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Volumn 15, Issue 5, 1998, Pages 751-754

Influence of indocyanine green on plasma disappearance and biliary excretion of a synthetic thrombin inhibitor of the 3-amidinophenylalanine piperazide-type in rats

Author keywords

Bile; Indocyanine green; Plasma; Rats; Thrombin inhibitor

Indexed keywords

ICG PULSION; INDOCYANINE GREEN; NALPHA (2 NAPHTHYLSULFONYL) 3 AMIDINOPHENYLALANINE CARBOXYMETHYLPIPERAZIDE; PEFA 1023; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 0031779869     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011927204847     Document Type: Article
Times cited : (8)

References (19)
  • 1
    • 0026763390 scopus 로고
    • Pharmacologic aspects of the development of selective synthetic thrombin inhibitors as anticoagulants
    • J. Hauptmann and F. Markwardt. Pharmacologic aspects of the development of selective synthetic thrombin inhibitors as anticoagulants. Semin. Thrombos. Hemostas. 18:200-217 (1992).
    • (1992) Semin. Thrombos. Hemostas. , vol.18 , pp. 200-217
    • Hauptmann, J.1    Markwardt, F.2
  • 2
    • 0029147936 scopus 로고
    • Challenges in the development of orally bioavailable thrombin active site inhibitors
    • S. D. Kimball. Challenges in the development of orally bioavailable thrombin active site inhibitors. Blood Coag. & Fibrinol. 6:511-519 (1995).
    • (1995) Blood Coag. & Fibrinol. , vol.6 , pp. 511-519
    • Kimball, S.D.1
  • 3
    • 0020001329 scopus 로고
    • Tierexperimentelle Untersuchungen zur Pharmakokinetik von Nα-Tosyl-3-amidino-phenylalaninpiperidid (TAPAP), einem neuen Thrombininhibitor
    • J. Hauptmann, F. Markwardt, and M. Richter. Tierexperimentelle Untersuchungen zur Pharmakokinetik von Nα-Tosyl-3-amidino-phenylalaninpiperidid (TAPAP), einem neuen Thrombininhibitor. Pharmazie 37:430-433 (1982).
    • (1982) Pharmazie , vol.37 , pp. 430-433
    • Hauptmann, J.1    Markwardt, F.2    Richter, M.3
  • 4
    • 0022342897 scopus 로고
    • Pharmacological characterization of a new highly effective synthetic thrombin inhibitor
    • B. Kaiser, J. Hauptmann, A. Weiss, and F. Markwardt. Pharmacological characterization of a new highly effective synthetic thrombin inhibitor. Biomed. Biochim. Acta 44:1201-1210 (1985).
    • (1985) Biomed. Biochim. Acta , vol.44 , pp. 1201-1210
    • Kaiser, B.1    Hauptmann, J.2    Weiss, A.3    Markwardt, F.4
  • 5
    • 0023251851 scopus 로고
    • Biliary excretion of synthetic benzamidine-type thrombin inhibitors in rabbits and rats
    • J. Hauptmann, B. Kaiser, M. Paintz, and F. Markwardt. Biliary excretion of synthetic benzamidine-type thrombin inhibitors in rabbits and rats. Biomed. Biochim. Acta 46:445-453 (1987).
    • (1987) Biomed. Biochim. Acta , vol.46 , pp. 445-453
    • Hauptmann, J.1    Kaiser, B.2    Paintz, M.3    Markwardt, F.4
  • 6
    • 0026347092 scopus 로고
    • Argatroban, a selective, potent thrombin inhibitor
    • L. R. Bush. Argatroban, a selective, potent thrombin inhibitor. Cardiovasc. Drug Rev. 9:247-263 (1991).
    • (1991) Cardiovasc. Drug Rev. , vol.9 , pp. 247-263
    • Bush, L.R.1
  • 8
    • 0030881987 scopus 로고    scopus 로고
    • An exploratory trial of two dosages of a novel synthetic thrombin inhibitor (Napsagatran, Ro 46-6240) compared with unfractionated heparin for treatment of proximal deep-vein thrombosis. Results of the European multicenter ADVENT trial
    • H. Bounameaux, H. Ehringer, J. Hulting, H. Rasche, H. J. Rapold, and M. Zultak, and the ADVENT investigators. An exploratory trial of two dosages of a novel synthetic thrombin inhibitor (Napsagatran, Ro 46-6240) compared with unfractionated heparin for treatment of proximal deep-vein thrombosis. Results of the European multicenter ADVENT trial. Thromb. Haemost. 78:997-1002 (1997).
    • (1997) Thromb. Haemost. , vol.78 , pp. 997-1002
    • Bounameaux, H.1    Ehringer, H.2    Hulting, J.3    Rasche, H.4    Rapold, H.J.5    Zultak, M.6
  • 9
    • 0026020801 scopus 로고
    • In vitro and in vivo comparison of arginine- and benzamidine-derived highly potent synthetic thrombin inhibitors
    • J. Hauptmann and B. Kaiser. In vitro and in vivo comparison of arginine- and benzamidine-derived highly potent synthetic thrombin inhibitors. Pharmazie 46:57-58 (1991).
    • (1991) Pharmazie , vol.46 , pp. 57-58
    • Hauptmann, J.1    Kaiser, B.2
  • 10
    • 0029891673 scopus 로고    scopus 로고
    • First-pass elimination of a peptidomimetic thrombin inhibitor is due to carrier-mediated uptake by the liver
    • U. Eckhardt, W. Stüber, G. Dickneite, M. Reers, and E. Petzinger. First-pass elimination of a peptidomimetic thrombin inhibitor is due to carrier-mediated uptake by the liver. Biochem. Pharmacol. 52:85-96 (1996).
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 85-96
    • Eckhardt, U.1    Stüber, W.2    Dickneite, G.3    Reers, M.4    Petzinger, E.5
  • 12
    • 0029073966 scopus 로고
    • pH-dependent oral absorption of L-735,524, a potent HIV protease inhibitor, in rats and dogs
    • J. H. Lin, I.-W. Chen, K. J. Vastag, and D. Ostovic. pH-dependent oral absorption of L-735,524, a potent HIV protease inhibitor, in rats and dogs. Drug Metab. Dispos. 23:730-735 (1995).
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 730-735
    • Lin, J.H.1    Chen, I.-W.2    Vastag, K.J.3    Ostovic, D.4
  • 13
    • 0030768740 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationship of potent thrombin inhibitors: Piperazides of 3-amidinopenylalanine
    • J. Stürzebecher, D. Prasa, J. Hauptmann, P. Wikström, and H. Vieweg. Synthesis and structure-activity relationship of potent thrombin inhibitors: Piperazides of 3-amidinopenylalanine. J. Med. Chem. 40:3091-3099 (1997).
    • (1997) J. Med. Chem. , vol.40 , pp. 3091-3099
    • Stürzebecher, J.1    Prasa, D.2    Hauptmann, J.3    Wikström, P.4    Vieweg, H.5
  • 14
    • 0014878115 scopus 로고
    • Effects of phenobarbital on the plasma disappearance and biliary excretion of drugs in rats
    • C. D. Klaassen. Effects of phenobarbital on the plasma disappearance and biliary excretion of drugs in rats. J. Pharmacol. Exp. Ther. 175:289-300 (1970).
    • (1970) J. Pharmacol. Exp. Ther. , vol.175 , pp. 289-300
    • Klaassen, C.D.1
  • 15
    • 0344306520 scopus 로고    scopus 로고
    • Uptake in rat hepatocytes and hepatic clearance in vivo of cationic amidinophenylalanine-derived peptidomimetic thrombin inhibitors
    • Abstr.
    • J. Hauptmann, F. Etemad. K. Ziegler, J. Stürzebecher, and E. Petzinger. Uptake in rat hepatocytes and hepatic clearance in vivo of cationic amidinophenylalanine-derived peptidomimetic thrombin inhibitors. Naunyn-Schmiedeberg's Arch. Pharmacol. 355:Suppl., R 8 (1997) (Abstr.).
    • (1997) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.355 , Issue.SUPPL.
    • Hauptmann, J.1    Etemad, F.2    Ziegler, K.3    Stürzebecher, J.4    Petzinger, E.5
  • 16
    • 0011813433 scopus 로고
    • Transport of organic anions in the liver
    • E. Petzinger. Transport of organic anions in the liver. Rev. Physiol. Biochem. Pharmacol. 123:49-211 (1994).
    • (1994) Rev. Physiol. Biochem. Pharmacol. , vol.123 , pp. 49-211
    • Petzinger, E.1
  • 17
    • 0018610485 scopus 로고
    • Hepatic extraction of nonmetabolizable xenobiotics in rats
    • T. Iga and C. D. Klaassen. Hepatic extraction of nonmetabolizable xenobiotics in rats. J. Pharmacol. Exp. Ther. 211:690-697 (1979).
    • (1979) J. Pharmacol. Exp. Ther. , vol.211 , pp. 690-697
    • Iga, T.1    Klaassen, C.D.2
  • 18
    • 0030728254 scopus 로고    scopus 로고
    • Molecular properties of hepatic uptake systems for bile acids and organic anions
    • B. Hagenbuch. Molecular properties of hepatic uptake systems for bile acids and organic anions. J. Membrane Biol. 160:1-8 (1997).
    • (1997) J. Membrane Biol. , vol.160 , pp. 1-8
    • Hagenbuch, B.1
  • 19
    • 0001151469 scopus 로고    scopus 로고
    • Effect of hepatic function on the pharmacokinetics and pharmacodynamics of argatroban
    • Abstr.
    • J. Hursting, J. C. Becker, J. L. Joffrion, G. D. Knappenberger, and R. P. Schwarz. Effect of hepatic function on the pharmacokinetics and pharmacodynamics of argatroban. Thromb. Haemostas. Suppl. 1997:483 (1997) (Abstr.).
    • (1997) Thromb. Haemostas. , Issue.1997 SUPPL. , pp. 483
    • Hursting, J.1    Becker, J.C.2    Joffrion, J.L.3    Knappenberger, G.D.4    Schwarz, R.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.