38 000 MW antigen-specific major histocompatibility complex class I restricted interferon-γ-secreting CD8+ T cells in healthy contacts of tuberculosis

Immunology

Volumn 95, Issue 4, 1998, Pages 585-590

  Wilkinson, R J ^a,b,e   Zhu, X ^a   Wilkinson, K A ^a   Lalvani, A ^c,d   Ivanyi, J ^a   Pasvol, G ^b   Vordermeier, H M ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b NORTHWICK PARK HOSPITAL   (United Kingdom)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANTIGEN SPECIFICITY; ARTICLE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; TUBERCULOSIS; VACCINIA VIRUS;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, BACTERIAL; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INTERFERON TYPE II; MALE; MIDDLE AGED; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS; VACCINES, SYNTHETIC; VACCINIA; VIRAL VACCINES;

EID: 0031741950     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1998.00648.x     Document Type: Article

References (32)

1. COLDITZ G.A., BREWER T.F., BERKEY C.S. et al. (1994) Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature, J Am Med Assoc 271, 698.
2. FLYNN J., GOLDSTEIN M., TRIEBOLD K., KOLLER B. & BLOOM B.R. (1992) Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 89, 12013.
3. COOPER A.M., D'SOUZA C., FRANK A.A. & ORME I.M. (1997) The course of Mycobacterium tuberculosis infection in the lungs of mice lacking expression of either perforin-or granzyme-mediated cytolytic mechanisms. Infect Immun 65, 1317.
4. + T cells requires the production of Interferon-γ. Infect Immun 66, 830.
5. NEWPORT M.J., HUXLEY C.M., HUSTON S. et al. (1996) A mutation in the interferon-γ receptor gene and susceptibility to mycobacterial infection. N Engl J Med 335, 1941.
6. HIRSCH C.S., HUSSAIN R., TOOSSI Z., DAWOOD G., SHAHID F. & ELLNER J.J. (1996) Cross-modulation by transforming growth factor beta in human tuberculosis: suppression of antigen-driven blastogenesis and interferon gamma production. Proc Natl Acad Sci USA 93, 3193.
7. h2 profiles in tuberculosis based on proliferation and cytokine response of blood lymphocytes to mycobacterial antigens. Immunology 81, 171.
8. BOTHAMLEY G.H., FESTENSTEIN F. & NEWLAND A. (1992) Protective role for CD8 cells in tuberculosis. Lancet 339, 315.
9. FAITH A., SCHELLENBERG D.M., REES A.D. & MITCHELL D.M. (1992) Antigenic specificity and subset analysis of T cells isolated from the bronchoalveolar lavage and pleural effusion of patients with lung disease. Clin Exp Immunol 87, 272.
10. AINSLIE G.M., SOLOMON J.A. & BATEMAN E.D. (1992) Lymphocyte and lymphocyte subset numbers in blood and in bronchoalveolar lavage and pleural fluid in various forms of human pulmonary tuberculosis at presentation and during recovery. Thorax 47, 513.
11. RANDHAWA P.S. (1990) Lymphocyte subsets in granulomas of human tuberculosis: an in situ immunofluorescence study using monoclonal antibodies. Pathology 22, 153.
12. REES A., SCOGING A., MEHLERT A., YOUNG D.B. & IVANYI J. (1988) Specificity of proliferative response of human CD8 clones to mycobacterial antigens. Eur J Immunol 18, 1881.
13. OTTENHOF T.H.M. & MUTIS T. (1995) Role of cytotoxic cells in the protective immunity against and immunopathology of intracellular infections. Eur J Clin Invest 25, 371.
14. +T cells in vitro. Immunology 87, 339.
15. STENGER S., MAZZACARRO R.J., UYEMURA K. et al. (1997) Differential effects of cytolytic T cell subsets on intracellular infection. Science 276, 1684.
16. CLEMENS D.L. & HORWITZ M.A. (1995) Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited. J Exp Med 181, 257.
17. DI FABIO S., MBAWUIKE I.N., KIYONO H., FUJIHASHI K., COUCH R.B. & MCGHEE J.R. (1994) Quantitation of human influenza virus-specific cytotoxic T lymphocytes: correlation of cytotoxicity and increased numbers of IFN-gamma producing CD8+ T cells. Int Immunol 6, 11.
18. LALVANI A., BROOKES R., HAMBLETON S., BRITTON W.J., HILL A.V.S. & MCMICHAEL A.J. (1997) Rapid effector function in CD8+ memory T cells. J Exp Med 186, 859.
19. + T lymphocytes specific for Mycobacterium tuberculosis. Proc Natl Acad Sci USA 95, 270.
20. ZHU X., VENKATAPRASAD N., THANGARAJ T. et al. (1997) Functions and specificity of T cells following nucleic acid vaccination of mice against M. tuberculosis infection. J Immunol 158, 5921.
21. ZHU X., VENKATAPRASAD N., IVANYI J. & VORDERMEIER H.M. (1997) Vaccination with recombinant Vaccinia viruses protects mice against Mycobacterium tuberculosis infection. Immunology 92, 6.
22. SINGH M., ANDERSEN Ä.B., MCCARTHY J.E.G. et al. (1992) The Mycobacterium tuberculosis 38 kDa antigen: overexpression of the gene in Escherichia coli and purification and characterisation of the recombinant product. Gene 117, 53.
23. YOUNG D., KENT L., REES A., LAMB J. & IVANYI J. (1986) Immunological activity of a 38-kilodalton protein purified from Mycobacterium tuberculosis. Infect Immun 54, 177.
24. SKIPPER J. & STAUSS H.J. (1993) Identification of two cytotoxic T lymphocyte-recognised epitopes in the RAS protein. J Exp Med 177, 1493.
25. FLYNN J., CHAN J., TRIEBOLD K., DALTON D., STEWART T. & BLOOM B. (1993) An essential role for Interferon-γ in resistance to Mycobacterium tuberculosis infection. J Exp Med 178, 2249.
26. COOPER A., DALTON D., STEWART T., GRIFFIN J., RUSSELL D. & ORME I. (1993) Disseminated tuberculosis in Interferon-γ gene-disrupted mice. J Exp Med 178, 2243.
27. ZHU X., STAUSS H., IVANYI J. & VORDERMEIER H. (1997) Specificity of CD8+ T cells from subunit-vaccinated and infected H-2b mice recognizing the 38 kDa antigen of Mycobacterium tuberculosis. Int Immunol 9, 1669.
28. DEMKOWICZ W.E. JR, LITTAUA R.A., WANG J. & ENNIS F.A. (1996) Human cytotoxic T-cell memory: long-lived responses to vaccinia virus. J Virol 70, 2627.
29. MAZZACCARO R.J., GEDDE M., JENSEN E. et al (1996) Major histocompatibility Class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 93, 117861.
30. LEFÈVRE P., BRAIBANT M., DE WIT L. et al. (1997) Three different putative phosphate transport receptors are encoded by the Mycobacterium tuberculosis genome and are present at the surface of Mycobacterium bovis BCG. J Bacteriol 179, 2900.
31. CHANG Z., CHOUDHARY A., LATHIGRA R. & QUICHO F.A. (1994) The immunodominant 38-kDa lipoprotein antigen of Mycobacterium tuberculosis is a phosphate-binding protein. J Biol Chem 269, 1956.
32. + cytotoxic cells and relative resistance of alveolar macrophage to lysis. J Immunol 159, 290.