A comparative review of the newer inhalational anaesthetics

CNS Drugs

Volumn 10, Issue 4, 1998, Pages 287-310

  Young, Christopher J ^a   Apfelbaum, Jeffrey L ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; DESFLURANE; HALOTHANE; INHALATION ANESTHETIC AGENT; ISOFLURANE; NORADRENALIN; SEVOFLURANE;

DRUG APPROVAL; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; DRUG STABILITY; DRUG TOLERABILITY; DRUG TRANSFORMATION; HUMAN; INHALATION ANESTHESIA; MALIGNANT HYPERTHERMIA; OBSTETRIC ANESTHESIA; PRIORITY JOURNAL; REVIEW;

EID: 0031795445     PISSN: 11727047     EISSN: None     Source Type: Journal    
DOI: 10.2165/00023210-199810040-00006     Document Type: Review

References (363)

1. Haraguchi N, Furusawa H, Takezaki R, et al. Inhalational sedation with sevoflurane: a comparative study with nitrous oxide. J Oral Maxillofac Surg 1995; 53: 24-7
2. Lerman J, Gregory GA, Eger EI II. Hematocrit and the solubility of volatile anesthetics in blood. Anesth Analg 1984; 63: 911-4
3. Strum DP, Johnson BH, Eger EI II. Stability of sevoflurane in soda lime. Anesthesiology 1987; 67: 779
4. Cook TL, Beppu WJ, Hitt BA, et al. Renal effects and metabolism of sevoflurane in Fischer 344 rats: an in-vivo comparison with methoxyflurane. Anesthesiology 1975; 43: 70
5. Cook TL, Beppu WJ, Hitt BA, et al. A comparison of renal effects and metabolism of sevoflurane and methoxyflurane in enzyme-induced rats. Anesth Analg 1975; 54: 829-34
6. Martis L, Lynch S, Napoli MD, et al. Biotransformation of sevoflurane in dogs and rats. Anesth Analg 1981; 60: 186-91
7. Bito H, Ikeda K. Evaluation of low-flow sevoflurane anesthesia using modified Engstrom Elsa Anesthesia System. Masui 1994; 43: 1221-5
8. Bito H, Ikeda K. Long-duration, low-flow sevoflurane anesthesia using two carbon dioxide absorbents: quantification of degradation products in the circuit. Anesthesiology 1994; 81: 340-5
9. Bito H, Ikeda K. Closed-circuit anesthesia with sevoflurane in humans: effects on renal and hepatic function and concentrations of breakdown products with soda lime in the circuit. Anesthesiology 1994; 80: 71-6
10. Ruzicka JA, Hidalgo JC, Tinker JH, et al. Inhibition of volatile sevoflurane degradation product formation in an anesthesia circuit by a reduction in soda lime temperature. Anesthesiology 1994; 81: 238-44
11. Jin L, Baillie TA, Davis MR, et al. Nephrotoxicity of sevoflurane compound A [fluoromethyl-2,2-difluoro-1-(trifluoromethyl) vinyl ether] in rats: evidence for glutathione and cysteine conjugate formation and the role of renal cysteine conjugate beta-lyase. Biochem Biophysiol Res Comm 1995; 210(2): 498-506
12. Fang ZX, Eger EI II. Factors affecting the concentration of compound A resulting from the degradation of sevoflurane by soda lime and Baralyme in a standard anesthetic circuit. Anesth Analg 1995; 81 (3): 564-8
13. Keller KA, Callan C, Prokocimer P, et al. Inhalation toxicity study of a haloalkene degradant of sevoflurane, Compound A (PIFE), in Sprague-Dawley rats. Anesthesiology 1995; 83: 1220-32
14. Martin JL, Dodge ML, Pohl LR. Immunochemical detection of covalently modified kidney proteins in rats treated with the sevoflurane degradation product. Compound A (sevo-olefin) [abstract]. Anesthesiology 1994; 81: A436
15. Kandel L, Laster MJ, Eger EI II, et al. Nephrotoxicity in rats undergoing a one-hour exposure to compound A. Anesth Analg 1995; 81 (3): 559-63
16. Gonsowski CT, Laster MJ, Eger EI II, et al. Toxicity of compound A in rats: effect of increasing duration of administration. Anesthesiology 1994; 80: 566-73
17. Gonsowski CT, Laster MJ, Eger EI II, et al. Toxicity of compound A in rats: effect of a 3-hour administration. Anesthesiology 1994; 80: 556-65
18. Callan C, Prokicimer P, Delgado-Herrera L, et al. Effect of compound A on the kidney of Sprague-Dawley rats [abstract]. Anesthesiology 1994; 81: A1284
19. Frink Jr EJ, Green WB, Brown EA, et al. Sevoflurane degradation product concentration and hepatorenal function with soda lime in children [abstract]. Anesthesiology 1994; 81: A366
20. Martin JL, Laster MJ, Kandel L, et al. Metabolism of compound A by renal cysteine-S-conjugate beta-lyase is not the mechanism of compound A-induced renal injury in the rat. Anesth Analg 1996; 82: 770-4
21. Nakazawa M, Miyano K, Toriumi K, et al. Differential reactivities of three kinds of carbon dioxide absorbents with high concentration of sevoflurane. Masui 1994; 43: 1216-20
22. Foden ND, v Pelt FNAM, Jones RM. Dose dependent degradation of sevoflurane to compound A [abstract]. Anesthesiology 1994; 81: A432
23. Munday IT, Ward PM, Foden ND, et al. Sevoflurane degradation by soda lime in a circle breathing system. Anaesthesia 1996; 51: 622-6
24. Fang ZX, Kandel L, Laster MJ, et al. Factors affecting production of compound A from the interaction of sevoflurane with Baralyme and soda lime. Anesth Analg 1996; 82: 775-81
25. Munday IT, Foden ND, Ward PM, et al. Sevoflurane degradation in a circle system at 2 different fresh gas flow rates [abstract]. Anesthesiology 1994; 81: A433
26. Suzuki Y, Miyasaka K, Takata M, et al. Concentration of sevoflurane breakdown products with soda lime during 48 hour low-flow anesthesia in dogs [abstract]. Anesthesiology 1994; 81: A571
27. Frink Jr EJ, Isner RJ, Malan Jr TP, et al. Sevoflurane degradation product concentrations with soda lime during prolonged anesthesia. J Clin Anesth 1994; 6: 239-42
28. Zhang XF, Miyano K, Nakazawa M, et al. Differential reactivities of three kinds of carbon dioxide absorbents with sevoflurane. Masui 1994; 43: 378-82
29. Bito H, Ikeda K. Renal and hepatic function in surgical patients after low-flow sevoflurane or isoflurane anesthesia. Anesthesiology 1996; 82: 173-6
30. Frink Jr EJ, Green Jr WB, Brown EA, et al. Compound A concentrations during sevoflurane anesthesia in children. Anesthesiology 1996; 84: 566-71
31. Bito H, Ikeda K. Effect of total flow rate on the concentration of degradation products generated by reaction between sevoflurane and soda lime. Br J Anaesth 1995; 74: 667-9
32. Fang ZX, Eger EI II, Laster MJ, et al. Carbon monoxide production from degradation of desflurane, enflurane, isoflurane, halothane, and sevoflurane by soda lime and Baralyme. Anesth Analg 1995; 80: 1187-93
33. Kharasch ED. Biotransformation of sevoflurane. Anesth Analg 1995; 81 (6 Suppl.): S27-38
34. Kharasch ED, Karol MD, Lanni C, et al. Clinical sevoflurane metabolism and disposition: I. Sevoflurane and metabolite pharmacokinetics. Anesthesiology 1995; 82: 1369-78
35. Kharasch ED, Thummel KE. Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane. Anesthesiology 1993; 79: 795-807
36. Kharasch ED, Armstrong A, Gunn K, et al. Clinical sevoflurane metabolism and disposition: the role of cytochrome P4502EI [abstract]. Anesthesiology 1994; 81: A435
37. Kharasch ED, Armstrong AS, Gunn K, et al. Clinical sevoflurane metabolism and disposition. II. The role of cytochrome P450 2E1 in fluoride and hexafluoroisopropanol formation. Anesthesiology 1995; 82: 1379-88
38. Kharasch ED, Hankins DC, Thummel KE. Human kidney methoxyflurane and sevoflurane metabolism. Intrarenal fluoride production as a possible mechanism of methoxyflurane nephrotoxicity. Anesthesiology 1995; 82: 689-99
39. Green WB, Eckerson ML, Depa R, et al. Covalent binding of oxidative metabolites to hepatic protein not detectable after exposure to sevoflurane or desflurane [abstract]. Anesthesiology 1994; 81: A437
40. Aono J, Furuno K, Ueda W, et al. ICG disappearance rate during sevoflurane or neuroleptic anesthesia. Masui 1994; 43: 894-7
41. Malan Jr TP, Kadota Y, Mata H, et al. Renal function after sevoflurane or enflurane anesthesia in the Fischer 344 rat. Anesth Analg 1993; 77: 817-21
42. Payve AK, Morgan SE, Gandolfi AJ, et al. Biotransformation of sevoflurane by rat neonate liver slices. Drug Metab Dispos 1995; 23: 497-500
43. Kharasch ED. Metabolism and toxicity of the new anesthetic agents. Acta Anaesthesiol Belg 1996; 47: 7-14
44. Goldberg ME, Larijani GE, Cantillo C, et al. Time-course of elimination of serum inorganic fluoride ion following sevoflurane administration. Anesth Analg 1995; 80: S152
45. Funk W, Moldaschi J, Fushita Y, et al. Advantage of sevoflurane over halothane in anesthesia induction and emergence of pediatric patients [abstract]. Anesthesiology 1994; 81: A1315
46. Kataria B, Montana J. Inorganic fluoride levels alter inhalation of sevoflurane anesthetic in healthy children [abstract]. Anesthesiology 1994; 81: A1317
47. Gardner AM, Solomon DE, Gold M, et al. Sevoflurane vs isoflurane maintenance/recovery/fluoride concentrations/ length of exposure in elderly patients [abstract]. Anesthesiology 1994; 81: A8
48. DeSouza G, VandenBosch M, Dorta F, et al. A comparative study of sevoflurane and isoflurane for maintaining anesthesia in patients over 65 [abstract]. Anesthesiology 1991; 81: A7
49. Saitoh K, Hirabayashi Y, Fukuda H, et al. Sevoflurane anesthesia in patient following renal transplantation. Masui 1993; 42: 746-9
50. Min KT, Shin YS, Choi M, et al. Comparison of plasma inorganic fluoride concentration with sevoflurane-N2O and enflurane-N2O anesthesia. Yonsei Med J 1994; 35: 218-22
51. Goldberg ME, Cantillo J, Vekeman D, et al. Maintenance of anesthesia with sevoflurane: are serum fluoride levels of concern? [abstract]. Anesthesiology 1994; 81: A365
52. Munday IT, Stoddart PA, Jones RM, et al. Serum fluoride concentration and urine osmolality after enflurane and sevoflurane anesthesia in male volunteers. Anesth Analg 1995; 81: 353-9
53. Frink Jr EJ, Malan Jr TP, Brown HA, et al. Plasma inorganic fluoride levels with sevoflurane anesthesia in morbidly obese and nonobese patients. Anesth Analg 1993; 76: 1333-7
54. Malan TP, Sameshima T, Mata H. Concentration dependence of sevoflurane metabolism in rats [abstract]. Anesthesiology 1994; 81: A438
55. Bito H, Ikeda K. Plasma inorganic fluoride and intracircuit degradation product concentrations in long-duration, low-flow sevoflurane anesthesia. Anesth Analg 1994; 79: 946-51
56. Blanco E, Vidal MI, Blanco J, et al. Comparison of maintenance and recovery characteristics of sevoflurane-nitrous oxide and enflurane-nitrous oxide anaesthesia. Eur J Anaesthesiol 1995; 12: 517-23
57. Malan Jr TP, Sameshima T, Mata H, et al. Relationship of inspired anesthetic concentration to plasma concentration and urinary excretion of sevoflurane metabolites in rats. Anesth Analg 1995; 81: 576-80
58. Higuchi H, Arimura S, Sumikura H, et al. Urine concentration ability after prolonged sevoflurane anaesthesia. Br J Anaesth 1994; 73: 239-40
59. Frink Jr EJ, Malan Jr TP, Brown EA, et al. Renal concentrating functions with prolonged sevoflurane or enflurane anesthesia in volunteers. Anesthesiology 1994; 80: 1019-25
60. Wiesner G, Wild K, Schwurzer S, et al. Serum fluoride concentrations and exocrine kidney function with sevoflurane and enflurane: an open, randomized, comparative phase III study of patients with healthy kidneys. Anaesthesist 1996; 45: 31-6
61. Goldberg ME, Cantillo J, Larijani GE, et al. Sevoflurane versus isoflurane for maintenance of anesthesia: are serum inorganic fluoride ion concentrations of concern? Anesth Analg 1996; 82: 1268-72
62. Nishiyama T, Hirasaki A. Effects of sevoflurane anaesthesia on renal function - duration of administration and area under the curve and rate of decrease of serum inorganic fluoride. Eur J Anaesthesiol 1995; 12: 477-82
63. Higuchi H, Sumikura H, Sumita S, et al. Renal function in patients with high serum fluoride concentrations after prolonged sevoflurane anesthesia. Anesthesiology 1995; 83: 449-58
64. Suzuki K, Sun L, Takata M, et al. Effects of prolonged sevoflurane and isoflurane low-flow anesthesia: histopathologic study after 48-hour anesthesia in beagles [abstract]. Anesthesiology 1998; 83: A336
65. Lerman J, Sikich N, Kleinman S, et al. The pharmacology of sevoflurane in infants and children. Anesthesiology 1994; 80: 814-24
66. Taivainen T, Tiainen P, Meretoja OA, et al. Comparison of the effects of sevoflurane and halothane on the quality of anaesthesia and serum glutathione transferase alpha and fluoride in paediatric patients. Br J Anaesth 1994; 73: 590-5
67. Levine MF, Sarner J, Lerman J, et al. Plasma inorganic fluoride concentrations after sevoflurane anesthesia in children. Anesthesiology 1996; 84: 348-53
68. Matsumura C, Kemmotsu O, Kawano Y, et al. Serum and urine inorganic fluoride levels following prolonged low-dose sevoflurane anesthesia combined with epidural block. J Clin Anesth 1994; 6: 419-24
69. Gambling DR, Sharma SK, White PF, et al. A comparison of sevoflurane/N2O and isoflurane/N2O for cesarean birth: maternal effects and fluoride levels [abstract]. Anesthesiology 1994; 81: A1130
70. Higuchi H, Satoh T, Arimura S, et al. Serum inorganic fluoride levels in mildly obese patients during and after sevoflurane anesthesia. Anesth Analg 1993; 77: 1018-21
71. Stickler T, Callan C, Sayre J, et al. Incidence of inorganic fluoride concentrations 50 mmol/L in sevoflurane comparative clinical studies [abstract]. Anesthesiology 1994; 81: A1283
72. McGrath B, Hodgins L, Frink E, et al. The effect of sevoflurane vs. isoflurane on renal function in patients with renal insufficiency [abstract]. Anesth Analg 1995; 80: S312
73. Nuscheler M, Conzen PF, Melotte A, et al. Renal function after sevoflurane versus enflurane anesthesia in patients renal impairment [abstract]. Anesthesiology 1994; 81: A362
74. Melotte A, Verhagen M, Conzen P, et al. Plasma inorganic fluoride levels after sevoflurane or enflurane anesthesia in patients with renal impairment [abstract]. Anesthesiology 1994; 81: A368
75. Conzen PF, Nuscheler M, Melotte A, et al. Renal function and serum fluoride concentrations in patients with stable renal insufficiency after anesthesia with sevoflurane or enflurane. Anesth Analg 1995; 81: 569-75
76. Tsukamoto N, Hirabayashi Y, Shimizu R, et al. The effects of sevoflurane and isoflurane anesthesia on renal tubular function in patients with moderately impaired renal function. Anesth Analg 1996; 82: 909-13
77. Nishiyama T, Aibiki M, Hanaoka K. Inorganic fluoride kinetics and renal tubular function after sevoflurane anesthesia in chronic renal failure patients receiving hemodialysis. Anesth Analg 1996; 83: 574-7
78. 2) during anesthesia with isoflurane and sevoflurane. Masui 1994; 43: 67-71
79. Minoda Y, Sameshima T, Miyao J, et al. Effects of halogenated inhalational anesthetics on renal gamma glutamyl transpeptidase following renal ischemia [abstract]. Anesthesiology 1994; 81: A442
80. Tabo E, Ohkuma Y, Sudo S, et al. Multiple regression analysis of pre- and intra-operative factors in relation to post-operative liver and renal functions. Masui 1995; 44: 1482-8
81. Takeda J, Sato M, Shimada M, et al. Air pollution by sevoflurane in operating room and serum and urine inorganic fluoride of anesthetists. Masui 1995; 44: 1041-5
82. Yurino M, Kimura H. Vital capacity rapid inhalation induction technique: comparison of sevoflurane and halothane. Can J Anaesth 1993; 40: 440-3
83. Holaday DA, Smith FR. Clinical characteristics and biotransformation of sevoflurane in healthy human volunteers. Anesthesiology 1981; 54: 100-6
84. Tanaka S, Tsuchida H, Nakabayashi K, et al. The effects of sevoflurane, isoflurane, halothane, and enflurane on hemodynamic responses during an inhaled induction of anesthesia via a mask in humans. Anesth Analg 1996; 82: 721-6
85. Yurino M, Kimura H. A comparison of vital capacity breath and tidal breathing techniques: induction with high sevoflurane concentration in nitrous oxide and oxygen [abstract]. Anesthesiology 1994; 81: A4
86. Muzi M, Robinson BJ, Ebert TJ, et al. Induction of anesthesia and tracheal intubation with sevoflurane in adults. Anesthesiology 1996; 85: 536-43
87. Fragen RJ, Dunn K. Determination of the minimum alveolar concentration (MAC) of sevoflurane with and without nitrous oxide in elderly and young adults [abstract]. Anesthesiology 1994; 81: A361
88. Nagayama T, Meguro K, Inada Y. Sevoflurane MAC in the elderly. Masui 1994; 43: 238-41
89. Nakajima R, Nakajima Y, Ikeda K. Minimum alveolar concentration of sevoflurane in elderly patients. Br J Anaesth 1993; 70: 273-5
90. Katoh T, Ikeda K. The minimum alveolar concentration (MAC) of sevoflurane in humans. Anesthesiology 1987; 66: 301
91. Inomata S, Watanabe S, Taguchi M, et al. End-tidal sevoflurane concentration for tracheal intubation and minimum alveolar concentration in pediatric patients. Anesthesiology 1994; 80: 93-6
92. Taguchi M, Watanabe S, Asakura N, et al. End-tidal sevoflurane concentrations for laryngeal mask airway insertion and for tracheal intubation in children. Anesthesiology 1994; 81: 628-31
93. Katoh T, Suguro Y, Kimura T, et al. Cerebral awakening concentration of sevoflurane and isoflurane predicted during slow and fast alveolar washout. Anesth Analg 1993; 77: 1012-7
94. Katoh T, Suguro Y, Kimura T, et al. Morphine does not affect the awakening concentration of sevoflurane. Can J Anaesth 1993; 40: 825-8
95. Schwender D, Conzen P, Klasing S, et al. The effects of anesthesia with increasing end-expiratory concentrations of sevoflurane on midlatency auditory evoked potentials. Anesth Analg 1995; 81: 817-22
96. Tabo E, Ohkuma Y, Sakuragi Y, et al. MAC-awake and wake-up time of isoflurane and sevoflurane with reference to the concentration of gas, duration or inhalation and patients age and obesity [in Japanese]. Masui 1995; 44: 188-92
97. Yamamoto I, Yukioka H, Fujimori M. Clinical study of postoperative sedation in pediatric patients - effects of inhalation anesthetics and postoperative analgesics. Masui 1994; 43: 1191-5
98. Johnson JO, Sperry RJ, East KA. Efficacy of sevoflurane vs. isoflurane for maintenance of anesthesia during neurosurgical procedures [abstract]. Anesthesiology 1994; 81: A220
99. Eriksson H, Haasio J, Korttila K. Recovery from sevoflurane and isoflurane anaesthesia after outpatient gynaecological laparascopy. Acta Anesthesiol Scand 1995; 39 (3): 377-80
100. O'Hara DA, DeAngelis V, Lee H, et al. The effects of sevoflurane and isoflurane on recovery from outpatient surgery. Pharmacotherapy 1996; 16: 446-52
101. Scholz J, Bischoff P, Szafarczyk W, et al. Comparison of sevoflurane and isoflurane in ambulatory surgery: results of a mullicenter study. Anaesthesist 1996; 45 Suppl. 1: S63-70
102. Stead S, Miller J, Pregler J, et al. Recovery from sevoflurane and isoflurane anesthesia following prolonged exposure [abstract]. Anesth Analg 1995; 80: S468
103. Quinn, AC, Newman PJ, Hall GM, et al. Sevoflurane anaesthesia for major intra-abdominal surgery. Anaesthesia 1994; 49: 567-71
104. Binstock WB, Berkowitz R, Eyrich K, et al. A comparison of sevoflurane and halothane for induction and maintenance of anesthesia in pediatric ASA I and II outpatients [abstract]. Anesthesiology 1994; 81: A1313
105. Johannesson GP, Floren M, Lindahl SGE. Sevoflurane for ENT-surgery in children [abstract]. Anesthesiology 1994; 81: A1377
106. Sarner JB, Levine M, Davis PJ, et al. Clinical characteristics of sevoflurane in children: a comparison with halothane. Anesthesiology 1995; 82: 38-46
107. Mori N, Suzuki M. Sevoflurane in paediatric anaesthesia: effects on respiration and circulation during induction and recovery. Pediatr Anaesth 1996; 6: 95-102
108. Rieger A, Schroter G, Philippi W, et al. A comparison of sevoflurane with halothane in outpatient adenotomy in children with mild upper respiratory tract infections. J Clin Anesth 1996; 8: 188-97
109. Sury MR, Black A, Hemington L, et al. A comparison of the recovery characteristics of sevoflurane and halothane in children. Anaesthesia 1996; 51: 543-6
110. Black A, Sury MR, Hemington L, et al. A comparison of the induction characteristics of sevoflurane and halothane in children. Anaesthesia 1996; 51: 539-42
111. Meretoja OA, Taivainen T, Raiha L, et al. Sevoflurane-nitrous oxide or halothane-nitrous oxide for paediatric bronchoscopy and gastroscopy. Br J Anaesth 1996; 76: 767-71
112. Funk W, Moldaschl J, Fujita Y, et al. Sevoflurane or halothane in inhalational anesthesia induction in childhood: anesthesia quality and fluoride level. Anaesthesist 1996; 45: 22-30
113. Greenspun JC, Hannallah RS, Welborn LG, et al. Comparison of sevoflurane and halothane anesthesia in children undergoing outpatient ear, nose, and throat surgery. J Clin Anesth 1995; 7: 389-402
114. Stead SW, Miller J, Beatie CD, et al. Rapidity of induction and elimination of halothane and sevoflurane in pediatric outpatients [abstract]. Anesthesiology 1994; 81: A1314
115. Sloan MH, Conard PF, Karsunky PK, et al. Sevoflurane versus isoflurane: induction and recovery characteristics with single-breath inhaled inductions of anesthesia. Anesth Analg 1996; 82: 528-32
116. Yurino M, Kimura H. Efficient inspired concentration of sevoflurane for vital capacity rapid inhalation induction (VCRII) technique. J Clin Anesth 1995; 7: 228-31
117. Goyagi T, Kihara S, Harukuni I, et al. Comparison of airway complications on tracheal extubation in deeply sevoflurane anesthetized versus awake children. Masui 1995; 44: 1242-5
118. Nakae Y, Miyabe M, Sonoda H, et al. Comparison of intubating condition under sevoflurane and halothane anesthesia in pediatric patients. Masui 1995; 44: 239-43
119. Xiong J, Kurz A, Sessler DJ, et al. Isoflurane produces marked and nonlinear decreases in the vasoconstriction and shivering thresholds. Anesthesiology 1996; 85: 240-5
120. Lerman J, Davis PJ, Welborn LG, et al. Induction, recovery, and safety characteristics of sevoflurane in children undergoing ambulatory surgery: a comparison with halothane. Anesthesiology 1996; 84: 1332-40
121. Jellish WS, Lien CA, Fontenot HJ, et al. The comparative effects of sevoflurane versus propofol in the induction and maintenance of anesthesia in adult patients. Anesth Analg 1996; 82: 479-85
122. Yurino M, Kimura H. A comparison of vital capacity breath and tidal breathing techniques for induction of anaesthesia with high sevoflurane concentrations in nitrous oxide and oxygen. Anaesthesia 1995; 50: 308-11
123. Jellish WS, Lien C, Fonetot HJ, et al. Sevoflurane versus propofol for anesthesia induction and maintenance in adult inpatients [abstract]. Anesthesiology 1994; 81: A367
124. Huang S, Wong CH, Yang JC, et al. Comparison of emergence and recovery times between sevoflurane and propofol as maintenance anesthetics in adult outpatient surgeries [abstract]. Anesthesiology 1994; 81: A6
125. Lien C, Belmont M, Hemmings H, et al. Efficacy of sevoflurane versus propofol for the induction and maintenance of anesthesia [abstract]. Anesth Analg 1995; 80: S282
126. Pregler J, Stead SW, Beatie CD, et al. Return of cognitive functions after sevoflurane and propofol general anesthetics [abstract]. Anesthesiology 1994; 81: A1
127. Dubin SA, Huang S, Martin E, et al. Multicenter comparative study evaluating sevoflurane versus propotol in anesthesia maintenance and recovery in adult outpatients [abstract]. Anesthesiology 1994; 81: A2
128. Fredman B, Nathanson MH, Smith I, et al. Sevoflurane for outpatient anesthesia: a comparison with propotol. Anesth Analg 1995; 81; 823-8
129. Motsch J, Wandel C, Neff S, et al. A comparative study of the use of sevoflurane and propofol in ambulatory surgery. Anaesthesist 1996; 45 Suppl. 1: S57-62
130. Wandel C, Neff S, Bohrer H, et al. Recovery characteristics following anaesthesia with sevoflurane or propofol in adults undergoing out-patient surgery. Eur J Clin Pharmacol 1995; 48: 185-8
131. Tomi K, Mashimo Y, Tashiro C, et al. Alterations in pain threshold and psychomotor response associated with subanaesthetic concentrations of inhalation anaesthetics in humans. Br J Anaesth 1993; 70: 684-6
132. Smith I, Ding Y, White PF. Comparison of induction, maintenance, and recovery characteristics of sevoflurane-N2O and propofol-sevoflurane-N2O with propofol-isoflurane-N2O anesthesia. Anesth Analg 1992; 74: 253-9
133. Philip BK, Kallar SK, Bogetz MS, et al. A multicenter comparison of maintenance and recovery with sevoflurane or isoflurane for adult ambulatory anesthesia: the Sevoflurane Multicenter Ambulatory Group. Anesth Analg 1996; 83: 314-9
134. Eger EI II. Economic analysis and pharmaceutical policy: a consideration of the economics of the use of desflurane. Anaesthesia 1995; 50 Suppl.: 45-8
135. Loeb R, Wetchler BV, Schacher D, et al. Comparison of sevoflurane and isoflurane for anesthesia on adult outpatients [abstract]. Anesthesiology 1994; 81: A3
136. Johannesson GP, Floren M, Lindahl SG. Sevoflurane for ENT-surgery in children: a comparison with halothane. Acta Anaesthesiol Scand 1995; 39: 546-50
137. Malan TP, Dinardo JA, Frink EJ, et al. Cardiovascular effects of sevoflurane and isoflurane in volunteers [abstract]. Anesthesiology 1994; 81: A131
138. Kern C, Frei FJ. Hemodynamic responses to sevoflurane during inhalational induction in children [abstract]. Anesthesiology 1994; 81: A1316
139. Harkin CP, Pagel PS, Kersten JR, et al. Direct negative inotropic and lusitropic effects of sevoflurane. Anesthesiology 1994; 81: 156-67
140. Shigematsu T, Kobayashi M, Miyazama N, et al. Effects of sevoflurane on hemodynamics during the induction of anesthesia compared with those of isoflurane, enflurane, and halothane. Masui 1993; 42: 1748-53
141. Malan TP Jr, DiNardo JA, Isner RJ, et al. Cardiovascular effects of sevoflurane compared with those of isoflurane in volunteers. Anesthesiology 1995; 83: 918-28
142. Ebert TJ, Harkin CP, Muzi M. Cardiovascular responses to sevoflurane: a review. Anesth Analg 1995; 81 (6 Suppl.): S11-22
143. Epstein RH, Mendel HG, Guarnieri KM, et al. Sevoflurane versus halothane for general anesthesia in pediatric patients: a comparative study of vital signs, induction, and emergence. J Clin Anesth 1995; 7: 237-44
144. Rooke GA, Ebert T, Muzi M, et al. The hemodynamic and renal effects of sevoflurane and isoflurane in patients with coronary artery disease and chronic hypertension: Sevoflurane Ischemia Study Group. Anesth Analg 1996; 82: 1159-65
145. Park WK, Pancrazio JJ, Suh CK, et al. Myocardial depressant effects of sevoflurane: mechanical and electrophysiologic actions in vitro. Anesthesiology 1996; 84: 1166-76
146. Hettrick DA, Pagel PS, Warltier DC. Desflurane, sevoflurane, and isoflurane impair canine left ventricular-arterial coupling and mechanical efficiency. Anesthesiology 1996; 85: 403-13
147. Kanaya N, Kimura H, Miyamoto A, et al. Comparison of the effects of sevoflurane, isoflurane and halothane on the contractility of cultured rat myocardium [abstract]. Anesthesiology 1994; 81: A667
148. Hatakeyama N, Masuda H, Satone T, et al. Effects of sevoflurane on contraction, membrane ionic currents, and intracellular cyclic AMP concentration in canine single ventricular cells. Masui 1994; 43: 492-8
149. Hatakeyama N, Ito Y, Momose Y. Effects of sevoflurane, isoflurane, and halothane on mechanical and electrophysiologic properties of canine myocardium. Anesth Analg 1993; 76: 1327-32
150. Kikura M, Ikeda K. Comparison of effects of sevoflurane/nitrous oxide and enflurane/nitrous oxide on myocardial contractility in humans: load-independent and noninvasive assessment with transesophageal echocardiography. Anesthesiology 1993; 79: 235-43
151. Kitahata H, Tanaka K, Kimura H. Effects of sevoflurane on left ventricular diastolic function using transesophageal echocardiography. Masui 1993; 42: 358-64
152. Hatakeyama N, Momose Y, Ito Y. Effects of sevoflurane on contractile responses and electrophysiologic properties in canine single cardiac myocytes. Anesthesiology 1995; 82: 559-65
153. Holzman R, Vandervelde ME, Kaus SJ, et al. Sevoflurane depresses myocardial performance less than halothane during induction of anesthesia in pediatric patients [abstract]. Anesthesiology 1998; 83: A1169
154. Martin H, Gomez S, Qualis C, et al. Effects of isoflurane. sevoflurane, and desflurane on myocardial relaxation of stunned myocardium [abstract]. Anesthesiology 1998; 83: A582
155. Nakayama M, Fujita S, Kanaya N, et al. Blockade of adenosine triphosphate-sensitive K+ channel abolishes the protective effects of isoflurane in myocardial ischemia reperfusion [abstract]. Anesthesiology 1998; 83: A583
156. Iseki A, Doi T, Kimura H, et al. Isoflurane and sevoflurane impair left ventricular relaxation in dogs with fixed heart rate. Masui 1996; 45: 415-20
157. Skeehan TM, Schuler HG, Riley JL. Comparison of the alteration of cardiac function by sevoflurane, isoflurane, and halothane in the isolated working rat heart. J Cardiothorac Vasc Anesth 1995; 9: 706-12
158. Fujita Y, Yamasaki T, Takaori M. Sevoflurane anaesthesia for one-lung ventilation with PEEP to the dependent lung in sheep: effects on right ventricular function and oxygenation. Can J Anaesth 1993; 40: 1195-200
159. Hoffman WE, Charbel F, Edelman G. Brain tissue oxygen tension, carbon dioxide tension, and pH during increases in blood oxygen and carbon dioxide [abstract]. Anesthesiology 1995; 83: A521
160. Tomiyasu S, Hirano M, Fujigaki T, et al. Comparison of the systemic and coronary hemodynamic actions of sevoflurane- and isoflurane-induced controlled hypotension in dogs [abstract]. Anesthesiology 1995; 83: A607
161. Takahata O, Ichihara K, Ogawa H. Effects of sevoflurane on ischaemic myocardium in dogs. Acta Anaesthesiol Scand 1995; 39: 449-56
162. Hirano M, Fujigaki T, Shibata O, et al. A comparison of coronary hemodynamics during isoflurane and sevoflurane anesthesia in dogs. Anesth Analg 1995; 80: 651-6
163. Akata T, Kodama K, Takahashi S. Volatile anaesthetic actions on norepinephrine-induced contraction of small splanchnic-resistance arteries. Can J Anaesth 1995; 42: 1040-50
164. Az-ma T, Fujii K, Yuge O, et al. Single cell analyses of the effect of sevoflurane on bradykinin-induced calcium transients in cultured porcine aortic endothelial cells [abstract]. Anesthesiology 1994; 81: A862
165. Nakamura K, Terasako K, Toda H, et al. Mechanisms of inhibition of endothelium-dependent relaxation by halothane, isoflurane, and sevoflurane. Can J Anaesth 1994; 41: 340-6
166. Stekiel TA, Cotney SJ, Stekiel WJ, et al. The effect of sevoflurane on the in situ trans-membrane potential (Em) of vascular smooth muscle (VSM) [abstract]. Anesthesiology 1994; 81: A666
167. Lowe D, Hettrick DA, Pagel PS, et al. Influence of volatile anesthetics on left ventricular afterload in vivo. Differences between desflurane and sevoflurane. Anesthesiology 1996; 85: 112-20
168. Rodig G, Keyl C, Wiesner G, et al. Effects of sevoflurane and isoflurane on systemic vascular resistance: use of cardiopulmonary bypass as a study model. Br J Anaesth 1996; 76: 9-12
169. Hironaka Y, Iranami H, Yamada S, et al. Effects of isoflurane and sevoflurane on arteriovenous shunting in the foot of patients with and without diabetes [abstract]. Anesthesiology 1998; 83: A64
170. Tanaka S, Tsuchida H, Seki S, et al. Sevoflurane and halothane do not induce hyperdynamic responses during anesthesia induction [abstract]. Anesthesiology 1995; 83: A62
171. Ebert TJ, Muzi M, Lopatka CW. Effects of sevoflurane on hemodynamics and sympathetic neural activity in humans: a comparison to isoflurane [abstract]. Anesthesiology 1994; 81: A133
172. Hashimoto H, Imamura S, Ikeda K, et al. Electrophysiologic interaction between class I antiarrhythmic drugs and volatile anesthetics in depressant effects on ventricular activation in a canine myocardial infarction model. Jpn J Pharmacol 1994; 64: 235-41
173. Saeki Y, Hasegaqa Y, Shihamoto T, et al. The effects of sevoflurane, enflurane, and isoflurane on baroreceptor-sympathetic reflex in rabbits. Anesth Analg 1996; 82: 342-8
174. Ebert TJ, Muzi M, Lopatka CW. Neurocirculatory responses to sevoflurane in humans: a comparison to desflurane. Anesthesiology 1995; 83: 88-95
175. Imamura S, Ikeda K. Comparison of the epinephrine-induced arrhythmogenic effect of sevoflurane with isoflurane and halothane. J Anesth 1987; 1: 62
176. Navarro R, Weiskopf RB, Moore MA, et al. Humans anesthetized with sevoflurane or isoflurane have similar arrhythmic response to epinephrine. Anesthesiology 1994; 80: 545-9
177. Hikasa Y, Okabe C, Takase K, et al. Ventricular arrhythmogenic dose of adrenaline during sevoflurane, isoflurane, and halothane anaesthesia either with or without ketamine or thiopentone in cats. Res Vet Sci 1996; 60: 134-7
178. Fukuda H, Hirabayashi Y, Shimizu R, et al. Sevoflurane is equivalent to isoflurane for attenuating bupivacaine-induced arrhythmias and seizures in rats. Anesth Analg 1996; 83: 570-3
179. Novalija E, Kulier AH, Woehlck H, et al. Effects of desflurane, sevoflurane, and halothane on postinfarction spontaneous dysrhythmias in dogs [abstract]. Anesthesiology 1995; 83: A565
180. Kotake Y, Serita R, Ochiai R, et al. Effects of isoflurane and sevoflurane on neutrophil activation after abdominal aortic cross-clamp in rabbits [abstract]. Anesthesiology 1995; 83: A542
181. Oguchi T, Kashimoto S, Yamaguchi T, et al. Comparative effects of halothane, enflurane, isoflurane, and sevoflurane on function and metabolism in the ischaemic rat heart. Br J Anaesth 1995; 74: 569-75
182. Takahata O, Abiko Y, Obaga H. Effect of sevoflurane on regional myocardial blood flow under ischemia in dogs [abstract]. Anesthesiology 1994; 81: A670
183. Watanabe S, Hamada N, Tsuda H, et al. The effects of sevoflurane on the coronary circulation in the instrumented dog with or without coronary stenosis. Masui 1995; 44: 1080-90
184. Nakamura K, Toda H, Hatano Y, et al. Comparison of the direct effects of sevoflurane, isoflurane, and halothane on isolated canine coronary arteries. Can J Anaesth 1993; 40: 257-61
185. Kersten JR, Brayer AP, Pagel PS, et al. Perfusion of ischemic myocardium during anesthesia with sevoflurane. Anesthesiology 1994; 81: 995-1004
186. Watanabe S, Hamada N, Tsuda H. Sevoflurane does not show the coronary steal in dogs [abstract]. Anesthesiology 1995; 83: A650
187. Mizuno K, Stekiel AP, Pagel PS, et al. The inhibitory effect of sevoflurane on regulation of mesenteric capacitance veins and related reflex responses [abstract]. Anesthesiology 1994; 81: A665
188. Ebert TJ, Muzi M. Neurocirculatory responses to sevoflurane: a comparison to desflurane [abstract]. Anesthesiology 1995; 83: A68
189. Doi M, Takahashi T, Ikeda K. Respiratory effects of sevoflurane used in combination with nitrous oxide and surgical stimulation. J Clin Anesth 1994; 6: 1-4
190. Sarton E, Dahan A, Teppema L, et al. Acute pain and central nervous system arousal do not restore impaired hypoxic ventilatory response during sevoflurane sedation. Anesthesiology 1996; 85: 295-303
191. Hashimoto Y, Hirota K, Matsuki A, et al. Continuous measure ment of the bronchodilating effect of sevoflurane with a superfine bronchoscope [abstract]. Anesthesiology 1994; 81: A1438
192. Ohyama A, Arai K, Isa Y, et al. Comparison of the effects of halothane, isoflurane and sevoflurane in the treatment of severe asthmatic attack: a case report. Masui 1996; 45: 362-6
193. Mitsuhata H, Saitoh J Shimuzu R, et al. Sevoflurane and isoflurane protect against bronchospasm in dogs. Anesthesiology 1994; 81: 1230-4
194. Wiklund CU, Render CU, Ebberyd A, et al. Effects of sevoflurane on the isolated guinea pig trachea [abstract]. Anesthesiology 1994; 81: A1439
195. Ishibe Y, Gui X, Uno H, et al. Effect of sevoflurane on hypoxic pulmonary vasoconstriction in the perfused rabbit lung. Anesthesiology 1993; 79: 1348-53
196. Loer SA, Scheeren TW, Tarnow J. Desflurane inhibits hypoxic pulmonary vasoconstriction in isolated rabbit lungs. Anesthesiology 1995; 83: 552-6
197. Fukuda H, Kasuda H, Saitoh K, et al. Rapid induction of anesthesia with inhalation of sevoflurane. Masui 1993; 42: 1744-7
198. Doi M, Ikeda K. Airway irritation produced by volatile anaesthetics during brief inhalation: comparison of halothane, enflurane, isoflurane, and sevoflurane. Can J Anaesth 1993; 40: 122-6
199. Yamazaki M, Momose Y, Ito Y. Effects of sevoflurane or halothane on contractile responses of isolated canine basilar artery. Masui 1994; 43: 672-9
200. Johnson JO, Sperry RJ, Lam A, et al. A phase III, randomized, open-label study to compare sevoflurane and isoflurane in neurosurgical patients. Anesth Analg 1995; 80: S214
201. Takahashi H, Murata K, Ikeda K. Sevoflurane does not increase intracranial pressure in hyperventilated dogs. Br J Anaesth 1993; 71: 551-5
202. Kitaguchi K, Ohsumi H, Kuro M, et al. Effects of sevoflurane on cerebral circulation and metabolism in patients with ischemic cerebrovascular disease. Anesthesiology 1993; 79: 704-9
203. Cho S, Fujigaki T, Nishiwaki Y, et al. Effects of sevoflurane with and without N2O on human cerebral blood flow velocity response to CO2 [abstract]. Anesthesiology 1994; 81: A134
204. Fujibayashi T, Sugiura Y, Yanagimoto M, et al. Brain energy metabolism and blood flow during sevoflurane and halothane anesthesia: effects of hypocapnia and blood pressure fluctuations. Acta Anaesth Scand 1994; 38: 413-8
205. Kuroda Y, Murakami M, Tsuruta J, et al. Preservation of the ration of cerebral blood flow/metabolic rate for oxygen during prolonged anesthesia with isoflurane, sevoflurane, and halothane in humans. Anesthesiology 1996; 84: 555-61
206. McDonald T, Cunningham F, Berkowitz R. Comparative effects of sevoflurane and halothane on intraocular pressure in children undergoing endotracheal intubation [abstract]. Anesth Analg 1995; 80: S311
207. Artru AA. Rate of anterior chamber aqueous formation, trabecular outflow facility, and intraocular compliance during desflurane or halothane anesthesia in dogs. Anesth Analg 1995; 81: 585-90
208. Ogasawara H, Ishihara J, Matsuki A. Effect of sevoflurane anesthesia on catecholamine metabolism on rat brain [abstract]. Anesth Analg 1995; 80: S357
209. Ogasawara H, Takabashi S, Kudo T, et al. Effects of sevoflurane anesthesia on serotonin metabolism in rat brain. Masui 1993; 42: 1412-7
210. Nagasaka H, Kuroki K, Nakamura S, et al. Effects of sevoflurane on spinal dorsal horn WDR neuronal activity in cats. Masui 1993; 42: 1647-52
211. Ozaki M, Sessler DI, Suzuki H, et al. Nitrous oxide impairs thermoregulation less than sevoflurane [abstract]. Anesthesiology 1994; 81: A246
212. Hanagata K, Matsukawa T, Sessler DI, et al. Isoflurane and sevoflurane produce a dose-dependent reduction in the shivering threshold in rabbits. Anesth Analg 1995; 81: 581-4
213. Warner DS, McFarlane C, Todd MM, et al. Sevoflurane and halothane reduce focal ischemic brain damage in the rat: possible influence on thermoregulation. Anesthesiology 1993; 79: 985-92
214. Hashimoto K, Tanaka Y, Asahi N, et al. Convulsive seizure after craniotomy - comparison of isoflurane anesthesia and sevoflurane anesthesia. Masui 1995; 44: 1139-42
215. Schindler E, Thiel A, Muller M, et al. Changes in somatosensory evoked potentials after sevoflurane and isoflurane: a randomized phase III study. Anaesthesist 1996; 45 Suppl. 1: S52-6
216. Kameyama Y. Effect of isoflurane and sevoflurane on evoked potentials and EEG. Masui 1994; 43: 657-64
217. Nishiyama Y, Ito M. Effects of isoflurane, sevoflurane, and enflurane on median nerve somatosensory evoked potentials in humans. Masui 1993; 42: 339-43
218. Miyakawa H, Iwasaka H, Mori M, et al. The comparison of hypnotic potency of nitrous oxide with that of sevoflurane: evaluation by the middle latency auditory evoked response [in Japanese]. Masui 1995; 44: 522-5
219. Tatsumi K, Hirai K, Furuya H, et al. Effects of sevoflurane on the middle latency auditory evoked response and the electroencephalographic power spectrum. Anesth Analg 1995; 80: 940-3
220. Schwender D, Daunderer M, Klasing S, et al. Intraoperative awareness and auditory evoked potentials. Anaesthesist 1996; 45 Suppl. 1: S46-51
221. Kanaya N, Nakayama M, Fujita S, et al. Comparison of the effects of sevoflurane, isoflurane, and halothane on indocyanine green clearance. Br J Anaesth 1995; 74: 164-7
222. Frink Jr EJ, Malan Jr TP, Patel CB, et al. Hepatocellular function after sevoflurane or isoflurane anesthesia in cirrhotic patients [abstract]. Anesthesiology 1998; 83: A329
223. Crawford MW, Lerman J, Saldivia V, et al. Hemodynamic and organ blood flow response to halothane and sevoflurane anesthesia during spontaneous ventilation. Anesth Analg 1992 Dec: 75 (6): 1000-6
224. Kobayashi M. The effects of sevoflurane and isoflurane on hepatic blood flow in man. Masui 1996; 45: 281-6
225. Sugai M. Comparison of the effect of isoflurane and that of sevoflurane on hepatic circulation and oxygen metabolism during acute hypoxia in dogs. Masui 1996; 45: 608-16
226. Fukuda H, Saitoh K, Saitoh J, et al. Changes in plasma concentrations of human hepatocyte growth factor before and after major intra-abdominal surgery under nitrous oxide-sevoflurane anesthesia. Masui 1994; 43: 1556-9
227. Unoshima M, Iwasaka H, Miyakawa H, et al. Effect of prolonged sevoflurane anesthesia and surgery on insulin sensitivity [abstract]. Anesthesiology 1995; 83: A330
228. Sameshima T, Kadota Y, Miyao J, et al. Effects of sevoflurane anesthesia on the glucose and lipid metabolism in piglets [abstract]. Anesthesiology 1995; 83: A332
229. Hirakata H, Hara Y, Nakamura K, et al. Sevoflurane strongly suppresses human platelet aggression, possibly by inhibition of cyclooxygenase activity [abstract]. Anesthesiology 1995; 83: A340
230. Vanlinthout LE, Booij LH, van Egmond J, et al. Effect of isoflurane and sevoflurane on the magnitude and time course of neuromuscular block produced by vecuronium, pancuronium and atracurium. Br J Anaesth 1996; 76: 389-95
231. Kurahashi K, Maruta H. The effect of sevoflurane and isoflurane on the neuromuscular block produced by vecuronium continuous infusion. Anesth Analg 1996; 82: 942-7
232. Aziz L, Ohta Y, Nakatsuka H, et al. Effect of isoflurane and sevoflurane on the potencies of muscle relaxants in rat in vivo [abstract]. Anesth Analg 1995; 80: S26
233. Taivainen T, Meretoja OA. The neuromuscular blocking effects of vecuronium during sevoflurane, halothane and balanced anaesthesia in children. Anaesthesia 1995; 50: 1046-9
234. Nishiyama M, Mitani Y. Prolongation and recovery under sevoflurane anesthesia of neuromuscular blocking action of vecuronium. Masui 1994; 43: 45-9
235. Vanlinthout LEH, de Wolff MH, van Egmond J, et al. The effect of isoflurane and sevoflurane on the potency and the recovery of neuromuscular blockade by vecuronium, pancuronium, and atracurium [abstract]. Anesthesiology 1994; 81: A1113
236. Saitoh Y, Kaneda K, Toyooka H, et al. Post-tetanic count and single twitch height at the onset of reflex movement after administration of vecuronium under different types of anaesthesia. Br J Anaesth 1994; 72: 688-90
237. Morita T, Tsukagoshi H, Sagaya T, et al. The effects of sevoflurane are similar to those of isoflurane on the neuromuscular block produced by vecuronium. Br J Anaesth 1994; 72: 465-7
238. Morita T, Tsukagoshi H, Sugaya T, et al. Inadequate antagonism of vecuronium-induced neuromuscular block by neostigmine during sevoflurane or isoflurane anesthesia. Anesth Analg 1995; 80: 1175-80
239. Ochiai R, Toyoda Y, Nishio I, et al. Possible association of malignant hyperthermia with sevoflurane anesthesia. Anesth Analg 1992; 74: 616-8
240. Otsuka H, Komura Y, Mayumi T, et al. Malignant hyperthermia during sevoflurane anesthesia in a child with central core disease. Anesthesiology 1991; 74: 699-701
241. Komatsu H, Enzan K, Suzuki M. A case of abortive malignant hyperthermia during funnel chest surgery. Masui 1993; 42: 1053-5
242. Ducart A, Adnet P, Renaud B, et al. Malignant hyperthermia during sevoflurane administration. Anesth Analg 1995; 80: 609-11
243. Gambling DR, Sharma SK, White PF, et al. Use of sevoflurane during elective cesarean birth: a comparison with isoflurane and spinal anesthesia. Anesth Analg 1995; 81: 90-5
244. Murakawa T, Kudo T, Kudo M, et al. Plasma catecholamine levels in patients during surgical removal of pheochromocytoma under sevoflurane anesthesia. Masui 1994; 43: 823-9
245. Yamaguchi S, Gushiken T, Kawakami M, et al. Anesthetic management of a patient with congenital cystic adenomatoid malformation. Masui 1995; 44: 1689-91
246. Kawahito S, Kitahata H, Kimura H, et al. Bronchospasm during anesthesia in a patient with Prader-Willi syndrome. Masui 1995; 44: 1675-9
247. Shiraishi N, Takakuwa K, Yamamoto N, et al. Anesthetic management of Seckel syndrome: a case report. Masui 1995; 44: 735-8
248. Yasui Y, Yamamoto Y, Sodeyama O, et al. Anesthesia in a patient with epidermolysis bullosa. Masui 1995; 44: 260-2
249. Ii C, Tanaka N, Okamura H, et al. Anesthetic management of a patient with acute intermittent porphyria. Masui 1993; 42: 1849-52
250. Kurahashi K, Andoh T, Sato K, et al. Anesthesia in a patient with carnitine deficiency syndrome. Masui 1993; 42: 1223-6
251. Iida R, Nagai H, Iwasaki K, et al. Anesthetic management of a patient with ornithine transcarbamylase deficiency. Masui 1996; 45: 642-5
252. Masuda Y, Hayashi M, Ohara H. Sevoflurane anesthesia for a patient with facioscapulohumeral muscle dystrophy. Masui 1994; 43: 580-3
253. Kohno K, Uchida H, Yamamoto N, et al. Sevoflurane anesthesia in a patient with multiple sclerosis. Masui 1994; 43: 1229-32
254. Murakawa T, Kudo T, Kudo M, et al. Hormonal changes during removal of aldosterone-producing adrenal tumor under sevoflurane anesthesia. Masui 1994; 43: 1529-33
255. Iwashita H, Matsukawa T, Ookawa I, et al. Anesthetic management of a patient with cardiac sarcoidosis. Masui 1995; 44: 1692-4
256. Ueda Y, Okamoto T, Satoh T. General anesthesia conducted twice in myotonic dystrophy. Masui 1993; 42: 742-5
257. Tanaka K, Nakamura M, Domen M, et al. The influence of volatile anesthetics on portwine stain. Clin Ther 1993; 15: 567-9
258. Arimitsu M, Izumi T, Okudo T, et al. Obliterating effects of sevoflurane on port-wine stains [abstract]. Anesthesiology 1995; 83: A1163
259. Kudoh A, Hiroto K, Sakai T, et al. Effect of sevoflurane anesthesia on plasma CK, GOT, GPT, LDH levels in children: a comparison with isoflurane [abstract]. Anesth Analg 1995; 80: S256
260. Kudoh A, Sakai T, Matsuki A. A marked elevation in serum CPK following sevoflurane anesthesia. Masui 1994; 43: 246-9
261. Eger EI II. Partition coefficients for I-653 in human blood, saline and olive oil. Anesth Analg 1987; 66: 971-3
262. Graf BM, Boban M, Stowe DF, et al. Lack of stereospecific effects of isoflurane and desflurane isomers in isolated guinea pig hearts. Anesthesiology 1994; 81: 129-36
263. Weiskopf RB, Sampson D, Moore MA. The desflurane (Tec 6) vaporizer: design, design considerations, and performance evaluation. Br J Anaesth 1994; 72: 474-9
264. Johnston Jr RV, Andrews JJ, Deyo DJ, et al. The effects of carrier gas composition on the performance of the Tec 6 desflurane vaporizer. Anesth Analg 1994; 79: 548-52
265. Bunting HE, Kelly MC, Milligan KR. Effect of nebulized lignocaine on airway irritation and haemodynamic changes during induction of anaesthesia with desflurane. Br J Anaesth 1995; 75: 631-3
266. Eger EI II. Stability of I-653 in soda lime. Anesth Analg 1987; 66: 983-5
267. Kohlin FF, Eger EI II, Johnson BH, et al. I-653 resists degradation in rats. Anesth Analg 1988; 67: 534-8
268. Eger EI II, Johnson BH, Strum DP, et al. Studies of the toxicity of I-653, halothane, and isoflurane in enzyme-induced, hypoxic rats. Anesth Analg 1987; 66: 1227-9
269. Frink EJ, Nogami WM, Morgan SE, et al. High carboxyhemoglobin concentrations occur in swine during desflurane anesthesia in the presence of partially dried carbon dioxide absorbents. Anesthesiology 1997; 87: 308-16
270. Moon RE. Cause of CO poisoning, relation to halogenated agents still not clear. APSF Newsletter 1994; 9: 13-24
271. Rampil IJ, Zwass M, Lockhart S, et al. MAC of I-653 in surgical patients [abstract]. Anesthesiology 1989; 71: A269
272. Jones RM, Cashman JN, Eger EI II, et al. Kinetics and potency of I-653 in volunteers [abstract]. Anesthesiology 1989; 71: A270
273. Mapleson WW. Effect of age on MAC in humans: a meta-analysis. Br J Anaesth 1996; 76: 179-85
274. Gold MI, Abello D, Herrington C. Minimum alveolar concentration of desflurane in patients older than 65 yr. Anesthesiology 1993; 79: 710-4
275. Kelly RE, Hartman GS, Embree PP, et al. Inhaled induction and emergence from desflurane anesthesia in the ambulatory surgical patient: the effect of premedication. Anesth Analg 1993; 77: 540-3
276. Bernards CM, Cullen BF, Powers KM. Chronic cocaine administration does not alter desflurane mac in the rat [abstract]. Anesthesiologv 1994; 81: A444
277. Chortkoff BS, Eger EI II, Crankshaw DP, et al. Concentrations of desflurane and propofol that suppress response to command in humans. Anesth Analg 1995; 81: 737-43
278. Chortkoff BS, Gonsowski CT, Bennett HL, et al. Subanesthetic concentrations of desflurane and propofol suppress recall of emotionally charged information. Anesth Analg 1995; 81: 728-36
279. Gonsowski CT, Chortkoff BS, Eger EI II, et al. Subanesthetic concentrations of desflurane and isoflurane suppress explicit and implicit learning. Anesth Analg 1995; 80: 568-72
280. Schwender D, Klasing S, Conzen P, et al. Midlatency auditory evoked potentials during anaesthesia with increasing end expiratory concentrations of desflurane. Acta Anaesthesiol Scand 1996; 40: 171-6
281. Hargasser S, Hipp R, Breinhauer B, et al. A lower solubility recommends the use of desflurane more than isoflurane, halothane, and enflurane under low-flow conditions. J Clin Anesth 1995; .7: 49-53
282. Bennett JA, Mahadeviah A, Stewart J, et al. Desflurane controls the hemodynamic response to surgical stimulation more rapidlt than isoflurane. J Clin Anesth 1995; 7: 288-91
283. Wiesner G, Wild K, Merz M, et al. Rates of awakening, circulatory parameters and side-effects with sesoflurane and enflurane: an open, randomized, comparative phase III study. Anasthesiol Intensivmed Notfallmed Schmerzther 1995; 30: 290-6
284. Eger EI II, Johnson BH. Rates of awakening from anesthesia with I-653, halothane, isoflurane, and sevodurane: a test of the effect of anesthetic concentration and duration in rats. Anesth Analg 1987; 66: 977-82
285. Welborn LG, Frazier LJ, Hannallah RS, et al. Comparison of emergence and recovery characteristics of sevoflurane, desflurane, and halothane in pediatric patients [abstract]. Anesth Analg 1995; 8.: S550
286. Nash JA, Stevens WC, Au Y-H. Desflurane and isoflurane induction rates using a closed circle system [abstract]. Anesthesiology 1994; 81: A369
287. Nathanson MH, Fredman B, Smith I, et al. Sevoflurane versus desflurane for outpatient anesthesia: a comparison of maintenance and recovery profiles. Anesth Analg 1995; 81: 1186-90
288. Smith I, Taylor E, White PF. Comparison of tracheal extubation in patients deeply anesthetized with desflurane or isoflurane. Anesth Analg 1994; 79: 642-5
289. Weiskopf RB, Moore MA, Eger II EI, et al. Rapid increase in desflurane concentration is associated with greater transient cardiovascular stimulation than with rapid increase in isoflurane concentration in humans. Anesthesiology 1994; 80: 1035-45
290. Bennett JA, Lingaraju N, Horrow JC, et al. Elderly palients recovery more rapidly from desflurane than from isoflurane anesthesia. J Clin Anesth 1992; 4: 378-81
291. Davis PJ, Cohen IT, McGowan Jr FX, et al. Recovery characteristics of desflurane versus halothane for maintenance of anesthesia in pediatric ambulatory patients. Anesthesiology 1994; 80: 298-302
292. Loscar M, Allhoff, Ott H, et al. Awakening from anesthesia and recovery of cognitive function after desflurane or isoflurane. Anaesthesist 1996; 45: 140-5
293. Graham SG, Aitkenhead AR. A comparison between propofol and desflurane anaesthesia for minor gynaecological laparoscopic surgery. Anaesthesia 1993; 48: 471-5
294. Rosenberg MK, Bridge P, Brown M. Cost comparison: a desflurane- versus a propofol-based general anesthetic technique. Anesth Analg 1994; 79: 852-5
295. Wilhelm W, Kuster M, Larsen B, et al. Desflurane and isoflurane: a comparison of recovery and circulatory parameters in surgical interventions. Anaesthesist 1996; 45: 37-46
296. Wolf AR, Lawson RA, Dryden CM, et al. Recovery after desflurane anaesthesia in the infant: comparison with isoflurane. Br J Anaesth 1996; 76: 362-4
297. Loan PB, Mirakhur RK, Paxton LD, et al. Comparison of desflurane and isoflurane in anaesthesia for dental surgery. Br J Anaesth 1995; 75: 289-92
298. Dexter F, Tinker JH. Comparisons between desflurane and isoflurane or propofol on time to following commands and time to discharge: a metaanalysis. Anesthesiology 1995; 83: 77-82
299. Gupta A, Kullander M, Ekberg K, et al. Anaesthesia for day-care arthroscopy: a comparison between desflurane and isoflurane. Anaesthesia 1996; 51: 56-62
300. Patel SS, Goa KL. Desflurane: a review of its pharmacodynamic and pharmacokinetic properties and its efficacy in general anaesthesia. Drugs 1995; 50: 742-67
301. Eriksson H, Kortlila K. Recovery profile after desflurane with or without ondansetron compared with propofol in patients undergoing outpatient gynecological laparoscopy. Anesth Analg 1996; 82: 533-8
302. Szocik JF, Powell B. A comparison of theoretical vs. actual cost of desflurane [abstract]. Anesthesiology 1994; 81: A536
303. Weiskopf RB, Eger EI II. Comparing the costs of inhaled anesthetics. Anesthesiology 1994; 79: 1413-8
304. Smith CE, Patel N, Sidhu T, et al. Does desflurane affect operating room turnover time in an ambulatory care unit [abstract]. Anesthesiology 1994; 81: A37
305. Patel N, Smith CE, Pinchak AC, et al. Desflurane is not associated with faster operating room exit times in outpatients. J Clin Anesth 1996; 8: 130-5
306. Pacentine GG, Muzi M, Ebert TJ. Effects of fentanyl on sympathetic activation associated with the administration of desflurane. Anesthesiology 1995; 82: 823-31
307. Weiskopf RB, Holmes MA, Eger EI II. Cardiovascular effects of I-653 in swine. Anesthesiology 1988; 69: 303-9
308. Pagel PS, Kampine JP, Schmeling WT, et al. Evaluation of myocardial contractility in the chronically instrumented dog with intact autonomic nervous system function: effects of desflurane and isoflurane. Acta Anaesthesiol Stand 1993; 37: 203-10
309. McMurphy RM, Hodgson DS. Cardiopulmonary effects of desflurane in cats. Am J Vet Res 1996; 57: 367-70
310. Sundeman H, Biber B, Martner J, et al. Vasodilator effects of desflurane and isoflurane in the feline small intestine. Acta Anaesthesiol Scand 1995; 39: 1105-10
311. Hartman JC, Pagel PS, Proctor LT, et al. Influence of desflurane, isoflurane, and halothane on regional tissue perfusion in dogs. Can J Anaesth 1993; 39: 877-87
312. Mignella R, Buffington C. Desflurane decreases collateral blood flow in a model of chronic coronary occlusion [abstract]. Anesthesiology 1994; 81: A661
313. Pagel PS, Hettrick DA, Lowe D, et al. Desflurane and isoflurane exert modest beneficial actions on left ventricular diastolic function during myocardial ischemia in dogs. Anesthesiology 1995; 83: 1021-35
314. Mignella R, Bufington CW. Inhaled anesthetics alter the determinants of coronary collateral blood flow in the dog. Anesthesiology 1995; 83: 799-808
315. Armbruster K, Dressler IMJ, Haberstroh J, et al. Effects of desflurane on hemodyanics and oxygenation of liver and small intestine [abstract]. Anesthesiology 1994; 81: A663
316. Moore MA, Weiskopf RB, Eger EI II, et al. Arrhythmogenic doses of epinephrine are similar during desflurane or isoflurane anesthesia in humans. Anesthesiology 1993; 79: 943-7
317. Helman JD, Leung JM, Bellows WH, et al. The risk of myocardial ischemia in patients receiving desflurane versus sufentanil anesthesia for coronary artery bypass graft surgery: the S.P.I. Research Group. Anesthesiology 1992; 77: 47-62
318. Parsons RS, Jones RM, Wrigley SR, et al. Comparison of desflurane and fentanyl-based anaesthetic techniques for coronary artery bypass surgery. Br J Anaesth 1994; 72: 430-8
319. Boban N, McCallum JB, Schedewie HK, et al. Direct comparative effects of isoflurane and desflurane on sympathetic ganglionic transmission. Anesth Analg 1995; 80: 127-34
320. Muzi M, Lopatka CW, Ebert TJ. Desflurane-mediated neurocirculatory activation in humans: effects of concentration and rate of change on responses. Anesthesiology 1996; 84: 1035-42
321. Muzi M, Ebert TJ, Hope WG, et al. Site(s) mediating sympathetic activation with desflurane. Anesthesiology 1996; 85: 737-47
322. Weiskopf RB, Eger EI II, Daniel M, et al. Cardiovascular stimulation induced by rapid increases in desflurane concentration in humans results from activation of tracheopulmonary and systemic receptors. Anesthesiology 1995; 83: 1173-8
323. Muzi M, Ebert TJ. A comparison of baroreflex sensitivity during isoflurane and desflurane anesthesia in humans. Anesthesiology 1995; 82: 919-25
324. Dahan A, Sarton E, van den Elsen M, et al. Ventilatory response to hypoxia in humans: influences of subanesthetic desflurane. Anesthesiology 1996; 85: 60-8
325. Moore MA, Weiskopf RB, Eger EI II, et al. Rapid 1% increases of end-tidal desflurane concentration to greater than 5% transiently increase heart rate and blood pressure in humans. Anesthesiology 1994; 81: 94-8
326. Weiskopf RB, Eger EI II, Noorani M, et al. Repetitive rapid increases in desflurane concentration blunt transient cardiovascular stimulation in humans. Anesthesiology 1994; 81: 843-9
327. Yonker-Sell A, Muzi M, Lopatka CW, et al. Desflurane produces greater sympathetic excitation than isoflurane during slow, controlled increases. Anesth Analg 1995; 80: S571
328. Muzi M, Pacentine GG, Lopatka CW, et al. Lidocaine airway anesthesia does not attenuate sympathetic activation during desflurane administration [abstract]. Anesthesiology 1994; 81: A370
329. Devcic A, Muzi M, Foley P, et al. The effects of clonidine on desflurane-mediated sympatho-excitation in humans [abstract]. Anesthesiology 1994; 81: A358
330. Weiskopf RB, Eger EI II, Noorani M, et al. Fentanyl, esmolol, and clonidine blunt the transient cardiovascular stimulation induced by desflurane in humans. Anesthesiology 1994; 81: 1350-5
331. Devcic A, Muzi M, Ebert TJ. The effects of clonidine on desflurane-mediated sympathoexcitation in humans. Anesth Analg 1995; 80: 773-9
332. Gormley WP, Murray JM, Trinick TR. Intravenous lidocaine does not attenuate the cardiovascular and catecholamine response to a rapid increase in desflurane concentration. Anesth Analg 1996; 82: 358-61
333. Yonker-Sell AE, Muzi M, Hope WG, et al. Alfentanil modifies the neurocirculatory responses to desflurane. Anesth Analg 1996; 82: 162-6
334. Ebert TJ, Lopatka CW, Muzi M, et al. The efficacy of propofol vs. etomidate in reducing desflurane-mediated sympathetic hyperactivity in humans [abstract]. Anesthesiology 1994; 81: A137
335. Daniel M, Eger EI II, Weiskopf RB, et al. Propofol fails to attenuate the cardiovascular response to rapid increases in desflurane concentration. Anesthesiology 1996; 84: 75-80
336. Daniel M, Larson MD, Eger EI II, et al. Fentanyl, clonidine, and repeated increases in desflurane concentration, but not nitrous oxide or esmolol, block the transient mydriasis caused by rapid increases in desflurane concentration. Anesth Analg 1995; 8: 372-8
337. Kersten J, Pagel PS, Tessmer JP, et al. Dexmedetomidine alters the hemodynamic effects of desflurane and isoflurane in chronically instrumented dogs. Anesthesiology 1993; 79: 1022-32
338. Lippmann M, Ford M, Lee C, et al. Use of desflurane during resection of phaeochromocytoma. Br J Anaesth 1994; 72: 707-9
339. Lu GP, Gevirtz C, Gibson JA, et al. Effect of desflurane on cerebral blood flow and microcirculation [abstract]. Anesthesiology 1994; 81: A662
340. Matta BF, Mayberg TS, Lam AM. Direct cerebrovasodilatory effects of halothane, isoflurane, and desflurane during propofol-induced isoelectric electroencephalogram in humans. Anesthesiology 1995; 83: 980-5
341. Ornstein E, Young WL, Fleischer LH, et al. Desflurane and isoflurane have similar effects on cerebral blood flow in patients with intracranial mass lesions. Anesthesiology 1993; 79: 498-503
342. Artru AA, Powers K, Doepfner P. CSF, sagittal sinus, and jugular venous pressures during desflurane or isoflurane anesthesia in dogs. J Neurosurgical Anesthesiology 1994; 6: 239-48
343. Strebel S, Lam AM, Matta B, et al. Dynamic and static cerebral autoregulation during isoflurane, desflurane, and propofol anesthesia. Anesthesiology 1995; 83: 66-76
344. Artru AA. Intracranial volume/pressure relationship during desflurane anesthesia in dogs: comparison with isoflurane and thiopental/halothane. Anesth Analg 1994; 79: 751-60
345. Annadata R, Sessler DI, Tayefeh F, et al. Desflurane slightly increases the sweating threshold but produces marked, non-linear decreases in the vasoconstriction and shivering thresholds. Anesthesiology 1995; 83: 1205-11
346. Kurz A, Xiong J, Sessler DI, et al. Desflurane reduces the gain of thermoregulatory arteriovenous shunt vasoconstriction in humans. Anesthesiology 1995; 83: 1212-9
347. Rampil IJ, Lockhart S, Eger EI II, et al. The electroencephalographic effects of desflurane in humans. Anesthesiology 1991; 74: 434-9
348. Hoffman WE, Edelman G. Comparison of isoflurane and desflurane anesthetic depth using burst suppression of the electroencephalogram in neurosurgical patients. Anesth Analg 1995; 81: 811-6
349. Kawaguchi M, Sakamoto T, Ohnishi H, et al. Intraoperative myogenic motor evoked potentials induced by direct electrical stimulation of the exposed motor cortex under isoflurane and sevoflurane. Anesth Analg 1996; 82: 593-9
350. Sloan T, Rogers J, Sloan G, et al. A comparison of the effects of isoflurane and desflurane on transcranial motor evoked potentials in the baboon [abstract]. Anesthesiology 1994; 81: A484
351. Lockhart SH, Rampil IJ, Yasuda N, et al. Depression of ventilation by desflurane in humans. Anesthesiology 1991; 74: 484-8
352. Daniel M, Larson MD, Eger EI II, et al. Modification by fentanyl and nitrous oxide on the effect of increases in desflurane and concentration on pupil size [abstract]. Anesthesiology 1994; 81: A384
353. Daniel M, Larson MD, Eger EI II, et al. Effect of fentanyl and desflurane on the human pupillary light reflex with constant pupil size [abstract]. Anesthesiology 1994; 81: A385
354. Jones RM, Koblin DD, Cashman JN, et al. Biotransformation and hepato-renal function in volunteers after exposure to desflurane (1653). Br J Anaesth 1990; 64: 482-7
355. Martin JL, Plevak DJ, Flannery KD, et al. Hepatotoxicity after desflurane anesthesia. Anesthesiology 1995; 83: 1125-9
356. Gan TJ, Quill TJ, Pressley C, et al. A comparison of mivacurium dosage requirements during isoflurane and desflurane anesthesia. J Clin Anesth 1996; 8: 301-6
357. Kumar N, Mirakhur RK, Symington MJ, et al. A comparison of the effects of isoflurane and desflurane on the neuromuscular effects of mivacurium. Anaesthesia 1996; 51: 547-50
358. Hart PS, Wright PMC, Lau M, et al. Neuromuseular recovery during washout of desflurane vs. isoflurane [abstract]. Anesthesiology 1994; 81: A1115
359. Wright PM, Hart P, Lau M, et al. The magnitude and time course of vecuronium potentiation by desflurane versus isoflurane. Anesthesiology 1995; 82: 404-11
360. Tuchy GL, Tuchy E, Bleyberg M, et al. Pharmacodynamics of mivacurium during desflurane anesthesia [abstract]. Anesthesiology 1994; 81: A1116
361. Abboud TK, Zhu J, Richardson M, et al. Desflurane: a new volatile aesthetic for cesarean section. Maternal and neonatal effects. Acta Anaesthesiol Scand 1995; 39: 723-6
362. Abboud TK, Swart F, Zhu J, et al. Desflurane analgesia for vaginal delivery. Acta Anaesthesiol Scand 1995; 39: 259-61
363. Wedel DJ, Gammel SA, Milde JH, et al. Delayed onset of malignant hyperthermia induced by isoflurane and desflurane compared with halothane in susceptible swine. Anesthesiology 1993; 78: 1138-44