-
1
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
2
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin D, Li FP, Strong LC, et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250:1233-1238, 1990.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
-
3
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors
-
Donehower LA, Harvey M, Slagle BL, et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature 356:215-221, 1992.
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
-
4
-
-
0027203921
-
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors
-
Kemp CJ, Donehower LA, Bradley A, Balmain A. Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors Cell 74:813-822, 1993.
-
(1993)
Cell
, vol.74
, pp. 813-822
-
-
Kemp, C.J.1
Donehower, L.A.2
Bradley, A.3
Balmain, A.4
-
5
-
-
0029782220
-
Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha
-
Greenhalgh DA, Wang XJ, Donehower LA, Roop DR. Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha. Cancer Res 56:4413-4423, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 4413-4423
-
-
Greenhalgh, D.A.1
Wang, X.J.2
Donehower, L.A.3
Roop, D.R.4
-
6
-
-
0028842340
-
A mutant p53 transgene accelerates tumor development in heterozygous but not nullizygous p53-deficient mice
-
Harvey M, Vogel H, Morris D, Bradley A, Bernstein A, Donehower LA. A mutant p53 transgene accelerates tumor development in heterozygous but not nullizygous p53-deficient mice. Nat Genet 9:305-311, 1995.
-
(1995)
Nat Genet
, vol.9
, pp. 305-311
-
-
Harvey, M.1
Vogel, H.2
Morris, D.3
Bradley, A.4
Bernstein, A.5
Donehower, L.A.6
-
7
-
-
0027210981
-
Gain of function mutations in p53
-
Dittmer D, Pati S, Zambetti G, et al. Gain of function mutations in p53. Nat Genet 4:42-46, 1993.
-
(1993)
Nat Genet
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pati, S.2
Zambetti, G.3
-
8
-
-
0025618980
-
Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: A comparison of the "hot spot" mutant phenotypes
-
Hinds PW, Finlay CA, Quartin RS, et al. Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: A comparison of the "hot spot" mutant phenotypes. Cell Growth Differ 1:571-580, 1990.
-
(1990)
Cell Growth Differ
, vol.1
, pp. 571-580
-
-
Hinds, P.W.1
Finlay, C.A.2
Quartin, R.S.3
-
9
-
-
0026510193
-
Oncogenic forms of p53 inhibit p53-regulated gene expression
-
Kern SE, Pietenpol JA, Thiagalingam S, Seymour A, Kinzler KW, Vogelstein B. Oncogenic forms of p53 inhibit p53-regulated gene expression. Science 256:827-830, 1992.
-
(1992)
Science
, vol.256
, pp. 827-830
-
-
Kern, S.E.1
Pietenpol, J.A.2
Thiagalingam, S.3
Seymour, A.4
Kinzler, K.W.5
Vogelstein, B.6
-
10
-
-
0027275854
-
Novel DNA binding of p53 mutants and their role in transcriptional activation
-
Zhang W, Funk WD, Wright WE, Shay JW, Deisseroth AB. Novel DNA binding of p53 mutants and their role in transcriptional activation. Oncogene 8:2555-2559, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 2555-2559
-
-
Zhang, W.1
Funk, W.D.2
Wright, W.E.3
Shay, J.W.4
Deisseroth, A.B.5
-
11
-
-
0027994037
-
Analysis of the most representative tumor-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation
-
Dry K, Legros Y, Auguin C, Soussi T. Analysis of the most representative tumor-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation. EMBO J 13:3496-3504, 1994.
-
(1994)
EMBO J
, vol.13
, pp. 3496-3504
-
-
Dry, K.1
Legros, Y.2
Auguin, C.3
Soussi, T.4
-
12
-
-
0032500106
-
Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis
-
Wang XJ, Greenhalgh DA, Jiang A, et al. Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene 17:35-45, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 35-45
-
-
Wang, X.J.1
Greenhalgh, D.A.2
Jiang, A.3
-
13
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86:353-364, 1996.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
14
-
-
0028060380
-
Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
-
Dameron KM, Volpert OV, Tainsky MA, Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 265:1582-1584, 1994.
-
(1994)
Science
, vol.265
, pp. 1582-1584
-
-
Dameron, K.M.1
Volpert, O.V.2
Tainsky, M.A.3
Bouck, N.4
-
15
-
-
0027958348
-
Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression
-
Kieser A, Weich HA, Brandner G, Marme D, Kolch W. Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene 9:963-969, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 963-969
-
-
Kieser, A.1
Weich, H.A.2
Brandner, G.3
Marme, D.4
Kolch, W.5
-
16
-
-
0028865988
-
Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression
-
Mukhopadhyay D, Tsiokas L, Sukhatme VP. Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression. Cancer Res 55:6161-6165, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 6161-6165
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Sukhatme, V.P.3
-
17
-
-
0030054914
-
Regulation of VEGF/VPF expression in tumor cells: Consequences for tumor growth and metastasis
-
Claffey KP, Robinson GS. Regulation of VEGF/VPF expression in tumor cells: Consequences for tumor growth and metastasis. Cancer Metastasis Rev 15:165-176, 1996.
-
(1996)
Cancer Metastasis Rev
, vol.15
, pp. 165-176
-
-
Claffey, K.P.1
Robinson, G.S.2
-
18
-
-
0028985020
-
TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas
-
Wang XJ, Greenhalgh DA, Lu XR, Bickenbach JR, Roop DR. TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas. Oncogene 10:279-289, 1995.
-
(1995)
Oncogene
, vol.10
, pp. 279-289
-
-
Wang, X.J.1
Greenhalgh, D.A.2
Lu, X.R.3
Bickenbach, J.R.4
Roop, D.R.5
-
19
-
-
0028332305
-
Epidermal expression of transforming growth factor-alpha in transgenic mice: Induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression
-
Wang XJ, Greenhalgh DA, Eckhardt JN, Rothnagel JA, Roop DR. Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression. Mol Carcinog 10:15-22, 1994.
-
(1994)
Mol Carcinog
, vol.10
, pp. 15-22
-
-
Wang, X.J.1
Greenhalgh, D.A.2
Eckhardt, J.N.3
Rothnagel, J.A.4
Roop, D.R.5
-
20
-
-
0029881977
-
Abnormal centrosome amplification in the absence of p53
-
Fukasawa K, Choi T, Kuriyama R, Rulong S, Vande Woude G. Abnormal centrosome amplification in the absence of p53. Science 271:1744-1747, 1996.
-
(1996)
Science
, vol.271
, pp. 1744-1747
-
-
Fukasawa, K.1
Choi, T.2
Kuriyama, R.3
Rulong, S.4
Vande Woude, G.5
-
21
-
-
0031035639
-
Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability
-
Fukasawa K, Vande Woude G. Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability. Mol Cell Biol 17:506-518, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 506-518
-
-
Fukasawa, K.1
Vande Woude, G.2
-
22
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
-
Kaghad M, Bonnet H, Yang A, et al. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90:809-819, 1997.
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
-
23
-
-
0031564954
-
p73 is a human p53-related protein that can induce apoptosis
-
Jost CA, Marin MC, Kaelin WG Jr. p73 is a human p53-related protein that can induce apoptosis. Nature 389:191-194, 1997.
-
(1997)
Nature
, vol.389
, pp. 191-194
-
-
Jost, C.A.1
Marin, M.C.2
Kaelin Jr., W.G.3
-
24
-
-
0026660339
-
Properties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens
-
Crook T, Vousden KH. Properties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens. EMBO J 11:3935-3940, 1992.
-
(1992)
EMBO J
, vol.11
, pp. 3935-3940
-
-
Crook, T.1
Vousden, K.H.2
|