Characterization of mouse retinoid X receptor (RXR)-β gene promoter: Negative regulation by tumor necrosis factor (TNF)-α

Endocrinology

Volumn 139, Issue 6, 1998, Pages 3030-3033

  Sugawara, Akira ^a   Uruno, Akira ^a   Nagata, Toshi ^b   Taketo, Makoto M ^c   Takeuchi, Kazuhisa ^a   Ito, Sadayoshi ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALITRETINOIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; RETINOID X RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE ISOLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION;

EID: 0031789309     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.6.6130     Document Type: Article

References (24)

1. Mangelsdorf DJ, Borgmeyer U, Heyman RA, Zhou JY, Ong ES, Oro AE, Kakizuka A, Evans RM 1992 Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev 6: 329-344
2. Yu VC, Delsert C, Andersen B, Holloway JM, Devary OV, Naar AM, Kim SY, Boutin J-M, Glass CK, Rosenfeld MG 1991 RXRβ: acoregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell 67: 1251-1266
3. Kliewer SA, Umesono K, Noonan DJ, Heyman RA, Evans RM 1992 Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathway through heterodimer formation of their receptors. Nature 358: 771-774
4. 3) receptor-auxiliary proteins (TRAPs), and their relationship to the retinoid X receptors (RXRs). Endocrinology 133: 965-971
5. Sugawara A, Sanno N, Takahashi N, Osamura RY, Abe K 1997 Retinoid X receptors (RXRs) in the kidney: their protein expression and functional significance. Endocrinology 138: 3175-3180
6. Sugawara A, Yen PM, Qi Y, Lechan RM, Chin WW 1995 Isoform-specific retinoid-X receptor (RXR) antibodies detect differential expression of RXR proteins in the pituitary gland. Endocrinology 136: 1766-1774
7. Sugawara A, Yen PM, Chin WW 1994 9-cis retinoic acid regulation of rat growth hormone gene expression: potential roles of multiple nuclear hormone receptors. Endocrinology 135: 1956-1962
8. Hamada K, Gleason SL, Levi B-Z, Hirschfeld S , Appella E, Ozato K 1989 H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory elementof major histocompatibility class I genes and the estrogen response element. Proc Natl Acad Sci USA 86: 8289-8293
9. Nagata T, Segars JH, Levi B-Z, Ozato K 1992 Retinoic acid-dependent transactivation of major histocompatibility complex class I promoters by the nuclear hormone receptor H-2RIIBP in undifferentiated embryonal carcinoma cells. Proc Natl Acad Sci USA 89: 937-941
10. Nagata T, Kanno Y, Ozato K, Taketo M 1994 The mouse Rxrb gene encoding RXRβ: genomic organization and two mRNA isoforms generated by alternative splicing of transcripts initiated from CpG island promoters. Gene 142: 183-189
11. Nagata T, Weiss EH, Abe K, Kitagawa K, Ando A, Yara-Kikuti Y, Seldin MF, Ozato K, Inoko H, Taketo M 1995 Physical mapping of the retinoid X receptor B gene in mouse and human. Immunogenetics 41: 83-90
12. w5 region of mice. Mol Cell Biol 10: 138-145
13. Willheim M, Silacci P, Gessl A, Spittler A, Szepfalusi Z, Samorapoompichit P, Agis H, Mayr WR, Scheiner O, Forster O, Mach B, Boltz-Nitulescu G 1994 Tumor necrosis factor-α induction of major histocompatibility complex class II antigen expression is inhibited by interferon-γ in a monocytic cell line. Eur J Immunol 25: 3202-3206
14. Nordeen S K 1988 Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6: 454-458
15. Verma IM, Stevenson JK, Schwarz EM, Antwerp DV, Miyamoto S 1995 Rel/NF-κB/κB family: intimate tales of association and dissociation. Genes Dev 9: 2723-2735
16. Wang XZ, Ron D 1996 Stress-inducedphosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase. Science 272: 1347-1349
17. Han J, Lee J-D, Bibbs L, Ulevitch RJ 1994 A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265: 808-811
18. Dunnett CW 1970 Multiple comparisons. In: McArthur JW, Colton T (eds) Statistics in Endocrinology. MIT Press, Cambridge, MA, p. 84
19. Mano H, Mori R, Ozawa T, Takeyama K, Yoshizawa Y, Kojima R, Arao Y, Masushige S , Kato S 1994 Positive and negative regulation of retinoid X receptor gene expression by thyroid hormone in the rat. J Biol Chem 269: 1591-1594
20. Pietersma A, Tilly BC, Gaestel M, de Jong N, Lee JC, Koster JF, Sluiter W 1997 p38 mitogen activated protein kinase regulates endothelial VCAM-1 expression at the post-transcriptional level. Biochem Biophys Res Commun 230: 44-48
21. Totpal K, Chaturvedi MM, LaPushin R, Aggarwal BB 1995 Retinoids downregulate both p60 and p80 forms of tumor necrosis factor receptors in human histiocytic lymphoma U-937 cells. Blood 85: 3547-3555
22. Mehta K, McQueen T, Tucker S, Pandita R, Aggarwal BB 1994 Inhibition by all-trans-retinoic acid of tumor necrosis factor and nitric oxide production by peritoneal macrophages. J Leukoc Biol 55: 336-342
23. Blake JA, Richardson JE, Davisson MT, Eppig JT 1997 The Mouse Genome Database (MGD). A comprehensive public resource of genetic, phenotypic and genomic data. The Mouse Genome Informatics Group. Nucleic Acids Res 25: 85-91
24. Zhang B, Berger J, Hu E, Szalkowski D, White-Carrington S, Spiegelman BM, Moller DE 1996 Negative regulation of peroxisome proliferator-activated receptor-γ gene expression contributes to the antiadipogenic effects of tumor necrosis factor-α. Mol Endocrinol 10: 1457-1466