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Volumn 285, Issue 2, 1998, Pages 428-437

Identification and characterization of human cytochrome P450 isoforms interacting with pimozide

Author keywords

[No Author keywords available]

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; CYTOCHROME P450 ISOENZYME; DEXTRORPHAN; DRUG METABOLITE; FURAFYLLINE; KETOCONAZOLE; LEVALLORPHAN; PIMOZIDE; RECOMBINANT ENZYME; TROLEANDOMYCIN;

EID: 0031808548     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (71)

References (54)
  • 1
    • 0027193806 scopus 로고
    • Possible interaction between, fluoxetine and pimozide causing sinus bradycardia
    • Ahmed I, Dagincourt PG, Miller LG and Shader RI (1993) Possible interaction between, fluoxetine and pimozide causing sinus bradycardia. Can J Psychiatry 38:62-83.
    • (1993) Can J Psychiatry , vol.38 , pp. 62-83
    • Ahmed, I.1    Dagincourt, P.G.2    Miller, L.G.3    Shader, R.I.4
  • 2
    • 0030468097 scopus 로고    scopus 로고
    • Cellular and ionic mechanisms underlying erythromycin-induced long QT intervals and torsades de pointes
    • Antzelevitch C, Zhuo-Quian S, Zi-Qing Z and Gan-Xin Y (1996) Cellular and ionic mechanisms underlying erythromycin-induced long QT intervals and torsades de pointes. J Am Coll Cardiol 28:1836-1848.
    • (1996) J Am Coll Cardiol , vol.28 , pp. 1836-1848
    • Antzelevitch, C.1    Zhuo-Quian, S.2    Zi-Qing, Z.3    Gan-Xin, Y.4
  • 5
    • 0015511260 scopus 로고
    • Assorbimento, metabolismo ed excrezione della pimozide nella uomo
    • Baro F, Brugnums J and Heykants J (1972) Assorbimento, metabolismo ed excrezione della pimozide nella uomo. Clin Ter 63:239-249.
    • (1972) Clin ter , vol.63 , pp. 239-249
    • Baro, F.1    Brugnums, J.2    Heykants, J.3
  • 6
    • 0029028932 scopus 로고
    • Geographical/inter-racial differences in polymorphic drug oxidation: Current state of knowledge of cytochromes P450 2D6 and 2C19
    • Bertilsson L (1995) Geographical/inter-racial differences in polymorphic drug oxidation: Current state of knowledge of cytochromes P450 2D6 and 2C19. Clin Pharmacokinet 29:192-209.
    • (1995) Clin Pharmacokinet , vol.29 , pp. 192-209
    • Bertilsson, L.1
  • 7
    • 0030935086 scopus 로고    scopus 로고
    • Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
    • Bertz RJ and Granneman GR (1997) Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin Pharmacokinet 32:210-258.
    • (1997) Clin Pharmacokinet , vol.32 , pp. 210-258
    • Bertz, R.J.1    Granneman, G.R.2
  • 8
    • 0030430033 scopus 로고    scopus 로고
    • Cytochrome P450 isoform inhibitors as a tool for investigation of metabolic reactions catalyzed by human liver microBomes
    • Bourriè M, Meunier V, Berger Y and Fabre G (1996) Cytochrome P450 isoform inhibitors as a tool for investigation of metabolic reactions catalyzed by human liver microBomes. J Pharmacol Exp Ther 277:321-332.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 321-332
    • Bourriè, M.1    Meunier, V.2    Berger, Y.3    Fabre, G.4
  • 9
    • 0024359553 scopus 로고
    • Effect of quinidine on the dextromethorphan O-deniethylase activity of microaomal fractions from human liver
    • Broly F, Libersa C, Lhermitte M, Bechtel P and Dupuis B (1989) Effect of quinidine on the dextromethorphan O-deniethylase activity of microaomal fractions from human liver. Br J Clin Pharmacol 28:29-36.
    • (1989) Br J Clin Pharmacol , vol.28 , pp. 29-36
    • Broly, F.1    Libersa, C.2    Lhermitte, M.3    Bechtel, P.4    Dupuis, B.5
  • 10
    • 0029145903 scopus 로고
    • Drug interactions and the cytochrome P450 system. The role of cytochrome P450 1A2
    • Brosen K (1995) Drug interactions and the cytochrome P450 system. The role of cytochrome P450 1A2. Clin Pharmacokinet 29: suppl. 1, 20-25.
    • (1995) Clin Pharmacokinet , vol.29 , Issue.SUPPL. 1 , pp. 20-25
    • Brosen, K.1
  • 12
    • 0026561862 scopus 로고
    • Pharmacotherapy of Tourette's syndrome and associated disorders
    • Cohen DJ, Riddle MA and Leckman JF (1992) Pharmacotherapy of Tourette's syndrome and associated disorders. Pediatr Psychopharmacol 15:109-128.
    • (1992) Pediatr Psychopharmacol , vol.15 , pp. 109-128
    • Cohen, D.J.1    Riddle, M.A.2    Leckman, J.F.3
  • 17
    • 0027440142 scopus 로고
    • Pharmacokinetic interaction with antimicrobial agents
    • Gillum JG, Israel DS and Polk RE (1993) pharmacokinetic interaction with antimicrobial agents. Clin Pharmacokinet 25:450-482.
    • (1993) Clin Pharmacokinet , vol.25 , pp. 450-482
    • Gillum, J.G.1    Israel, D.S.2    Polk, R.E.3
  • 18
    • 0027956791 scopus 로고
    • Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily
    • Gorski JC, Jones DR, Wrighton SA and Hall SD (1994) Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily, Biochem Pharmacol 48:173-182.
    • (1994) Biochem Pharmacol , vol.48 , pp. 173-182
    • Gorski, J.C.1    Jones, D.R.2    Wrighton, S.A.3    Hall, S.D.4
  • 19
    • 0026035519 scopus 로고
    • Role of human cytochrome P450IIE1 in the oxidation of many low molecular weight cancer suspects
    • Guengerich FP, Kim D-H and Iwasaki H (1991) Role of human cytochrome P450IIE1 in the oxidation of many low molecular weight cancer suspects. Chem Res Toxicol 4:168-179.
    • (1991) Chem Res Toxicol , vol.4 , pp. 168-179
    • Guengerich, F.P.1    Kim, D.-H.2    Iwasaki, H.3
  • 20
    • 0028812667 scopus 로고
    • An investigation of the interaction between halofantrine, CYP2D6 and CYP 3A4: Studies with human liver microsomes and heterologous enzyme expression systems
    • Halliday RC, Jones BC, Smith DA, Kitteringham NR and Park BK (1995) An investigation of the interaction between halofantrine, CYP2D6 and CYP 3A4: Studies with human liver microsomes and heterologous enzyme expression systems. Br J Clin Pharmacol 35:369-374.
    • (1995) Br J Clin Pharmacol , vol.35 , pp. 369-374
    • Halliday, R.C.1    Jones, B.C.2    Smith, D.A.3    Kitteringham, N.R.4    Park, B.K.5
  • 22
    • 0027957132 scopus 로고
    • Metabolism of taxol by human hepatic microsomes and liver slices: Participation of cytochrome P450 3A4 and an unknown P450 enzyme
    • Harris JW, Rahman A, Kim BR, Guengerich FP and Collins JM (1994) Metabolism of taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme. Cancer Res 54:4026-4035.
    • (1994) Cancer Res , vol.54 , pp. 4026-4035
    • Harris, J.W.1    Rahman, A.2    Kim, B.R.3    Guengerich, F.P.4    Collins, J.M.5
  • 23
    • 0029833258 scopus 로고    scopus 로고
    • Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin
    • Heyn HH, White RB and Stevens JC (1996) Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin. Drug Metab Dispos 24:948-954.
    • (1996) Drug Metab Dispos , vol.24 , pp. 948-954
    • Heyn, H.H.1    White, R.B.2    Stevens, J.C.3
  • 25
    • 0022390883 scopus 로고
    • In vitro inhibition studies of two isoenzymes of human liver cytochrome P-450: Mephenytoin p-hydroxylase and sparteine monooxygenase
    • Inaba T, Jurima M, Mahon WA and Kalow W (1985) In vitro inhibition studies of two isoenzymes of human liver cytochrome P-450: Mephenytoin p-hydroxylase and sparteine monooxygenase. Drug Metab Dispos 13:443-448.
    • (1985) Drug Metab Dispos , vol.13 , pp. 443-448
    • Inaba, T.1    Jurima, M.2    Mahon, W.A.3    Kalow, W.4
  • 26
    • 0030971321 scopus 로고    scopus 로고
    • Sensitive assay for pimozide in human plasma using high-performance liquid chromatography with fluorescence detection: Application to pharmacokinetic studies
    • Kerbuach T, Desta Z, Soukhova NV, Thacker D and Flockhart DA (1997) Sensitive assay for pimozide in human plasma using high-performance liquid chromatography with fluorescence detection: application to pharmacokinetic studies. J Chromatogr 694:163-168.
    • (1997) J Chromatogr , vol.694 , pp. 163-168
    • Kerbuach, T.1    Desta, Z.2    Soukhova, N.V.3    Thacker, D.4    Flockhart, D.A.5
  • 28
    • 0030811096 scopus 로고    scopus 로고
    • Evaluation of omeprazole and Lanaoprazole as inhibitors of cytochrome P450 isoforms
    • Ko J-W, Soukhova N, Thacker D, Chen P and Flockhart DA (1997) Evaluation of omeprazole and Lanaoprazole as inhibitors of cytochrome P450 isoforms. Drug Metab Dispos 26:853-862.
    • (1997) Drug Metab Dispos , vol.26 , pp. 853-862
    • Ko, J.-W.1    Soukhova, N.2    Thacker, D.3    Chen, P.4    Flockhart, D.A.5
  • 29
    • 0029065958 scopus 로고
    • Case report: Reversible QT prolongation with torsade de pointes in a patient with ptoozide intoxication
    • Krthenbühl S, Sauter B, Kupferschmidt H, Krause M, Wyss P and Meier PJ (1995) Case report: reversible QT prolongation with torsade de pointes in a patient with ptoozide intoxication. Am J Med Sci 309:315-316.
    • (1995) Am J Med Sci , vol.309 , pp. 315-316
    • Krthenbühl, S.1    Sauter, B.2    Kupferschmidt, H.3    Krause, M.4    Wyss, P.5    Meier, P.J.6
  • 30
    • 0027946851 scopus 로고
    • Genetic differences in drug disposition
    • May DG (1994) Genetic differences in drug disposition. J Clin Pharmacol 34:881-897.
    • (1994) J Clin Pharmacol , vol.34 , pp. 881-897
    • May, D.G.1
  • 31
    • 0021140149 scopus 로고
    • Within-individual vahation in steady state plasma levels of different neuroleptics and prolactin
    • McCreadie RG, Mackie M, Wiles DH, Jorgensen A, Hansen V and Menzies C (1984) Within-individual vahation in steady state plasma levels of different neuroleptics and prolactin. Br J Psychiatry 144:625-629.
    • (1984) Br J Psychiatry , vol.144 , pp. 625-629
    • McCreadie, R.G.1    Mackie, M.2    Wiles, D.H.3    Jorgensen, A.4    Hansen, V.5    Menzies, C.6
  • 32
    • 0028858960 scopus 로고
    • Cytochrome P450 inhibitors: Evaluation of ipecificities in the in vitro metabolism of therapeutic agents by human liver microsomes
    • Newton DJ, Wang RW and Lu AYH (1995) Cytochrome P450 inhibitors: Evaluation of ipecificities in the in vitro metabolism of therapeutic agents by human liver microsomes Drug Metab Dispos 23:154-158.
    • (1995) Drug Metab Dispos , vol.23 , pp. 154-158
    • Newton, D.J.1    Wang, R.W.2    Lu, A.Y.H.3
  • 33
    • 0029788377 scopus 로고    scopus 로고
    • Drug interaction with azithromycin and the macrolides: An overview
    • Nahata M (1996) Drug interaction with azithromycin and the macrolides: An overview. J Antimicrob Chemother 37: suppl. C,133-142.
    • (1996) J Antimicrob Chemother , vol.37 , Issue.SUPPL. C , pp. 133-142
    • Nahata, M.1
  • 34
    • 0025729597 scopus 로고
    • The role of pimozide in clinical psychiatry: A review
    • Opler LA and Feinberg SS (1991) The role of pimozide in clinical psychiatry: A review. J Clin Psychiatry 52:221-223.
    • (1991) J Clin Psychiatry , vol.52 , pp. 221-223
    • Opler, L.A.1    Feinberg, S.S.2
  • 36
    • 0018098415 scopus 로고
    • Effect of smoking on caffeine clearance
    • Parsons WD and Neims AH (1978) Effect of smoking on caffeine clearance. Clin Pharmacol Ther 24:40-45.
    • (1978) Clin Pharmacol Ther , vol.24 , pp. 40-45
    • Parsons, W.D.1    Neims, A.H.2
  • 38
    • 0017188036 scopus 로고
    • Pimozide: A review of its pharmacological properties and therapeutic uses in psychiatry
    • Pinder RM, Brogden RN, Sawyer PR, Speigt TM, Spencer R and Avery GS (1976) Pimozide: A review of its pharmacological properties and therapeutic uses in psychiatry. Drugs 12:1-40.
    • (1976) Drugs , vol.12 , pp. 1-40
    • Pinder, R.M.1    Brogden, R.N.2    Sawyer, P.R.3    Speigt, T.M.4    Spencer, R.5    Avery, G.S.6
  • 40
    • 0025014594 scopus 로고
    • Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily
    • Helling MV, Aoyama T, Gonzalez FJ and Meyer UA (1990) Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily. J Pharmacol Exp Ther 252:442-447
    • (1990) J Pharmacol Exp Ther , vol.252 , pp. 442-447
    • Helling, M.V.1    Aoyama, T.2    Gonzalez, F.J.3    Meyer, U.A.4
  • 43
    • 0030872372 scopus 로고    scopus 로고
    • Relative efficacy of haloperidol and pimozide in children and adolescents with Tourett's disorder
    • Sallee FR, Nesbitt L, Jackson C, Sine L and Sethuraman G (1997) Relative efficacy of haloperidol and pimozide in children and adolescents with Tourett's disorder. Am J Psychiatry 154:1057-1062.
    • (1997) Am J Psychiatry , vol.154 , pp. 1057-1062
    • Sallee, F.R.1    Nesbitt, L.2    Jackson, C.3    Sine, L.4    Sethuraman, G.5
  • 46
    • 0028237729 scopus 로고
    • Interindividual variation in human liver cytochrome P450 enzyme involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microaomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazaki H, Mimaru M, Inui Y and Guengerich FP (1994) Interindividual variation in human liver cytochrome P450 enzyme involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microaomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270:414-423.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimaru, M.3    Inui, Y.4    Guengerich, F.P.5
  • 47
    • 0014489860 scopus 로고
    • The metabolism and excretion of the neuroleptic pimozide by the Wistar rat
    • Soudijn W and Wijngaarden I (1969) The metabolism and excretion of the neuroleptic pimozide by the Wistar rat. Life Sci 8:291-295.
    • (1969) Life Sci , vol.8 , pp. 291-295
    • Soudijn, W.1    Wijngaarden, I.2
  • 49
    • 0027456656 scopus 로고
    • Clinical uses of pimozide
    • Tueth MJ and Cheong JA (1993) Clinical uses of pimozide. South Med J 86:344-349.
    • (1993) South Med J , vol.86 , pp. 344-349
    • Tueth, M.J.1    Cheong, J.A.2
  • 50
  • 51
    • 0029872402 scopus 로고    scopus 로고
    • Interaction of human liver cytochromes P450 in vitro with LY307640, a gastric proton pump inhibitor
    • VandenBranden M, Ring BJ, Binkley SN and Wrighton SA (1996) Interaction of human liver cytochromes P450 in vitro with LY307640, a gastric proton pump inhibitor. Pharmacogenetics 6:81-91.
    • (1996) Pharmacogenetics , vol.6 , pp. 81-91
    • VandenBranden, M.1    Ring, B.J.2    Binkley, S.N.3    Wrighton, S.A.4
  • 52
    • 0027474601 scopus 로고
    • Mechanism of cardiotoxicity of terfenadine
    • Woosley RL, Chen Y, Frieman J and Gillis RA (1993) Mechanism of cardiotoxicity of terfenadine. JAMA 269:403-409.
    • (1993) JAMA , vol.269 , pp. 403-409
    • Woosley, R.L.1    Chen, Y.2    Frieman, J.3    Gillis, R.A.4
  • 53
    • 0027445449 scopus 로고
    • Isolation and characterization of human liver cytochrome P450 2C19: Correlation between 2C19 and S-mephenytoin 4′-hydroxylation
    • Wrighton SA, Stevens JC, Becker GW and VandenBranden M (1993) Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4′-hydroxylation, Arch Biochem Biophys 306:240-245
    • (1993) Arch Biochem Biophys , vol.306 , pp. 240-245
    • Wrighton, S.A.1    Stevens, J.C.2    Becker, G.W.3    VandenBranden, M.4


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