Retinal pigment epithelial transport mechanisms and their contributions to the electroretinogram

Progress in Retinal and Eye Research

Volumn 16, Issue 4, 1997, Pages 509-566

  Gallemore, Ron P ^a   Hughes, Bret A ^b   Miller, Sheldon S ^c  

^a DUKE UNIVERSITY EYE CENTER   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; POTASSIUM;

APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL MEMBRANE TRANSPORT; ELECTROOCULOGRAM; ELECTRORETINOGRAM; EXTRACELLULAR SPACE; FLUID TRANSPORT; ION TRANSPORT; MACROMOLECULE; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA NERVE CELL;

EID: 0030751723     PISSN: 13509462     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1350-9462(96)00037-7     Document Type: Review

References (309)

1. Adorante, J. S. (1995) Regulatory volume decrease in frog retinal pigment epithelium [published erratum appears in Am. J. Physiol. 1995 Jun; 268 (6 Pt 1):section C following table of contents]. Am. J. Physiol. 268: C89-100.
2. Adorante, J. and Miller, S. (1990) Potassium-dependent volume regulation in retinal pigment epithelium is mediated by Na, K, Cl cotransport. J. gen. Physiol. 96: 1153-1176.
3. Alm, A. and Tornquist, P. (1985) Lactate transport through the blood-retinal and the blood-brain barrier in rats. Ophthalmic Res. 17: 181-184.
4. Anderson, M. and Welsh, M. (1991) Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia. Proc. natn. Acad. Sci. U.S.A. 88: 6003-6007.
5. Armstrong, W. M. and Garcia-Diaz, J. F. (1980) Ion-selective microelectrodes: theory and technique. Fed. Proc. 39: 2851-2859.
6. Barnstable, C. (1993) Glutamate and GABA in retinal circuitry. Curr. Opin. Neurobiol. 3: 520-525.
7. Besharse, J., Iuvone, P. and Pierce, M. (1988) Regulation of rhythmic photoreceptor metabolism: a role for post-receptoral neurons. Progr. Ret. Res. 7: 21-61.
8. Bialek, S., Joseph, D. and Miller, S. (1995) The delayed basolateral membrane hyperpolarization of the bovine retinal pigment epithelium: Mechanism of generation. J. Physiol. (Lond.) 484: 53-67.
9. - transport mechanisms in bovine pigment epithelium that could modulate subretinal space volume and composition. J. Physiol. (Lond.) 475: 40-47.
10. Bialek, S., Quong, J., Yu, K. and Miller, S. S. (1996) Non steroidal anti-inflammatory drugs alter chloride and fluid transport in bovine pigment epithelium. Am. J. Physiol. 270: C1175-1189..
11. Bird, A. (1994) Pathogenesis of serous detachment of the retina and pigment epithelium. Retina 2: 1019-1026.
12. Bird, A. C. (1995) Retinal photoreceptor dystrophies LI. Edward Jackson Memorial Lecture. Am. J. Ophthalmol. 119: 543-562.
13. Blazynski, C., Cohen, A., Fruh, B. and Niemeyer, G. (1989) Adenosine: Autoradiographic localization and electrophysiologic effects in the cat retina. Invest. Ophthalmol. Vis. Sci. 30: 2533-2536.
14. Blazynski, C. and Perez, M. T. (1991) Adenosine in vertebrate retina: localization, receptor characterization, and function. Cell Molec. Neurobiol. 11: 463-484.
15. Bok, D. (1982) Autoradiographic studies on the polarity of plasma membrane receptors in retinal pigment epithelial cells. In: The Structure of the Eye (J. Hollyfield, ed.), pp. 247-256. Elsevier, New York.
16. Bok, D. (1990) Processing and transport of retinoids by the retinal pigment epithelium. Eye 4: 326-332.
17. Bok, D. (1994) Retinal photoreceptor disc shedding and pigment epithelium phagocytosis. In: Retina (S. Ryan, ed.), pp. 81-94. Mosby, St. Louis, MO.
18. Botchkin, L. M. and Matthews, G. (1993) Chloride current activated by swelling in retinal pigment epithelium cells. Am. J. Physiol. 265: C1037-1045.
19. Botchkin, L. M. and Matthews, G. (1994) Voltage-dependent sodium channels develop in rat retinal pigment epithelium cells in culture. Proc. natn. Acad. Sci. U.S.A. 91: 4564-4568.
20. Boulpaep, E. L. (1971) Electrophysiological properties of the proximal tubule. Importance of cellular and intercellular pathways. In: Electrophysiology of Epithelia (G. Giebisch. ed.), pp. 91-112. F. K. Schattauer, Stuttgart.
21. Bretag, A. (1987) Muscle chloride channels. Physiol. Rev. 67: 618-720.
22. Burke, J. M., Skumatz, C. M. B., Irving, P. E. and McKay, B. S. (1996) Phenotypic heterogeneity of retinal pigment epithelial cells in vitro and in situ. Exp. Eve Res. 62: 63-73.
23. Campochiaro, P. A., Hackett, S. F. and Vinores, S. A. (1996) Growth factors in the retina and retinal pigmented epithelium. Progr. Ret. Eye Res. 15: 547-565.
24. Chader, G. (1989) Interphotoreceptor retinol-binding protein (IRBP): A model protein for molecular biological and clinically relevant studies. Invest. Ophthalmol. Vis. Sci. 30: 7-22.
25. Chader, G., Wiggert, B., Lai, Y., Lee, L. and Fletcher, R. (1983) Interphotoreceptor retinol-binding protein: A Possible role in retinoid transport to the retina. In: Progress in Retinal Research (N. Osborne and G. Chader, eds), pp. 163-189. Pergamon, Oxford.
26. Chihara, E. and Nao-i, N. (1984) Transport of subretinal fluid by the retinal pigment epithelium; studies on rhegmatogenous retinal detachment surgery without drainage of the subretinal fluid. Nippon Ganka Gakkai Zasshi 88: 1318-1323.
27. Collins, F. S. (1992) Cystic fibrosis: molecular biology and therapeutic implications. Science 256: 774-779.
28. Cox, S. N., Hay. E. and Bird, A. C. (1988) Treatment of chronic macular edema with acetazolamide. Arch. Ophthalmol. 106: 1190-1195.
29. Crosson, C. E. and Pautler, E. L. (1982) Glucose transport across isolated bovine pigment epithelium. Exp. Eye Res. 35: 371-377.
30. Dacey, D. D. (1988) Dopamine-accumulating retinal neurons revealed by in vitro fluorescence display a unique morphology. Science 240: 1196-1198.
31. Dawis, S. and Niemeyer, G. (1986) Dopamine influences the light peak in the perfused mammalian eye. Invest. Ophthalmol. Vis. Sci. 27: 330.
32. Dawis, S. and Niemeyer, G. (1987) Theophylline abolishes the light peak in perfused cat eyes. Invest. Ophthalmol. Vis. Sci. 28: 700-706.
33. Dawis, S. M. and Niemeyer, G. (1988) Similarity and diversity of monoamines in their effects on the standing potential, light peak and electroretinogram of the perfused cat eye. Clin. Vis. Sci. 3: 108-119.
34. Dawson, D. C. (1991) Principles of membrane transport. In: Handbook of Physiology - the Gastrointestinal System (S. G. Schultz, section ed., M. Field and R. A. Frizzell, vol. eds), Section 6, Vol. IV, pp. 1-44. American Physiological Society, Bethesda.
35. Dearry, A. and Burnside, B. (1988a) Stimulation of distinct D2 dopaminergic and alpha 2-adrenergic receptors induces light-adaptive pigment dispersion in teleost retinal pigment epithelium. J. Neurochem. 51: 1516-1523.
36. Dearry, A. and Burnside, B. (1988b) Dopamine induces light-adaptive retino-motor movements in teleost photoreceptors and retinal pigment epithelium. In: Dopaminergic Mechanisms in Vision (I. Bodis-Wollner, ed.), pp. 109-135. Alan Liss, New York.
37. Dearry, A. and Burnside, B. (1989) Light-induced dopamine release from teleost retinas acts as a light-adaptive signal to the retinal pigment epithelium. J. Neurochem. 53: 870-878.
38. Dearry, A., Edelman, J. L., Miller, S. S. and Burnside, B. (1990) Dopamine induces light-adaptive retinomotor movements in bullfrog cones via D2 receptors and in retinal pigment epithelium via D1 receptors. J. Neurochem. 54: 1367-1378.
39. + pump in primary cultures of Xenopus retinal pigment epithelium. Exp. Eye Res. 59: 587-596.
40. DiMattio, J. and Streitman, J. (1986) Facilitated glucose transport across the retinal pigment epithelium of the bullfrog (Rana catesbeiana). Exp. Eye Res. 43: 15-28.
41. DiMattio, J. and Streitman, J. (1991) Active transport of ascorbic acid across the retinal pigment epithelium of the bullfrog. Curr. Eye Res. 10: 959-965.
42. Dimitriev, A. V., Govardovskii, V. I. and Steinberg, R. H. (1996) Light-induced changes of principal extracellular ions and extracellular space volume in the chick retina. Invest. Ophthal. Vis. Sci. 37: S140.
43. Dowling, J. E. (1960) The chemistry of visual adaptation in the rat. Nature 188: 114-118.
44. Dragunow, M. and Faull, R. (1988) Neuroprotective effects of adenosine. Trends. Pharmac. Sci. U.S.A. 9: 193.
45. Edelman, J., Lin, H. and Miller, S. (1994a) Acidification stimulates chloride and fluid absorption across frog retinal pigment epithelium. Am. J. Physiol. 266: C946-956.
46. Edelman, J., Lin, H. and Miller, S. (1994b) Potassium-induced chloride secretion across the frog retinal pigment epithelium. Am. J. Physiol. 266: C957-966.
47. Edelman, J. and Miller, S. (1991) Epinephrine stimulates fluid absorption across bovine retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 32: 3033-3040.
48. Edelman, J. and Miller, S. (1992) Epinephrine (EP) stimulates KCl and fluid absorption across the bovine retinal pigment epithelium (RPE). Invest. Ophthalmol. Vis. Sci. 33: 1111 (abstract).
49. Ehinger, B. (1983) Functional role of dopamine in the retina. Progr. Ret. Res. 11: 213-232.
50. Faber, D. S. (1969) Analysis of the slow transretinal potentials in response to light. Ph.D. dissertation. University of New York, Buffalo.
51. 2+ exchange mechanism in apical membrane vesicles of the retinal pigment epithelium. Curr. Eye. Res. 12: 261-270.
52. Fischbarg, J., Kuang, K., Li, J., Arant-Hickman, S., Vera, J., Silverstein, S. and Loike, J. (1993) Facilitative and sodium-dependent glucose transporters behave as water channel. In: Isotonic Transport in Leaky Epithelia (H. Ussing, J. Fischbarg, O. Sten-Knudsen, E. Larsen and N. Willumsen, eds), pp. 432-449. Munksgaard, Copenhagen.
53. Fischer, S. K. and Anderson, D. H. (1994) Cellular effects of detachment on the neural retina and the retinal pigment epithelium. Retina 3: 2035-2062.
54. Fishman, G. A., Gilbert, L. D., Fiscella, R. G., Kimura, A. E. and Jampol, L. M. (1989) Acetazolamide for treatment of chronic macular edema in retinitis pigmentosa. Arch. Ophthalmol. 107: 1445-1452.
55. Flach, A. J. (1992) Cyclooxygenase inhibitors in ophthalmology. Surv. Ophthalmol. 36: 259-284.
56. Fong, C., Bialek, S., Hughes, B. and Miller, S. (1988) Modulation of intracellular chloride in bullfrog retinal pigment epithelium (RPE). Fedn Am. Soc. Exp. Biol. J. (Abstract) 2: A1722.
57. Fould, W. (1976) Clinical significance of transsceleral fluid transfer, Doyne Memorial Lecture. Trans. Ophthalmol. Soc. UK 96: 290-308.
58. Frambach, D., Fain, G., Farber, D. and Bok, D. (1990) Beta adrenergic receptors on cultured human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 31: 1767-1772.
59. Frambach, D. and Misfeldt, D. (1983) Furosemide-sensitive Cl transport in embryonic chicken retinal pigment epithelium. Am. J. Physiol. 244: F679-F685.
60. Frambach, D., Weiter, J. and Adler, A. (1985) A photogrammetric method to measure fluid movement across isolated frog retinal pigment epithelium. Biophys. J. 47: 547-552.
61. Frambach, D. A. and Marmor, M. F. (1982) The rate and route of fluid resorption from the subretinal space of the rabbit. Invest. Ophthalmol. Vis. Sci. 22: 292-302.
62. Frambach, D. A., Valentine, J. L. and Weiter, J. J. (1988a) Alpha-1 adrenergic receptors on rabbit retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 29: 737-741.
63. Frambach, D. A., Valentine, J. L. and Weiter, J. J. (1988b) Initial observations of rabbit retinal pigment epithelium-choroid-sclera preparation. Invest. Ophthalmol. Vis. Sci. 29: 814-817.
64. Frambach, D. A., Valentine, J. L. and Weiter, J. J. (1988c) Modulation of rabbit retinal pigment epithelium electrogenic transport by alpha-1 adrenergic stimulation. Invest. Ophthalmol. Vis. Sci. 29: 814-817.
65. Frambach, D. A., Valentine, J. L. and Weiter, J. J. (1989) Furosemide-sensitive Cl transport in bovine retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 30: 2271-2274.
66. Friedman, Z., Hackett, S. F. and Campochiaro, P. A. (1987) Characterization of adenylate cyclase in human retinal pigment epithelial cells in vitro. Exp. Eye Res. 44: 471-479.
67. Frizzell, R. A. (1995) Functions of the cystic fibrosis transmembrane conductance regulator protein. Am. J. Respir. Crit. Care. Med. 151: S54-58.
68. Frömter, E. (1972) The route of passive ion movement through the epithelium of Necturus gallbladder. J. Membr. Biol. 8: 259-301.
69. - conductance in toad retinal pigment epithelium. Am J. Physiol. 262: C374-C383.
70. Fuller, C. and Benos, D. (1992) CFTR! Am. J. Physiol. 263: C267-286.
71. Gallemore, R., Griff, E. and Steinberg, R. (1988) Evidence in support of a photoreceptoral origin for the 'light-peak substance'. Invest. Ophthalmol. Vis. Sci. 29: 566-571.
72. + conductances of the dark-adapted chick retinal pigment epithelium. J. Neurophysiol. 70: 1656-1668.
73. Gallemore, R., Hernandez, E. and Steinberg, R. (1994b) Choroid-free preparation of explant retinal pigment epithelium (ARVO Abstract). Invest. Ophthalmol. Vis. Sci. 35: 2348.
74. Gallemore, R., Hu, J., Hughes, B., Takahira, M. and Bok, D. (1997) Beta-2 adrenergic receptors active cyclic-AMP dependent chloride conductances in cultured human retinal pigment epithelium, (submitted)
75. Gallemore, R., Li, J., Govardovskii, V. and Steinberg, R. (1994a) Calcium gradients and light-evoked calcium changes outside rods in the intact cat retina. Vis. Neurosci. 11: 753-761.
76. - conductance in chick retinal pigment epithelium: the light peak and fast oscillation. J. Neurophysiol. 70: 1669-1680.
77. Gallemore, R. and Steinberg, R. (1989a) Effects of DIDS on the chick retinal pigment epithelium. I. Membrane potentials, apparent resistances and mechanisms. J. Neurosci. 9: 1968-1976.
78. Gallemore, R. and Steinberg, R. (1989b) Effects of DIDS on the chick retinal pigment epithelium. II. Mechanism of the light peak and other responses originating at the basal membrane. J. Neurosci. 9: 1977-1984.
79. Gallemore, R. and Steinberg, R. (1990) Effects of dopamine on the chick retinal pigment epithelium: Membrane potentials and light-evoked responses. Invest. Ophthalmol. Vis. Sci. 31: 67-80.
80. Gallemore, R. P., Hu, J., Frambach, D. A. and Bok, D. (1995) Ion transport in cultured fetal human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 36: S216 (abstract).
81. o in chick retina. Invest. Ophthalmol. Vis. Sci. 29: 103 (abstract).
82. Gallemore, R. P. and Steinberg, R. H. (1991) Cobalt increases photoreceptor-dependent responses of the chick retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 32: 3041-3052.
83. Garcia, D. M. and Burnside, B. (1994) Suppression of cAMP-induced pigment granule aggregation in RPE by organic anion transport inhibitors. Invest. Ophthalmol. Vis. Sci. 35: 178-188.
84. Geggel, H., Ament, M., Heckenlively, J., Martin, D. and Kopple, J. (1985) Nutritional requirement for taurine in patients receiving long-term paraenteral nutrition. N. Engl. J. Med. 312: 142-146.
85. Ginzburg, B. and Hogg, J. (1967) What does a short circuit current measure in biological systems? J. Theor. Biol. 14: 316-322.
86. + diffusion and prediction of light-dependent subretinal hydration in chick retina. Invest. Ophthalmol. Vis. Sci. 35, 6: 2712-2724.
87. Griff, E. (1991) Potassium-evoked responses from the retinal pigment epithelium of the toad Bufo marinus. Exp. Eye Res. 53: 219-228.
88. + pump in the frog pigment epithelium. J. gen. Physiol. 86: 853-876.
89. Griff, E. and Steinberg, R. (1982) Origin of the light peak: in vitro study of Gekko gekko. J. Physiol. (Lond). 331: 637-652.
90. o produce delayed basal membrane responses of the retinal pigment epithelium in the gekko. J. gen. Physiol. 83: 193-211.
91. Hadjiconstantinou, M., Cohen, J. and Neff, N. (1983) Epinephrine: a potential neurotransmitter in retina. J. Neurochem. 41: 1440-1444.
92. Hadjiconstantinou, M., Mariani, A., Panula, P., Joh, T. and Neff, H. (1984) Immunohistochemical evidence for epinephrine-containing retinal amacrine cell. Neuroscience 13: 547-551.
93. Haggendal, J. and Malmfors, T. (1965) Evidence of dopamine-containing neurons in the retina of rabbit. Acta Physiol. Scand. 59: 295-296.
94. Hanrahan, J., Alles, W. and Lewis, S. (1985) Single anion-selective channels in basolateral membrane of a mammalian tight epithelium. Proc. natn. Acad. Sci. U.S.A. 82: 7791-7795.
95. Harik, S. I., Kalaria, R. N., Whitney, P. M., Andersson, L., Lundahl, P., Ledbetter, S. R. and Perry, G. (1990) Glucose transporters are abundant in cells with 'occluding' junctions at the blood-eye barriers. Proc. natn. Acad. Sci. U.S.A. 87: 4261-4264.
96. Hernandez, E., Hu, J., Frambach, D. and Gallemore, R. (1995) Potassium conductances in cultured bovine and human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 36: 113-122.
97. Hille, B. (1992) Ionic Channels of Excitable Membranes, 2nd edn, pp. 341-347. Sinanuer, Sunderland, MA.
98. House, C. R. (1974) Water Transport in Cells and Tissues, pp. 390-470. Arnold, London.
99. Hu, J., Bok, D., Frambach, D. and Gallemore, R. (1995) Beta-2 adrenergic receptors activate basal membrane ion channels in cultured fetal human retinal pigment epithelium. Invest. Opthalmol. Vis. Sci. 36: 2726.
100. Hu, J., Gallemore, R., Bok, D., Lee, Y. and Frambach, D. (1994) Localization of Na, K ATPase on cultured human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 35: 3582-3588.
101. Hu, J., Gallemore, R., Bok, D. and Frambach, D. (1996a) Chloride transport in cultured fetal human retinal pigment epithelium. Exp. Eye Res. 62: 443-448.
102. Hu, J., Gallemore, R., Maruiwa, F. and Bok, D. (1996b) Retinal potassium modulates multiple ion transport mechanisms in cultured human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 37: 5229 (Abstract).
103. Huang, B. and Karwoski, C. (1989) Change in extracellular space in the frog retina. Invest Ophthalmol. Vis Sci. 30: 64.
104. Huang, B. and Karwoski, C. (1992) Light-evoked expansion of subretinal space volume in the retina of the frog. J. Neurosci. 12: 4243-4252.
105. Hudspeth, A. and Yee, A. (1973) The intercellular junctional complexes of the retinal pigment epithelia. Invest. Ophthalmol. Vis Sci. 12: 354-365.
106. Huf, E. G. (1979) Echos of the past: reflections on the early history of the concept of active transport. The Physiologist 22: 18-24.
107. 3 absorption across the retinal pigment epithelium. J. gen. Physiol. 94: 125-150.
108. Hughes, B., Miller, S. and Farber, D. B. (1987) Adenylate cyclase alters transport in frog retinal pigment epithelium. Am. J. Physiol. 252: C385-C395.
109. + pump in frog retinal pigment epithelium. Am. J. Physiol. 254: C84-98.
110. Hughes, B. and Segawa, Y. (1993) cAMP-activated chloride currents in amphibian retinal pigment epithelial cells. J. Physiol. (Lond.) 466: 749-766.
111. Hughes, B., Miller, S. and Machen, T. E. (1984) Effects of cyclic AMP on fluid absorption and ton transport across frog retinal pigment epithelium: measurements in the open-circuit state. J. gen. Physiol. 83: 875-899.
112. + conductance in toad retinal pigment epithelium. Am. J. Physiol. 268: Cl164-1172.
113. Hughes, B. A. and Steinberg, R. H. (1990) Voltage-dependent currents in isolated cells of the frog retinal pigment epithelium. J. Physiol. (Lond.) 428: 273-297.
114. + currents in isolated human retinal pigment epithelial cells. Invest. Ophthal. Vis. Sci. 37: 1125-1139.
115. + current active near resting potential in human retinal pigment epithelial cells. Am. J. Physiol. 269: C179-187.
116. Hussain, A., Kundaiker, S. and Marshall, J. (1995) Regulatory vectorial transport of taurine across bovine RPE. Invest. Ophthalmol. Vis. Sci. 36: 2730.
117. + by the retinal pigment epithelium in frog. J. Neurosci. 6: 3197-3204.
118. Jampol, L. M. and Pol, S. M. (1994) Macular edema. In: Retina (S. Ryan, ed.), Vol. 2, pp. 999-1008.
119. Jiang, C., Finkbeiner, W., Widdicombe, J., McCray, P. Jr. and Miller, S. (1993) Altered fluid transport across airway epithelium in cystic fibrosis. Science 262: 424-427.
120. Joseph, D. and Miller, S. (1989) Alpha-adrenergic receptor activation at bovine RPE apical membrane affects basolateral membrane Cl channels. Invest. Ophthalmol. Vis. Sci. 30: 413.
121. Joseph, D. and Miller, S. (1991) Apical and basal membrane ion transport mechanisms in bovine retinal pigment epithelium. J. Physiol. 435: 439-463.
122. Joseph, D. and Miller, S. (1992) Alpha-1-adrenergic modulation of K and Cl transport in bovine retinal pigment epithelium. J. gen. Physiol. 99: 263-290.
123. Joseph, D. and Miller, S. S. (1988) Alpha adrenergic receptors mediate membrane voltage and resistance changes in bovine retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 29: 20.
124. Judson, P. H. and Yannuzzi, L. A. (1994) Macular hole. In: Retina (S. J. Ryan, ed. in chief, A. P. Schachat and R. P. Murphy, eds). Vol. 2, pp. 1165-1185.
125. Karwoski, C. and Proenza, L. (1977) Relationship between Müller cell responses, a local transretinal potential, and potassium flux. J. Neurophysiol. 40: 244-259.
126. Karwoski, C. J., Lu, H. K. and Newman, E. A. (1989) Spatial buffering of light-evoked potassium increases by retinal Müller (glial) cells. Science 244: 578-580.
127. - cotransport in cultured cells derived from human retinal pigment epithelium. Am. J. Physiol. 28: C29-C34.
128. Kennedy, B. G. (1992) Rubidium transport in cultured monkey retinal pigment epithelium. Exp. Eye Res. 55: 289-296.
129. Kennedy, B. G. (1994) Volume regulation in cultured cells derived from human retinal pigment epithelium. Am. J. Physiol. 266: C676-683.
130. Kennedy, B. and Mangini, N. J. (1996) Plasma membrane calcium-ATPase in cultured human retinal pigment epithelium. Exp. Eye Res. 63: 547-556.
131. 3 cotransport at the apical membrane of bovine RPE. Invest. Ophthalmol. Vis. Sci. 35: 1759 (abstract)
132. i in bovine retinal pigment epithelium. Am. J. Physiol. (in press).
133. Kenyon, E., Yu, K., la Cour, M. and Miller, S. (1994b) Lactate transport mechanism at the apical and basolateral membranes of bovine retinal pigment epithelium. Am. J. Physiol. 267: C1561-C1573.
134. +-linked active transport of ascorbate into cultured bovine retinal pigment epithelial cells: heterologous inhibition by glucose. Membr. Biochem. 7: 115-130.
135. Khatami, M. (1990) Regulation of MI transport in retinal pigment epithelium by sugars, amiloride, and pH gradients: potential impairment of pump-leak balance in diabetic maculopathy. Membr. Biochem. 9: 279-292.
136. +-dependent myo-inositol transport by sugars in retinal pigment epithelium: role of phorbol ester and staurosporin. Membr. Biochem. 9: 263-277.
137. Khatami, M., Stramm, L. E. and Rockey, J. H. (1986) Ascorbate transport in cultured cat retinal pigment epithelial cells. Exp. Eye Res. 43: 607-615.
138. Kikawada, N. (1968) Variations in the corneo-retinal standing potential of the vertebrate eye during light and dark adaptation. Japan. J. Physiol. 18: 687-702.
139. Kirchhof, B. and Ryan, S. J. (1993) Differential permeance of retina and retinal pigment epithelium to water: implications for retinal adhesion. Int. Ophthalmol. 17: 19-22.
140. Koh, S. W. and Chader, G. J. (1984a) Retinal pigment epithelium in culture demonstrates a distinct beta-adrenergic receptor. Exp. Eye Res. 38: 7-13.
141. Koh, S. W. and Chader, G. J. (1984b) Elevation of intracellular cyclic AMP and stimulation of adenylate cyclase activity by vasoactive intestinal peptide and glucagon in the retinal pigment epithelium. J. Neurochem. 43: 1522-1526.
142. Kolker, A. and Becker, B. (1968) Epinephrine maculopathy. Arch. Ophthal. 79: 552-562.
143. Koyano, S., Araie, M. and Eguchi, S. (1993) Movement of fluorescein and its glucuronide across retinal pigment epithelium-choroid. Invest. Ophthalmol. Vis. Sci. 34: 531-538.
144. Kühne, W. (1878) On the Photochemistry of the Retina and on Visual Purple. Translation and notes by M. Foster. MacMillan, London.
145. Kumagai, A. K., Glasgow, B. J. and Pardridge, W. M. (1994) GLUT1 glucose transporter expression in the diabetic and nondiabetic human eye. Invest. Ophthalmol. Vis. Sci. 35: 2887-2894.
146. Kuntz, C., Crook, R., Dmitriev, A. and Steinberg, R. (1994) Modification by cyclic adenosine monophosphate of basolateral membrane chloride conductance in chick retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 35: 422-433.
147. la Cour, M. (1989) Rheogenic sodium-bicarbonate co-transport across the retinal membrane of the frog retinal pigment epithelium [published erratum appears in J. Physiol. (Lond.) 1992 445: 779]. J. Physiol. (Lond.) 419: 539-553.
148. 3 co-transport in frog retinal pigment epithelium. J. Physiol. (Lond.) 439: 59-72.
149. 3 co-transport in the retinal pigment epithelium. Acta. Ophthalmol. (Copenh.) 69, 4: 496-504.
150. - transport in frog retinal pigment epithelium. Exp. Eye. Res. 54, 6: 921-931.
151. la Cour, M. (1993) Ion transport in the retinal pigment epithelium. A study with ion-selective microelectrodes. Acta Ophthalmol. S209: 1-32.
152. la Cour, M., Lin, H., Kenyon, E. and Miller, S. S. (1994) Lactate transport in freshly isolated human fetal retinal pigment epithelium [published erratum appears in Invest. Ophthalmol. Vis. Sci. 1995 36: 757]. Invest. Ophthalmol. Vis. Sci. 35: 434-442.
153. la Cour, M., Lund-Andersen, H. and Zeuthen, T. (1986) Potassium transport of the frog retinal pigment epithelium: autoregulation of potassium activity in the subretinal space. J. Physiol. (Lond.) 375: 461-479.
154. Lake, N., Marshall, J. and Voaden, M. J. (1975) Studies on the uptake of taurine by the isolated neural retina and pigment epithelium of the frog. Biochem. Soc. Trans. 3: 524-525.
155. Lake, N., Marshall, J. and Voaden, M. J. (1977) The entry of taurine into the neural retina and pigment epithelium of the frog. Brain Res. 128: 497-503.
156. Lasansky, A. and De Fisch, F. (1966) Potential, current and ionic fluxes across isolated retinal pigment epithelium and choroid. J. gen. Physiol. 49: 913-924.
157. Li, J. D., Gallemore, R. P., Dmitriev, A. and Steinberg, R. H. (1994a) Light-dependent hydration of the space surrounding photoreceptors in chick retina. Invest. Ophthalmol. Vis. Sci. 35: 2700-2711.
158. Li, J. D., Govardovskii, V. I. and Steinberg, R. H. (1994b) Light-dependent hydration of the space surrounding photoreceptors in the cat retina. Vis. Neurosci. 11: 743-752.
159. i regulatory mechanisms in native human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 33: 3528-3538.
160. Lin, H., la Cour, M., Anderson, M. and Miller, S. (1994) Proton-lactate contransport in the apical membrane of frog retinal pigment epithelium. Exp. Eye Res. 59: 679-688.
161. i in bovine retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 32: 671.
162. i regulation in frog retinal pigment epithelium: two apical membrane mechanisms. Am. J. Physiol. 261: C132-C142.
163. 3 exchange at the basolateral membrane of frog retinal pigment epithelium. Am. J. Physiol. 266: C935-945.
164. Linsenmeier, R. (1986) Effects of light and darkness on oxygen distribution and consumption in the cat retina. J. gen. Physiol. 88: 521-542.
165. Linsenmeier, R. and Braun, R. (1992) Oxygen distribution and consumption in the cat retina during normoxia and hypoxemia. J. gen. Physiol. 99: 177-1197.
166. Linsenmeier, R. and Steinberg, R. (1982) Origin and sensitivity of the light peak in the intact cat eye. J. Physiol. (Lond.) 331: 653-673.
167. Linsenmeier, R. and Steinberg, R. (1983) Light-evoked interaction of apical and basal membrane of retinal pigment epithelium: c-wave and light peak. J. Neurophysiol. 50: 136-147.
168. Linsenmeier, R. and Steinberg, R. (1984) Delayed basal hyperpolarization of the cat retinal pigment epithelium, and its relation to the fast-oscillation of the DC ERG. J. gen. Physiol. 83: 213-232.
169. Livsey, C., Huang, B., Xu, J. and Karwoski, C. (1990) Light-evoked change in extracellular calcium concentration in frog retina. Vis. Res. 30: 853-861.
170. Macaluso, C., Onoe, S. and Niemeyer, G. (1992) Changes in glucose level affect rod function more than cone function in the isolated, perfused cat eye. Invest. Ophthalmol. Vis. Sci. 33: 2798-2808.
171. 2+ exchange protein and cDNA in cultured human retinal pigment epithelial cells. Invest Ophthal. Vis. Sci. 38: S467 (abstract).
172. Marmor, M. (1979) Dystrophies of the retinal pigment epithelium. In: The Retinal Pigment Epithelium (K. Zinn and M. Marmor, eds). pp. 424-453. Harvard University Press, Cambridge, MA.
173. Marmor, M. F. (1990) Control of subretinal fluid: experimental and clinical studies. Eye 4: 340-344.
174. Marmor, M. F. (1994) Mechanisms of normal retinal adhesion. Retina 3: 1931-1953.
175. Marmor, M., and Lurie, M. (1979) Light-induced electrical responses of the retinal pigment epithelium. In: The Retinal Pigment Epithelium (K. Zinn and M. Marmor, eds), pp. 226-244. Cambridge, Harvard University Press, Cambridge, MA.
176. Maruiwa, F., Gallemore, R. P., Takahira, M., Hughes, B., Hu, J. and Bok, D. (1996) Membrane polarization of potassium conductances in cultured retinal pigment epithelium. Invest. Ophthal. Vis. Sci. 37: S229.
177. Maruiwa, F., Nao-i, N., Nakazaki, S. and Sawada, A. (1995) Effects of adenosine on chick RPE membrane potentials. Curr. Eye Res. 14: 685-691.
178. Masterson, E. and Chader, G. J. (1981) Characterization of glucose transport by cultured chick pigmented epithelium. Exp. Eye Res. 32: 279-289.
179. Matsura, T., Miller, W. and Tomita, T. (1978) Cone-specific c-wave in the turtle retina. Vis. Res. 18: 767-775.
180. Mays, R. W., Beck, K. A. and Nelson, J. W. (1994) Organization and function of the cytoskeleton in polarized epithelial cells: a component of the protein sorting machinery. Curr. Opin. Cell Biol. 6: 16-24.
181. Miceli, M., Newsome, D. and Schriver, G. (1990) Glucose uptake, hexose monophosphate shunt activity, and oxygen consumption in cultured human retinal pigment epithelial cell. Invest. Ophthalmol. Vis. Sci. 31: 277-283.
182. Miller, R. F. and Dowling, J. E. (1970) Intracellular responses of the Müller (glial) cells of mudpuppy retina: their relation to b-wave of the electroretinogram. J. Neurophysiol. 33: 323-341.
183. Miller, R., Zalutsky, R. and Massey, L. (1986) A perfused rabbit retina preparation suitable for pharmacological studies. J. Neurosci. Meths 16: 309-322.
184. Miller, S. and Edelman, J. (1990) Active ion transport pathways in the bovine retinal pigment epithelium. J. Physiol. (Lond.) 424: 283-300.
185. Miller, S. and Farber, D. (1984) Cyclic AMP modulation of ion transport across frog retinal pigment epithelium. Measurements in the short-circuit state. J. gen. Physiol. 83: 853-874.
186. Miller, S. and Steinberg, R. (1976) Transport of taurine, L-methionine and 3-o-methyl-D-glucose across frog retinal pigment epithelium. Exp. Eye Res. 23, 2: 177-189.
187. Miller, S. and Steinberg, R. (1977a) Passive ionic properties of frog retinal pigment epithelium. J. Membr. Biol. 36: 337-372.
188. Miller, S. and Steinberg, R. (1977b) Active transport of ions across the frog retinal pigment epithelium. Exp. Eye Res. 25: 235-248.
189. Miller, S. and Steinberg, R. (1979) Potassium modulation of taurine transport across the frog retinal pigment epithelium. J. gen. Physiol. 74: 237-259.
190. Miller, S. and Steinberg, R. (1982) Potassium transport across the frog retinal pigment epithelium. J. Membr. Biol. 67: 199-209.
191. Miller, S. S., Hughes, B. A. and Machen, T. E. (1982) Fluid transport across retinal pigment epithelium is inhibited by cyclic AMP. Proc. natn. Acad. Sci. U.S.A. 79: 2111-2115.
192. Miller, S. S., Rabin, J., Strong, T., Iannuzzi, M., Adams, A. J., Collins, F., Reenstra, W. and McCray, Jr., P. (1992) Cystic fibrosis (CF) gene product is expressed in retina and retinal pigment epithelium. Invest. Ophthamol. Vis. Sci. 33: 1009.
193. Miller, S., Steinberg, R. and Oakley, B. II. (1978) The electrogenic sodium pump of the frog retinal pigment epithelium. J. Membr. Biol. 44: 259-279.
194. Mills, J. W. and Mandel, L. J. (1994) Cytoskeletal regulation of membrane transport events. Fedn Am. Soc. Exp. Biol. J. 8: 1161-1165.
195. Mircheff, A. K., Miller, S. S., Farber, D. B., Bradley, M. E., O'Day, W. T. and Bok, D. (1990) Isolation and provisional identification of plasma membrane populations from cultured human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 31: 863-878.
196. Miyamoto, Y. and Del Monte, M. A. (1994) Na(+)-dependent glutamate transporter in human retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 35: 3589-3598.
197. Miyamoto, Y., Kulanthaivel, P., Leibach, F. H. and Ganapathy, V. (1991) Taurine uptake in apical membrane vesicles from the bovine retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 32: 2542-2551.
198. Moroi-Fetters, S. E., Earley, O., Hirakata, A., Caron, M. G. and Jaffe, G. J. (1995) Binding, coupling, and mRNA subtype heterogeneity of alpha 1-adrenergic receptors in cultured human RPE. Exp. Eye Res. 60: 527-532.
199. Nabi, I. R., Mathews, A. P., Cohen-Gould, L., Gundersen, D. and Rodriguez-Boulan, E. (1993) Immortalization of polarized rat retinal pigment epithelium. J. Cell Sci. 104: 37-49.
200. Nao-i, N., Gallemore, R. and Steinberg, R. (1990a) Effects of cAMP and IBMX on the chick retinal pigment epithelium: membrane potentials and light-evoked responses. Invest. Ophthalmol. Vis. Sci. 31: 54-66.
201. Nao-i, N., Nilsson, S., Gallemore, R. and Steinberg, R. (1990b) Effects of melatonin on the chick retinal pigment epithelium: membrane potentials and light-evoked responses. Exp. Eye Res. 49: 573-589.
202. Nash, M. S. and Osborne, N. N. (1995) Pertussis toxin-sensitive melatonin receptors negatively coupled to adenylate cyclase associated with cultured human and rat retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 36: 95-102.
203. Nash, M. S. and Osborne, N. N. (1996) Cell surface receptors associated with the retinal pigment epithelium: the adenylate cyclase and phospholipase C signal transduction pathways. Progr. Ret. Eye. Res. 15: 501-546.
204. Nathanson, I., Widdicombe, J. H. and Nadel, J. A. (1983) Effect of amphotericin B on ion and fluid transport across dog tracheal epithelium. J. appl. Physiol. 55: 1257-1261.
205. 3H] (±) aminocyclohexane carboxylic acid, a selective inhibitor of neuronal GABA transport. Brain Res. 176: 285-296.
206. Nedergaard, M. (1994) Direct signalling from astrocytes to neurons in cultures of mammalian brain slices. Science 263: 1768-1771.
207. Negi, A. and Marmor, M. F. (1983) The resorption of subretinal fluid after diffuse damage to the retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 24: 1475-1479.
208. Negi, A. and Marmor, M. F. (1984) Effects of subretinal and systemic osmolality on the rate of subretinal fluid resorption. Invest. Ophthalmol. Vis. Sci. 25: 616-620.
209. Neher, E. and Lux, H. D. (1973) Rapid changes of potassium concentration at the outer surface of exposed single neurons during membrane current flow. J. gen. Physiol. 61: 385-399.
210. +-ATPase in polarized epithelial cells. Science 254: 847-850.
211. Niemeyer, G. (1981) Neurobiology of mammalian eyes. Neurosci. Meths 3: 317-337.
212. Noell, W. (1952) Azide sensitive potential difference across the eye bulb. Am. J. Physiol. 170: 217-238.
213. Noell, W. (1953) Studies on the electrophysiology and metabolism of the retina. U.S.A.F. School of Aviation Medicine, Project No. 21-1201-0004. Randolf Field, Texas.
214. Noell, W. (1954) The origin of the electroretinogram. Am. J. Ophthalmol. 38: 78-90.
215. Noell, W. K., Crapper, D. R., and Paganelli, C. V. (1965) Transretrinal currents and ion fluxes. In: Transcellular Membrane Potentials and Ion Fluxes (F. Snell and W. K. Noell, eds), pp. 92-130, Gordon and Breach, New York.
216. Oakley, B. II. (1977) Potassium and the photoreceptor dependent pigment epithelial hyperpolarization. J. gen. Physiol. 70: 405-425.
217. Oakley, B. II, Flaming, D. and Brown, K. (1979) Effects of the rod receptor potential upon retinal extracellular potassium concentration. J. gen. Physiol. 74: 713.
218. Oakley, B. II. and Green, D. G. (1976) Correlation of light-induced changes in retinal extracellular potassium concentration with the c-wave of the electroretinogram. J. Neurophysiol. 39: 1117-1133.
219. + pump in frog retinal pigment epithelium. J. Membr. Biol. 44: 281-307.
220. o in the subretinal space of the frog retina. Vis. Res. 22: 767-773.
221. Oakley, B. II., Steinberg, R., Miller, S. and Nilsson, S. (1977) The in vitro frog pigment epithelial cell hyperpolarization in response to light. Invest. Ophthalmol. Vis. Sci. 16(8): 771-774.
222. O'Malley, D., Sandell, J. and Masland, R. (1992) Co-release of acetylcholine and GABA by starburst amacrine cell. J. Neurosci. 12: 1394-1408.
223. Orkand, R. K. and Opava, S. C. (1994) Glial function in homeostasis of the neuronal microenvironment. News Physiol. Sci. 9: 265-267.
224. + ATPase. Exp. Eye Res. 31: 351-360.
225. Ostwald, T. and Steinberg, R. (1981) Transmembrane components of taurine flux across frog retinal pigment epithelium. Curr. Eye Res. 1: 437-443.
226. Pang, S., Yu, H., Suen, H. and Brown, G. (1980) Melatonin in the retina of rats a diurnal rhythm. J. Endocr. 87: 89-93.
227. Pasante-Morales, H., Klethi, J., Ledig, M. and Mandel, P. (1972) Free amino acids of chicken and rat retina. Brain Res. 41: 494-497.
228. Pascuzzo, G. J., Johnson, J. E. and Pautler, E. L. (1980) Glucose transport in isolated mammalian pigment epithelium. Exp. Eye Res. 30: 53-58.
229. Pautler, E. L. and Tengerdy, C. (1986) Transport of acidic amino acids by the bovine pigment epithelium [published erratum appears in Exp Eye Res. (1987) 44: following 329]. Exp. Eye Res. 43: 207-214.
230. Pautler, E. L., Tengerdy, C., Beyer, J. and Beezley, D. (1989) Modification of leucine transport across bovine pigment epithelium by metabolic stress. Am. J. Physiol. 257: C940-947.
231. Payne, J. A., Xu, J. C., Haas, M., Lytle, C. Y., Ward, D., Forbush, B. 3rd. and Forbush, B. rd. (1995) Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon. J. biol. Chem. 270: 17977-17985.
232. Pederson, J. E. (1994) Fluid physiology of the subretinal space. Retina 3: 1955-1968.
233. Peterson, R.-U. and Reuss, L. (1983) Cyclic-AMP induced chloride permeability in the apical membrane of Necturus gallbladder epithelium. J. gen. Physiol. 81: 705-729.
234. Peterson, W. and Miller, S. (1995b) Elevation of cyclic AMP levels in the bovine retinal pigment epithelium (RPE) closes basolateral membrane Cl channels. Invest. Ophthalmol. Vis. Sci. 36: S216.
235. Peterson, W. M. and Miller, S. S. (1995a) Identification and functional characterization of a dual GABA/taurine transporter in the bullfrog retinal pigment epithelium. J. gen. Physiol. 106: 1089-1122.
236. Pfeffer, B., Clark, V., Flannery, J. and Bok, D. (1986) Membrane receptors for retinol-binding protein in cultured human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 27: 1031-1040.
237. Pfeffer, B. A. (1991) Improved methodology for cell culture of human and monkey retinal pigment epithelium. In: Progress in Retinal Research (N. Osborne and G. Chader, eds), pp. 251-291. Pergamon, Oxford, UK.
238. Phillis, J. and Wu, P. (1981) The role of adenosine and its nucleotides in central synaptic transmission. Progr. Neurobiol. 16: 187.
239. Piccolino, M., Neyton, J. and Gerschenfeld, H. (1984) Decrease of the gap-junction permeability induced by dopamine and cyclic 3′,5′-adenosine monophosphate in horizontal cells of the turtle retina. J. Neurosci. 4: 2477.
240. Quinn, R. and Miller, S. (1992) Ion transport mechanisms in native human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 33: 3513-3527.
241. Quinn, R. H. and Miller, S. S. (1993) Apical epinephrine or cyclic AMP modulates K and Cl transport in native human fetal retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci 34: 872.
242. Quong, J. N., Quinn, R. H., and Miller, S. S. (1996) Evidence for two types of chloride channels in native fetal human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 37: 51109 (Abstract)
243. Rando, R. (1992) Molecular mechanisms in visual pigment regeneration. Photochem. Photobiol. 56, 6: 1145-1156.
244. Reid, E. W. (1892) Experiments upon 'absorption without osmosis'. Br. Med. J. 1: 323-326.
245. Rink, T., Tsien, R. and Pozzan, T. (1982) Cytoplasmic pH and free Mg in lymphocytes. J. Cell Biol. 96: 189-196.
246. +-ATPase in the retinal pigmented epithelium from chicken embryo is polarized in vivo but not in primary cell culture. Exp. Eye Res. 51: 435-446.
247. Rodieck, R. (1972) Components of the electroretinogram -a reappraisal. Vis. Res. 12: 773-780.
248. Roos, A. and Boron, W. (1981) Intracellular pH. Physiol. Rev. 61: 296-434.
249. Rothman, J. E. (1996) Protein sorting by transport vesicles. Science 272: 227-234.
250. Saari, J. (1990) Enzymes and proteins of the mammalian visual cycle. In: Progress in Retinal Research (N. Osborne and G. Chader, eds), pp. 363-381, Pergamon, New York.
251. 35S]-taurine from frog retinal rod outer segments. Brain Res. 135: 186-191.
252. + pump. J. Membr. Biol. 106: 71-81.
253. +. Exp. Eye. Res. 31: 373-379.
254. Schmidt, S. Y., Berson, E. L. and Hayes, K. C. (1976) Retinal degeneration in cats fed casein I. Taurine deficiency. Invest. Ophthalmol. 15: 47-52.
255. Schmidt, S. Y. (1978) Taurine fluxes in isolated cat and rat retinas: effects of illumination. Exp. Eye Res. 26: 529-535.
256. Segawa, Y. (1987) Electrical responses of the retinal pigment epithelium to sodium bicarbonate (I). Experimental studies in animals. J. Juzen Med. Soc. 96: 1008-1021.
257. + conductance in the toad retinal pigment epithelium. J. Physiol. (Lond.) 476: 41-53.
258. Sellner, P. (1986a) The blood-retinal barrier: leucine transport by the retinal pigment epithelium. J. Neurosci. 6: 2823-2828.
259. Sellner, P. A. (1986b) The movement of organic solutes between the retina and pigment epithelium. Exp. Eye Res. 43: 631-639.
260. Sheng, Y., Gouras, P., Cao, H., Berglin, L., Kjeldbye, H., Lopez, R. and Rosskothen, H. (1995) Patch transplants of human fetal retinal pigment epithelium in rabbit and monkey retina. Invest. Ophthalmol. Vis. Sci. 36: 381-390.
261. Shirao, Y. and Steinberg, R. (1987) Mechanisms of effects of small hyperosmotic gradients on the chick RPE. Invest. Ophthalmol. Vis. Sci. 280: 2015-2025.
262. Sivakami, S., Ganapathy, V., Leibach, F. and Miyamoto, Y. (1992) The γ-aminobutyric acid transporter and its interaction with taurine in the apical membrane of the bovine retinal pigment epithelium. Biochem. J. 283: 391-397.
263. Starita, C., Hussain, A. A. and Marshall, 3. (1995) Decreasing hydraulic conductivity of Bruch's membrane: relevance to photoreceptor survival and lipofuscinoses. Am. J. Med. Genet. 57: 235-237.
264. Steinberg, R. (1985) Interaction between the retinal pigment epithelium and the neural retina. Doc. Ophthalmol. 60: 327-346.
265. Steinberg, R. (1986) Research update: Report from workshop on cell biology of retinal detachment. Exp. Eye. Res. 43: 695-706.
266. Steinberg, R. (1987) Monitoring communications between photoreceptors and pigment epithelial cells: effects of 'mild' systemic hypoxia. Friedenwald lecture. Invest. Ophthalmol. Vis. Sci. 28: 1888-1904.
267. Steinberg, R., Linsenmeier, R. and Griff, E. (1983) Three light-evoked responses of the retinal pigment epithelium. Vis. Res. 23: 1315-1323.
268. Steinberg, R., Linsenmeier, R. and Griff, E. (1985) Retinal pigment epithelial cell contributions to the electrooculogram. In: Progress in Retinal Research (N. Osborne and G. Chader, eds), Vol. IV, pp. 33-36.
269. Steinberg, R. and Miller, S. (1973) Aspects of electrolyte transport in frog pigment epithelium. Exp. Eye Res. 16: 365-372.
270. Steinberg, R., Miller, S. and Stern, W. (1978) Initial observations on the isolated retinal pigment epithelium-choroid of the cat. Invest. Ophthalmol. Vis. Sci. 17: 675-678.
271. o. Invest. Ophthalmol. Vis. Sci. 20: 414-418.
272. o in retina of intact cat eye. J. Neurophysiol. 44: 897-921.
273. Steinberg, R., Schmidt, R. and Brown, K. (1970) Intracellular responses to light from cat pigment epithelium: origin of the electroretinogram c-wave. Nature 227: 728-730.
274. Stoddard, J. and Reuss, L. (1989) pH effects on basolateral membrane ion conductances in gallbladder epithelium. Am. J. Physiol. 256: C1184-C1195.
275. Stramm, L. E. and Pautler, E. L. (1982) Transport of 3-O-methylglucose in isolated rat retinal pigment epithelial cells. Exp. Eye Res. 35: 91-97.
276. - currents in cultured rat retinal pigment epithelial cells by intracellular application of inositol-1,4,5-triphosphate: differences between rats with retinal dystrophy (RCS) and normal rats. J. Membr. Biol. 151: 189-200.
277. Swartz, M. (1994) Other diseases: drug toxicity and metabolic and nutritional conditions. Retina 2: 1755-1766.
278. Takahira, M. and Hughes, B. (1997) Isolated bovine retinal pigment epithelial cells express delayed rectifier-and M-type potassium currents. Am. J. Physiol. (in press).
279. Takata, K., Kasahara, T., Kasahara, M., Ezaki, O. and Hirano, H. (1992) Ultracytochemical localization of the erythrocyte/HepG2-type glucose transporter (GLUT1) in cells of the blood-retinal barrier in the rat. Invest. Ophthalmol. Vis. Sci. 33: 377-383.
280. Thomas, J., Buchsbaum, R., Ximniak, A. and Racker, E. (1979) Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 18: 2210-2218.
281. To, C. and Hodson, S. (1995) Glucose supply to the photoreceptor cells by retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 36: S216.
282. Tornquist, P. and Alm, A. (1979) Retinal and choroidal contribution to retinal metabolism in vivo. A study in pigs. Acta Physiol. Scand. 106: 351-357.
283. Tran, V. T. (1992) Human retinal pigment epithelial cells possess beta 2-adrenergic receptors. Exp. Eye Res. 55: 413-417.
284. Tsacopoulos, M. and Magistretti, P. J. (1996) Metabolic coupling between glia and neurons. J. Neurosci. 16, 3: 877-885.
285. Tsuboi, S. (1987) Measurement of the volume flow and hydraulic conductivity across the isolated dog retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 28: 1776-1782.
286. Tsuboi, S., Fujimoto, T., Uchihori, Y., Emi, K., Iizuka, S., Kishida, K. and Manabe, R. (1984) Measurement of retinal permeability to sodium fluorescein in vitro. Invest. Ophthalmol. Vis. Sci. 25: 1146-1150.
287. Tsuboi, S., Manabe, R. and Iizuka, S. (1986) Aspects of electrolyte transport across isolated dog retinal pigment epithelium. Am. J. Physiol. 250: F781-F784.
288. Tsuboi, S. and Pederson, J. E. (1988) Volume flow across the isolated retinal pigment epithelium of cynomolgus monkey eyes. Invest. Ophthalmol. Vis. Sci. 29: 1652-1655.
289. Ueda, Y. and Steinberg, R. (1993) Voltage-operated calcium channels in fresh and cultured rat retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 34: 3408-3418.
290. Ueda, Y. and Steinberg, R. (1994) Chloride currents in freshly isolated rat retinal pigment epithelial cells. Exp. Eye Res. 58: 331-342.
291. Ueda, Y. and Steinberg, R. H. (1995) Dihydropyridine-sensitive calcium currents in freshly isolated human and monkey retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 36: 373-380.
292. Valeton, J. and van Norren, D. (1982) Intraretinal recordings of slow electrical responses to steady illumination in monkey: Isolation of receptor responses and the origin of the light peak. Vis. Res. 22: 393-399.
293. van Norren, D. and Heynen, H. (1986) Origin of the fast oscillation in the electroretinogram of the macaque. Vis. Res. 26: 569-575.
294. Voaden, M. J., Lake, N., Marshall, J. and Morjaria, B. (1977) Studies on the distribution of taurine and other neuroactive amino acids in the retina. Exp. Eye Res. 25: 249-257.
295. Weleber, R. (1989) Fast and slow oscillations of the electro-oculogram in Best's macular degeneration and retinitis pigmentosa. Arch. Ophthalmol. 107: 530-537.
296. Welsh, M. J., Widdicombe, J. E. and Nadel, J. N. (1980) Fluid transport across the canine tracheal epithelium. J. appl. Physiol. 49: 905-909.
297. + currents in fresh and cultured cells of the human and monkey retinal pigment epithelium. J. Physiol. (Lond.) 465: 121-147.
298. + current in cultured human retinal pigment epithelial cells. J. Physiol. (Lond.) 476: 187-196.
299. Wen, R. and Oakley, B. II. (1987) Müller cell involvement in electroretinogram generation and pH regulation in the vertebrate retina. Soc. Neurosci. (Abstract) 13: 1049.
300. Winkler, B. S. (1981) Glycolytic and oxidative metabolism in relation to retinal function. J. gen. Physiol. 77: 667-692.
301. Winkler, B. S. (1989) Retinal aerobic glycolysis revisited [editorial]. Invest. Ophthalmol. Vis. Sci. 30: 1023.
302. Witkovsky, P., Dudek, F. and Ripps, H. (1975) Slow PIII component of the carp electroretinogram. J. gen. Physiol. 65: 119-135.
303. Witkovsky, P., Stone, S. and Besharse, J. (1987) Dopamine mimics light-adaptation in horizontal cells of the Xenopus retina. Soc. Neurosci. Abstr. 13: 24.
304. Wolfensberger, T. J., Chiang, R. K., Takeuchi, A. and Marmor, M. F. Inhibition of membrane bound carbonic anhydrase enhances subretinal fluid absorption and retinal adhesiveness. Invest. Ophthalmol. Vis. Sci. (in press).
305. Xu, X., Xu, J., Huang, B., Livsey, C. and Karwoski, C. (1991) Comparison of pharmacological agents (asparate vs aminophosphonobutyric plus kynurenic acids) to block synaptic transmission from retinal photoreceptors in frog. Exp. Eye Res. 52: 691-698.
306. Yamamoto, F., Borgula, G. and Steinberg, R. (1992) Effects of light and darkness on pH outside rod photoreceptors in the cat retina. Exp. Eye Res. 54: 685-697.
307. Yang, Z., Cohen, R. L., Lui, G. M., Lawrence, D. A. and Shuman, M. A. (1995) Thrombin increases expression of urokinase receptor by activation of the thrombin receptor. Invest. Ophthalmol. Vis. Sci. 36: 2254-2261.
308. Yokoyama, T., Lin, L-R., Chakrapani, B. and Reddy, V. N. (1993) Hypertonic stress increases Na-K ATPase, taurine, myoinostitol in human lens and retinal pigment epithelial cultures. Invest. Ophthalmol. Vis. Sci. 34: 2512-2517.
309. Zeuthen, T. (1995) Molecular mechanisms for passive and active transport of water. Int. Rev. Cytol. 160: 99-161.