Molecular and Cellular Pharmacology of a Calcium/ Calmodulin-Dependent Protein Kinase II (CaM Kinase II) Inhibitor, KN-62, and Proposal of CaM Kinase Phosphorylation Cascades

Advances in Pharmacology

Volumn 36, Issue C, 1996, Pages 193-219

  Hidaka, Hiroyoshi ^a   Yokokura, Hisayuki ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; CALMODULIN; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; DOPA; DRUG DERIVATIVE; ENZYME INHIBITOR; MYOSIN LIGHT CHAIN; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE INHIBITOR; SULFONAMIDE; TYROSINE 3 MONOOXYGENASE;

AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CARDIOVASCULAR SYSTEM; CHEMICAL STRUCTURE; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; MOLECULAR GENETICS; NERVE CELL; NUCLEOTIDE SEQUENCE; PANCREAS; PANCREAS ISLET; PHOSPHORYLATION; PHYSIOLOGY; REVIEW; SECRETION; SMOOTH MUSCLE; STRUCTURE ACTIVITY RELATION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALMODULIN; CARDIOVASCULAR SYSTEM; DIHYDROXYPHENYLALANINE; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; ISLETS OF LANGERHANS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUSCLE, SMOOTH; MYOSIN LIGHT CHAINS; NEURONS; PANCREAS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; TYROSINE 3-MONOOXYGENASE;

EID: 0030348282     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(08)60583-9     Document Type: Article

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