High throughput fluorescence-based conformation-sensitive gel electrophoresis (F-CSGE) identifies six unique BRCA2 mutations and an overall low incidence of BRCA2 mutations in high risk BRCA1-negative breast cancer families

Human Genetics

Volumn 102, Issue 5, 1998, Pages 549-556

  Ganguly, Tapan ^a   Dhulipala, Rohini ^a   Godmilow, Lynn ^a   Ganguly, Arupa ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER GENETICS; CANCER RISK; CANCER SUSCEPTIBILITY; CLINICAL GENETICS; CODON; CONTROLLED STUDY; DNA SEQUENCE; FAMILY HISTORY; FEMALE; FLUORESCENCE BASED CONFORMATION SENSITIVE GEL ELECTROPHORESIS; FRAMESHIFT MUTATION; GEL ELECTROPHORESIS; GENE FREQUENCY; GENE MUTATION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MISSENSE MUTATION; ONCOGENE; ONSET AGE; OVARY CANCER; PEDIGREE ANALYSIS; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL;

ADULT; AGED; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; BREAST NEOPLASMS, MALE; DISEASE SUSCEPTIBILITY; DNA MUTATIONAL ANALYSIS; ELECTROPHORESIS; EVALUATION STUDIES; FALSE NEGATIVE REACTIONS; FALSE POSITIVE REACTIONS; FEMALE; FLUORESCENCE; FRAMESHIFT MUTATION; GENETIC MARKERS; HUMANS; JEWS; MALE; MIDDLE AGED; MUTATION; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; PEDIGREE; RISK; TRANSCRIPTION FACTORS;

EID: 0031744841     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390050738     Document Type: Article

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