Specificity of CD8+ T cells from subunit-vaccinated and infected H-2b mice recognizing the 38 kDa antigen of Mycobacterium tuberculosis

International Immunology

Volumn 9, Issue 11, 1997, Pages 1669-1676

  Zhu, Xiaojiu ^a   Stauss, Hans J ^a   Ivanyi, Juraj ^a   Vordermeier, H Martin ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

CD8+; Cytotoxic T lymphocyte; Epitopes; Mycobacterium tuberculosis; Tuberculosis

Indexed keywords

BACTERIAL PROTEIN; CD8 ANTIGEN; DNA VACCINE; H2 ANTIGEN; MYCOBACTERIUM ANTIGEN; MYCOBACTERIUM VACCINE; PLASMID DNA; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN RECOGNITION; ARTICLE; CYTOTOXIC T LYMPHOCYTE; FEMALE; GENETIC TRANSFECTION; H2 SYSTEM; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; VACCINATION;

ANIMALS; ANTIGENS, BACTERIAL; CD8-POSITIVE T-LYMPHOCYTES; EPITOPES; FEMALE; H-2 ANTIGENS; MICE; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; PLASMIDS; SENSITIVITY AND SPECIFICITY; T-LYMPHOCYTES, CYTOTOXIC; TRANSFECTION; TUBERCULOSIS; TUMOR CELLS, CULTURED; VACCINES, DNA; VACCINIA VIRUS;

EID: 0030732236     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/9.11.1669     Document Type: Article

References (51)

1. + T cell lines. Eur. J. Immunol. 18:59.
2. Hussein, S., Curtis, J., Griffiths, D. and Turk, J. L. 1987. Study of DTH and resistance in Mycobacterium lepraemurium infection using a T-cell line isolated from mice infected with Mycobacterium bovis (BCG). Cell. Immunol. 105:423.
3. Hussein, S., Curtis, J., Akuffo, H. and Turk, J. L. 1987. Dissociation between delayed-type hypersensitivity and resistance to pathogenic mycobacteria demonstrated by T-cell clones. Infect. Immun. 55:564
4. Flynn, J. L., Goldstein, M. M., Triebold, K. J., Koller, B. and Bloom, B. R. 1992. Major histocompatibility complex class l-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc. Natl Acad. Sci. USA 89:12013.
5. + T cells. Infect. Immun. 55:2037.
6. Guleria, I., Mukherjee, R. and Kaufmann, S. H. 1993. In vivo depletion of CD4 and CD8 T lymphocytes impairs Mycobacterium w vaccine-induced protection against M. tuberculosis in mice. Med. Microbiol. Immunol. Berl. 182:129.
7. Kaleab, B., Ottenoff, T., Converse, P., Halapi, E., Tadesse, G., Rottenberg, M. and Kiessling, R. 1990. Mycobacterial-induced cytotoxic T cells as well as nonspecific killer cells derived from healthy individuals and leprosy patients. Eur. J. Immunol. 20:2651.
8. + T cells in vitro. Immunology 87:339.
9. Rees, A., Scoging, A., Mehlert, A., Young, D. B. and Ivanyi, J. 1988. Specificity of proliferative response of human CDS clones to mycobacterial antigens. Eur. J. Immunol. 18:1881.
10. + cells in tuberculosis. Lancet 339:315.
11. Van Den Oord, J. J., De Wolf-Peeters, C., Facchetti, F. and De Smet, V. J. 1984. Cellular composition of hypersensitivity-type granulomas: immunohistochemical analysis of tuberculous and sarcoidal lymphadenitis. Hum. Path. 15:559.
12. Rhandhawa, P. S. 1990. Lymphocyte subsets in granulomas of human tuberculosis: an in situ immunofluorescence study using monoclonal antibodies. Pathology 22:153.
13. Young, D., Kent, L., Rees, A., Lamb, J. and Ivanyi, J. 1986. Immunological activity of a 38-kilodalton protein purified from Mycobacterium tuberculosis. Infect. Immun. 54:177.
14. Andersen, A. B. and Hansen, E. B. 1989. Structure and mapping of antigenic domains of protein antigen b, a 38,000-molecular-weight protein of Mycobacterium tuberculosis. Infect. Immun. 57:2481.
15. Harris, D. P., Vordermeier, H. M., Brett, S. J., Pasvol, G., Moreno, C. and Ivanyi, J. 1994. Epitope specificity and isoforms of the mycobacterial 19-kilodalton antigen. Infect. Immun. 62:2963.
16. Singh, M., Andersen, A. B., McCarthy, J. E., Rohde, M., Schutte, H., Sanders, E. and Timmis, K. N. 1992. The Mycobacterium tuberculosis 38-kDa antigen: overproduction in Escherichia coli, purification and characterization. Gene 117:53.
17. Stauss, H. J., Davies, H., Sadovnikova, E., Chain, B., Horowitz, N. and Sinclair, C. 1992. Induction of cytotoxic T lymphocytes with peptides in vitro: identification of candidate T-cell epitopes in human papilloma virus. Proc. Natl Acad. Sci. USA 89:7871.
18. d mice. Scand. J. Immunol. 42:557.
19. Vordermeier, H.-M., Coombes, A. G. A., Jenkins, P., McGee, J. P., O'Hagan, D. T., Davis, S. S. and Singh, M. 1995. Synthetic delivery systems for tuberculosis vaccines: immunological evaluation of the M. tuberculosis 38kDa protein entrapped in biodegradable PLG microparticles. Vaccine 13:1576.
20. Espitia, C. and Mancilla, R. 1989. Identification, isolation and partial characterization of Mycobacterium tuberculosis glycoprotein antigens. Clin. Exp. Immunol. 77:378.
21. Rammensee, H. G., Friede, T. and Stevanovic, S. 1995. MHC ligands and peptide motifs: first listing, Immunogenetics 41:178.
22. Schoel, B., Zugel, U., Ruppert, T. and Kaufmann, S. H. 1994. Elongated peptides, not the predicted nonapeptide stimulate a major histocompatibility complex class l-restricted cytotoxic T lymphocyte clone with specificity for a bacterial heat shock protein. Eur. J. Immunol. 24:3161.
23. Tascon, R. E., Colston, M. J., Ragno, S., Stavropoulos, E., Gregory, D. and Lowrie, D. B. 1996. Vaccination against tuberculosis by DNA injection. Nat. Med. 2:888.
24. Silva, C. L., Silva, M. F., Pietro, R. C. L. R. and Lowrie, D. B. 1994. A single mycobacterial protein (hsp65) expressed by a transgenic antigen-presenting cell vaccinates mice against tuberculosis. Immunology 82:244.
25. Silva, C. L., Silvo, M. F., Pietro, R. C. L. R. and Lowrie, D. B. 1996. Characterisation of T cells that confer a high degree of protective immunity against tuberculosis in mice after vaccination with tumour cells expressing mycobacterial hsp65. Infect. Immun. 64:2400.
26. Huygen, K., Content, J., Olivier, D., Montgomery, D. L., Yawman, A. M., Deck, R. R., De Witt, C. M., Orme, I. M., Baldwin, S., D'Souza, C., Drowart, A., Lozes, E., Vandenbussche, P., Van Vooren, J.-P., Liu, M. A. and Ulmer, J. B. 1996. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine. Nat. Med. 2:893.
27. Zhu, X., Venkataprasad, N., Thangaraj, H., Hill, M., Singh, M., Ivanyi, J. and Vordermeier, H. M. 1997. Functions and specificity of T cells following nucleic acid vaccination of mice against M. tuberculosis infection. J. Immunol. 158:5921 .
28. Ulmer, J. B., Deck, R. R., Dewitt, J. J., Donelly, C. M. and Liu, M. A. 1996. Generation of MHC class I restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: antigen presentation by non-muscle cells. Immunology 89:59.
29. Doe, B., Selby, M., Barnett, S., Baenzinger, J. and Walker, C. M. 1996. Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells. Proc. Natl Acad. Sci. USA 93:8578
30. Corr, M., Lee, D. J., Carson, D. A. and Tighe, H. 1996. Gene vaccination with naked plasmid DNA: mechanism of CTL priming. J. Exp. Med. 184:1555.
31. Rock, K. L., Gamble, S. and Rothstein, L. 1990. Presentation of exogenous antigen with class I major histocompatibility complex molecules. Science 249:918.
32. Clemens, D. L. and Horwitz, M. A. 1995. Characterisation of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited. J. Exp. Med. 181:257.
33. Sturgill-Koszycki, S., Schlesinger, P., Charkroborty, P., Haddix, P., Collins, H., Fok, A., Allen, R., Gluck, S., Heuser, J. and Russell, D. 1994. Lack of acidification in Mycobacterium phagosomes produced by exclusion of vesicular proton-ATPase. Science 263:678.
34. Mazzaccaro, R. J., Gedde, M., Jensen, E. R., van Santen, H. M., Ploegh, H. L., Rock, K. L. and Bloom, B. R. 1996. Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection. Proc. Natl Acad. Sci. USA 93:11786.
35. Xu, S., Cooper, A., Sturgill-Koszycki, S., Van Heyningen, T., Chatterjee, D., Orme, I., Allen, P. and Russell, D. G. 1994. Intracellular trafficking in Mycobacterium tuberculosis and Mycobacterium avium-infected macrophages. J. Immunol. 153:2568.
36. Russell, D. G., Dant, J. and Sturgill-Koszycki, S. 1996. Mycobacterium avium and Mycobacterium tuberculosis containing vacuoles are dynamic, fusion-competent vesicles that are accessible to glycosphingolipids from the host cell plasmalemma. J. Immunol. 156:4764.
37. Kovacsovics-Bankowski, M. and Rock, K. L. 1995. Aphagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science 267:243.
38. Pfeifer, J. D., Wick, M. J., Roberts, R. L., Findlay, K., Normark, S. J. and Harding, C. V. 1993. Phagocytic processing of bacterial antigens for Class I MHC presentation to T cells. Nature 361:359.
39. Gercken, J., Pryjma, J., Ernst, M. and Flad, H. D. 1994. Defective antigen presentation by Mycobacterium tuberculosis-infected monocytes. Infect. Immun. 62:3472.
40. + T cells of mycobacteria growing in human macrophages. Science 260:984.
41. Mandelboim, O., Berke, G., Fridkin, M., Feldman, M., Eisenstein, M. and Eisenbach, L. 1994. CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma. Nature 369:67.
42. + T cells specific for a single nonamer epitope of Listeria monocytogenes are protective in vivo. J. Exp. Med. 175:1531.
43. Cooper, A. M., Dalton, D. K., Stewart, T. A., Griffin, J. P., Russell, D. G. and Orme, I. M. 1993. Disseminated tuberculosis in interferon-gamma gene-disrupted mice. J. Exp. Med. 178:2243.
44. Flynn, J. L., Chan, J., Triebold, K. J., Dalton, D. K., Stewart, T. A. and Bloom, B. R. 1993. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178:2249.
45. Ciernik, I. F., Berzofsky, J. A. and Carbone, D. P. 1996. Induction of cytotoxic T lymphocytes and antitumor immunity with DNA vaccines expressing single T cell epitopes. J. Immunol. 156:2369.
46. An, L. L., Pamer, E. and Whitton, J. L. 1996. A recombinant minigene vaccine containing a nonameric cytotoxic-T-lymphocyte epitope confers limited protection against Listeria monocytogenes infection. Infect. Immun. 64:1685.
47. An, L. L. and Whitton, J. L. 1997. A multivalent minigene vaccine, containing B-cell, cytotoxic T-lymphocyte and Th epitopes from several microbes induces appropriate responses in vivo and confers protection against more than one pathogen. J. Virol. 71:2292 .
48. Vordermeier, H. M. 1995. T cell recognition of mycobacterial antigens. Eur. Resp. J. 8 (Suppl. 20):657s.
49. Oldstone, M. B. A., Tishon, A., Geckeler, R., Lewicki, H. and Whitton, J. L. 1992. A common antiviral cytotoxic T-lymphocyte epitope for diverse major histocompatibility complex haplotypes: implication for vaccination. Proc. Natl Acad. Sci. USA 89:2752.
50. Shirai, M., Pendleton, C. D. and Berzofsky, J. A. 1992. Broad recognition of cytotoxic T cell epitopes from the HIV-1 envelope protein with multiple class I histocompatibility molecules. J. Immunol. 148:1657.
51. Sidney, J., Grey, H. M., Kubo, R. T. and Sette, A. 1996. Practical, biochemical and evolutionary implications of the discovery of HLA class I supermotifs, Immunol. Today 17:261.