Synthesis and structure-activity data of some new epibatidine analogues

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 11, 1998, Pages 2103-2110

  Seerden, Jean Paul G ^a   Tulp, Martin Th M ^b   Scheeren, Hans W ^a   Kruse, Chris G ^b  

^a NSR Center   (Netherlands)

^b Solvay Pharmaceuticals Inc   (Netherlands)

Author keywords

Epibatidine analogues; High pressure; Hydroarylation; Structure activity data

Indexed keywords

ALKALOID; EPIBATIDINE; EPIBATIDINE DERIVATIVE; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN TISSUE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; STRUCTURE ACTIVITY RELATION;

ALKALOIDS; ANIMALS; AZOCINES; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING, COMPETITIVE; BRAIN; CELL MEMBRANE; DRUG DESIGN; INDICATORS AND REAGENTS; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NICOTINIC AGONISTS; PYRIDINES; QUINOLIZINES; RATS; RECEPTORS, NICOTINIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031739373     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00163-1     Document Type: Article

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