Three-dimensional structures of the cysteine proteases cathepsins K and S deduced by knowledge-based modelling and active site characteristics

Protein Engineering

Volumn 11, Issue 11, 1998, Pages 1007-1013

  Fengler, Annett ^a   Brandt, Wolfgang ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Cathepsins K and S; COMPOSER; Molecular modelling; Tertiary structure

Indexed keywords

CATHEPSIN; CATHEPSIN S; CYSTEINE PROTEINASE; ENZYME INHIBITOR; PAPAIN;

ARTICLE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME INHIBITOR COMPLEX; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN TERTIARY STRUCTURE;

EID: 0031736958     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/11.11.1007     Document Type: Article

References (44)

1. Aibe, K., Yazawa, H., Abe, K., Teramura, K., Kumegawa, M., Kawashima, H. and Honda, K. (1996) Biol. Pharm. Bull., 19, 1026-1031.
2. Barrett, A.J. and Kirschke, H. (1981) Methods Enzymol., 80, 535-561.
3. Blondeau, X., Vidmar, S.L., Emod, I., Pagano, M., Turk, V. and Keil-Dlouha, V. (1993) Biol. Chem. Hoppe-Seyler, 374, 651-656.
4. Blundell, T.L., Carney, D., Gardner, S., Hayes, F., Howlin, B., Hubbard, T., Overington, J., Singh, D.A., Sibanda, B.L. and Sutcliffe, M. (1988) Eur. J. Biochem., 172, 513-520.
5. Bond, J.S. and Barrett, A.J. (1980) Biochem. J., 189, 17-25.
6. Bossard, M.J., Tomaszek, A.T., Thompson, S.K., Amegadzie, B.Y., Hanning, C.R., Jones, C., Kurdyla, J.T., McNulty, D.E., Drake, F.H., Gowen, M. and Levy, M.A. (1996) J. Biol. Chem., 271, 12517-12524.
7. Brömme, D. and McGrath, M.E. (1996) Protein Sci., 5, 789-791.
8. Brömme, D. and Okamoto, K. (1995) Biol. Chem. Hoppe-Seyler, 376, 379-384.
9. Brömme, D., Steinert, A., Friebe, S., Fittkau, S., Wiederanders, B. and Kirschke, H. (1989) Biochem. J., 264, 475-481.
10. Brömme, D., Klaus, J.L., Okamoto, K., Rasnick, D. and Palmer, J.T. (1996) Biochem. J., 315, 85-89.
11. Buttle, D.J, Saklatvala, J. and Barrett, A.J. (1992) Agents Actions Suppl., 39, 161-165.
12. Cataldo, A.M., Paskevich, P.A., Kominami, E. and Nixon, R.A. (1991) Proc. Natl Acad. Sci. USA, 88, 10998-11002.
13. Chapman, H.A., Stone, O.L. and Vavrin, Z. (1984) J. Clin. Invest., 73, 806-815.
14. Clark, M., Cramer III,R.D. and Van Opdenbosch, N. (1989) Comput. Chem., 10, 982-1012.
15. Delaisse, J.M., Eeckhout, Y. and Vaes, G. (1980) Biochem. J., 192, 365-368.
16. Drake, F.-H., Dodds,. R., James, I., Connor, J., Debouck, C., Richardson, S., Lee, E., Rieman, D., Barhlow, R., Hastings, G. and Gowen, M. (1996) J. Biol. Chem., 271, 12511-12516.
17. Eeckhout, Y. and Vaes, G. (1977) Biochem. J., 166, 21-31.
18. Eidelmann, D., Saetta, M.P., Ghezzo, H., Wang, N.-S., Hoidal, J.R., King, M. and Cosio, M.G. (1990) Am. Rev. Respir. Dis., 141, 1547-1552.
19. Gabrijelcic, D., Svetic, B., Spaic, D., Skrk, J., Budihna, M., Dolenc, I., Popovic, T., Cotic, V. and Turk, V. (1992) Eur. J. Clin. Chem. Clin. Biochem., 30, 69-74.
20. Gasteiger, J. and Marsili, M. (1980) Tetrahedron, 36, 3219-3238.
21. Guinec, N., Dalet-Fumeron, V. and Pagano, M. (1993) Biol. Chem. Hoppe-Seyler, 374, 1135-1146.
22. Inaoka, T., Bilbe, G., Ishibashi, O., Tezuka, K., Kumagawa, M. and Kokubo, T. (1995) Biochem. Biophys. Res. Commun., 206, 89-96.
23. Judson, R. (1997) In Lipkowitz, K.B. and Boyd, D.B. (eds) Reviews in Computer Chemistry, Vol. 10, VCH Publishers.
24. Kobayashi, H., Schmitt, M., Goretzki, L., Chucholowski, N., Calvete, J., Kramer, M., Gunzaler, W.A., Janicke, F. and Graeff, H. (1991) J. Biol. Chem., 266, 5147-5152.
25. Li, Y.P., Alexander, M.B., Wucherpfennig, A.L., Chen, W., Yelick, P. and Stashenko, P. (1994) Mol. Biol. Cell, 5, 335a-342.
26. Maciewicz, R.A. and Etherington, D.J. (1988) Biochem. J., 256, 433-440.
27. Maciewicz, R.A., Wotton, S.F., Etherington, D.J. and Duance, V.C. (1990) FEBS Lett., 269, 189-193.
28. Mason, R.W., Taylor, M.A. and Etherington, D.J. (1984) Biochem. J., 217, 209-217.
29. Mason, R.W., Green, G.D.J and Barrett, A.J. (1985) Biochem. J., 226, 233-241.
30. McGrath, M.E., Klaus, J.L., Barnes, M.G. and Brömme, D. (1997) Nature Struct. Biol., 4, 105-109.
31. Michalek, M.T., Beancerraf, B. and Rock, K.L. (1992) J. Immunol., 148, 1016-1024.
32. Mort, J.S., Leduc, M.S. and Recklies, A.D. (1983) Biochim. Biophys. Acta, 755, 369-375.
33. Petanceska, S., Burke, S., Watson, S.J. and Devi, L. (1994) Neuroscience, 59, 729-738.
34. Roche, P.A. and Cresswell, P. (1991) Proc. Natl Acad. Sci. USA, 88, 3150-3154.
35. Schamberger, R.J. and Rudolph, G. (1967) Nature, 213, 617-619.
36. Schechter, I. and Berger, A. (1967) Biochem. Biophys. Res. Commun., 27, 157-162.
37. Shi, G.-P., Chapman, H.A., Bhairi, S.M., DeLeeuw, C., Reddy, V.Y. and Weiss, S.J. (1995) FEBS Lett., 357, 129-134.
38. Shinagawa, T., Do, Y.S., Baxter, J.K., Carilli, C., Schilling, J. and Hsueh, W.A. (1990) Proc. Natl Acad. Sci. USA, 87, 1927-1933.
39. Sippl, M.J. (1993a) Proteins, 17, 355-362.
40. Sippl, M.J. (1993b) J. Comp. Aided-Mol. Des., 7, 473-501.
41. Sloane, B.F., Dunn, J.R. and Honn, K.V. (1981) Science, 212, 1151-1153.
42. Takahashi, H., Cease, K.B. and Berzofsky, J.A. (1989) J. Immunol., 142, 2221-2229.
43. Tezuka, K., Tezuka, Y., Maejima, A., Sato, T., Nemoto, K., Kamioka, H., Hakeda, Y. and Kumegawa, M. (1994) J. Biol. Chem., 269, 1106-1109.
44. Uchiyama, Y., Watanabe, T. Watanabe, M., Ishii, I., Matsuba, H., Waguri, S. and Kominami, E. (1989) J. Histochem. Cytochem., 37, 691-696.