-
1
-
-
0025605345
-
Cloning and expression of a cDNA encoding an endothelin receptor
-
Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S. Cloning and expression of a cDNA encoding an endothelin receptor. Nature 1990;348:730-732.
-
(1990)
Nature
, vol.348
, pp. 730-732
-
-
Arai, H.1
Hori, S.2
Aramori, I.3
Ohkubo, H.4
Nakanishi, S.5
-
2
-
-
0028609612
-
Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons
-
Baynash AG, Hosoda K, Giaid A, et al. Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons. Cell 1994;79:1277-1285.
-
(1994)
Cell
, vol.79
, pp. 1277-1285
-
-
Baynash, A.G.1
Hosoda, K.2
Giaid, A.3
-
3
-
-
0027203495
-
A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression
-
Benigni A, Zoja C, Corna D, et al. A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression. Kidney Int 1993;44:440-444.
-
(1993)
Kidney Int
, vol.44
, pp. 440-444
-
-
Benigni, A.1
Zoja, C.2
Corna, D.3
-
4
-
-
0026641585
-
Design of a functional antagonist of endothelin
-
Cody WL, Doherty AM, He JX, et al. Design of a functional antagonist of endothelin. J Med Chem 1992;35:3301-3303.
-
(1992)
J Med Chem
, vol.35
, pp. 3301-3303
-
-
Cody, W.L.1
Doherty, A.M.2
He, J.X.3
-
7
-
-
0028283151
-
Endothelin receptors in human coronary artery-reply
-
Davenport AP, Maguire JJ. Endothelin receptors in human coronary artery-reply. Trends Pharmacol Sci 1994;5:136-137.
-
(1994)
Trends Pharmacol Sci
, vol.5
, pp. 136-137
-
-
Davenport, A.P.1
Maguire, J.J.2
-
9
-
-
0024584618
-
Spontaneous and induced arterial disease in the dog: Pathology and pathogenesis
-
Detweiler DK. Spontaneous and induced arterial disease in the dog: Pathology and pathogenesis. Toxicol Pathol 1989;17:94-108.
-
(1989)
Toxicol Pathol
, vol.17
, pp. 94-108
-
-
Detweiler, D.K.1
-
10
-
-
0026702944
-
Cardiotoxicity of vasodilators and positive inotropic/vasodilating drugs in dogs: An overview
-
Dogterom P, Zbinden G. Cardiotoxicity of vasodilators and positive inotropic/vasodilating drugs in dogs: An overview. Crit Rev Toxicol 1992;22:203-241.
-
(1992)
Crit Rev Toxicol
, vol.22
, pp. 203-241
-
-
Dogterom, P.1
Zbinden, G.2
-
11
-
-
0026764585
-
Endothelin: A new challenge
-
Doherty AM. Endothelin: A new challenge. J Med Chem 1992;35:1493-1508.
-
(1992)
J Med Chem
, vol.35
, pp. 1493-1508
-
-
Doherty, A.M.1
-
13
-
-
7844223447
-
Discovery and development of an endothelin-A receptor selective antagonist PD 156707
-
Borchardt RT, et al., eds. New York: Plenum Press, in press
-
Doherty AM, Uprichard ACG. Discovery and development of an endothelin-A receptor selective antagonist PD 156707. In: Borchardt RT, et al., eds. Integration of pharmaceutical discovery and development: Case histories. New York: Plenum Press, 1998 (in press).
-
(1998)
Integration of Pharmaceutical Discovery and Development: Case Histories
-
-
Doherty, A.M.1
Uprichard, A.C.G.2
-
14
-
-
0030047005
-
The clinical potential of endothelin receptor antagonists in cardiovascular medicine
-
Ferro JF, Webb DJ. The clinical potential of endothelin receptor antagonists in cardiovascular medicine. Drugs 1996;51:12-27.
-
(1996)
Drugs
, vol.51
, pp. 12-27
-
-
Ferro, J.F.1
Webb, D.J.2
-
15
-
-
0027324745
-
Expression of endothelin-1 in the lungs of patients with pulmonary hypertension
-
Giaid A, Yanagisawa M, Langleben D, et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. New Engl J Med 1993;328:1732-1739.
-
(1993)
New Engl J Med
, vol.328
, pp. 1732-1739
-
-
Giaid, A.1
Yanagisawa, M.2
Langleben, D.3
-
16
-
-
0028283151
-
Endothelin receptors in human coronary artery
-
Godfraind T. Endothelin receptors in human coronary artery. Trends Pharmacol Sci 1994;15:136.
-
(1994)
Trends Pharmacol Sci
, vol.15
, pp. 136
-
-
Godfraind, T.1
-
17
-
-
7844224187
-
CI-1020 (PD 156707) prevents and reverses pulmonary hypertension in hypoxic rats
-
in press
-
Haleen SJ, Schroeder R, Walker D, et al. CI-1020 (PD 156707) prevents and reverses pulmonary hypertension in hypoxic rats. J Cardiovasc Pharmacol 1998 (in press).
-
(1998)
J Cardiovasc Pharmacol
-
-
Haleen, S.J.1
Schroeder, R.2
Walker, D.3
-
18
-
-
7844244850
-
Effects of chronic endothelin-A-receptor blockade on the progression of heart failure and survival in the cardiomyopathic hamster
-
in press
-
Haleen SJ, Keiser JA, Gallagher KP, et al. Effects of chronic endothelin-A-receptor blockade on the progression of heart failure and survival in the cardiomyopathic hamster. Circulation 1998 (in press).
-
(1998)
Circulation
-
-
Haleen, S.J.1
Keiser, J.A.2
Gallagher, K.P.3
-
19
-
-
7844232202
-
Effect of an oral endothelin A receptor antagonist in a rat model of diabetic nephropathy
-
Harron JC, O'Rourke D, Gardiner T, Chakravarthy U, Uprichard ACG, Maxwell AP. Effect of an oral endothelin A receptor antagonist in a rat model of diabetic nephropathy. J Am Soc Nephrol 1997;8:637A.
-
(1997)
J Am Soc Nephrol
, vol.8
-
-
Harron, J.C.1
O'Rourke, D.2
Gardiner, T.3
Chakravarthy, U.4
Uprichard, A.C.G.5
Maxwell, A.P.6
-
20
-
-
0024554320
-
Spontaneous extramural coronary arteritis in dogs
-
Hartman HA. Spontaneous extramural coronary arteritis in dogs. Toxicol Pathol 1989;17:138-144.
-
(1989)
Toxicol Pathol
, vol.17
, pp. 138-144
-
-
Hartman, H.A.1
-
21
-
-
0027983753
-
Contribution of endogenous generation of endothelin-1 to basal vascular tone
-
Haynes WG, Webb DJ. Contribution of endogenous generation of endothelin-1 to basal vascular tone. Lancet 1994;344:852-854.
-
(1994)
Lancet
, vol.344
, pp. 852-854
-
-
Haynes, W.G.1
Webb, D.J.2
-
22
-
-
0018746004
-
Acute cardiomyopathy induced by the vasodilating antihypertensive agent Minoxidil
-
Herman EH, Balazs T, Young R, Earl FL, Krop S, Ferrans V. Acute cardiomyopathy induced by the vasodilating antihypertensive agent Minoxidil. Toxicol Appl Pharmacol 1979;47:493-503.
-
(1979)
Toxicol Appl Pharmacol
, vol.47
, pp. 493-503
-
-
Herman, E.H.1
Balazs, T.2
Young, R.3
Earl, F.L.4
Krop, S.5
Ferrans, V.6
-
23
-
-
0025912582
-
Cloning and expression of human endothelin-1 receptor cDNA
-
Hosoda K, Nakao K, Arai H, et al. Cloning and expression of human endothelin-1 receptor cDNA. FEBS Lett 1991;287:23-26.
-
(1991)
FEBS Lett
, vol.287
, pp. 23-26
-
-
Hosoda, K.1
Nakao, K.2
Arai, H.3
-
24
-
-
0028639196
-
Targeted and natural (Piebald-Lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice
-
Hosoda K, Hammer RE, Richardson JA, et al. Targeted and natural (Piebald-Lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice. Cell 1994;9:1267-1276.
-
(1994)
Cell
, vol.9
, pp. 1267-1276
-
-
Hosoda, K.1
Hammer, R.E.2
Richardson, J.A.3
-
25
-
-
0013543367
-
The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes
-
Inoue A, Yanagisawa M, Kimura S, et al The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci USA 1989;86:2863-2867.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 2863-2867
-
-
Inoue, A.1
Yanagisawa, M.2
Kimura, S.3
-
26
-
-
0026631171
-
A selectivity. Potency and solubility enhancing modifications
-
A selectivity. Potency and solubility enhancing modifications. J Med Chem 1992;35:2139-2142.
-
(1992)
J Med Chem
, vol.35
, pp. 2139-2142
-
-
Ishikawa, K.1
Fukami, T.2
Nagase, T.3
-
27
-
-
0029814551
-
Characterization of coronary arterial lesions in the dog following administration of SK&F 95654, a phophodiesterase-III inhibitor
-
Joseph EC, Jones HB, Kerns WD. Characterization of coronary arterial lesions in the dog following administration of SK&F 95654, a phophodiesterase-III inhibitor. Toxicol Pathol 1996;24:429-435.
-
(1996)
Toxicol Pathol
, vol.24
, pp. 429-435
-
-
Joseph, E.C.1
Jones, H.B.2
Kerns, W.D.3
-
29
-
-
0028360062
-
Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1
-
Kurihara Y, Kurihara H, Suzuki H, et al. Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1. Nature 1994;368:703-710.
-
(1994)
Nature
, vol.368
, pp. 703-710
-
-
Kurihara, Y.1
Kurihara, H.2
Suzuki, H.3
-
30
-
-
0030440925
-
Receptor binding and antagonist properties of a novel endothelin receptor antagonist Tak-044 (cyclo[D-α-aspartyl-3-{(4-phenylpiperazin-1-yl)carbonyl}-L-alanyl-L-a- aspartyl-D-2-{2-thienyl}glycyl-L-leucyl-D-tryptophyl]disodium salt), in human endothelin A and endothelin B receptors
-
Masuda Y, Sugo T, Kikuchi T, et al. Receptor binding and antagonist properties of a novel endothelin receptor antagonist Tak-044 (cyclo[D-α-aspartyl-3-{(4-phenylpiperazin-1-yl)carbonyl}-L-alanyl-L-a- aspartyl-D-2-{2-thienyl}glycyl-L-leucyl-D-tryptophyl]disodium salt), in human endothelin A and endothelin B receptors. J Pharmacol Exp Ther 1996;279:675-685.
-
(1996)
J Pharmacol Exp Ther
, vol.279
, pp. 675-685
-
-
Masuda, Y.1
Sugo, T.2
Kikuchi, T.3
-
31
-
-
0029956716
-
Effects of endothelin-receptor antagonism with PD 156707 on myocardial stunning in swine
-
McClanahan TB, Mertz TE, Ignasiak DP, Junear PL, Gallagher KP. Effects of endothelin-receptor antagonism with PD 156707 on myocardial stunning in swine. J Cardiovasc Pharmacol 1996;28:679-686.
-
(1996)
J Cardiovasc Pharmacol
, vol.28
, pp. 679-686
-
-
McClanahan, T.B.1
Mertz, T.E.2
Ignasiak, D.P.3
Junear, P.L.4
Gallagher, K.P.5
-
32
-
-
7844231131
-
The effects of a specific endothelin-A (ETA) receptor antagonist on the development of chronic heart failure (HF) in the dog
-
McConnell PI, Wang W, Gallagher K, Zucker IH. The effects of a specific endothelin-A (ETA) receptor antagonist on the development of chronic heart failure (HF) in the dog. FASEB J 1996;10:A430.
-
(1996)
FASEB J
, vol.10
-
-
McConnell, P.I.1
Wang, W.2
Gallagher, K.3
Zucker, I.H.4
-
33
-
-
0030426652
-
Endothelin A receptor antagonism by PD 156707 does not reduce infarct size after coronary artery occlusion/reperfusion in pigs
-
Mertz TE, McClanahan TB, Flynn MA, et al. Endothelin A receptor antagonism by PD 156707 does not reduce infarct size after coronary artery occlusion/reperfusion in pigs. J Pharmacol Exp Ther 1996;278: 42-49.
-
(1996)
J Pharmacol Exp Ther
, vol.278
, pp. 42-49
-
-
Mertz, T.E.1
McClanahan, T.B.2
Flynn, M.A.3
-
34
-
-
0023470654
-
Cardiovascular alterations in dogs treated with hydralazine
-
Mesfin GM, Shawaryn GG, Higgins MJ. Cardiovascular alterations in dogs treated with hydralazine. Toxicol Pathol 1987;415:409-416.
-
(1987)
Toxicol Pathol
, vol.415
, pp. 409-416
-
-
Mesfin, G.M.1
Shawaryn, G.G.2
Higgins, M.J.3
-
35
-
-
0025916292
-
Acute cardiovascular toxicity induced by an adenosine agonist-antihypertensive in beagles
-
Metz AL, Dominick MA, Suchanek G, Gough AW. Acute cardiovascular toxicity induced by an adenosine agonist-antihypertensive in beagles. Toxicol Pathol 1991;19:98-107.
-
(1991)
Toxicol Pathol
, vol.19
, pp. 98-107
-
-
Metz, A.L.1
Dominick, M.A.2
Suchanek, G.3
Gough, A.W.4
-
36
-
-
0024558961
-
Integrated cardiac, renal, and endocrine actions of endothelin
-
Miller WL, Redfield MM, Burnett JC. Integrated cardiac, renal, and endocrine actions of endothelin. J Clin Invest 1989;83:317-320.
-
(1989)
J Clin Invest
, vol.83
, pp. 317-320
-
-
Miller, W.L.1
Redfield, M.M.2
Burnett, J.C.3
-
37
-
-
20244363203
-
Protective effect of a selective endothelin receptor antagonist, BQ-123, in ischemic acute renal failure
-
Mino N, Kobayashi M, Nakajima A, et al. Protective effect of a selective endothelin receptor antagonist, BQ-123, in ischemic acute renal failure. Eur J Pharmacol 1992;221:77-83.
-
(1992)
Eur J Pharmacol
, vol.221
, pp. 77-83
-
-
Mino, N.1
Kobayashi, M.2
Nakajima, A.3
-
38
-
-
0028204079
-
Plasma endothelin determination as prognostic indicator on 1-year mortality after acute myocardial infarction
-
Omland T, Lie TJ, Aakvaag A, Aarsland T, Dickstein K. Plasma endothelin determination as prognostic indicator on 1-year mortality after acute myocardial infarction. Circulation 1994;89:1573-1579.
-
(1994)
Circulation
, vol.89
, pp. 1573-1579
-
-
Omland, T.1
Lie, T.J.2
Aakvaag, A.3
Aarsland, T.4
Dickstein, K.5
-
39
-
-
7844244129
-
The endothelin-A antagonist PD 156707 is not neuroprotective in a model of experimental stroke
-
Onley D, Yenari M, Sun GH, Kunis D, Steinberg GK. The endothelin-A antagonist PD 156707 is not neuroprotective in a model of experimental stroke. Soc Neurosci Abstr 1997;23:2440.
-
(1997)
Soc Neurosci Abstr
, vol.23
, pp. 2440
-
-
Onley, D.1
Yenari, M.2
Sun, G.H.3
Kunis, D.4
Steinberg, G.K.5
-
40
-
-
0028808723
-
Therapeutic potential of endothelin receptor antagonists in experimental stroke
-
Patel TR, Galbraith SL, McAuley MA, Doherty AM, Graham DI, McCulloch J. Therapeutic potential of endothelin receptor antagonists in experimental stroke. J Cardiovasc Pharmacol 1995;26:S412-S415.
-
(1995)
J Cardiovasc Pharmacol
, vol.26
-
-
Patel, T.R.1
Galbraith, S.L.2
McAuley, M.A.3
Doherty, A.M.4
Graham, D.I.5
McCulloch, J.6
-
41
-
-
0030002905
-
Therapeutic potential of endothelin receptor antagonists in cerebrovascular disease
-
Patel TR. Therapeutic potential of endothelin receptor antagonists in cerebrovascular disease. CNS Drugs 1996;5:293-310.
-
(1996)
CNS Drugs
, vol.5
, pp. 293-310
-
-
Patel, T.R.1
-
42
-
-
0029745602
-
Endothelin receptor antagonist increases cerebral perfusion and reduces ischaemic damage in feline focal cerebral ischaemia
-
Patel TR, Galbraith S, Graham DI, Hallak H, Doherty AM, McCulloch J. Endothelin receptor antagonist increases cerebral perfusion and reduces ischaemic damage in feline focal cerebral ischaemia. J Cereb Blood Flow Metab 1996;16:950-958.
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 950-958
-
-
Patel, T.R.1
Galbraith, S.2
Graham, D.I.3
Hallak, H.4
Doherty, A.M.5
McCulloch, J.6
-
44
-
-
0030668734
-
Role of endothelin in hypertension of experimental chronic renal failure
-
Potter GS, Johnson RJ, Fink GD. Role of endothelin in hypertension of experimental chronic renal failure. Hypertension 1997;30:1578-1584.
-
(1997)
Hypertension
, vol.30
, pp. 1578-1584
-
-
Potter, G.S.1
Johnson, R.J.2
Fink, G.D.3
-
46
-
-
0028902649
-
Pharmacological differences between rat and human endothelin B receptors
-
Reynolds EE, Hwang O, Flynn MA, et al. Pharmacological differences between rat and human endothelin B receptors. Biochem Biophys Res Commun 1995;209:506-512.
-
(1995)
Biochem Biophys Res Commun
, vol.209
, pp. 506-512
-
-
Reynolds, E.E.1
Hwang, O.2
Flynn, M.A.3
-
47
-
-
0024512103
-
Spontaneous disseminated panarteritis in laboratory beagle dogs in a toxicity study: A possible genetic predilection
-
Ruben Z, Deslex P, Nash G, Redmond N, Poncet M, Dodd D. Spontaneous disseminated panarteritis in laboratory beagle dogs in a toxicity study: A possible genetic predilection. Toxicol Pathol 1989;17.145-152.
-
(1989)
Toxicol Pathol
, vol.17
, pp. 145-152
-
-
Ruben, Z.1
Deslex, P.2
Nash, G.3
Redmond, N.4
Poncet, M.5
Dodd, D.6
-
49
-
-
0025605930
-
Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
-
Sakurai T, Yanagisawa M, Takuwa Y, et al Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature 1990;348:732-735.
-
(1990)
Nature
, vol.348
, pp. 732-735
-
-
Sakurai, T.1
Yanagisawa, M.2
Takuwa, Y.3
-
50
-
-
77957187696
-
Coronary artery toxicity in beagle dogs given Indolidan, a type III phosphodiesterase inhibitor
-
Sandusky GE, Means JR, Yeager HK. Coronary artery toxicity in beagle dogs given Indolidan, a type III phosphodiesterase inhibitor. Fund Appl Toxicol 1993;21:228-235.
-
(1993)
Fund Appl Toxicol
, vol.21
, pp. 228-235
-
-
Sandusky, G.E.1
Means, J.R.2
Yeager, H.K.3
-
51
-
-
0026097579
-
Vascular toxicity in dogs associated with overdoses of a novel benzodiazepine receptor partial agonist
-
Schlaeppi B, Roncari G, Zahm P. Vascular toxicity in dogs associated with overdoses of a novel benzodiazepine receptor partial agonist. Arch Toxicol 1991;65:73-80.
-
(1991)
Arch Toxicol
, vol.65
, pp. 73-80
-
-
Schlaeppi, B.1
Roncari, G.2
Zahm, P.3
-
52
-
-
0024560676
-
Review of cardiovascular findings in humans treated with minoxidil
-
Sobota JT. Review of cardiovascular findings in humans treated with minoxidil. Toxicol Pathol 1989;17: 193-202.
-
(1989)
Toxicol Pathol
, vol.17
, pp. 193-202
-
-
Sobota, J.T.1
-
54
-
-
0030999847
-
Concomitant endothelin receptor subtype-A blockade during the progression of pacing-induced congestive heart failure in rabbits: Beneficial effects on left ventricular and myocyte function
-
Spinale FG, Walker JD, Mukherjee R, Iannini JP, Keever AT, Gallagher KP. Concomitant endothelin receptor subtype-A blockade during the progression of pacing-induced congestive heart failure in rabbits: Beneficial effects on left ventricular and myocyte function. Circulation 1997;95:1918-1929.
-
(1997)
Circulation
, vol.95
, pp. 1918-1929
-
-
Spinale, F.G.1
Walker, J.D.2
Mukherjee, R.3
Iannini, J.P.4
Keever, A.T.5
Gallagher, K.P.6
-
55
-
-
0028183332
-
Endothelin in chronic renal failure
-
Takahashi K, Totsune K, Mouri T. Endothelin in chronic renal failure. Nephron 1994;66;373-379.
-
(1994)
Nephron
, vol.66
, pp. 373-379
-
-
Takahashi, K.1
Totsune, K.2
Mouri, T.3
-
56
-
-
7844226104
-
Endothelin-A receptor blockade reduces infarction after focal cerebral ischemia in the rat
-
Takasago T, McCulloch J. Endothelin-A receptor blockade reduces infarction after focal cerebral ischemia in the rat. Cereb Blood Flow Metab 1997;17(1):661.
-
(1997)
Cereb Blood Flow Metab
, vol.17
, Issue.1
, pp. 661
-
-
Takasago, T.1
McCulloch, J.2
-
57
-
-
0027765628
-
Endothelin is released from the porcine coronary circulation after short-term ischemia
-
Tonnessen T, Nasee PA, Kirkedoen KA, Offstad J, Ilebekk A, Christenson G. Endothelin is released from the porcine coronary circulation after short-term ischemia. J Cardiovasc Pharmacol (Suppl 8) 1992;22: S313-S316.
-
(1992)
J Cardiovasc Pharmacol
, vol.22
, Issue.8 SUPPL.
-
-
Tonnessen, T.1
Nasee, P.A.2
Kirkedoen, K.A.3
Offstad, J.4
Ilebekk, A.5
Christenson, G.6
-
59
-
-
0023859136
-
A novel potent vasoconstrictor peptide produced by vascular endothelial cells
-
Yanagisawa M, Hurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;332:411-415.
-
(1988)
Nature
, vol.332
, pp. 411-415
-
-
Yanagisawa, M.1
Hurihara, H.2
Kimura, S.3
|