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Volumn 18, Issue 6, 1998, Pages 415-421

The development of autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein is associated with an upregulation of both proinflammatory and immunoregulatory cytokines in the central nervous system

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLYCOPROTEIN; INTERLEUKIN 10; INTERLEUKIN 4; MYELIN PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031802920     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1998.18.415     Document Type: Article
Times cited : (31)

References (36)
  • 1
    • 0029888979 scopus 로고    scopus 로고
    • Two models for multiple sclerosis: Experimental allergic encephalomyelitis and Theiler's murine encephalomyelitis virus
    • TSUKADA, I., and FUJINAMI, R.S. (1996). Two models for multiple sclerosis: experimental allergic encephalomyelitis and Theiler's murine encephalomyelitis virus. J. Neuropathol. Exp. Neurol. 55, 673-686.
    • (1996) J. Neuropathol. Exp. Neurol. , vol.55 , pp. 673-686
    • Tsukada, I.1    Fujinami, R.S.2
  • 2
    • 0025856061 scopus 로고
    • Experimental autoimmune encephalomyelitis is exacerbated by IL-1α and suppressed by soluble IL-1 receptor
    • JACOBS, C.A., BAKER, P.E., ROUX, E.R., PICHA, K.S., TOIVOLA, B., WAUGH, S., and KENNEDY, M.K. (1991). Experimental autoimmune encephalomyelitis is exacerbated by IL-1α and suppressed by soluble IL-1 receptor. J. Immunol. 146, 2983-2989.
    • (1991) J. Immunol. , vol.146 , pp. 2983-2989
    • Jacobs, C.A.1    Baker, P.E.2    Roux, E.R.3    Picha, K.S.4    Toivola, B.5    Waugh, S.6    Kennedy, M.K.7
  • 3
    • 0026558531 scopus 로고
    • Effect of anti-interferon-γ and antiinterleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse
    • DUONG, T.T., ST. LOUIS, J., GILBERT, J.J., FINKELMAN, F.D., and STREJAN, G.H. (1992). Effect of anti-interferon-γ and antiinterleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse. J. Neuroimmunol. 36, 105-115.
    • (1992) J. Neuroimmunol. , vol.36 , pp. 105-115
    • Duong, T.T.1    St. Louis, J.2    Gilbert, J.J.3    Finkelman, F.D.4    Strejan, G.H.5
  • 4
    • 0029411144 scopus 로고
    • Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL-6 bioactivity in central nervous system and circulation
    • GIJBELS, K., BROCKE, S., ABRAMS, J.S., and STEINMAN, L. (1995). Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL-6 bioactivity in central nervous system and circulation. Mol. Med. 1, 795-805.
    • (1995) Mol. Med. , vol.1 , pp. 795-805
    • Gijbels, K.1    Brocke, S.2    Abrams, J.S.3    Steinman, L.4
  • 5
    • 0025000863 scopus 로고
    • An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis
    • RUDDLE, N.H., BERGMAN, C.M., MCGRATH, K.M., LINGENHELD, E.G., GRUNNET, M.L., PADULA, S.J., and CLARK, R.B. (1990). An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis. J. Exp. Med. 172, 1193-1200.
    • (1990) J. Exp. Med. , vol.172 , pp. 1193-1200
    • Ruddle, N.H.1    Bergman, C.M.2    Mcgrath, K.M.3    Lingenheld, E.G.4    Grunnet, M.L.5    Padula, S.J.6    Clark, R.B.7
  • 6
    • 0026094706 scopus 로고
    • Anti-tumor necrosis factor therapy abrogates autoimmune demyelination
    • SELMAJ, K., RAINE, C.S., and CROSS, A.H. (1991). Anti-tumor necrosis factor therapy abrogates autoimmune demyelination. Ann. Neurol. 30, 694-700.
    • (1991) Ann. Neurol. , vol.30 , pp. 694-700
    • Selmaj, K.1    Raine, C.S.2    Cross, A.H.3
  • 8
    • 0028245010 scopus 로고
    • Interleukin-10 prevents experimental allergic encephalomyelitis in rats
    • ROTT, O., FLEISCHER, B., and CASH, E. (1994). Interleukin-10 prevents experimental allergic encephalomyelitis in rats. Eur. J. Immunol. 24, 1434-1440.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1434-1440
    • Rott, O.1    Fleischer, B.2    Cash, E.3
  • 9
    • 0025892475 scopus 로고
    • Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β1
    • RACKE, M.K., JALBUT, S.D., CANNELLA, B., ALBERT, P.S., RAINE, C.S., and MCFARLIN, D.E. (1991). Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β1. J. Immunol. 146, 3012-3017.
    • (1991) J. Immunol. , vol.146 , pp. 3012-3017
    • Racke, M.K.1    Jalbut, S.D.2    Cannella, B.3    Albert, P.S.4    Raine, C.S.5    Mcfarlin, D.E.6
  • 11
    • 0028178443 scopus 로고
    • Transforming growth factor-β1 inhibits tumor necrosis factor-α/lymphotoxin production and adoptive transfer of disease by effector cells of autoimmune encephalomyelitis
    • STEVENS, D.B., GOULD, K.E., and SWANBORG, R.H. (1994). Transforming growth factor-β1 inhibits tumor necrosis factor-α/lymphotoxin production and adoptive transfer of disease by effector cells of autoimmune encephalomyelitis. J. Neuroimmunol. 51, 77-83.
    • (1994) J. Neuroimmunol. , vol.51 , pp. 77-83
    • Stevens, D.B.1    Gould, K.E.2    Swanborg, R.H.3
  • 12
    • 0028868821 scopus 로고
    • Expression of the inducible isoform of nitric oxide synthase in the central nervous system of mice correlates with the severity of actively induced experimental allergic encephalomyelitis
    • OKUDA, Y., NAKATSUJI, Y., FUJIMURA, H., ESUMI, H., OGURA, T., YANAGIHARA, T., and SAKODA, S. (1995). Expression of the inducible isoform of nitric oxide synthase in the central nervous system of mice correlates with the severity of actively induced experimental allergic encephalomyelitis. J. Neuroimmunol. 62, 103-112.
    • (1995) J. Neuroimmunol. , vol.62 , pp. 103-112
    • Okuda, Y.1    Nakatsuji, Y.2    Fujimura, H.3    Esumi, H.4    Ogura, T.5    Yanagihara, T.6    Sakoda, S.7
  • 13
    • 0028211518 scopus 로고
    • Target organ-specific up-regulation of MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with experimental autoimmune encephalomyelitis
    • WEINBERG, A.D., WALLIN, J.J., JONES, R.E., SULLIVAN, T.J., BOURDETTE, D.N., VANDENBARK, A.A., and OFFNER, H. (1994). Target organ-specific up-regulation of MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with experimental autoimmune encephalomyelitis. J. Immunol. 152, 4712-4721.
    • (1994) J. Immunol. , vol.152 , pp. 4712-4721
    • Weinberg, A.D.1    Wallin, J.J.2    Jones, R.E.3    Sullivan, T.J.4    Bourdette, D.N.5    Vandenbark, A.A.6    Offner, H.7
  • 14
    • 0028288512 scopus 로고
    • Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SJL/J mice
    • RENNO, T., LIN, J.Y., PICCIRILLO, C., ANTEL, J., and OWENS, T. (1994). Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SJL/J mice. J. Neuroimmunol. 49, 1-7.
    • (1994) J. Neuroimmunol. , vol.49 , pp. 1-7
    • Renno, T.1    Lin, J.Y.2    Piccirillo, C.3    Antel, J.4    Owens, T.5
  • 15
    • 0028983573 scopus 로고
    • TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis
    • RENNO, T., KRAKOWSKI, M., PICCIRILLO, C., LIN, J., and OWENS, T. (1995). TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. J. Immunol. 154, 944-953.
    • (1995) J. Immunol. , vol.154 , pp. 944-953
    • Renno, T.1    Krakowski, M.2    Piccirillo, C.3    Lin, J.4    Owens, T.5
  • 16
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • KENNEDY, M.K., TORRANCE, D.S., PICHA, K.S., and MOHLER, K.M. (1992). Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J. Immunol. 149, 2496-2505.
    • (1992) J. Immunol. , vol.149 , pp. 2496-2505
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 17
    • 0028806468 scopus 로고
    • Cytokine production in the central nervous system of Lewis rat with experimental autoimmune encephalomyelitis: Dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β
    • ISSAZADEH, S., LIUNGDAHL, Å., HOJEBERG, B., MUSTAFA, M., and OLSSON, T. (1995). Cytokine production in the central nervous system of Lewis rat with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β. J. Neuroimmunol. 61, 205-212.
    • (1995) J. Neuroimmunol. , vol.61 , pp. 205-212
    • Issazadeh, S.1    Liungdahl, Å.2    Hojeberg, B.3    Mustafa, M.4    Olsson, T.5
  • 18
    • 0028956025 scopus 로고
    • Interferon γ, interleukin 4 and transforming growth factor β in experimental autoimmune encephalomyelitis in Lewis rats: Dynamics of cellular mRNA expression in the central nervous system and lymphoid cells
    • ISSAZADEH, S., MUSTAFA, M., LIUNGDAHL, Å., HOJEBERG, B., DAGERLIND, Å., ELDE, R., and OLSSON, T. (1995). Interferon γ, interleukin 4 and transforming growth factor β in experimental autoimmune encephalomyelitis in Lewis rats: dynamics of cellular mRNA expression in the central nervous system and lymphoid cells. J. Neurosci. Res. 40, 579-590.
    • (1995) J. Neurosci. Res. , vol.40 , pp. 579-590
    • Issazadeh, S.1    Mustafa, M.2    Liungdahl, Å.3    Hojeberg, B.4    Dagerlind, Å.5    Elde, R.6    Olsson, T.7
  • 19
    • 0030248470 scopus 로고    scopus 로고
    • Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: Persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-β
    • ISSAZADEH, S., LORENTZEN, J.C., MUSTAFA, M.I., HOJEBERG, B., MUSSENER, Å., and OLSSON, T. (1996). Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-β. J. Neuroimmunol. 69, 103-115.
    • (1996) J. Neuroimmunol. , vol.69 , pp. 103-115
    • Issazadeh, S.1    Lorentzen, J.C.2    Mustafa, M.I.3    Hojeberg, B.4    Mussener, Å.5    Olsson, T.6
  • 20
    • 0030777027 scopus 로고    scopus 로고
    • High IL-6 and low IL-10 in the central nervous system are associated with protracted relapsing EAE in DA rats
    • DIAB, A., ZHU, J., XIAO, B.G., MUSTAFA, M., and LINKS, H. (1997). High IL-6 and low IL-10 in the central nervous system are associated with protracted relapsing EAE in DA rats. J. Neuropathol. Exp. Neurol. 56, 641-650.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 641-650
    • Diab, A.1    Zhu, J.2    Xiao, B.G.3    Mustafa, M.4    Links, H.5
  • 21
    • 0029058504 scopus 로고
    • Myelin oligodendrocyte glycoprotein induces a demyelinating encephalomyelitis resembling multiple sclerosis
    • JOHNS, T.G., KERLERO DE ROSBO, N., MENSON, K., ABO, S., GONZALES, M.F., and BERNARD, C.C.A. (1995). Myelin oligodendrocyte glycoprotein induces a demyelinating encephalomyelitis resembling multiple sclerosis. J. Immunol. 154, 5536-5541.
    • (1995) J. Immunol. , vol.154 , pp. 5536-5541
    • Johns, T.G.1    Kerlero De Rosbo, N.2    Menson, K.3    Abo, S.4    Gonzales, M.F.5    Bernard, C.C.A.6
  • 23
    • 0029038922 scopus 로고
    • b mice: Fine specificity and T cell receptor Vβ expression of encephalitogenic T cells
    • b mice: fine specificity and T cell receptor Vβ expression of encephalitogenic T cells. Eur. J. Immunol. 25, 1951-1959.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1951-1959
    • Mendel, I.1    Kerlero De Rosbo, N.2    Ben-Nun, A.3
  • 24
    • 0029821004 scopus 로고    scopus 로고
    • Antibody response in Lewis rats injected with myelin oligodendrocyte glycoprotein derived peptides
    • ICHIKAWA, M., JOHNS, T.G., MARTIN, A., and BERNARD, C.C.A. (1996). Antibody response in Lewis rats injected with myelin oligodendrocyte glycoprotein derived peptides. Int. Immunol. 8, 1667-1674.
    • (1996) Int. Immunol. , vol.8 , pp. 1667-1674
    • Ichikawa, M.1    Johns, T.G.2    Martin, A.3    Bernard, C.C.A.4
  • 25
    • 0031882899 scopus 로고    scopus 로고
    • Expression, purification and encephalitogenicity of recombinant human myelin oligodendrocyte glycoprotein
    • BETTADAPURA, J., MENSON, K.K., MORITZ, S., LIU, J., and BERNARD, C.C.A. (1998). Expression, purification and encephalitogenicity of recombinant human myelin oligodendrocyte glycoprotein. J. Neurochem. 70, 1593-1599.
    • (1998) J. Neurochem. , vol.70 , pp. 1593-1599
    • Bettadapura, J.1    Menson, K.K.2    Moritz, S.3    Liu, J.4    Bernard, C.C.A.5
  • 26
    • 0026713026 scopus 로고
    • Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, interleukin 4, and prostaglandin E expression in the brain
    • KHOURY, S.J., HANCOCK, W.W., and WEINER, H.L. (1992). Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, interleukin 4, and prostaglandin E expression in the brain. J. Exp. Med. 176, 1355-1364.
    • (1992) J. Exp. Med. , vol.176 , pp. 1355-1364
    • Khoury, S.J.1    Hancock, W.W.2    Weiner, H.L.3
  • 27
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • CHEN, Y., KUCHROO, V.K., INOBE, J., HAFLER, D.A., and WEINER, H.L. (1994). Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265, 1237-1240.
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 28
    • 0031011146 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis in IL-4-deficient mice
    • LIBLAU, R., STEINMAN, L., and BROCKE, S. (1997). Experimental autoimmune encephalomyelitis in IL-4-deficient mice. Int. Immunol. 9, 799-803.
    • (1997) Int. Immunol. , vol.9 , pp. 799-803
    • Liblau, R.1    Steinman, L.2    Brocke, S.3
  • 29
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • SELMAJ, K.W., and RAINE, C.S. (1988). Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann. Neurol. 23, 339-346.
    • (1988) Ann. Neurol. , vol.23 , pp. 339-346
    • Selmaj, K.W.1    Raine, C.S.2
  • 30
    • 0029410743 scopus 로고
    • Interferon-γ-induced oligodendrocyte cell death: Implications for the pathogenesis of multiple sclerosis
    • VARTANIAN, T., LI, Y., ZHAO, M., and STEFANSSON, K. (1995). Interferon-γ-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis. Mol. Med. 1, 732-743.
    • (1995) Mol. Med. , vol.1 , pp. 732-743
    • Vartanian, T.1    Li, Y.2    Zhao, M.3    Stefansson, K.4
  • 31
    • 0029671318 scopus 로고    scopus 로고
    • Mice with a disrupted IFN-γ gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
    • FERBER, I.A., BROCKE, S., EDWARDS, C.T., RIDGWAY, W., DINISCO, C., STEINMAN, L., DALTON, D., and FATHMAN, C.G. (1996). Mice with a disrupted IFN-γ gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J. Immunol. 156, 5-7.
    • (1996) J. Immunol. , vol.156 , pp. 5-7
    • Ferber, I.A.1    Brocke, S.2    Edwards, C.T.3    Ridgway, W.4    Dinisco, C.5    Steinman, L.6    Dalton, D.7    Fathman, C.G.8
  • 32
    • 0030587910 scopus 로고    scopus 로고
    • IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
    • WILLENBORG, D.O., FORDHAM, S., BERNARD, C.C.A., COWDEN, W.B., and RAMSHAW, I.A. (1996). IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J. Immunol. 157, 3223-3227.
    • (1996) J. Immunol. , vol.157 , pp. 3223-3227
    • Willenborg, D.O.1    Fordham, S.2    Bernard, C.C.A.3    Cowden, W.B.4    Ramshaw, I.A.5
  • 33
    • 0030918326 scopus 로고    scopus 로고
    • Tumor necrosis factor α and lymphotoxin α are not required for induction of acute experimental autoimmune encephalomyelitis
    • FREI, K., EUGSTER, H., BOPST, M., CONSTANTINESCU, C.S., LAVI, E., and FONTANA, A. (1997). Tumor necrosis factor α and lymphotoxin α are not required for induction of acute experimental autoimmune encephalomyelitis. J. Exp. Med. 185, 2177-2182.
    • (1997) J. Exp. Med. , vol.185 , pp. 2177-2182
    • Frei, K.1    Eugster, H.2    Bopst, M.3    Constantinescu, C.S.4    Lavi, E.5    Fontana, A.6
  • 35
    • 0038917435 scopus 로고    scopus 로고
    • Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting
    • KÖRNER, H., RIMINTON, D.S., STRICKLAND, D.H., LEMSKERT, F.A., POLLARD, J.D., and SEDGWICK, J.D. (1997). Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting. J. Exp. Med. 186, 1585-1590.
    • (1997) J. Exp. Med. , vol.186 , pp. 1585-1590
    • Körner, H.1    Riminton, D.S.2    Strickland, D.H.3    Lemskert, F.A.4    Pollard, J.D.5    Sedgwick, J.D.6
  • 36
    • 0030856118 scopus 로고    scopus 로고
    • A critical role for lymphotoxin in experimental allergic encephalomyelitis
    • SUEN, W.E., BERGMAN, C.M., HJELMSTRÖM, P., and RUDDLE, N.H. (1997). A critical role for lymphotoxin in experimental allergic encephalomyelitis. J. Exp. Med. 186, 1233-1240.
    • (1997) J. Exp. Med. , vol.186 , pp. 1233-1240
    • Suen, W.E.1    Bergman, C.M.2    Hjelmström, P.3    Ruddle, N.H.4


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