Intestinal lymphangiectasia, a disease characterized by selective loss of naive CD45RA+ lymphocytes into the gastrointestinal tract

European Journal of Immunology

Volumn 28, Issue 12, 1998, Pages 4275-4285

  Fuss, Ivan J ^a   Strober, Warren ^a   Cuccherini, Brenda A ^a   Pearlstein, Glen R ^a   Bossuyt, Xavier ^b   Brown, Margaret ^b   Fleisher, Thomas A ^b   Horgan, Kevin ^c  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cytokine; Lymphangiectasia; Lymphocyte

Indexed keywords

CD27 ANTIGEN; CD31 ANTIGEN; CD45 ANTIGEN; CD69 ANTIGEN; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 4;

ADULT; ARTICLE; CASE REPORT; CONTROLLED STUDY; CYTOKINE PRODUCTION; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; INTESTINE LYMPHANGIECTASIA; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0031771014     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1521-4141(199812)28:12<4275::aid-immu4275>3.0.co;2-p     Document Type: Article

References (58)

1. Sanders, M. E., Makgoba, M. W. and Shaw, S., Human naive and memory T cells: reinterpretation of helperinducer and suppressor-inducer subsets, Immunol. Today 1988. 9: 195-199.
2. Clement, L. T., Yamashita, N. and Martin, A. M., The functionally distinct subpopulations of human CD4+ helper/inducer T lymphocytes defined by anti-CD45R antibodies derive sequentially from a differentiation pathway that is regulated by activation-dependent postthymic differentiation. J. Immunol. 1988. 141: 1464-1470.
3. Mosmann, T. R. and Coffman, R. L., Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv. Immunol. 1989. 46: 111-147.
4. Mosmann, T. R. and Coffmann, R. L., Different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 1989. 7: 145-173.
5. Abbas, A. K., Murphy, K. M. and Sher, A., Functional diversity of helper T lymphocytes. Nature 1996, 383: 787-793.
6. Waldmann, T. A., Protein-losing enteropathy. Gastroenterology 1966. 50: 422-443.
7. Kinmonth, J. B. and Cox, S. J., Protein-losing enteropathy in primary lymphoedema: Mesenteric lymphography and gut resection. Br. J. Surg. 1974. 61: 589-593.
8. Levine, C., Primary disorders of lymphatic vessels-a unified concept. J. Pediatr. Surg. 1989. 24: 233-240,
9. Hennekam, R. C., Geerdink, R. A., Hamel, B. C., Hennekam, F. A., Kraus, P., Rommeloo, J. A. and Tillemans, A. A., Autosomal recessive intestinal lymphangiectasia and lymphedema, with facial anomalies and mental retardation. Am. J. Med. Genet. 1989. 34: 593-600.
10. Mucke, J., Hoepffner, W., Scheerschmidt, G., Hornig, H. and Beyreiss, K., Early onset lymphedema, recessive form - a new form of genetic lymphedema syndrome. Eur. J. Pediatr. 1986. 145: 195-198.
11. Wilkinson, P., Pinto, B. and Senior, J. R., Reversible protein-losing enteropathy with intestinal lymphangiectasia secondary to chronic constrictive pericarditis. N. Engl. J. Med. 1965. 273: 1178-1181.
12. Nelson, D. L., Blaese, R. M., Strober, W., Bruce, R. and Waldmann, T. A., Constrictive pericarditis, intestinal lymphangiectasia, and reversible immunologie deficiency. J. Pediatr. 1975. 86: 548-554.
13. Waldmann, T. A., Strober, W. and Blaese, R. M., Immunodeficiency disease and malignancy. Ann. Intern. Med. 1972. 77: 605-628.
14. Broder, S., Cullihan, T. R., Jaffe, E. S., DeVita, V. T., Strober, W., Bartter, F. C. and Waldmann, T. A., Resolution of longstanding protein-losing enteropathy in a patient with intestinal lymphangiectasia after treatment for malignant lymphoma. Gastroenterology 1981. 80: 166-168.
15. Takagi, S., Oshimi, K., Sumiya, M., Gonda, N., Kano, S. and Takaku, F., Protein-losing enteropathy in systemic lupus erythematosus. Am. J. Gastroenterol. 1983. 3: 152-154.
16. Warshaw, A. L., Waldmann, T. A. and Laster, L., Protein-losing enteropathy and malabsorption in regional enteritis: cure by limited ileal resection. Ann. Surg. 1973. 178: 578-580.
17. Strober, W., Wochner, R. D., Carbone, P. P. and Waldmann, T. A., Intestinal lymphangiectasia: a protein-losing enteropathy with hypogammaglobulinemia, lymphocytopenia and impaired homograft rejection. J. Clin. Invest. 1967. 46: 1643-1656.
18. Weiden, P. L., Blaese, R. M., Strober, W., Block, J. B. and Waldmann, T. A., Impaired lymphocyte transformation in intestinal lymphangiectasia: evidence for at least two functionally distinct lymphocyte populations in man. J. Clin. Invest. 1972. 51: 1319-1325.
19. Sorenson, R. V., Halpin, T. C., Abramowsky, C. R., Hornick, D. L., Miller, K. M., Naylor, P. and Incefy, G. S., Intestinal lymphangiectasia and thymic hypoplasia. Clin. Exp. Immunol. 1985. 59: 217-226.
20. Yamamota, H., Tsutsui, T., Mayumi, M. and Kasakura, S., Immunodeficiency associated with selective loss of helper/inducer T cells and hypogammaglobulinemia in a child with intestinal lymphangiectasia. Clin. Exp. Immunol. 1989. 75: 196-200.
21. Muller, C., Wolf, H., Gottlicher, J., Zielinski, C. C. and Eibl, M. M., Cellular immunodeficiency in protein-losing enteropathy, predominant reduction of CD3+ and CD4+ lymphocytes. Dig. Dis. Sci. 1991. 36: 116-122.
22. Heresbach, D., Raoul, J., Genetet, N., Noret, P., Siproudhis, L., Ramee, M. P., Bretagne, J. F. and Gosselin, M., Immunological study in primary intestinal lymphangiectasia. Digestion 1994. 55: 59-64.
23. Hintzen, R. Q., De Jong, R., Lens, S. and Van Lier, R. A., CD27: marker and mediator of T-cell activation? Immunol. Today. 1994. 15: 307-311.
24. Caruso, A., Licenziati, S., Corulli, M., Canaris, A., DeFrancesco, M. A., Fiorentini, S., Peroni, L., Fallacara, F., Dima, F., Balsari, A. and Turano, A., Flow cytometric analysis of activation markers on stimulated T cells and their correlation with cell proliferation. Cytometry 1997. 27: 717-729.
25. DeJong, R., Brouwer, M., Hoolibrink, B., Van der Pouw-Kraan, T., Miedema, F. and van Lier, R. A. W., The CD27-subset of peripheral blood memory CD4+ lymphocytes contains functionally differentiated T lymphocytes that develop by persistent antigenic stimulation in vivo. Eur J. Immunol. 1992. 22: 993-999.
26. DeJong, R., Brouwer, M., Kupiper, H. M., Hooibrink, B., Miedema, F. and van Lier, R. A. W., Maturation and differentiation-dependent responsiveness of human CD4+ T helper subsets. J. Immunol. 1992. 149: 2795-2802.
27. Sunder-Plassmann, R., Majdic, O., Knapp, W. and Hotter, W., High IL-4 production is a stable phenotype of CD8negCD45RanegCD27neg T cells. Cell. Immunol. 1995. 160: 309-313.
28. Demeure, C. E., Byun, D. G., Yang, L. P., Vezzio, N. and Delespesse, G., CD31 (PECAM-1) is a differentiation antigen lost during human CD4 T cell maturation into Th1 or Th2 effector cells. Immunology 1996. 88: 110-115.
29. Jackson, D. G. and Bell, J. I., Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous patterns of expression during lymphocyte differentiation. J. Immunol. 1990. 144: 2811-2815.
30. Gold, R. H. and Youker, I. E., ldiopathic intestinal lymphangiectasia (primary protein-losing enteropathy). Lymphographic verification of enteric and peritoneal leakage of chyle. Radiology 1973. 109: 315-316.
31. Cluysennaer, O. J., Corstens, F. H. and Hafkenshew, J. C., Mechanisms of hypoalbuminemia in coeliac sprue. In Hekkens, W. and Pena, A. S. (Eds.) Coeliac Disease. Proceedings of the Second International Coeliac Symposium. Stenfert Kroesse, Leiden 1974, pp 386-396.
32. Springer, T. A., Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Celk 1994. 76: 301-314.
33. Gallatin, M., St. John, T. P., Sigelman, M., Reichert, R., Butcher, E. C. and Weissman, I. L., Lymphocyte homing receptors. Cell 1986. 44: 673-680.
34. Farstad, I. N., Norstein, J. and Brandtzaeg, P., Phenotypes of B and T cells in human intestinal and mesenteric lymph. Gastroenterology 1997. 112: 163-173.
35. MacKay, C. R., Andrew, D. P., Briskin, M., Ringler, D. J. and Butcher, E. C., Phenotype, and migration properties of three major subsets of tissue homing T cells in sheep. Eur. J. Immunol. 1996. 26: 2433-2439.
36. Abitorabi, M. A., Mackay, C. R., Jerome, E. H., Osorio, O., Butcher, E. C. and Erle, D. J., Differential expression of homing molecules on recirculating lymphocytes from sheep gut, peripheral, and lung lymph. J. Immunol. 1996. 156: 3111-3117.
37. Mclean, A. R. and Michie, C. A., In vivo estimates of division and death rates of human T lymphocytes. Proc. Natl. Acad. Sci. USA 1995. 92: 3707-3711.
38. Beverly, P. C., Michie, C. A. and Young, J. L., Memory and the lifespan of human T lymphocytes. Leukemia 1993. 52: 50-54.
39. Baars, P. A., Maurice, M. M., Rep, M., Hooibrink, B. and van Lier, R. A. W., Heterogeneity of the circulating human CD4+ T cell population. Further evidence that the CD4+CD45RA-CD27-T cell subset contains specialized primed T cells. J. Immunol. 1995. 154: 17-25.
40. Kobata, T, Agematsu, K., Kameoka, J., Schlossman, S. F. and Morimoto, C., CD27 is a signal-transducing molecule involved in CD45RA+ naive T cell costimulation. J. Immunol. 1994. 153: 5422-5432.
41. Hol, B. E. A., Hintzen, R. Q., van Lier, R. A. W., Alberts, C., Out, T. A. and Jansen, H. M., Soluble and cellular markers of T cell activation in patients with pulmonary sarcoidosis. Am. Rev. Respir. Dis. 1993. 148: 643-649.
42. Elson, L. H., Shaw, S., van Lier, R. A. W. and Nutman, T. B., T cell subpopulation phenotypes in filarial infections: CD27 negativity defines a population greatly enriched for Th2 cells. Int. Immunol. 1994. 6: 1003-1009.
43. Muller, W., Weigl, S. A., Deng, X. and Phillips, D. M., PECAM-1 is required for transendothelial migration of leucocytes. J. Exp. Med. 1993. 178: 449-460.
44. Biselli, R., Matricardi, M., D'Amelio, R. and Fattorossi, A., Multiparametric flow cytometric analysis of the kinetics of surface molecule expression after polyclonal activation of human peripheral blood T lymphocytes. Scand. J. Immunol. 1992. 35: 439-447.
45. Ahmann, A. J. and Burman, K. D., The role of T lymphocytes in autoimmune thyroid disease. Endocrinol. Metab. Clin. North Am. 1987. 16: 287-326.
46. Bongioanni, P., Fioretti, C., Vanacore, R., Bianchi, F., Lombardo, F., Ambrogi, F. and Meucci, G., Lymphocyte subsets in multiple sclerosis. A study with twocolour fluoresence analysis. J. Neurol. Sci. 1996. 139: 71-77.
47. Bofill, M., Mocroft, A., Lipman, M., Medina, E., Borthwick, N. J., Sabin, C. A., Timms, A., Winter, M., Baptista, L., Johnson, M. A., Lee, C. A., Phillips, A. N. and Janossy, G., Increased numbers of primed activated CD8+CD38+CD45RO+ T cells predict the decline of CD4+ T cells in HIV-1 infected patiente. AIDS. 1996. 827-834.
48. Webb, S., Hutchinson, J., Hayden, K. and Sprent, J., Expansion/deletion of mature T cells exposed to endogenous superantigens in vivo. J. Immunol. 1994. 152: 586-597.
49. Roman, L, I., Manzano, L., De La Hera, A., Abreu, L., Rossi, I. and Alvarez-Mon, M., Expanded CD4+CD45RO+ phenotype and defective proliferative response in T lymphocytes from patients with Crohn's disease. Gastroenterology 1996. 110: 1008-1019.
50. Tortorella, C., Schulze-Koops, H., Thomas, R., Splawski, J. B., Davis, L. S., Picker, L. J. and Lipsky, P. E., Expression of CD45RB and CD27 identifies subsets of CD4+ memory T ceils with different capacities to induce B cell differentiation. J. Immunol. 1995. 155: 149-162.
51. King, C., Stupi, R., Craighead, N., June, C. and Thyphronitis, G., CD28 activation promotes Th2 subset differentiation by human CD4+ cells. Eur. J. Immunol. 1995. 25: 587-595.
52. Benito, J. M., Abay, J. M., Gill, J., Bermejo, M., Escudero, A., Sanchez, E. and Fernandez-Cruz, E., Quantitative alterations of the functionally distinct subsets of CD4 and CD8 T lymphocytes in asymptomatic HIV infections. J. Acquir. Immunol. Defic. Syndr. 1997. 14: 128-135.
53. Woods, T. C., Roberts, B. D., Butera, S. T. and Folks, T. M., Loss of inducible virus in CD45RA naive cells after human immunodeficiency virus-1 entry accounts for preferential viral replication in CD45RO memory cells. Blood 1997. 89: 1635-1641.
54. Lane, H. C., The generation of CD4 T lymphocytes in patients with HIV infection. J. Biol. Regul. Homeost. Agents 1995. 9: 107-109.
55. Yokoyama, W. M., Monoclonal antibody supernatant and ascites fluid production. In Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M. and Strober, W. (Eds.) Current Protocols in Immunology. Greene Publishing and Wiley Intersciences, New York 1991, Ch. 2.6.4.
56. Horgan, K. and Shaw, S., Immunogenetic purification of T cell subpopulation. In Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M. and Strober, W. (Eds.) Current Protocols in Immunology. Greene Publishing and Wiley Intersciences, New York 1991, Ch. 7.4.1.
57. Kanof, M. E., Preparation of human mononuclear cell populations and subpopulations. In Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M. and Strober, W. (Eds.) Current Protocols in Immunology. Greene Publishing and Wiley Intersciences, New York 1991, Ch. 7.1.1 and 7.2.
58. Bossuyt, X., Marti, G. and Fleisher, T. A., Comparative analysis of whole blood lysis methods for flow cytometry. Cytometry 1997. 30: 124-133.