The evolutionarily conserved eukaryotic arginine attenuator peptide regulates the movement of ribosomes that have translated it

Molecular and Cellular Biology

Volumn 18, Issue 12, 1998, Pages 7528-7536

  Wang, Zhong ^a   Fang, Peng ^a   Sachs, Matthew S ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE;

AMINO ACID SEQUENCE; ARTICLE; GENE EXPRESSION; NEUROSPORA CRASSA; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; RNA TRANSLATION; SEQUENCE ANALYSIS; START CODON; STOP CODON; TRANSLATION INITIATION; TRANSLATION REGULATION;

EUKARYOTA; NEUROSPORA CRASSA;

EID: 0031785415     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.12.7528     Document Type: Article

References (27)

1. Baek, J.-M., and C. M. Kenerley. 1998. The arg2 gene of Trichoderma virens: cloning and development of a homologous transformation system. Fungal Genet. Biol. 23:34-44.
2. Cao, J., and A. P. Geballe. 1998. Ribosomal release without peptidyl tRNA hydrolysis at translation termination in a eukaryotic system. RNA 4:181-188.
3. Crabeel, M., R. LaValle, and N. Glansdorff. 1990. Arginine-specific repression in Saccharomyces cerevisiae: kinetic data on ARG1 and ARG3 mRNA transcription and stability support a transcriptional control mechanism. Mol. Cell. Biol. 10:1226-1233.
4. Davis, R. H. 1986. Compartmental and regulatory mechanisms in the arginine pathways of Neurospora crassa and Saccharomyces cerevisiae. Microbiol. Rev. 50:280-313.
5. Delbecq, P., M. Werner, A. Feller, R. K. Filipkowski, F. Messenguy, and A. Piérard. 1994. A segment of mRNA encoding the leader peptide of the CPA1 gene confers repression by arginine on a heterologous yeast gene transcript. Mol. Cell. Biol. 14:2378-2390.
6. Edelmann, S. E., and C. Staben. 1994. A statistical analysis of sequence features within genes from Neurospora crassa. Exp. Mycol. 18:70-81.
7. Farabaugh, P. J. 1996. Programmed translational frameshifting. Microbiol. Rev. 60:103-134.
8. Federov, A. N., and T. O. Baldwin. 1998. Protein folding and assembly in a cell-free expression system. Methods Enzymol. 290:1-17.
9. Freitag, M., N. Dighde, and M. S. Sachs. 1996. A UV-induced mutation that affects translational regulation of the Neurospora arg-2 gene. Genetics 142: 117-127.
10. Hinnebusch, A. G. 1997. Translational regulation of yeast GCN4: a window on factors that control initiator-tRNA binding to the ribosome. J. Biol. Chem. 272:21661-21664.
11. Képès, F. 1996. The "+70 pause": hypothesis of a translational control of membrane protein assembly. J. Mol. Biol. 262:77-86.
12. Koloteva, N., P. P. Muller, and J. E. McCarthy. 1997. The position dependence of translational regulation via RNA-RNA and RNA-protein interactions in the 5′-untranslated region of eukaryotic mRNA is a function of the thermodynamic competence of 40 S ribosomes in translational initiation. J. Biol. Chem. 272:16531-16539.
13. Komar, A. A., and R. Jaenicke. 1995. Kinetics of translation of γ B crystallin and its circularly permutated variant in an in vitro cell-free system: possible relations to codon distribution and protein folding. FEBS Lett. 376:195-198.
14. Landick, R., C. L. J. Turnbough, and C. Yanofsky. 1996. Transcription attenuation, p. 1263-1286. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Maasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology, vol. 1. ASM Press, Washington, D.C.
15. Larsen, B., J. Peden, S. Matsufuji, T. Matsufuji, K. Brady, R. Maldonado, N. M. Wills, O. Fayet, J. F. Atkins, and R. F. Gesteland. 1995. Upstream stimulators for recoding. Biochem. Cell Biol. 73:1123-1129.
16. Liao, S., J. Lin, H. Do, and A. E. Johnson. 1997. Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration. Cell 90:31-41.
17. Lovett, P. S., and E. J. Rogers. 1996. Ribosome regulation by the nascent peptide. Microbiol. Rev. 60:366-385.
18. Luo, Z., M. Freitag, and M. S. Sachs. 1995. Translational regulation in response to changes in amino acid availability in Neurospora crassa. Mol. Cell. Biol. 15:5235-5245.
19. Luo, Z., and M. S. Sachs. 1996. Role of an upstream open reading frame in mediating arginine-specific translational control in Neurospora crassa. J. Bacteriol. 178:2172-2177.
20. Orbach, M. J., M. S. Sachs, and C. Yanofsky. 1990. The Neurospora crassa arg-2 locus: structure and expression of the gene encoding the small subunit of arginine-specific carbamoyl phosphate synthetase. J. Biol. Chem. 265: 10981-10987.
21. Shen, W.-C., and D. J. Ebbole. 1997. Cross-pathway and pathway-specific control of amino acid biosynthesis in Magnaporthe grisea. Fungal Genet. Biol. 21:40-49.
22. Srb, A. M., and N. H. Horowitz. 1944. The ornithine cycle in Neurospora and its genetic control. J. Biol. Chem. 154:129-139.
23. Thanaraj, T. A., and P. Argos. 1996. Ribosome-mediated translational pause and protein domain organization. Protein Sci. 5:1594-1612.
24. Walter, P., and A. E. Johnson. 1994. Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Annu. Rev. Cell. Biol. 10: 87-119.
25. Wang, Z., and M. S. Sachs. 1997. Arginine-specific regulation mediated by the Neurospora crassa arg-2 upstream open reading frame in a homologous, cell-free in vitro translation system. J. Biol. Chem. 272:255-261.
26. Wang, Z., and M. S. Sachs. 1997. Ribosome stalling is responsible for arginine-specific translational attenuation in Neurospora crassa. Mol. Cell. Biol. 17:4904-4913.
27. Werner, M., A. Feller, F. Messenguy, and A. Piérard. 1987. The leader peptide of yeast CPA1 is essential for the translational repression of its expression. Cell 49:805-813.