메뉴 건너뛰기




Volumn 16, Issue 5, 1998, Pages 391-401

NGF but not GDNF or neurturin enhance acetylcholine tissue levels in striatal organotypic brain slices

Author keywords

Acetylcholine; GDNF; Growth factor; Neurturin; NGF; Striatum; Survival; Trophic

Indexed keywords

ACETYLCHOLINE; CHOLINE ACETYLTRANSFERASE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; MUSCARINIC M2 RECEPTOR; NERVE GROWTH FACTOR;

EID: 0031740344     PISSN: 07365748     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-5748(98)00039-2     Document Type: Article
Times cited : (15)

References (59)
  • 1
    • 0027165364 scopus 로고
    • Nerve growth factor: A tale of two receptors
    • Barbacid M. (1993) Nerve growth factor: a tale of two receptors. Oncogene 8, 2033-2042.
    • (1993) Oncogene , vol.8 , pp. 2033-2042
    • Barbacid, M.1
  • 2
    • 0025524602 scopus 로고
    • The nerve growth factor family
    • Barde Y. A. (1990) The nerve growth factor family. Progr. Growth Factor Res. 2, 237-248.
    • (1990) Progr. Growth Factor Res. , vol.2 , pp. 237-248
    • Barde, Y.A.1
  • 4
    • 0002413552 scopus 로고
    • A role for nerve growth factors in nervous, endocrine and immune systems
    • Levi-Montalcini R., Aloe L. and Alleva E. (1990) A role for nerve growth factors in nervous, endocrine and immune systems. Prog. Neuroendocrinol. 3, 1-10.
    • (1990) Prog. Neuroendocrinol. , vol.3 , pp. 1-10
    • Levi-Montalcini, R.1    Aloe, L.2    Alleva, E.3
  • 7
    • 0019071287 scopus 로고
    • Physiology of nerve growth factor
    • Thoenen H. and Barde Y.-A. (1980) Physiology of nerve growth factor. Physiol. Rev. 60, 1284-1335.
    • (1980) Physiol. Rev. , vol.60 , pp. 1284-1335
    • Thoenen, H.1    Barde, Y.-A.2
  • 8
    • 0027196324 scopus 로고
    • Functional consequences of a single nerve growth factor administration following septal damage in rats
    • Pallage V., Knusel B., Hefti F. and Will B. (1993) Functional consequences of a single nerve growth factor administration following septal damage in rats. Eur. J. Neurosci. 5, 669-679.
    • (1993) Eur. J. Neurosci. , vol.5 , pp. 669-679
    • Pallage, V.1    Knusel, B.2    Hefti, F.3    Will, B.4
  • 9
    • 0028343937 scopus 로고
    • Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons
    • Winn S. R., Hammang J. P., Emerich D. F., Lee A., Palmiter R. D. and Baetge E. E. (1994) Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons. Proc. Natl. Acad. Sci. U.S.A. 91, 2324-2328.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 2324-2328
    • Winn, S.R.1    Hammang, J.P.2    Emerich, D.F.3    Lee, A.4    Palmiter, R.D.5    Baetge, E.E.6
  • 10
    • 0025765059 scopus 로고
    • Effect of nerve growth factor on the lesioned septohippocampal cholinergic system of aged rats
    • Yunshao H., Zhibin Y. and Yici C. (1991) Effect of nerve growth factor on the lesioned septohippocampal cholinergic system of aged rats. Brain Res. 552, 159-163.
    • (1991) Brain Res. , vol.552 , pp. 159-163
    • Yunshao, H.1    Zhibin, Y.2    Yici, C.3
  • 11
    • 0029655656 scopus 로고    scopus 로고
    • Nerve growth factor withdrawal induces the apoptotic death of developing septal cholinergic neurons in vitro: Protection by cyclic AMP analogue and high potassium
    • Kew J. N. C., Smith D. W. and Sofroniew M. V. (1996) Nerve growth factor withdrawal induces the apoptotic death of developing septal cholinergic neurons in vitro: protection by cyclic AMP analogue and high potassium. Neurosci. 70, 329-339.
    • (1996) Neurosci. , vol.70 , pp. 329-339
    • Kew, J.N.C.1    Smith, D.W.2    Sofroniew, M.V.3
  • 13
    • 0021972462 scopus 로고
    • Choline acetyltransferase activity in striatum of neonatal rats is increased by nerve growth factor
    • Mobley W. C., Rutkowski J. L., Tennekoon G. I., Buchanan K. and Johnston M. V. (1985) Choline acetyltransferase activity in striatum of neonatal rats is increased by nerve growth factor. Science 229, 284-287.
    • (1985) Science , vol.229 , pp. 284-287
    • Mobley, W.C.1    Rutkowski, J.L.2    Tennekoon, G.I.3    Buchanan, K.4    Johnston, M.V.5
  • 14
    • 0024995462 scopus 로고
    • Exogenous nerve growth factor increases the activity of high-affinity choline uptake and choline acetyltransferase in brain of Fisher 344 male rats
    • Williams L. R. and Rylett R. L. (1990) Exogenous nerve growth factor increases the activity of high-affinity choline uptake and choline acetyltransferase in brain of Fisher 344 male rats. J. Neurochem. 55, 1042-1049.
    • (1990) J. Neurochem. , vol.55 , pp. 1042-1049
    • Williams, L.R.1    Rylett, R.L.2
  • 15
    • 0030070458 scopus 로고    scopus 로고
    • The survival of striatal cholinergic neurons cultured from postnatal 2-week-old rats is promoted by neurotrophins
    • Abiru Y., Nishio C. and Hatanaka H. (1996) The survival of striatal cholinergic neurons cultured from postnatal 2-week-old rats is promoted by neurotrophins. Dev. Brain Res. 91, 260-267.
    • (1996) Dev. Brain Res. , vol.91 , pp. 260-267
    • Abiru, Y.1    Nishio, C.2    Hatanaka, H.3
  • 16
    • 0028040044 scopus 로고
    • NGF increases neuritic complexity of cholinergic interneurons in organotypic cultures of neonatal rat striatum
    • Studer L., Spenger C., Luthman J. and Seiler R. W. (1994) NGF increases neuritic complexity of cholinergic interneurons in organotypic cultures of neonatal rat striatum. J. Comp. Neurol. 340, 281-296.
    • (1994) J. Comp. Neurol. , vol.340 , pp. 281-296
    • Studer, L.1    Spenger, C.2    Luthman, J.3    Seiler, R.W.4
  • 17
    • 0029742145 scopus 로고    scopus 로고
    • Chronic infusion of nerve growth factor into rat striatum increases cholinergic markers and inhibits striatal neuronal discharge rate
    • Förander P., Söderström S., Humpel C. and Strömberg I. (1996) Chronic infusion of nerve growth factor into rat striatum increases cholinergic markers and inhibits striatal neuronal discharge rate. European Journal Neuroscience 8, 1822-1832.
    • (1996) European Journal Neuroscience , vol.8 , pp. 1822-1832
    • Förander, P.1    Söderström, S.2    Humpel, C.3    Strömberg, I.4
  • 18
    • 0001641539 scopus 로고
    • Continuous infusion of nerve growth factor prevents basal forebrain neuronal cell death after fimbria fornix transection
    • Williams L., Varon S., Peterson G., Wictorin K., Fischer W., Björklund A. and Gage F. (1986) Continuous infusion of nerve growth factor prevents basal forebrain neuronal cell death after fimbria fornix transection. Proc. Natl. Acad. Sci U.S.A. 83, 9231-9235.
    • (1986) Proc. Natl. Acad. Sci U.S.A. , vol.83 , pp. 9231-9235
    • Williams, L.1    Varon, S.2    Peterson, G.3    Wictorin, K.4    Fischer, W.5    Björklund, A.6    Gage, F.7
  • 19
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin L. F. H., Doherty D. H., Lile J. D., Bektesh S. and Collins F. (1993) GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260, 1130-1132.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.H.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 20
    • 0027731592 scopus 로고
    • Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo
    • Strömberg I., Björklund L., Johansson M., Tomac A., Collins F., Olson L., Hoffer B. and Humpel C. (1993) Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo. Exp. Neurol. 124, 401-412.
    • (1993) Exp. Neurol. , vol.124 , pp. 401-412
    • Strömberg, I.1    Björklund, L.2    Johansson, M.3    Tomac, A.4    Collins, F.5    Olson, L.6    Hoffer, B.7    Humpel, C.8
  • 22
    • 0028912424 scopus 로고
    • Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat
    • Choi-Lundberg D. L. and Bohn M. C. (1995) Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat. Dev. Brain Res. 85, 80-88.
    • (1995) Dev. Brain Res. , vol.85 , pp. 80-88
    • Choi-Lundberg, D.L.1    Bohn, M.C.2
  • 23
    • 0027730253 scopus 로고
    • Regional and cell-specific expression of GDNF in rat brain
    • Schaar D. G., Sieber B.-A., Dreyfus C. F. and Black I. B. (1993) Regional and cell-specific expression of GDNF in rat brain. Exp. Neurol. 124, 368-371.
    • (1993) Exp. Neurol. , vol.124 , pp. 368-371
    • Schaar, D.G.1    Sieber, B.-A.2    Dreyfus, C.F.3    Black, I.B.4
  • 24
    • 0029114190 scopus 로고
    • Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult
    • Tomac A., Widenfalk J., Lin L. F. H., Kohno T., Ebendal T., Hoffer B. and Olson L. (1995) Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proc. Natl. Acad. Sci. U.S.A. 92, 8274-8278.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 8274-8278
    • Tomac, A.1    Widenfalk, J.2    Lin, L.F.H.3    Kohno, T.4    Ebendal, T.5    Hoffer, B.6    Olson, L.7
  • 25
    • 0021176141 scopus 로고
    • Use of central neuronal cultures for the detection of neuronotrophic agents
    • Barbin G., Selak I., Manthorpe M. and Varon S. (1984) Use of central neuronal cultures for the detection of neuronotrophic agents. Neurosci. 12, 33-43.
    • (1984) Neurosci. , vol.12 , pp. 33-43
    • Barbin, G.1    Selak, I.2    Manthorpe, M.3    Varon, S.4
  • 27
    • 0028874203 scopus 로고
    • GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo
    • Kearns C. M. and Gash D. M. (1995) GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo. Brain Res. 672, 104-111.
    • (1995) Brain Res. , vol.672 , pp. 104-111
    • Kearns, C.M.1    Gash, D.M.2
  • 28
  • 29
    • 0028854836 scopus 로고
    • In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
    • Yan Q., Matheson C. and Lopez O. T. (1995) In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373, 341-344.
    • (1995) Nature , vol.373 , pp. 341-344
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3
  • 30
    • 0029584686 scopus 로고
    • GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo
    • Arenas E., Trupp M., Akerud P. and Ibanez C. F. (1995) GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo. Neuron 15, 1465-1473.
    • (1995) Neuron , vol.15 , pp. 1465-1473
    • Arenas, E.1    Trupp, M.2    Akerud, P.3    Ibanez, C.F.4
  • 31
    • 0030437247 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor sustains axotomized basal forebrain cholinergic neurons in vivo: Dose-response comparison to nerve growth factor and brain-derived neurotrophic factor
    • Williams L. R., Inouye G., Cummins V. and Pelleymounter M. A. (1996) Glial cell line-derived neurotrophic factor sustains axotomized basal forebrain cholinergic neurons in vivo: dose-response comparison to nerve growth factor and brain-derived neurotrophic factor. J. Pharmacol. Exp. Ther. 277, 1140-1151.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 1140-1151
    • Williams, L.R.1    Inouye, G.2    Cummins, V.3    Pelleymounter, M.A.4
  • 32
    • 0029827443 scopus 로고    scopus 로고
    • Glial-cell-line-derived neurotrophic factor enhances biosynthesis of substance P in striatal neurons in vitro
    • Humpel C., Marksteiner J. and Saria A. (1996) Glial-cell-line-derived neurotrophic factor enhances biosynthesis of substance P in striatal neurons in vitro. Cell Tissue Res. 286, 249-255.
    • (1996) Cell Tissue Res. , vol.286 , pp. 249-255
    • Humpel, C.1    Marksteiner, J.2    Saria, A.3
  • 33
    • 0030916683 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor protects against ischemia-induced injury in the cerebral cortex
    • Wang Y., Lin S.-Z., Chiou A.-L., Williams L. R. and Hoffer B. J. (1997) Glial cell line-derived neurotrophic factor protects against ischemia-induced injury in the cerebral cortex. J. Neurosci. 17, 4341-4348.
    • (1997) J. Neurosci. , vol.17 , pp. 4341-4348
    • Wang, Y.1    Lin, S.-Z.2    Chiou, A.-L.3    Williams, L.R.4    Hoffer, B.J.5
  • 35
    • 0029655872 scopus 로고    scopus 로고
    • Acute and chronic noradrenergic regulation of neurotrophin messenger RNA expression in rat hippocampus: Evidence from lesions and organotypic cultures
    • Hutter P., Johansson M., Saria A. and Humpel C. (1996) Acute and chronic noradrenergic regulation of neurotrophin messenger RNA expression in rat hippocampus: evidence from lesions and organotypic cultures. Neuroscience 70, 15-29.
    • (1996) Neuroscience , vol.70 , pp. 15-29
    • Hutter, P.1    Johansson, M.2    Saria, A.3    Humpel, C.4
  • 36
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini L., Buchs P. A. and Muller D. (1991) A simple method for organotypic cultures of nervous tissue. J. Neurosci. Meth. 37, 173-182.
    • (1991) J. Neurosci. Meth. , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 37
    • 0000023818 scopus 로고
    • Determination of acetylcholine and choline in the femtomol range by means of HPLC, a postcolumn enzyme reactor and electrochemical detection
    • Damsma G., Lammerts van Eueren D., Westerink B. H. C. and Horn A. S. (1987) Determination of acetylcholine and choline in the femtomol range by means of HPLC, a postcolumn enzyme reactor and electrochemical detection. Chromatographia 24, 827-831.
    • (1987) Chromatographia , vol.24 , pp. 827-831
    • Damsma, G.1    Van Lammerts Eueren, D.2    Westerink, B.H.C.3    Horn, A.S.4
  • 38
    • 0026652985 scopus 로고
    • Release of endogenous acetylcholine in the hypothalamus of conscious rats
    • Prast H. and Philippu A. (1992) Release of endogenous acetylcholine in the hypothalamus of conscious rats. Naunyn-Schmiedeberg's Arch. Pharmacol. 346, 1-3.
    • (1992) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.346 , pp. 1-3
    • Prast, H.1    Philippu, A.2
  • 39
    • 0024405218 scopus 로고
    • Complete sequence of a cDNA encoding an active rat choline acetyltransferase: A tool to investigate the plasticity of cholinergic phenotype expression
    • Brice A., Berrard S., Raynaud B., Ansieau S., Coppola T., Weber M. J. and Mallet J. (1989) Complete sequence of a cDNA encoding an active rat choline acetyltransferase: a tool to investigate the plasticity of cholinergic phenotype expression. J. Neurosci. Res. 23, 266-273.
    • (1989) J. Neurosci. Res. , vol.23 , pp. 266-273
    • Brice, A.1    Berrard, S.2    Raynaud, B.3    Ansieau, S.4    Coppola, T.5    Weber, M.J.6    Mallet, J.7
  • 40
    • 0026756764 scopus 로고
    • Phenotypic characterization of the striatal neurons expressing muscarinic receptor genes
    • Bernard V., Normand E. and Bloch B. (1992) Phenotypic characterization of the striatal neurons expressing muscarinic receptor genes. J. Neurosci. 12, 3591-3600.
    • (1992) J. Neurosci. , vol.12 , pp. 3591-3600
    • Bernard, V.1    Normand, E.2    Bloch, B.3
  • 41
    • 0025130727 scopus 로고
    • Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia
    • Weiner D. M., Levey A. I. and Brann M. R. (1990) Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia. Proc. Natl. Acad. Sci. 87, 7050-7054.
    • (1990) Proc. Natl. Acad. Sci. , vol.87 , pp. 7050-7054
    • Weiner, D.M.1    Levey, A.I.2    Brann, M.R.3
  • 42
    • 0022363496 scopus 로고
    • Immunoaffinity purification of human choline acetyltransferase: Comparison of the brain and placental enzymes
    • Bruce G., Wainer B. H. and Hersh L. B. (1985) Immunoaffinity purification of human choline acetyltransferase: comparison of the brain and placental enzymes. J. Neurochem. 45, 611-620.
    • (1985) J. Neurochem. , vol.45 , pp. 611-620
    • Bruce, G.1    Wainer, B.H.2    Hersh, L.B.3
  • 43
    • 2142704230 scopus 로고    scopus 로고
    • Effects of donor age and brain-derived neurotrophic factor on the survival of dopaminergic neurons and axonal growth in postnatal rat nigrostriatal cocultures
    • Ostergaard K., Jones S. A., Hyman C. and Zimmer J. (1996) Effects of donor age and brain-derived neurotrophic factor on the survival of dopaminergic neurons and axonal growth in postnatal rat nigrostriatal cocultures. Exp. Neurol. 142, 340-350.
    • (1996) Exp. Neurol. , vol.142 , pp. 340-350
    • Ostergaard, K.1    Jones, S.A.2    Hyman, C.3    Zimmer, J.4
  • 44
    • 0027464906 scopus 로고
    • Organotypic slice cultures of rat striatum - I. a histochemical and immunohistochemical study of acetylcholinesterase, choline acetyltransferase, glutamate decarboxylase and GABA
    • Ostergaard K. (1993) Organotypic slice cultures of rat striatum - I. A histochemical and immunohistochemical study of acetylcholinesterase, choline acetyltransferase, glutamate decarboxylase and GABA. Neurosci. 53, 679-693.
    • (1993) Neurosci. , vol.53 , pp. 679-693
    • Ostergaard, K.1
  • 45
    • 0028967199 scopus 로고
    • Organotypic slice cultures of the rat striatum: An immunocytochemical, histochemical and in situ hybridization study of somatostatin, neuropeptide Y, nicotinamide adenine dinucleotide phosphate-diaphorase and enkephalin
    • Ostergaard K., Finsen B. and Zimmer J. (1995) Organotypic slice cultures of the rat striatum: an immunocytochemical, histochemical and in situ hybridization study of somatostatin, neuropeptide Y, nicotinamide adenine dinucleotide phosphate-diaphorase and enkephalin. Exp. Brain Res. 103, 70-84.
    • (1995) Exp. Brain Res. , vol.103 , pp. 70-84
    • Ostergaard, K.1    Finsen, B.2    Zimmer, J.3
  • 46
    • 0028921367 scopus 로고
    • Dopaminergic regulation of transcription factor expression in organotypic cultures of developing striatum
    • Liu F.-C., Takahashi H., McKay R. D. G. and Graybiel A. M. (1995) Dopaminergic regulation of transcription factor expression in organotypic cultures of developing striatum. J. Neurosci. 15, 2367-2384.
    • (1995) J. Neurosci. , vol.15 , pp. 2367-2384
    • Liu, F.-C.1    Takahashi, H.2    McKay, R.D.G.3    Graybiel, A.M.4
  • 47
    • 0027256011 scopus 로고
    • High affinity nerve growth factor receptor (trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brain
    • Steininger T. L., Wainer B. H., Klein R., Barbacid M. and Palfrey H. C. (1993) High affinity nerve growth factor receptor (trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brain. Brain Res. 612, 330-335.
    • (1993) Brain Res. , vol.612 , pp. 330-335
    • Steininger, T.L.1    Wainer, B.H.2    Klein, R.3    Barbacid, M.4    Palfrey, H.C.5
  • 48
    • 0344403376 scopus 로고    scopus 로고
    • High level of protein expression achieved by mRNA transfection in cultured neurons and in brain in vivo
    • Kariko K., Barnathan E. S., Lee V. M. Y., Rangel Y., Langer D. J. and Welsh F. A. (1997) High level of protein expression achieved by mRNA transfection in cultured neurons and in brain in vivo. Society Neurosci. 23, 142.6.
    • (1997) Society Neurosci. , vol.23 , pp. 1426
    • Kariko, K.1    Barnathan, E.S.2    Lee, V.M.Y.3    Rangel, Y.4    Langer, D.J.5    Welsh, F.A.6
  • 49
    • 0030807925 scopus 로고    scopus 로고
    • Neurturin and glial cell line-derived neurotrophic factor receptor-beta (GDNFR-beta), novel proteins related to GDNF and GDNFR-alpha with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in peripheral organs
    • Widenfalk J., Nosrat C., Tomac A., Westphal H., Hoffer B. and Olson L. (1997) Neurturin and glial cell line-derived neurotrophic factor receptor-beta (GDNFR-beta), novel proteins related to GDNF and GDNFR-alpha with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in peripheral organs. J. Neurosci. 17, 8506-8519.
    • (1997) J. Neurosci. , vol.17 , pp. 8506-8519
    • Widenfalk, J.1    Nosrat, C.2    Tomac, A.3    Westphal, H.4    Hoffer, B.5    Olson, L.6
  • 50
    • 0028800803 scopus 로고
    • The neurotrophins BDNF, NT-3, and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro
    • Ventimiglia, R., Mather, P. E., Jones, B. E. and Lindsay, R. M. (1995) The neurotrophins BDNF, NT-3, and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro. Eur. J. Neurosci., 7.
    • (1995) Eur. J. Neurosci. , vol.7
    • Ventimiglia, R.1    Mather, P.E.2    Jones, B.E.3    Lindsay, R.M.4
  • 51
    • 0029920026 scopus 로고    scopus 로고
    • Cell density increases bcl-2 and bcl-x expression in addition to survival of cultured cerebellar granule neurons
    • Ohga Y., Zirrgiebel U., Hamner S., Michaelidis T. M., Cooper J., Thoenen H. and Lindholm D. (1996) Cell density increases bcl-2 and bcl-x expression in addition to survival of cultured cerebellar granule neurons. Neurosci. 73, 913-917.
    • (1996) Neurosci. , vol.73 , pp. 913-917
    • Ohga, Y.1    Zirrgiebel, U.2    Hamner, S.3    Michaelidis, T.M.4    Cooper, J.5    Thoenen, H.6    Lindholm, D.7
  • 52
    • 0030892073 scopus 로고    scopus 로고
    • Protective effects of neurotrophin-4/5 and transforming growth factor-alpha on striatal neuronal phenotypic degeneration after excitotoxic lesioning with quinolinic acid
    • Alexi T., Venero J. L. and Hefti F. (1997) Protective effects of neurotrophin-4/5 and transforming growth factor-alpha on striatal neuronal phenotypic degeneration after excitotoxic lesioning with quinolinic acid. Neurosci. 78, 73-86.
    • (1997) Neurosci. , vol.78 , pp. 73-86
    • Alexi, T.1    Venero, J.L.2    Hefti, F.3
  • 53
    • 0027457774 scopus 로고
    • Localization of bFGF and FGF-receptor in the developing nervous system of the embryonic and newborn rat
    • Weise B., Janet T. and Grothe C. (1993) Localization of bFGF and FGF-receptor in the developing nervous system of the embryonic and newborn rat. J. Neurosci. Res. 34, 442-453.
    • (1993) J. Neurosci. Res. , vol.34 , pp. 442-453
    • Weise, B.1    Janet, T.2    Grothe, C.3
  • 54
    • 0023719528 scopus 로고
    • Basic and acidic fibroblast growth factors have trophic effects on neurons from multiple CNS regions
    • Walicke P. A. (1988) Basic and acidic fibroblast growth factors have trophic effects on neurons from multiple CNS regions. J. Neurosci. 8, 2618-2627.
    • (1988) J. Neurosci. , vol.8 , pp. 2618-2627
    • Walicke, P.A.1
  • 55
    • 0026010614 scopus 로고
    • Localization of insulin-like growth factor I (IGF-I)-like immunoreactivity in the developing and adult rat brain
    • Garcia-Segura L. M., Perez J., Pons S., Rejas M. T. and Torres-Aleman I. (1991) Localization of insulin-like growth factor I (IGF-I)-like immunoreactivity in the developing and adult rat brain. Brain Res. 560, 167-174.
    • (1991) Brain Res. , vol.560 , pp. 167-174
    • Garcia-Segura, L.M.1    Perez, J.2    Pons, S.3    Rejas, M.T.4    Torres-Aleman, I.5
  • 58
    • 0028109526 scopus 로고
    • Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo
    • Hoffer B. J., Hoffman A., Bowenkamp K., Huettl P., Hudson J., Martin D., Lin L.-F. H. and Gerhardt G. (1994) Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. Neurosci. Lett. 182, 107-111.
    • (1994) Neurosci. Lett. , vol.182 , pp. 107-111
    • Hoffer, B.J.1    Hoffman, A.2    Bowenkamp, K.3    Huettl, P.4    Hudson, J.5    Martin, D.6    Lin, L.-F.H.7    Gerhardt, G.8
  • 59
    • 0028981289 scopus 로고
    • Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells
    • Mount H. T. J., Dean D. O., Alberch J., Dreyfus C. F. and Black I. B. (1995) Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. Proc. Natl. Acad. Sci. U.S.A. 92, 9092-9096.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 9092-9096
    • Mount, H.T.J.1    Dean, D.O.2    Alberch, J.3    Dreyfus, C.F.4    Black, I.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.