Serotonin-independent model of cisplatin-induced emesis in the ferret

Japanese Journal of Pharmacology

Volumn 78, Issue 3, 1998, Pages 253-260

  Rudd, John A ^a   Cheng, Celine H K ^b   Naylor, Robert J ^b  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

Cisplatin; Delayed; Emesis; Ferret; p Chlorophenylalanine

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; CISPLATIN; DOPAMINE; FENCLONINE; HOMOVANILLIC ACID; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CONTROLLED STUDY; FERRET; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; URINE LEVEL; VOMITING;

EID: 0031789815     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.78.253     Document Type: Article

References (36)

1. Kris MG, Gralla RJ, Clark RA, Tyson LB, O'Connell JP, Wertheim MS and Kelsen DP: Incidence, course, and severity of delayed nausea and vomiting following the administration of high-dose cisplatin. J Clin Oncol 3, 1379-1384 (1985)
2. Martin M: The severity and pattern of emesis following different cytotoxic agents. Oncology 53, Suppl 1, 26-31 (1996)
3. Cubeddu LX, Hoffmann IS, Fuenmayor NT and Malave JJ: Changes in serotonin metabolism in cancer patients: its relationship to nausea and vomiting induced by chemotherapeutic drugs. Br J Cancer 66, 198-203 (1992)
4. Cubeddu LX and Hoffmann IS: Participation of serotonin on early and delayed emesis induced by initial and subsequent cycles of cisplatinum-based chemotherapy: effects of antiemetics. J Clin Pharmacol 33, 691-697 (1993)
5. Butcher ME: Global experience with ondansetron and future potential. Oncology 50, 191-197 (1993)
6. Alfieri AB and Cubeddu LX: Treatment with parachlorophenylalanine antagonises the emetic response and the serotonin-releasing actions of cisplatin in cancer patients. Br J Cancer 71, 629-632 (1995)
7. Gebbia V, Cannata G, Testa A, Curto G, Valenza R, Cipolla C, Latteri MA and Gebbia N: Ondansetron versus granisetron in the prevention of chemotherapy-induced nausea and vomiting. Results of a prospective randomized trial. Cancer 74, 1945-1952 (1994)
8. Chevallier B, Marty M and Paillarse JM: Methylprednisolone enhances the efficacy of ondansetron in acute and delayed cisplatin-induced emesis over at least three cycles. Ondansetron Study Group. Br J Cancer 70, 1171-1175 (1994)
9. Roila F, Tonato M and Del Favero A: Prevention of chemotherapy-induced emesis: the state of the art. Dig Dis 11, 343-353 (1993)
10. Naylor RJ and Rudd JA: Mechanisms of chemotherapy/ radiotherapy-induced emesis in animal models. Oncology 53, Suppl 1, 8-17 (1996)
11. Rudd JA, Bunce KT and Naylor RJ: The interaction of dexamethasone with ondansetron on drug-induced emesis in the ferret. Neuropharmacology 35, 91-97 (1996)
12. Rudd JA, Jordan CC and Naylor RJ: Profiles of emetic action of cisplatin in the ferret: a potential model of acute and delayed emesis. Eur J Pharmacol 262, R1-R2 (1994)
13. 3 receptor antagonists on models of acute and delayed emesis induced by cisplatin in the ferret. Neuropharmacology 33, 1607-1608 (1994)
14. Rudd JA and Naylor RJ: The actions of ondansetron and dexamethasone to antagonise cisplatin-induced emesis in the ferret. Eur J Pharmacol 322, 79-82 (1997)
15. Rudd JA, Jordan CC and Naylor RJ: The action of the NK, tachykinin receptor antagonist, CP 99,994, in antagonizing the acute and delayed emesis induced by cisplatin in the ferret. Br J Pharmacol 119, 931-936 (1996)
16. Barnes JM, Barnes NM, Costall B, Naylor RJ and Tattersall FD: Reserpine, para-chlorophenylalanine and fenfluramine antagonise cisplatin-induced emesis in the ferret. Neuropharmacology 27, 783-790 (1988)
17. Andrews PLR, Rapeport WG and Sanger GJ: Neuropharmacology of emesis induced by anti-cancer therapy. Trends Pharmacol Sci 9, 334-341 (1988)
18. 1 receptor, and potent broad-spectrum anti-emetic activity. Regul Pept 65, 45-53 (1996)
19. 1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatinin ferrets. Neuropharmacology 35, 1121-1129 (1996)
20. Koe K and Weissman A: p-Chlorophenylalanine: a specific depletor of brain serotonin. J Pharmacol Exp Ther 154, 499-516 (1966)
21. Weber LJ: p-Chlorophenylalanine-induced depletion of gastrointestinal 5-hydroxytryptamine. Biochem Pharmacol 19, 2169-2172 (1970)
22. 3 receptors mediate cisplatin-induced emesis in dogs. Jpn J Pharmacol 59, 221-226 (1992)
23. 3 receptor antagonists on cisplatin-induced emesis in the pigeon. Eur J Pharmacol 221, 343-350 (1992)
24. Fukui H, Yamamoto M, Ando T, Sasaki S and Sato S: Increase in serotonin levels in the dog ileum and blood by cisplatin as measured by microdialysis. Neuropharmacology 32, 959-968 (1993)
25. 3-receptor antagonist, GR38032F. Cancer Treat Rev 14, 333-336 (1987)
26. Minami M, Endo T, Nemoto M, Hamaue N, Hirafuji M, Monama Y, Yajima T, Yoshioka M and Saito H: How do toxic emetic stimuli cause 5-HT release in the gut and brain? In Serotonin and the Scientific Basis of Anti-emetic Therapy, Edited by Reynolds DJM, Andrews PLR and Davis CJ, pp 68-76, Oxford Clinical Communications, Oxford (1995)
27. Cubeddu LX, Hoffmann IS, Fuenmayor NT and Finn AL: Efficacy of ondansetron (GR 38032F) and the role of serotonin in cisplatin-induced nausea and vomiting. N Engl J Med 322, 810-816 (1990)
28. Nakajima Y, Yamamoto K, Yamada Y, Sawada Y and Iga T: Effect of cisplatin on the disposition of endogenous serotonin and its main metabolite, 5-hydroxyindole-3-acetic acid, in rats and dogs. Biol Pharm Bull 19, 318-322 (1996)
29. Cubeddu LX, O'Connor DT, Hoffmann I and Parmer RJ: Plasma chromogranin A marks emesis and serotonin release associated with dacarbazine and nitrogen mustard but not with cyclophosphamide-based chemotherapies. Br J Cancer 72, 1033-1038 (1995)
30. 3 receptor antagonists injected into the area postrema inhibit cisplatin-induced emesis in the ferret. Br J Pharmacol 97, 247-255 (1989)
31. Lucot JB and Crampton GH: Buspirone blocks cisplatin-induced emesis in cats. J Clin Pharmacol 27, 817-818 (1987)
32. 1A-receptor agonists in Suncus murinus. Jpn J Pharmacol 64, 109-114 (1994)
33. 1A receptors. Pathophysiology 1, 267-268 (1994)
34. Andrews PLR, Davis CJ, Bingham S, Davidson HIM, Hawthorn J and Maskell L: The abdominal visceral innervation and the emetic reflex: pathways, pharmacology, and plasticity. Can J Physiol Pharmacol 68, 325-345 (1990)
35. Milano S, Blower P, Romain D and Grelot L: The piglet as a suitable animal model for studying the delayed phase of cisplatin-induced emesis. J Pharmacol Exp Ther 274, 951-961 (1995)
36. Rudd JA and Naylor RJ: An interaction of ondansetron and dexamethasone antagonizing cisplatin-induced acute and delayed emesis in the ferret. Br J Pharmacol 118, 209-214 (1996)