids and their relation to breast cancer. Arch Environ Health 47, 143-146, 1992.
14. Wolff, MS, Toniolo, PG, Lee, EW, Rivera, M, and Dubin, N: Blood levels of organochlorine residues and risk of breast cancer. JNCI 85, 648-652, 1993.
15. Dewailly, E, Dodin, S, Verreault, R, Ayotte, P, Sauve, L, et al.: High organochlorine body burden in women with estrogen receptor positive breast cancer. JNCI 86, 232-234, 1994.
16. Hunter, DJ, Hankinson, SE, Laden, F, Colditz, GA, Manson, JE, et al.: Plasma organochlorine levels and the risk of breast cancer. N Engl J Med 337, 1253-1258, 1997.
17. Adlercreutz, H: Lignans and phytoestrogens. Front Gastrointest Res 14, 165-176, 1988.
18. Verma, SP, Salamone, E, and Goldin, BR: Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides. Biochem Biophys Res Commun 233, 692-696, 1997.
19. Sasaki, K, Ishizaka, S, Suzuki, T, Takeda, M, and Uchiyama, M: Accumulation levels of organochlorine pesticides in human adipose tissue and blood. Bull Environ Contam Toxicol 46, 662-669, 1991.
20. van der Ven, K, van der Ven, H, Thibold, A, Bauer, O, Kaisi, M, et al.: Chlorinated hydrocarbon content of fetal and maternal body tissues and fluids in full term pregnant women: a comparison of Germany versus Tanzania. Hum Reprod 7, 95-100, 1992.
21. Toppari, J, Larsen, JC, Christiansen, P, Giwercman, A, Grandjean, P, et al.: Male reproductive health and environmental xenoestrogens. Environ Health Perspect 104, 741-803, 1996.
22. Bigsby, RM, Caperell-Grant, A, and Madhukar, BV: Xenobiotics released from fat during fasting produce estrogenic effects in ovariectomized mice. Cancer Res 57, 865-869, 1997.
23. Huang, Z, Hankinson, SE, Colditz, GA, Stampfer, MJ, Hunter, DJ, et al.: Dual effects of weight and weight gain on breast cancer risk. JAMA 279, 1407-1411, 1997.
24. Adlercreutz, H: Phytoestrogens: epidemiology and a possible role in cancer protection. Environ Health Perspect 103 Suppl 7, 103-112, 1996.
25. Fotsis, T, Pepper, MS, Aktas, E, Breit, S, Rasku, S, et al.: Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis. Cancer Res 57, 2916-2921, 1997.
26. Fotsis, T, Pepper, MS, Aldercreutz, A, Hase, T, Montesano, R, et al.: Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis. J Nutr 125 Suppl, 790S-797S, 1995.
27. Adlercreutz, H, Hamalainen, E, Gorbach, SL, Goldin, BR, Woods, MN, et al.: Diet and plasma androgens in postmenopausal vegetarian and omnivorous women and postmenopausal women with breast cancer. Am J Clin Nutr 49, 433-442, 1989.
28. Adlercreutz, H, Goldin, BR, Gorbach, SL, Hockerstedt, KAV, Watanabe, S, et al.: Soybean phytoestrogen intake and cancer risk. J Nutr 125, 7575-7705, 1995.
29. Soto, AM, Sonnenschein, C, Chung, KL, Fernandez, MF, Olea, N, et al.: The E-screen assay as a tool to identify estrogens: an update on estrogenic environmental pollutants. Environ Health Perspect 103 Suppl 7, 113-122, 1995.
30. Balabhadrapathruni, S, Thomas. T, and Thomas, TJ: Estrogenic and anti-estrogenic actions of genistein in human breast cancer cell growth mediated through the polyamine pathway (abstr). Proc Am Assoc Cancer Res 207, 1391, 1997.
31. So, FV, Guthrie, N, Chambers, AF, and Carroll, KK: Inhibition of proliferation of estrogen-positive MCF-7 human breast cancer cells by flavonoids in the presence and absence of excess estrogen. Cancer Lett 112, 127-133, 1997.
32. Peterson, G, and Barnes, S: Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene. Biochem Biophys Res Commun 179, 661-667, 1991.
33. Pagliacci, MC, Spinozzi, F, Migliorati, G, Fumi, G, Smacchia, M, et al.: Genistein inhibits tumor cell growth in vitro but enhances mitochondrial reduction of tetrazolium salts: a further pitfall in the use of the MTT assay for evaluating cell growth and survival. Eur J Cancer 29A, 1573-1577, 1993.
34. Karr, SC, Lampe, JW, Hutchins, AM, and Slavin, J: Urinary isoflavonoid excretion in humans is dose dependent at low to moderate levels of soy-protein consumption. Am J Clin Nutr 66, 46-51, 1997.
35. Clarke, R, van den Berg, HW, and Murphy, RF: Reduction of the membrane fluidity of human breast cancer cells by tamoxifen and 17-β estradiol. JNCI 82, 1702-1705, 1990.
36. Wiseman, H: Tamoxifen: new membrane-mediated mechanisms of action and therapeutic advances. Trends Pharmacol Sci 15, 83-89, 1994.
37. i - a novel antiestrogenic mechanism in human breast cancer cells (abstr). Proc Am Assoc Cancer Res 37, 225, 1996.
38. Trump, BF, Jain, PT, Phelps, PC, Chang, SH, and Berezesky, IK: Calcium measurements in the assessment of in vitro toxicity. In In Vitro Toxicology Mechanism and New Technology, AM Goldberg (ed). New York: Liebert, 1993, vol 9, p 175-184. (Alternative Methods Toxicol Ser)
39. 2+, phorbol esters and ATP. J Biol Chem 260, 15718-15722, 1985.
40. 2+] in human breast cancer cells. Anticancer Res 17, 1167-1174, 1997.
41. Sasaki, K, Ishizaka, S, Suzuki, T, Takeda, M, and Uchiyama, M: Accumulation levels of organochlorine pesticides in human adipose tissue and blood. Bull Environ Contam Toxicol 46, 662-669, 1991.
42. Costantinou, A, Kiguchi, K, and Huberman, E: Induction of differentiation and DNA strand breakage in human HL60 and K-562 leukemia cells by genistein. Cancer Res 50, 2618-2624, 1990.
43. Lei, W, Mayotte, J, and Levitt, ML: Genistein inhibits epidermal growth factor-mediated MAP kinase activity and induces squamous differentiation and apoptosis in human non-small cell lung cancer cells (abstr). Proc Am Assoc Cancer Res 38, 499, 1997.
44. Dean, NM, Kanemitsu, M, and Boynton, AL: Effect of the tyrosine-kinase inhibitor genistein on DNA synthesis and phospholipid-derived second messenger generation in mouse 1OT2/2 fibroblasts and rat liver T51B cells. Biochem Biophys Res Commun 165, 795-801, 1989.
45. Marlkovitz, J, Linassier, C, Fosse, P, Couprie, J, Pierre, J, et al.: Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II. Cancer Res 49, 5111-5117, 1989.