The anticonvulsant lamotrigine in treatment-resistant manic-depressive illness

Journal of Clinical Psychopharmacology

Volumn 17, Issue 3, 1997, Pages 185-189

  Sporn, Jonathan ^a   Sachs, Gary ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; AMITRIPTYLINE; ANTICONVULSIVE AGENT; ANXIOLYTIC AGENT; CARBAMAZEPINE; CHOLINE; CLONAZEPAM; HYPNOTIC AGENT; LAMOTRIGINE; LEVOTHYROXINE; LITHIUM; NEFAZODONE; NEUROLEPTIC AGENT; RISPERIDONE; SERTRALINE; TRIFLUOPERAZINE; VALPROIC ACID;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; FAMILY HISTORY; FEMALE; HUMAN; MANIC DEPRESSIVE PSYCHOSIS; MEDICAL RECORD; PANIC; PRIORITY JOURNAL; PSYCHIATRIC DIAGNOSIS; RATING SCALE;

ADULT; ANTICONVULSANTS; ANXIETY; BIPOLAR DISORDER; DRUG RESISTANCE; FEMALE; HUMANS; MALE; MIDDLE AGED; TRIAZINES;

EID: 0030910672     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004714-199706000-00008     Document Type: Article

References (30)

1. Matsuo F, Bergen D, Faught E, Messenheimer JA, Dren AT, Rudd GD, Lineberry CG. Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures. U.S. Lamotrigine Protocol 0.5 Clinical Trial Group. Neurology 1993;43: 2284-91.
2. Messenheimer J, Ramsay RE, Willmore LJ, Leroy RF, Zielinski JJ, Mattson R, Pellock JM, Valakas AM, Womble G, Risner M. Lamotrigine therapy for partial seizures: a multicenter, placebo-controlled, double-blind, cross-over trial. Epilepsia 1994;35: 113-21.
3. Richens A. Safety of lamotrigine. [review]. Epilepsia 1994;35: S37-40.
4. Smith D, Chadwick D, Baker G, Davis G, Dewey M. Seizure severity and the quality of life. Epilepsia 1993;34:S31-5.
5. Smith D, Baker G, Davies G, Dewey M, Chadwick DW. Outcomes of add-on treatment with lamotrigine in partial epilepsy. Epilepsia 1993;34:312-22.
6. Weisler R, Risner M, Houser T. Use of lamotrigine in the treatment of bipolar disorder. American Psychiatry Association Meeting, Philadelphia, PA, May 21-26, 1994.
7. Calabrese JR, Bowden CL, Rhodes LJ, McElroy SL, Cookson J, Anderson J, Woyshville MJ, Keck PE, Kundu K, Ascher JA, Paterson G, Tvarno K, Bolden-Watson C. Lamotrigine in treatment-refractory bipolar disorder. American Psychiatric Association Annual Meeting, New York, May 4-9, 1996.
8. Calabrese J, Fatemi S, Woyshville M. Antidepressants effects of lamotrigine in rapid cycling bipolar disorder [letter]. Am J Psychiatry 1996;153:1236.
9. Burstein AH. Lamotrigine. [review]. Pharmacotherapy 1995;15: 129-43.
10. Dalby MA. Behavioral effects of carbamazepine. In: Penry JK, Daly DD, eds. Complex partial seizures and their treatment, vol. 11. New York: Raven Press, 1975.
11. Paul IA, Nowak G, Layer RT, Popik P, Skolnick P. Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments. J Pharmacol Exp Ther 1994;269:95-102.
12. Nowak G, Trullas R, Layer RT, Skolnick P, Paul IA. Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid. J Pharmacol Exp Ther 1993;265:1380-6.
13. 2+ antagonists effect an antidepressant-like adaptation of the NMDA receptor complex. Eur J Pharmacol 1993;247:101-2.
14. Trullas R, Folio T, Young A, Miller R, Boje K, Skolnick P. 1-aminocyclopropanecarboxylates exhibit antidepressant and anxiolytic actions in animal models. Eur J Pharmacol 1991;203: 379-85.
15. Papp M, Moryl E. Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression. Eur J Pharmacol 1994;263:1-7.
16. Paul IA, Trullas R, Skolnick P, Nowak G. Down-regulation of cortical beta-adrenoceptors by chronic treatment with functional NMDA antagonists. Psychopharmacology 1992;106:285-7.
17. Nowak G, Ordway GA, Paul IA. Alterations in the N-methyl-D-aspartate (NMDA) receptor complex in the frontal cortex of suicide victims. Brain Res 1995;675:157-64.
18. Leach MJ, Baxter MG, Critchley MA. Neurochemical and behavioral aspects of lamotrigine. [review]. Epilepsia 1991;32:S4-8.
19. Zipp F, Baas H, Fischer PA. Lamotrigine - antiparkinsonian activity by blockade of glutamate release? J Neural Transm Park Dis Dement Sect 1993;5:67-75.
20. Svensson A, Carlsson ML. Injection of the competitive NMDA receptor antagonist AP-5 into the nucleus accumbens of mono-amine-depleted mice induces pronounced locomotor stimulation. Neuropharmacology 1992;31:513-8.
21. Brodie MJ, Richens A, Yuen AW. Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. UK Lamotrigine/Carbamazepine Monotherapy Trial Group, [published erratum appears in Lancet 1995;345(8950):662] [see comments]. Lancet 1995;345:476-9.
22. Meador KJ, Loring DW, Moore BA, Thompson WO, Nichols ME, Oberzan BA, Durkin MD, Gallagher BB, King DW. Comparative cognitive effects of phenobarbital, phenytoin, and valproate in healthy adults. Neurology 1995;45:1494-99.
23. Hamilton MJ, Cohen AF, Yuen AW, Harkin NLG, Weatherley BC, Peck AW. Carbamazepine and lamotrigine in healthy volunteers: relevance to early tolerance and clinical trial dosage. Epilepsia 1993;34:166-73.
24. Patsalos PN, Duncan JS. Antiepileptic drugs. A review of clinically significant drug interactions. [review]. Drug Saf 1993;9: 156-84.
25. Patsalos PN, Sander JW. Newer antiepileptic drugs. Towards an improved risk-benefit ratio, [review] Drug Saf 1994;11:37-67.
26. Altshuler LL, Cohen L, Szuba MP, Burt VK, Gitlin M, Mintz J. Pharmacologic management of psychiatric illness during pregnancy: dilemmas and guidelines. Am J Psychiatry 1996;153:592-606.
27. Glaxo-Wellcome. International lamotrigine pregnancy registry interim report. Research Triangle Park, NC: Glaxo-Wellcome, 1995.
28. Leppik IE. Antiepileptic drugs in development: prospects for the near future, [review]. Epilepsia 1994;35:S29-40.
29. Blumer D, Montouris G, Hermann B. Psychiatric morbidity in seizure patients on a neurodiagnostic monitoring unit. J Neuropsychiatry Clin Neurosci 1995;7:445-6.
30. Silberman EK, Post RM, Nurnberger J. Transient sensory, cognitive and affective phenomena in affective illness: a comparison with complex partial epilepsy. Br J Psychiatry 1985;146:81-9.