Secreted proteins of Mycobacterium leprae

Scandinavian Journal of Immunology

Volumn 48, Issue 6, 1998, Pages 577-584

  Harboe, M ^a,b   Wiker, H G ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b Inst of Immunology and Rheumatology   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; COMPLEMENTARY DNA; POLYPEPTIDE;

ARTICLE; DNA SEQUENCE; MYCOBACTERIUM; MYCOBACTERIUM LEPRAE; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECRETION; SEQUENCE HOMOLOGY;

ACYLTRANSFERASES; AMINO ACID SEQUENCE; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; LIPOPROTEINS; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM LEPRAE; MYCOBACTERIUM TUBERCULOSIS; PROTEIN SORTING SIGNALS; SOLUBILITY;

EID: 0031796967     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1998.00451.x     Document Type: Article

References (77)

1. Bloom BR, Murray CJ. Tuberculosis: commentary on a reemergent killer. Science 1992;257:1055-64.
2. Snider DE, Raviglione M, Kochi A. Global burden of tuberculosis. In: Bloom BR, ed. Tuberculosis: Pathogenesis, Protection and Control. Washington DC. American Society for Microbiology, 1994:3-11.
3. Harboe M. Leprosy. In: Lankinen KS, Bergström S, Mäkelä PH, Peltoma M, eds. Health and Disease in Developing Countries. London: Macmillan Press, 1994:255-264.
4. Wiker HG, Harboe M. The antigen 85 complex: a major secretion product of Mycobacterium tuberculosis. Microbiol Rev 1992; 56:648-61.
5. Andersen P. Effective vaccination of mice against Mycobacterium tuberculosis infection with a soluble mixture of secreted mycobacterial proteins. Infect Immun 1994;62:2536-44.
6. Haslov K, Andersen A, Nagai S, Gottschau A, Sørensen T, Andersen P. Guinea pig cellular immune responses to proteins secreted by Mycobacterium tuberculosis. Infect Immun 1995;63:804-10.
7. Orme IM. Induction of nonspecific acquired resistance and delayed-type hypersensitivity, but not specific acquired resistance in mice inoculated with killed mycobacterial vaccines. Infect Immun 1988; 56:3310-2.
8. Horwitz MA, Lee BW, Dillon BJ, Harth G. Protective immunity against tuberculosis induced by vaccination with major extracellular proteins of Mycobacterium tuberculosis. Proc Natl Acad Sci USA 1995;92:1530-4.
9. Daugelat S, Ladel CH, Kaufmann SH. Influence of mouse strain and vaccine viability on T-cell responses induced by Mycobacterium bovis bacillus Calmette-Guerin. Infect Immun 1995;63:2033-40.
10. Bjune G, Barnetson RS, Ridley DS, Kronvall G. Lymphocyte transformation test in leprosy: correlation of the response with inflammation of lesions. Clin Exp Immunol 1976;25:85-94.
11. Hess J, Gentschev I, Miko D et al. Superior efficacy of secreted over somatic antigen display in recombinant Salmonella vaccine induced protection against listeriosis. Proc Natl Acad Sci USA 1996;93: 1458-63.
12. Wiker HG, Harboe M, Nagai S. A localization index for distinction between extracellular and intracellular antigens of Mycobacterium tuberculosis. J Gen Microbiol 1991;137:875-84.
13. Borremans M, De Wit L, Volckaert G et al. Cloning, sequence determination, and expression of a 32- kilodalton-protein gene of Mycobacterium tuberculosis. Infect Immun 1989;57:3123-30.
14. De Wit L, de la Cuvellerie A, Ooms J, Content J. Nucleotide sequence of the 32 kDa-protein gene (antigen 85 A) of Mycobacterium bovis BCG. Nucl Acids Res 1990;18:3995.
15. Matsuo K, Yamaguchi R, Yamazaki A, Tasaka H, Yamada T. Cloning and expression of the Mycobacterium bovis BCG gene for extracellular alpha antigen. J Bacteriol 1988;170:3847-54.
16. De Wit L, Palou M, Content J. Nucleotide sequence of the 85B-protein gene of Mycobacterium bovis BCG and Mycobacterium tuberculosis. DNA Seq 1994;4:267-70.
17. Content J, de la Cuvellerie A, De Wit L, Vincent-Levy-Frebault V, Ooms J, De Bruyn J. The genes coding for the antigen 85 complexes of Mycobacterium tuberculosis and Mycobacterium bovis BCG are members of a gene family: cloning, sequence determination, and genomic organization of the gene coding for antigen 85-C of M. tuberculosis. Infect Immun 1991;59:3205-12.
18. Manca C, Lyashchenko K, Wiker HG, Usai D, Colangeli R, Gennaro ML. Molecular cloning, purification, and serological characterization of MPT63, a novel antigen secreted by Mycobacterium tuberculosis. Infect Immun 1997;65:16-23.
19. Terasaka K, Yamaguchi R, Matsuo K, Yamazaki A, Nagai S, Yamada T. Complete nucleotide sequence of immunogenic protein MPB70 from Mycobacterium bovis BCG. FEMS Microbiol Lett 1989;49:273-6.
20. Matsumoto S, Matsuo T, Ohara N et al. Cloning and sequencing of a unique antigen MPT70 from Mycobacterium tuberculosis H37Rv and expression in BCG using E. coli-mycobacteria shuttle vector. Scand J Immunol 1995;41:281-7.
21. Yamaguchi R, Matsuo K, Yamazaki A et al. Cloning and characterization of the gene for immunogenic protein MPB64 of Mycobacterium bovis BCG. Infect Immun 1989;57:283-8.
22. Oettinger T, Andersen ÅB. Cloning and B-cell-epitope mapping of MPT64 from Mycobacterium tuberculosis H37Rv. Infect Immun 1994;62:2058-64.
23. Ohara N, Kitaura H, Hotokezaka H et al. Characterization of the gene encoding the MPB51, one of the major secreted protein antigens of Mycobacterium bovis BCG, and identification of the secreted protein closely related to the fibronectin binding 85 complex. Scand J Immunol 1995;41:433-42.
24. Andersen ÅB, Hansen EB. Structure and mapping of antigenic domains of protein antigen b, a 38,000-molecular-weight protein of Mycobacterium tuberculosis. Infect Immun 1989;57:2481-8.
25. Laqueyrerie A, Militzer P, Romain F, Eiglmeier K, Cole S, Marchal G. Cloning, sequencing, and expression of the apa gene coding for the Mycobacterium tuberculosis 45/47-kilodalton secreted antigen complex. Infect Immun 1995;63:4003-10.
26. Wiker HG, Michell SL, Hewinson RG, Spierings E, Nagai S, Harboe M. Cloning, expression and significance of MPT53 for identification of secreted proteins of Mycobacterium tuberculosis. Submitted 1998.
27. Wiker HG, Harboe M, Nagai S, Patarroyo ME, Ramirez C, Cruz N. MPB59, a widely cross-reacting protein of Mycobacterium bovis BCG. Int Arch Allergy Appl Immunol 1986;81:307-14.
28. Pearson WR, Lipman DJ. Improved tools for biological sequence comparison. Proc Natl Acad Sci USA 1988;85:2444-8.
29. Lipman DJ, Pearson WR. Rapid and sensitive protein similarity searches. Science 1985;227:1435-41.
30. Higgins DG, Sharp PM. Fast and sensitive multiple sequence alignments on a microcomputer. Comput Appl Biosci 1989;5:151-3.
31. Wiker HG, Harboe M, Nagai S, Bennedsen J. Quantitative and qualitative studies on the major extracellular antigen of Mycobacterium tuberculosis H37Rv and Mycobacterium bovis BCG. Am Rev Respir Dis 1990;141:830-8.
32. Cole ST, Brosch R, Parkhill J et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 1998;393:537-44.
33. Belisle JT, Vissa VD, Sievert T, Takayama K, Brennan PJ, Besra GS. Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis. Science 1997;276:1420-2.
34. Abou-Zeid C, Ratliff TL, Wiker HG, Harboe M, Bennedsen J, Rook GA. Characterization of fibronectin-binding antigens released by Mycobacterium tuberculosis and Mycobacterium bovis BCG. Infect Immun 1988;56:3046-51.
35. Pessolani MC, Brennan PJ. Mycobacterium leprae produces extracellular homologs of the antigen 85 complex. Infect Immun 1992;60:4452-9.
36. Rinke de Wit TF, Clark-Curtiss JE, Abebe F et al. A Mycobacterium leprae-specific gene encoding an immunologically recognized 45 kDa protein. Mol Microbiol 1993;10:829-38.
37. Thole JE, Schoningh R, Janson AA et al. Molecular and immunological analysis of a fibronectin-binding protein antigen secreted by Mycobacterium leprae. Mol Microbiol 1992;6:153-63.
38. Matsuo K, Yamaguchi R, Yamasaki A, Tasaka H, Terasaka K, Yamada T. Cloning and expression of the gene for the cross-reactive alpha antigen of Mycobacterium kansasii. Infect Immun 1990; 58:550-6.
39. Kitaura H, Ohara N, Matsuo T, Tasaka H, Kobayashi K, Yamada T. Cloning, sequencing and expression of the gene for alpha antigen from Mycobacterium intracellulare and use of PCR for the rapid identification of Mycobacterium intracellulare. Biochem Biophys Res Commun 1993;196:1466-73.
40. Ohara N, Matsuo K, Yamaguchi R, Yamazaki A, Tasaka H, Yamada T. Cloning and sequencing of the gene for alpha antigen from Mycobacterium avium and mapping of B-cell epitopes. Infect Immun 1993;61:1173-9.
41. Takano M, Ohara N, Mizuno A, Yamada T. Cloning, sequencing and expression in Escherichia coli of the gene for alpha antigen from Mycobacterium scrofulaceum. Scand J Immunol 1994;40:165-70.
42. Nagai S, Wiker HG, Harboe M, Kinomoto M. Isolation and partial characterization of major protein antigens in the culture fluid of Mycobacterium tuberculosis. Infect Immun 1991;59:372-82.
43. Romain F, Augier J, Pescher P, Marchal G. Isolation of a proline-rich mycobacterial protein eliciting delayed-type hypersensitivity reactions only in guinea pigs immunized with living mycobacteria. Proc Natl Acad Sci USA 1993;90:5322-6.
44. Wieles B, van Agterveld M, Janson A et al. Characterization of a Mycobacterium leprae antigen related to the secreted Mycobacterium tuberculosis protein MPT32. Infect Immun 1994;62: 252-8.
45. Berthet FX, Rauzier J, Lim EM, Philipp W, Gicquel B, Portnoi D. Characterization of the Mycobacterium tuberculosis erp gene encoding a potential cell surface protein with repetitive structures. Microbiol 1995;141:2123-30.
46. Bigi F, Alito A, Fisanotti JC, Romano MI, Cataldi A. Characterization of a novel Mycobacterium bovis secreted antigen containing PGLTS repeats. Infect Immun 1995;63:2581-6.
47. Sonnenberg MG, Belisle JT. Definition of Mycobacterium tuberculosis culture filtrate proteins by two-dimensional polyacrylamide gel electrophoresis, N-terminal amino acid sequencing, and electrospray mass spectrometry. Infect Immun 1997;65:4515-24.
48. Closs O, Harboe M, Axelsen NH, Bunch-Christensen K, Magnusson M. The antigens of Mycobacterium bovis, BCG, studied by crossed immunoelectrophoresis: a reference system. Scand J Immunol 1980;12:249-63.
49. Manca C, Lyashchenko KP, Colangeli R, Gennaro ML. MTC28, a novel 28-kilodalton proline rich secreted antigen specific for the Mycobacterium tuberculosis complex. Infect Immun 1997;65:4951-7.
50. Young DB, Garbe TR. Lipoprotein antigens of Mycobacterium tuberculosis. Res Microbiol 1991;142:55-65.
51. Harboe M, Wiker HG. The 38-kDa protein of Mycobacterium tuberculosis: a review. J Infect Dis 1992;166:874-84.
52. Andersen ÅB, Ljungqvist L, Olsen M. Evidence that protein antigen b of Mycobacterium tuberculosis is involved in phosphate metabolism. J Gen Microbiol 1990;136:477-80.
53. Espitia C, Sciutto E, Bottasso O, Gonzalez-Amaro R, Hernandez-Pando R, Mancilla R. High antibody levels to the mycobacterial fibronectin-binding antigen of 30-31 kD in tuberculosis and lepromatous leprosy. Clin Exp Immunol 1992;87:362-7.
54. Ashbridge KR, Booth RJ, Watson JD, Lathigra RB. Nucleotide sequence of the 19 kDa antigen gene from Mycobacterium tuberculosis. Nucl Acids Res 1989;17:1249.
55. Hewinson RG, Michell SL, Russell WP, McAdam RA, Jacobs WR, Jr Molecular characterization of MPT83: a seroreactive antigen of Mycobacterium tuberculosis with homology to MPT70. Scand J Immunol 1996;43:490-9.
56. Matsuo T, Matsuo H, Ohara N et al. Cloning and sequencing of an MPB70 homologue corresponding to MPB83 from Mycobacterium bovis BCG. Scand J Immunol 1996;43:483-9.
57. Harboe M, Wiker HG, Ulvund G et al. MPB70 and MPB83 as indicators of protein localization in mycobacterial cells. Infect Immun 1998;66:289-96.
58. Oftung F, Wiker HG, Deggerdal A, Mustafa AS. A novel mycobacterial antigen relevant to cellular immunity belongs to a family of secreted lipoproteins. Scand J Immunol 1997;46:445-51.
59. Wu HC, Tokunaga M. Biogenesis of lipoproteins in bacteria. Curr Top Microbiol Immunol 1986;125:127-57.
60. Flynn JL, Goldstein MM, Triebold KJ, Koller B, Bloom BR. Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 1992;89:12013-7.
61. Kaufmann SH, Ladel CH. Role of T cell subsets in immunity against intracellular bacteria: experimental infections of knock-out mice with Listeria monocytogenes and Mycobacterium bovis BCG. Immunobiol 1994;191:509-19.
62. Harboe M, Andersen P, Colston MJ et al. European commission COST/STD initiative. Report of the expert panel IX. Vaccines against tuberculosis. Vaccine 1996;14:701-16.
63. Ladel CH, Blum C, Dreher A, Reifenberg K, Kaufmann SH. Protective role of gamma/delta T cells and alpha/beta T cells in tuberculosis. Eur J Immunol 1995;25:2877-81.
64. Dannenberg AM Jr, Rook GAW. Pathogenesis of pulmonary tuberculosis: an interplay of tissue-damaging and macrophage activating immune responses - dual mechanisms that control bacillary multiplication. In: Bloom BR ed. Tuberculosis: Pathogenesis, Protection and Control. Washington DC: American Society for Microbiology, 1994:459-83.
65. Mazzaccaro RJ, Gedde M, Jensen ER et al. Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 1996;93:11786-91.
66. Chambers MA, Marshall BG, Wangoo A et al Differential responses to challenge with live and dead Mycobacterium bovis Bacillus Calmette-Guerin. J Immunol 1997;158:1742-8.
67. Marques MA, Chitale S, Brennan PJ, Pessolani MC. Mapping and identification of the major cell wall-associated components of Mycobacterium leprae. Infection Immunity 1998;66:2625-31.
68. Rambukkana A, Burggraaf JD, Faber WR et al. The mycobacterial secreted antigen 85 complex possesses epitopes that are differentially expressed in human leprosy lesions and Mycobacterium leprae-infected armadillo tissues. Infect Immun 1993;61:1835-45.
69. Randall LL, Hardy SJ. Export of protein in bacteria. Microbiol Rev 1984;48:290-8.
70. Blight MA, Chervaux C, Holland IB. Protein secretion pathway in Escherichia coli. Curr Opin Biotechnol 1994;5:468-74.
71. Faith A, Moreno C, Lathigra R et al. Analysis of human T-cell epitopes in the 19,000 MW antigen of Mycobacterium tuberculosis: influence of HLA-DR. Immunol 1991;74:1-7.
72. Vordermeier HM, Harris DP, Friscia G et al. T cell repertoire in tuberculosis: selective anergy to an immunodominant epitope of the 38-kDa antigen in patients with active disease. Eur J Immunol 1992; 22:2631-7.
73. Lightbody KA, Girvin RM, Mackie DP, Neill SD, Pollock JM. T-cell recognition of mycobacterial proteins MPB70 and MPB64 in cattle immunised with antigen and infected with Mycobacterium bovis. Scand J Immunol 1998;48:44-51.
74. Andersen ÅB, Ljungqvist L, Hasløv K, Bentzon MW. MPB 64 possesses 'tuberculosis-complex'-specific B- and T-cell epitopes. Scand J Immunol 1991;34:365-72.
75. Cousins DV, Wilton SD, Francis BR. Use of DNA amplification for the rapid identification of Mycobacterium bovis. Vet Microbiol 1991;27:187-95.
76. Wiker HG, Harboe M, Bennedsen J, Closs O. The antigens of Mycobacterium tuberculosis, H37Rv, studied by crossed immunoelectrophoresis. Comparison with a reference system for Mycobacterium bovis, BCG. Scand J Immunol 1988;27:223-39.
77. Philipp WJ, Poulet S, Eiglmeier K et al. An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae. Proc Natl Acad Sci USA 1996;93:3132-7.