메뉴 건너뛰기




Volumn 23, Issue 3, 1998, Pages 185-192

Analysis of centrosome abnormalities and angiogenesis in epidermal- targeted p53(172H) mutant and p53-knockout mice after chemical carcinogenesis: Evidence for a gain of function

Author keywords

Angiogenesis; Centrosome; Gain of function; Human keratin 1; P53

Indexed keywords

KERATIN; PROTEIN P53; THROMBOSPONDIN 1;

EID: 0031789426     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199811)23:3<185::AID-MC7>3.0.CO;2-5     Document Type: Conference Paper
Times cited : (52)

References (24)
  • 1
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878, 1994.
    • (1994) Cancer Res , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 2
    • 0025633582 scopus 로고
    • Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
    • Malkin D, Li FP, Strong LC, et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250:1233-1238, 1990.
    • (1990) Science , vol.250 , pp. 1233-1238
    • Malkin, D.1    Li, F.P.2    Strong, L.C.3
  • 3
    • 0026561121 scopus 로고
    • Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors
    • Donehower LA, Harvey M, Slagle BL, et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature 356:215-221, 1992.
    • (1992) Nature , vol.356 , pp. 215-221
    • Donehower, L.A.1    Harvey, M.2    Slagle, B.L.3
  • 4
    • 0027203921 scopus 로고
    • Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors
    • Kemp CJ, Donehower LA, Bradley A, Balmain A. Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors Cell 74:813-822, 1993.
    • (1993) Cell , vol.74 , pp. 813-822
    • Kemp, C.J.1    Donehower, L.A.2    Bradley, A.3    Balmain, A.4
  • 5
    • 0029782220 scopus 로고    scopus 로고
    • Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha
    • Greenhalgh DA, Wang XJ, Donehower LA, Roop DR. Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha. Cancer Res 56:4413-4423, 1996.
    • (1996) Cancer Res , vol.56 , pp. 4413-4423
    • Greenhalgh, D.A.1    Wang, X.J.2    Donehower, L.A.3    Roop, D.R.4
  • 6
    • 0028842340 scopus 로고
    • A mutant p53 transgene accelerates tumor development in heterozygous but not nullizygous p53-deficient mice
    • Harvey M, Vogel H, Morris D, Bradley A, Bernstein A, Donehower LA. A mutant p53 transgene accelerates tumor development in heterozygous but not nullizygous p53-deficient mice. Nat Genet 9:305-311, 1995.
    • (1995) Nat Genet , vol.9 , pp. 305-311
    • Harvey, M.1    Vogel, H.2    Morris, D.3    Bradley, A.4    Bernstein, A.5    Donehower, L.A.6
  • 7
    • 0027210981 scopus 로고
    • Gain of function mutations in p53
    • Dittmer D, Pati S, Zambetti G, et al. Gain of function mutations in p53. Nat Genet 4:42-46, 1993.
    • (1993) Nat Genet , vol.4 , pp. 42-46
    • Dittmer, D.1    Pati, S.2    Zambetti, G.3
  • 8
    • 0025618980 scopus 로고
    • Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: A comparison of the "hot spot" mutant phenotypes
    • Hinds PW, Finlay CA, Quartin RS, et al. Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: A comparison of the "hot spot" mutant phenotypes. Cell Growth Differ 1:571-580, 1990.
    • (1990) Cell Growth Differ , vol.1 , pp. 571-580
    • Hinds, P.W.1    Finlay, C.A.2    Quartin, R.S.3
  • 10
    • 0027275854 scopus 로고
    • Novel DNA binding of p53 mutants and their role in transcriptional activation
    • Zhang W, Funk WD, Wright WE, Shay JW, Deisseroth AB. Novel DNA binding of p53 mutants and their role in transcriptional activation. Oncogene 8:2555-2559, 1993.
    • (1993) Oncogene , vol.8 , pp. 2555-2559
    • Zhang, W.1    Funk, W.D.2    Wright, W.E.3    Shay, J.W.4    Deisseroth, A.B.5
  • 11
    • 0027994037 scopus 로고
    • Analysis of the most representative tumor-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation
    • Dry K, Legros Y, Auguin C, Soussi T. Analysis of the most representative tumor-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation. EMBO J 13:3496-3504, 1994.
    • (1994) EMBO J , vol.13 , pp. 3496-3504
    • Dry, K.1    Legros, Y.2    Auguin, C.3    Soussi, T.4
  • 12
    • 0032500106 scopus 로고    scopus 로고
    • Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis
    • Wang XJ, Greenhalgh DA, Jiang A, et al. Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene 17:35-45, 1998.
    • (1998) Oncogene , vol.17 , pp. 35-45
    • Wang, X.J.1    Greenhalgh, D.A.2    Jiang, A.3
  • 13
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86:353-364, 1996.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 14
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • Dameron KM, Volpert OV, Tainsky MA, Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 265:1582-1584, 1994.
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 15
    • 0027958348 scopus 로고
    • Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression
    • Kieser A, Weich HA, Brandner G, Marme D, Kolch W. Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene 9:963-969, 1994.
    • (1994) Oncogene , vol.9 , pp. 963-969
    • Kieser, A.1    Weich, H.A.2    Brandner, G.3    Marme, D.4    Kolch, W.5
  • 16
    • 0028865988 scopus 로고
    • Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression
    • Mukhopadhyay D, Tsiokas L, Sukhatme VP. Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression. Cancer Res 55:6161-6165, 1995.
    • (1995) Cancer Res , vol.55 , pp. 6161-6165
    • Mukhopadhyay, D.1    Tsiokas, L.2    Sukhatme, V.P.3
  • 17
    • 0030054914 scopus 로고    scopus 로고
    • Regulation of VEGF/VPF expression in tumor cells: Consequences for tumor growth and metastasis
    • Claffey KP, Robinson GS. Regulation of VEGF/VPF expression in tumor cells: Consequences for tumor growth and metastasis. Cancer Metastasis Rev 15:165-176, 1996.
    • (1996) Cancer Metastasis Rev , vol.15 , pp. 165-176
    • Claffey, K.P.1    Robinson, G.S.2
  • 18
    • 0028985020 scopus 로고
    • TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas
    • Wang XJ, Greenhalgh DA, Lu XR, Bickenbach JR, Roop DR. TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas. Oncogene 10:279-289, 1995.
    • (1995) Oncogene , vol.10 , pp. 279-289
    • Wang, X.J.1    Greenhalgh, D.A.2    Lu, X.R.3    Bickenbach, J.R.4    Roop, D.R.5
  • 19
    • 0028332305 scopus 로고
    • Epidermal expression of transforming growth factor-alpha in transgenic mice: Induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression
    • Wang XJ, Greenhalgh DA, Eckhardt JN, Rothnagel JA, Roop DR. Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression. Mol Carcinog 10:15-22, 1994.
    • (1994) Mol Carcinog , vol.10 , pp. 15-22
    • Wang, X.J.1    Greenhalgh, D.A.2    Eckhardt, J.N.3    Rothnagel, J.A.4    Roop, D.R.5
  • 21
    • 0031035639 scopus 로고    scopus 로고
    • Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability
    • Fukasawa K, Vande Woude G. Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability. Mol Cell Biol 17:506-518, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 506-518
    • Fukasawa, K.1    Vande Woude, G.2
  • 22
    • 0030812331 scopus 로고    scopus 로고
    • Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
    • Kaghad M, Bonnet H, Yang A, et al. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90:809-819, 1997.
    • (1997) Cell , vol.90 , pp. 809-819
    • Kaghad, M.1    Bonnet, H.2    Yang, A.3
  • 23
    • 0031564954 scopus 로고    scopus 로고
    • p73 is a human p53-related protein that can induce apoptosis
    • Jost CA, Marin MC, Kaelin WG Jr. p73 is a human p53-related protein that can induce apoptosis. Nature 389:191-194, 1997.
    • (1997) Nature , vol.389 , pp. 191-194
    • Jost, C.A.1    Marin, M.C.2    Kaelin Jr., W.G.3
  • 24
    • 0026660339 scopus 로고
    • Properties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens
    • Crook T, Vousden KH. Properties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens. EMBO J 11:3935-3940, 1992.
    • (1992) EMBO J , vol.11 , pp. 3935-3940
    • Crook, T.1    Vousden, K.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.