Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 2, 1996, Pages 845-850

  Venkataraman, Ganesh ^a   Sasisekharan, V ^b   Herr, Andrew B ^c   Ornitz, David M ^c   Waksman, Gabriel ^c   Cooney, Charles L ^b   Langer, Robert ^a,b   Sasisekharan, Ram ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b USA   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; HEPARIN;

ARTICLE; CONFORMATIONAL TRANSITION; DIMERIZATION; GROWTH REGULATION; HORMONE RECEPTOR INTERACTION; PRIORITY JOURNAL; PROTEIN STABILITY; RECEPTOR BINDING;

APOPROTEINS; CARBOHYDRATE SEQUENCE; COMPUTER SIMULATION; FIBROBLAST GROWTH FACTOR 2; HEPARIN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, FIBROBLAST GROWTH FACTOR;

EID: 0030045640     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.2.845     Document Type: Article

References (38)

1. Burgess, W. H. & Macaig, T. (1989) Annu. Rev. Biochem. 58, 575-606.
2. Baird, A. & Bohlen, P. (1990) in Peptide Growth Factors and Their Receptors, eds. Sporn, M. B. & Roberts, A. B. (Springer, Berlin), pp. 369-418.
3. Basilico, C. & Moscatelli, D. (1992) Adv. Cancer Res. 59, 115-165.
4. Sasisekharan, R., Moses, M. A., Nugent. M. A., Cooney, C. L. & Langer, R. (1994) Proc. Natl. Acad. Sci. USA 91, 1524-1528.
5. Givol, D. & Yayon, A. (1992) FASEB J. 6, 3362-3369.
6. Bernfield, M., Kokenyesi, R., Kato, M., Hinkes, M. T., Spring, J., Gallo, R. L. & Lose, E. J. (1992) Annu. Rev. Cell Biol. 8, 365-393.
7. Rapraeger, A. C. (1993) Curr. Opin. Cell Biol. 5, 844-853.
8. Aviezer, D., Hecht, D., Safran, M., Eisinger, M., David, G. & Yayon, A. (1994) Cell 79, 1005-1013.
9. Pantoliano, M. W., Horlick, R. A., Springer, B. A., Van Dyk, D. E., Tobery, T., Wetmore, D., Lear, J. D., Nahapetian, A. T., Bradley, J. D. & Sisk, W. P. (1994) Biochemistry 33, 10229-10248.
10. Zhu, X., Hsu, B. T. & Rees, D. C. (1993) Structure 1, 27-34.
11. Folkman, J., Klagsbrun, M., Sasse, J., Wadzinski, M., Ingber, D. & Vlodavsky, I. (1988) Am. J. Pathol. 130, 393-400.
12. Vlodavsky, I., Fuks, Z., Ishai-Michaeli, R., Bashkin, P., Levi, E., Korner, G., Bar-Shavit, R. & Klagsbrun, M. (1991) J. Cell. Biochem. 45, 167-176.
13. Yayon, A., Klagsbrun, M., Esko, J. D., Leder, P. & Ornitz, D. M. (1991) Cell 64, 841-848.
14. Rapraeger, A. C., Krufka, A. & Olwin, B. B. (1991) Science 252, 1705-1708.
15. Ornitz, D. M., Yayon, A., Flanagan, J. G., Svahn, C. M., Levi, E. & Leder, P. (1992) Mol. Cell. Biol. 12, 240-247.
16. Klagsbrun, M. & Baird, A. (1991) Cell 67, 229-231.
17. Zhang, J., Cousens, L. S., Barr, P. J. & Sprang, S. R. (1991) Proc. Natl. Acad. Sci. USA 88, 3446-3450.
18. Zhu, X., Komiya, H., Chirino, A., Faham, S., Fox, G. M., Arakawa, T., Hsu, B. T. & Rees, D. C. (1991) Science 251, 90-93.
19. Eriksson, E. A., Cousens, L. S. & Mathews, B. W. (1993) Protein Sci. 2, 1274-1284.
20. Ago, H., Kitagawa, Y., Fujishima, A., Matsuura, Y. & Katsube, Y. (1991) J. Biochem. 110, 360-363.
21. Eriksson, E. A., Cousens, L. S. & Mathews, B. W. (1991) Proc. Natl. Acad. Sci. USA 88, 3441-3445.
22. Ornitz, D. M., Herr, A. B., Nilsson, M., Westman, J., Svahn, C.-M. & Waksman, G. (1995) Science 268, 432-436.
23. Roghani, M., Mansukhani, A., Dell'Era, P., Bellsosta, P., Basilico, C., Rifkin, D. & Moscatelli, D. (1994) J. Biol. Chem. 269, 3976-3984.
24. Mason, I. J. (1994) Cell 78, 547-552.
25. Nieduszynski, I. (1989) in Heparin, eds. Lane, D. A. & Lindhal, U. (CRC, Boca Raton, FL), pp. 52-54.
26. Mulloy, B., Foster, M. J., Jones, C. & Davies, D. B. (1993) Biochem. J. 293, 849-858.
27. Janin, J., Miller, S. & Chothia, C. (1988) J. Mol. Biol. 204, 155-164.
28. McDonald, N. Q., Lapatto, R., Murray-Rust, J., Gunning, J., Wlodawer, A. & Blundell, T. L. (1991) Nature (London) 354, 411-414.
29. Tainer, J. A., Getzoff, E. D., Richardson, J. S. & Richardson, D. C. (1983) Nature (London) 306, 284-287.
30. Ishihara, M., Tyrrell, D. J., Stauber, G. B., Brown, S., Cousens, L. S. & Stack, R. J. (1993) J. Biol. Chem. 268, 4675-4683.
31. Guimond, S., Maccarana, M., Olwin, B. B., Lindahl, U. & Rapraeger, A. C. (1993) J. Biol. Chem. 268, 23906-23914.
32. Maccarana, M., Casu, B. & Lindahl, U. (1993) J. Biol. Chem. 268, 23898-23905.
33. Heldin, C.-H. (1995) Cell 80, 213-223.
34. Wells, J. A. (1994) Curr. Opin. Cell Biol. 6, 163-173.
35. Spivak-Kroizman, T., Lemmon, M. A., Dikic, I., Ladbury, J. E., Pinchasi, D., Huang, J., Jaye, M., Crumley, G., Schlessinger, J. & Lax, I. (1994) Cell 79, 1015-1024.
36. Baird, A., Schubert, D., Ling, N. & Guillemin, R. (1988) Proc. Natl. Acad. Sci. USA 85, 2324-2328.
37. Springer, B. A., Pantoliano, M. W., Barbera, F. A., Gunyuzlu, P. L., Thompson, L. D., Herblin, W. F., Rosenfeld, S. A. & Book, G. W. (1994) J. Biol. Chem. 240, 26879-26884.
38. Nugent, M. A. & Edelman, E. R. (1992) Biochemistry 260, 8876-8883.