Antibody to carbonic anhydrase II is present in primary biliary cirrhosis (PBC) irrespective of antimitochondrial antibody status

Clinical and Experimental Immunology

Volumn 114, Issue 3, 1998, Pages 448-454

  Invernizzi, P ^a,b   Battezzati, P M ^a   Crosignani, A ^a   Zermiani, P ^a   Bignotto, M ^a   Del Papa, N ^a   Zuin, M ^a   Podda, M ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b SAN PAOLO HOSPITAL   (Italy)

Author keywords

Antibody; Antimitochondrial; Autoantibodies; Autoimmune cholangitis; Carbonic anhydrase; Primary biliary cirrhosis

Indexed keywords

CARBONATE DEHYDRATASE II; MITOCHONDRION ANTIBODY;

ADULT; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; CLINICAL FEATURE; FEMALE; HUMAN; IMMUNOBLOTTING; MAJOR CLINICAL STUDY; MALE; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; SERODIAGNOSIS;

ADULT; AUTOANTIBODIES; CARBONIC ANHYDRASES; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; LIVER CIRRHOSIS, BILIARY; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MITOCHONDRIA;

EID: 0031736097     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00735.x     Document Type: Article

References (27)

1. Kaplan MM. Primary biliary cirrhosis. N Engl J Med 1996; 335:1570-80.
2. Ben-Ari Z, Dhillon AP, Sherlock S. Autoimmune cholangiopathy: part of the spectrum of autoimmune chronic active hepatitis. Hepatology 1993; 18:10-5.
3. Michieletti P, Wanless IR, Katz A, Scheuer PJ, Yeaman SJ, Bassendine MF, Palmer JM, Heathcote EJ. Antimitochondrial antibody-negative primary biliary cirrhosis: a distinct syndrome of autoimmune cholangitis. Gut 1994; 35:260-5.
4. Lacerda MA, Ludwig J, Dickson ER, Jorgensen RA, Lindor KD. Antimitochondrial antibody-negative primary biliary cirrhosis. Am J Gastroenterol 1995; 90:247-9.
5. Czaja AJ. The variant forms of autoimmune hepatitis. Ann Intern Med 1996; 125:588-98.
6. Roberts SK, Ludwig J, LaRusso NF. The pathobiology of biliary epithelia. Gastroenterology 1997; 112:269-79.
7. O'Donohue J, Williams R. Antimitochondrial antibody and primary biliary cirrhosis: can there be one without the other? J Hepatol 1996; 25:574-7.
8. Heathcote EJ. Autoimmune cholangitis. Gut 1997; 40:440-2.
9. Invernizzi P, Crosignani A, Battezzati PM, Covini G, De Valle G, Larghi A, Zuin M, Podda M. Comparison of the clinical features and clinical course of antimitochondrial antibody-positive and -negative primary biliary cirrhosis. Hepatology 1997; 25:1090-5.
10. Kim WR, Poterucha JJ, Jorgensen RA et al. Does antimitochondrial antibody status affect response to treatment in patients with primary biliary cirrhosis? Outcomes of ursodeoxycholic acid therapy and liver transplantation. Hepatology 1997; 26:22-26.
11. Gordon SC, Quattrociocchi-Longe TM, Khan BA, Kodali VP, Chen J, Silverman AL, Kiechle FL. Antibodies to carbonic anhydrase in patients with autoimmune cholangitis. Gastroenterology 1995; 108:1802-9.
12. Muratori P, Muratori L, Lenzi M, Bianchi FB. Antibodies to carbonic anhydrase in autoimmune cholangiopathy. Gastroenterology 1997; 112:1053-9.
13. Inagaki Y, Jinno-Yoshida Y, Hamasaki Y, Ueki H. A novel autoantibody reactive with carbonic anhydrase in sera from patients with systemic lupus erythematosus and Sjögren's syndrome. J Dermatol Sci 1991; 2:147-54.
14. Itoh Y, Reichlin M. Antibodies to carbonic anhydrase in systemic lupus erythematosus and other rheumatic diseases. Arthritis Rheum 1992; 35:73-82.
15. Kino-Ohsaki J, Nishimori I, Morita M, Okazaki K, Yamamoto Y, Onishi S, Hollingsworth MA. Serum antibodies to carbonic anhydrase I and II in patients with idiopathic chronic pancreatitis and Sjögren's syndrome. Gastroenterology 1996; 110:1579-86.
16. Tsianos EV, Hoofnagle JH, Fox PC, Alspaugh M, Jones EA, Schafer DF, Moutsopoulos HM. Sjögren's syndrome in patients with primary biliary cirrhosis. Hepatology 1990; 11:730-4.
17. Ludwig J, Dickson ER, McDonald GSA. Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis). Virchows Arch [A] 1978; 379:103-12.
18. Vitali C, Bombardieri S, Moutsopoulos HM, Coll J, Gerli R, Hatron PY and the European Study Group on Diagnostic Criteria for Sjögren's Syndrome. Assessment of the European classification criteria for Sjögren's syndrome in a series of clinically defined cases: results of a prospective nnilticentre study. Ann Rheum Dis 1996; 55:116-21.
19. LeRoy EC, Black C, Fleischmajer R, Jablonska S, Krieg T, Medsger TA Jr, Rowell N, Wollheim F. Scleroderma (systemic sclerosis): classification, subsets, and pathogenesis. J Rheumatol 1988; 15:202-5.
20. Johnson PJ, McFarlane IG. Meeting report: International Autoimmune Hepatitis Group. Hepatol 1993; 18:998-1005.
21. Tan EM, Cohen AS, Fries JF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25:1271-7.
22. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227:680-5.
23. Parkkila S, Parkkila A-K. Carbonic anhydrase in the alimentary tract. Roles of the different isozymes and salivary factors in the maintenance of optimal conditions in the gastrointestinal canal. Scand J Gastroenterol 1996; 31:305-17.
24. Nishimori I, Bratanova T, Toshkov I, Caffrey T, Mogaki M, Shibata Y, Hollingsworth MA. Induction of experimental autoimmune sialoadenitis by immunization of PL/J mice with carbonic anhydrase II. J Immunol 1995; 154:4865-73.
25. Ueno Y, Phillips JO, Ludwig J, Litchman SN, LaRusso NF. Development and characterization of a rodent model of immune-mediated cholangitis. Proc Natl Acad Sci USA 1996; 93:216-20.
26. Epstein O, Thomas HC, Sherlock S. Primary biliary cirrhosis is a 'dry gland' syndrome with features of chronic graft versus host (GvH) disease. Lancet 1980; 1:1166-8.
27. Sly WS, Hu PY. Human carbonic anhydrases and carbonic anhydrase deficiencies. Annu Rev Biochem 1995; 64:375-401.