Regulation of glucose transport and c-fos and egr-1 expression in cells with mutated or endogenous growth hormone receptors

Endocrinology

Volumn 139, Issue 4, 1998, Pages 1863-1871

  Gong, Tzy Wen L ^a   Meyer, Debra J ^a   Liao, Jinfang ^a   Hodge, Christina L ^a   Campbell, George S ^a   Wang, Xueyan ^a   Billestrup, Nils ^b   Carter Su, Christin ^a   Schwartz, Jessica ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b HAGEDORN RESEARCH INSTITUTE   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGLUCOSE; GROWTH HORMONE RECEPTOR; HERBIMYCIN; STAUROSPORINE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHO CELL; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; GLUCOSE TRANSPORT; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSCRIPTION REGULATION;

EID: 0031766632     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.4.5893     Document Type: Article

References (74)

1. Carter-Su C, Schwartz J, Smit LS 1996 Molecular mechanism of growth hormone action. Annu Rev Physiol 58:187-207
2. Sliva D, Wood TJJ, Schindler C, Lobie PE, Norstedt G 1994 Growth hormone specifically regulates serine protease inhibitor gene transcription via gamma-activated sequence-like DNA elements. J Biol Chem 269:26208-26214
3. Enberg G, Hulthen A, Moller C, Norstedt G, Francis SM 1994 Growth hormone (GH) regulation of a rat serine protease inhibitor fusion gene in cells transfected with GH receptor cDNA. J Mol Endocrinol 12:39-46
4. 2+ oscillations and gene transcription. Proc Natl Acad Sci USA 92:2725-2729
5. Wang X, Souza SC, Kelder B, Cioffi JA, Kopchick JJ 1995 A 40-amino acid segment of the growth hormone receptor cytoplasmic domain is essential for GH-induced tyrosine-phosphorylated cytosolic proteins. J Biol Chem 270:6261-6266
6. Allevato G, Billestrup N, Goujon L, Galsgaard ED, Norstedt G, Postel-Vinay MC, Kelly PA, Nielsen JH 1995 Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation. J Biol Chem 270:17210-17214
7. Hansen LH, Wang X, Kopchick JJ, Bouchelouche P, Nielsen JH, Galsgaard ED, Billestrup N 1996 Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation. J Biol Chem 271:12669-12673
8. Smit LS, Meyer DJ, Billestrup N, Norstedt G, Schwartz J, Carter-Su C 1996 The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3 and 5 by GH. Mol Endocrinol 10:519-533
9. Sotiropoulos A, Moutoussamy S, Renaudie F, Clauss M, Kayser C, Gouilleux F, Kelly PA, Finidori J 1996 Differential activation of Stat3 and Stat5 by distinct regions of the growth hormone receptor. Mol Endocrinol 10:998-1009
10. VanderKuur J, Wang X, Zhang L, Campbell G, Allevato G, Billestrup N, Norstedt G, Carter-Su C 1994 Domains of the growth hormone receptor required for Jak2 tyrosine kinase association and activation. J Biol Chem 269:21709-21717
11. Frank SJ, Gilliland G, Kraft AS, Arnold CS 1994 Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase. Endocrinology 135:2228-2239
12. Campbell GS, Christian LJ, Carter-Su C 1993 Evidence for involvement of the growth hormone receptor-associated tyrosine kinase in actions of growth hormone. J Biol Chem 268:7427-7434
13. Campbell GS, Pang L, Miyasaka T, Saltiel AR, Carter-Su C 1992 Stimulation by growth hormone of MAP kinase activity in 3T3-F442A fibroblasts. J Biol Chem 267:6074-6080
14. Winston LA, Bertics PJ 1992 Growth hormone stimulates the tyrosine phosphorylation of 42- and 45-kDa ERK-related proteins. J Biol Chem 267:4747-4751
15. Moller C, Hansson A, Enberg B, Lobie PE, Norstedt G 1992 Growth hormone (GH) induction of tyrosine phosphorylation and activation of mitogen-activated protein kinase in cells transfected with rat GH receptor cDNA. J Biol Chem 267:23403-23408
16. VanderKuur J, Allevato G, Billestrup N, Norstedt G, Carter-Su C 1995 Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2. J Biol them 270:7587-7593
17. Argetsinger LS, Hsu GW, Myers Jr MG, White MF, Billestrup N, Norstedt G, Carter-Su C 1995 Growth hormone, interferon-γ and leukemia inhibitory factor-promoted tyrosyl phosphorylation of insulin receptor substrate-1. J Biol Chem 270:14685-14692
18. Ridderstrale M, Degerman E, Tornqvist H 1995 Growth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocytes. J Biol Chem 270:3471-3474
19. Sousza SC, Frick GP, Yip R, Lobo RB, Tai L-R, Goodman HM 1995 Growth hormone stimulates tyrosine phosphorylation of insulin receptor substrate-1. J Biol Chem 269:30085-30088
20. Meyer DJ, Campbell GS, Cochran BH, Argetsinger LS, Lamer AC, Finbloom DS, Carter-Su C, Schwartz J 1994 Growth hormone induces a DNA binding factor related to the interferon-stimulated 91-kDa transcription factor. J Biol Chem 269:4701-4704
21. Campbell GS, Meyer DJ, Raz R, Levy DE, Schwartz J, Carter-Su C 1995 Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone. J Biol Chem 270:3974-3979
22. Gronowski AM, Rotwein P 1994 Rapid changes in nuclear protein tyrosine phosphorylation after growth hormone treatment in vivo. Identification of phosphorylated mitogen-activated protein kinase and stat91. J Biol Chem 269:7874-7878
23. Hill CS, Treisman R 1995 Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G proteins and polypeptide growth factors. EMBO J 14:5037-5047
24. Sheng M, Dougan ST, McFadden G, Greenberg ME 1988 Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences. Mol Cell Biol 8:2787-2796
25. Meyer DJ, Stephenson EW, Johnson L, Cochran BH, Schwartz J 1993 The serum response element can mediate induction of c-fos by growth hormone. Proc Natl Acad Sci USA 90:6721-6725
26. Liao J, Hodge CL, Meyer DJ, Ho PS, Rosenspire KC, Schwartz J 1997 Growth hormone regulates ternary complex factors and serum response factor associated with the c-fos serum response element. J Biol Chem 272:25951-25958
27. Treisman R 1992 The serum response element. Trends Biochem Sci 17:423-426
28. Treisman R 1994 Ternary complex factors: growth factor regulated transcriptional activators. Curr Opin Genet Dev 4:96-101
29. McMahon SB, Monroe JG 1995 A ternary complex factor-dependent mechanism mediates induction of egr-1 through selective serum response elements following antigen receptor cross-linking in B lymphocytes. Mol Cell Biol 15:1086-1093
30. Christy B, Nathans D 1989 Functional serum response elements upstream of the growth factor-inducible gene zif268. Mol Cell Biol 9:4889-4895
31. Davidson MB 1987 Effect of growth hormone on carbohydrate and lipid metabolism. Endocr Rev 8:115-131
32. Schwartz J, Carter-Su C 1988 Effects of growth hormone on glucose metabolism and glucose transport in 3T3-F442A cells: dependence on cell differentiation. Endocrinology 122:2247-2256
33. Moldrup A, Allevato G, Dyrberg T, Nielsen JH, Billestrup N 1991 Growth hormone action in rat insulinoma cells expressing truncated growth hormone receptors. J Biol Chem 266:17441-17445
34. Wang X, Moller C, Norstedt G, Carter-Su C 1993 Growth hormone-promoted tyrosyl phosphorylation of a 121-kDa growth hormone receptor-associated protein. J Biol Chem 268:3573-3579
35. Gurland G, Ashcom G, Cochran BH, Schwartz J 1990 Rapid events in growth hormone action. Induction of c-fos and c-jun transcription in 3T3-F442A preadipocytes. Endocrinology 127:3187-3195
36. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
37. Sukhatme VP, Cao XM, Chang LC, Tsai-Morris CH, Stamenkovich D, Ferreira PC, Cohen DR, Edwards SA, Shows TB, Curran T 1988 A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Cell 53:37-43
38. Hill CS, Marais R, John S, Wynne J, Dalton S, Treisman R 1993 Functional analysis of a growth factor-responsive transcription factor complex. Cell 73:395-406
39. Cox AD, Garcia AM, Westwick JK, Kowalczyk JJ, Lewis MD, Brenner DA, Cer CJ 1994 The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranlyated or myristylated, oncogenic ras signaling and transformation. J Biol Chem 269:19203-19206
40. Chen D, Okayama H 1987 High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 7:2745-2752
41. Shibaski Y, Asano T, Lin JL, Tsukuda K, Katagiri H, Ishihara H, Yazaki Y, Oka Y 1992 Two glucose transporter isoforms are sorted differentially and are expressed in distinct cellular compartments. Biochem J 281:829-834
42. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ 1951 Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
43. Silverman MS, Mynarcik DC, Corin RE, Haspel HC, Sonenberg M 1989 Antagonism by growth hormone of insulin-sensitive hexose transport in 3T3-F442A adipocytes. Endocrinology 125:2600-2604
44. Sotiropoulos A, Perrot-Applanat M, Dinerstein H, Pallier A, Postel-Vinay M-C, Finidori J, Kelly PA 1994 Distinct cytoplasmic regions of the growth hormone receptor are required for activation of JAK2, mitogen-activated protein kinase, and transcription. Endocrinology 135:1292-1298
45. Goujon L, Allevato G, Simonin G, Paquereau L, LeCam A, Clark J, Nielsen JH, Djiane J, Postel-Vinay M-C, Edery M, Kelly PA 1994 Cytoplasmic sequences of the growth hormone receptor necessary for signal transduction. Proc Natl Acad Sci USA 91:957-961
46. O'Neal KD, Yu-Lee LY 1993 The proline-rich motif (PRM): a novel feature of the cytokine receptor superfamily. Lymphokine Cytokine Res 12:309-312
47. Argetsinger LS, Campbell GS, Yang X, Wittuhn BA, Silvennoinen O, Ihle JN, Carter-Su C 1993 Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase. Cell 74:237-244
48. Argetsinger LS, Billestrup N, Norstedt G, White MF, Carter-Su C 1996 Growth hormone, interferon-γ, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling. J Biol Chem 271:29415-29421
49. Smit LS, VanderKuur JA, Stimage A, Han Y, Luo G, Yu-lee L-y, Schwartz J, Carter-Su C 1997 Growth hormone-induced tyrosyl phosphorylation and DNA binding activity of Stat5A and Stat5B. Endocrinol 138:3426-3434
50. Liao J-F, Rosenspire KC, Schwartz J, Regulation by growth hormone of proteins associated with the c-fos serum response element. 77th Annual Meeting of The Endocrine Society, Washington DC, 1995, p 348 (Abstract)
51. Chen CM, Clarkson RW, Xie Y, Hume DA, Waters MJ 1995 Growth hormone and CSF-1 share multiple response elements in the c-fos promoter. Endocrinology 136:4505-4516
52. Gille J, Kortenjann M, Thomae O, Moomaw C, Slaughter C, Cobb M, Shaw PE 1995 ERK phosphorylation potentiates Elk-1 mediated ternary complex formation and transactivation. EMBO J 14:951-962
53. Kortenjann M, Thomae O, Shaw PE 1994 Inhibition of v-raf-dependent c-fos expression and transformation by a kinase-defective mutant of the mitogen-activated protein kinase Erk2. Mol Cell Biol 14:4815-4824
54. Price MA, Cruzalegui FH, Treisman R 1996 The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light. EMBO J 15:6552-6563
55. Whitmarsh AJ, Yang S-H, Su MS-S, Sharrocks AD, Davis RJ 1997 Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors. Mol Cell Biol 17:2360-2371
56. Clarkson RWE, Shang CA, Monks T, Waters MJ, Early activation of transcription and regulation of transactivating factors by growth hormone. 10th International Congress of Endocrinology, San Francisco, CA, 1996, p 717 (Abstract OR50-2)
57. Rim M, Qureshi SA, Gius D, Nho J, Sukhatme VP, Foster DA 1992 Evidence that activation of the Egr-1 promoter by v-Raf involves serum response elements. Oncogene 7:2065-2068
58. Harada S, Smith RM, Smith JA, White MF, Jarett L 1996 Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation. J Biol Chem 271:30222-30226
59. Doglio A, Dani C, Grimaldi P, Ailhaud G 1989 Growth hormone stimulates c-fos gene expression by means of protein kinase C without increasing inositol lipid turnover. Proc Natl Acad Sci USA 86:1148-1152
60. Slootweg MC, vam Genesen ST, Otte AP, Duursma SA, Kruijer W 1990 Activation of mouse osteoblast growth hormone receptor: c-fos oncogene expression independent of phosphoinositide breakdown and cyclic AMP. J Mol Endocrinol 4:265-274
61. Tollet P, Legraverend C, Gustafsson J-A, Mode A 1991 A role for protein kinases in the growth hormone regulation of cytochrome P4502C12 and insulin-like growth factor-I messenger RNA expression in primary adult rat hepatocytes. Mol Endocrinol 5:1351-1358
62. Robertson LM, Kerppola TK, Vendrell M, Luk D, Smeyne RJ, Bocchiaro C, Morgan JI, Curran T 1995 Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements. Neuron 14:241-252
63. Gronowski AM, Zhong Z, Wen W, Thomas MJ, Darnell Jr JE, Rotwein P 1995 In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3. Mol Endocrinol 9:171-177
64. Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR 1994 Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70S6 kinase,DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14:4902-4911
65. Argetsinger LS, Carter-Su C 1996 Mechanism of signaling by growth hormone receptor. Physiol Rev 76:1089-1107
66. Ridderstrale M, Tornqvist H 1996 Effect of tyrosine kinase inhibitors on tyrosine phosphorylations and the insulin-like effects in response to human growth hormone in isolated rat adipocytes. Endocrinology 137:4650-4656
67. Tanner WJ, Leingang KA, Mueckler MM, Glenn KC 1992 Cellular mechanism of the insulin-like effect of growth hormone in adipocytes. Biochem J 282:99-106
68. Carter-Su C, Rozsa FW, Wang X, Stubbart JR 1988 Rapid and transitory stimulation of 3-O-methylglucose transport by growth hormone. Am J Physiol 255:E723-E729
69. Fingar DC, Birnbaum MJ 1994 A role for Raf-1 in the divergent signaling pathways mediating insulin-stimulated glucose transport. J Biol Chem 269:10127-10132
70. Kilgour E, Gout I, Anderson NG 1996 Requirement for phosphoinositide 3-OH kinase in growth hormone signalling to the mitogen-activated protein kinase and p70s6k pathways. Biochem J 315:517-522
71. Urich M, el Shemerly MY, Besser D, Nagamine Y, Ballmer-Hofer K 1995 Activation and nuclear translocation of mitogen-activated protein kinases by polyomavirus middle-T or serum depend on phosphatidylinositol 3-kinase. J Biol Chem 270:29286-29292
72. Gorin E, Tai L-R, Honeyman TW, Goodman HM 1990 Evidence for a role of protein kinase C in the stimulation of lipolysis by growth hormone and isoproterenol. Endocrinology 126:2973-2982
73. Smal J, De Meyts P 1989 Sphingosine, an inhibitor of protein kinase C, suppresses the insulin-like effects of growth hormone in rat adipocytes. Proc Natl Acad Sci USA 86:4705-4709
74. Smal J, De Meyts P 1987 Role of kinase C in the insulin-like effects of human growth hormone in rat adipocytes. Biochem Biophys Res Commun 147:1232-1240