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Volumn 139, Issue 5, 1998, Pages 2392-2398

Guanosine triphosphatase-activating protein-associated protein, but not src-associated protein p68 in mitosis, is a part of insulin signaling complexes

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTYROSINE; PROTEIN KINASE P60;

EID: 0031734709     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.5.6019     Document Type: Article
Times cited : (8)

References (54)
  • 1
    • 0026652899 scopus 로고
    • Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways
    • Fantl WJ, Escobedo JA, Martin GA, Turck CW, del Rosario M, McCormick F, Williams LT 1992 Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways. Cell 69:413-423
    • (1992) Cell , vol.69 , pp. 413-423
    • Fantl, W.J.1    Escobedo, J.A.2    Martin, G.A.3    Turck, C.W.4    Del Rosario, M.5    McCormick, F.6    Williams, L.T.7
  • 2
    • 0027374488 scopus 로고
    • Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells
    • Yano H, Nakanishi S, Kimura K, Hanai N, Saitoh Y, Fukui Y, Nonomura Y, Matsuda Y 1993 Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem 268:25846-25856
    • (1993) J Biol Chem , vol.268 , pp. 25846-25856
    • Yano, H.1    Nakanishi, S.2    Kimura, K.3    Hanai, N.4    Saitoh, Y.5    Fukui, Y.6    Nonomura, Y.7    Matsuda, Y.8
  • 3
    • 0027939430 scopus 로고
    • Role of phosphatidylinositol-3-kinase in insulin receptor signaling: Studies with inhibitor, LY294002
    • Sanchez-Margalet V, Goldfine ID, Vlahos CJ, Sung CK 1994 Role of phosphatidylinositol-3-kinase in insulin receptor signaling: studies with inhibitor, LY294002. Biochem Biophys Res Commun 204:446-452
    • (1994) Biochem Biophys Res Commun , vol.204 , pp. 446-452
    • Sanchez-Margalet, V.1    Goldfine, I.D.2    Vlahos, C.J.3    Sung, C.K.4
  • 5
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
    • Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR 1994 Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14:4902-4911
    • (1994) Mol Cell Biol , vol.14 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 7
    • 0029973135 scopus 로고    scopus 로고
    • Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes
    • Martin SS, Olefsky JM, Williams LT, Klippel A, Morris AJ, Haruta T 1996 Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes. J Biol Chem 271:17605-17608
    • (1996) J Biol Chem , vol.271 , pp. 17605-17608
    • Martin, S.S.1    Olefsky, J.M.2    Williams, L.T.3    Klippel, A.4    Morris, A.J.5    Haruta, T.6
  • 8
    • 0030059569 scopus 로고    scopus 로고
    • Phosphati-dylinositon-3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells
    • Yang J, Holman G, Kasuga M, Young P, Ester C, Clarke J 1996 Phosphati-dylinositon-3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells. Biochem J 313:125-131
    • (1996) Biochem J , vol.313 , pp. 125-131
    • Yang, J.1    Holman, G.2    Kasuga, M.3    Young, P.4    Ester, C.5    Clarke, J.6
  • 11
    • 0028178428 scopus 로고
    • Direct association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 beta
    • Hu P, Schlessinger J 1994 Direct association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 beta. Mol Cell Biol 14:2577-2583
    • (1994) Mol Cell Biol , vol.14 , pp. 2577-2583
    • Hu, P.1    Schlessinger, J.2
  • 12
    • 0025727594 scopus 로고
    • cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of P13-kinase to the PDGF β-receptor
    • Escobedo J, Navankasattusas S, Kavanaugh W, Milfay D, Fried V, Williams L 1991 cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of P13-kinase to the PDGF β-receptor. Cell 65:75-82
    • (1991) Cell , vol.65 , pp. 75-82
    • Escobedo, J.1    Navankasattusas, S.2    Kavanaugh, W.3    Milfay, D.4    Fried, V.5    Williams, L.6
  • 13
    • 0025921611 scopus 로고
    • Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases
    • Skolnik EY, Margolis B, Mohammadi M, Lowenstein E, Fischer R, Drepps A, Ullrich A, Schlessinger J 1991 Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases. Cell 65:83-90
    • (1991) Cell , vol.65 , pp. 83-90
    • Skolnik, E.Y.1    Margolis, B.2    Mohammadi, M.3    Lowenstein, E.4    Fischer, R.5    Drepps, A.6    Ullrich, A.7    Schlessinger, J.8
  • 15
    • 0025765803 scopus 로고
    • SH2 and SH3 domains: Elements that control interactions of cytoplasmic signaling proteins
    • Koch C, Anderson D, Moran M, Ellis C, Pawson T 1991 SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science 252:668-674
    • (1991) Science , vol.252 , pp. 668-674
    • Koch, C.1    Anderson, D.2    Moran, M.3    Ellis, C.4    Pawson, T.5
  • 16
    • 0027408247 scopus 로고
    • Identification of a ten-amino proline-rich SH3 binding site
    • Ren R, Mayer B, Cicchetti P, Baltimore D 1993 Identification of a ten-amino proline-rich SH3 binding site. Science 259:1157-1161
    • (1993) Science , vol.259 , pp. 1157-1161
    • Ren, R.1    Mayer, B.2    Cicchetti, P.3    Baltimore, D.4
  • 17
    • 0027962645 scopus 로고
    • Two binding orientations for peptides to the Src SH3 domain: Development of a general model for SH3-ligand interactions
    • Feng S, Chen J, Yu H, Simon J, Schreiber S 1994 Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science 266:1241-1247
    • (1994) Science , vol.266 , pp. 1241-1247
    • Feng, S.1    Chen, J.2    Yu, H.3    Simon, J.4    Schreiber, S.5
  • 19
    • 0026340995 scopus 로고
    • Phosphoinositide 3-kinase: A new effector in signal transduction?
    • Downes C, Carter A 1991 Phosphoinositide 3-kinase: a new effector in signal transduction? Cell Sig 3:501-513
    • (1991) Cell Sig , vol.3 , pp. 501-513
    • Downes, C.1    Carter, A.2
  • 20
    • 0028904053 scopus 로고
    • Insulin action and the insulin signaling network
    • Cheatham B, Kahn R 1995 Insulin action and the insulin signaling network. Endocr Rev 16:117-142
    • (1995) Endocr Rev , vol.16 , pp. 117-142
    • Cheatham, B.1    Kahn, R.2
  • 21
    • 0023392635 scopus 로고
    • The insulin receptor: Molecular biology and transmembrane signalling
    • Goldfine ID 1987 The insulin receptor: molecular biology and transmembrane signalling. Endocr Rev 8:235-255
    • (1987) Endocr Rev , vol.8 , pp. 235-255
    • Goldfine, I.D.1
  • 22
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich A, Schlessinger J 1990 Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 23
    • 0022347547 scopus 로고
    • Insulin rapidly stimulates tyrosine phosphorylation of a Mr 185,000 protein in intact cells
    • White M, Maron R, Kahn C 1985 Insulin rapidly stimulates tyrosine phosphorylation of a Mr 185,000 protein in intact cells. Nature 318:183-186
    • (1985) Nature , vol.318 , pp. 183-186
    • White, M.1    Maron, R.2    Kahn, C.3
  • 27
    • 0028012445 scopus 로고
    • Direct activation of the phosphatidylinositol 3′-kinase by the insulin receptor
    • Van Horn D, Myers MJ, Backer J 1994 Direct activation of the phosphatidylinositol 3′-kinase by the insulin receptor. J Biol Chem 269:29-32
    • (1994) J Biol Chem , vol.269 , pp. 29-32
    • Van Horn, D.1    Myers, M.J.2    Backer, J.3
  • 28
    • 0028006743 scopus 로고
    • Insulin-induced activation of phosphatidylinositol 3-kinase: Demonstration that the p85 subunit binds to the COOH terminus of the insulin receptor in intact cells
    • Levy-Toledano R, Taouis M, Blaettler D, Gordon P, Taylor S 1994 Insulin-induced activation of phosphatidylinositol 3-kinase: Demonstration that the p85 subunit binds to the COOH terminus of the insulin receptor in intact cells. J Biol Chem 269:31178-31182
    • (1994) J Biol Chem , vol.269 , pp. 31178-31182
    • Levy-Toledano, R.1    Taouis, M.2    Blaettler, D.3    Gordon, P.4    Taylor, S.5
  • 29
    • 0028967845 scopus 로고
    • Role of p85 Subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor to insulin receptor substrate 1
    • Sanchez-Margalet V, Goldfine I, Truitt K, Imboden J, Sung C 1995 Role of p85 Subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor to insulin receptor substrate 1. Mol Endocrinol 9:435-442
    • (1995) Mol Endocrinol , vol.9 , pp. 435-442
    • Sanchez-Margalet, V.1    Goldfine, I.2    Truitt, K.3    Imboden, J.4    Sung, C.5
  • 31
    • 0027412618 scopus 로고
    • Insulin-stimulated phosphatidylinositol 3-kinase
    • Kelly KL, Ruderman NB 1993 Insulin-stimulated phosphatidylinositol 3-kinase. J Biol Chem 268:4391-4398
    • (1993) J Biol Chem , vol.268 , pp. 4391-4398
    • Kelly, K.L.1    Ruderman, N.B.2
  • 32
    • 0027417484 scopus 로고
    • The insulin-elicited 60-kDa phosphotyrosine protein in rat adipocytes is associated with phosphatidyl inositol 3-kinase
    • Lavan BE, Lienhard GE 1993 The insulin-elicited 60-kDa phosphotyrosine protein in rat adipocytes is associated with phosphatidyl inositol 3-kinase. J Biol Chem 268:5921-5928
    • (1993) J Biol Chem , vol.268 , pp. 5921-5928
    • Lavan, B.E.1    Lienhard, G.E.2
  • 33
    • 0028232158 scopus 로고
    • Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor, p62 and GTPase activating protein
    • Sung C, Sanchez-Margalet V, Goldfine I 1994 Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor, p62 and GTPase activating protein. J Biol Chem 269:12503-12507
    • (1994) J Biol Chem , vol.269 , pp. 12503-12507
    • Sung, C.1    Sanchez-Margalet, V.2    Goldfine, I.3
  • 34
    • 0029995773 scopus 로고    scopus 로고
    • A 60-kilodalton protein in rat hepatoma cells overexpressing insulin receptor was tyrosine phosphorylated and associated with Syp, phosphatidylinositol 3-kinase, and Grb2 in an insulin-dependent manner
    • Zhang-Sun G, Yang C, Viallet J, Feng G, Bergeron J, Posner B 1996 A 60-kilodalton protein in rat hepatoma cells overexpressing insulin receptor was tyrosine phosphorylated and associated with Syp, phosphatidylinositol 3-kinase, and Grb2 in an insulin-dependent manner. Endocrinology 137:2649-2658
    • (1996) Endocrinology , vol.137 , pp. 2649-2658
    • Zhang-Sun, G.1    Yang, C.2    Viallet, J.3    Feng, G.4    Bergeron, J.5    Posner, B.6
  • 35
    • 0028329195 scopus 로고
    • An RNA-binding protein associated with src through its SH2 and SH3 domains in mitosis
    • Taylor S, Shalloway D 1994 An RNA-binding protein associated with src through its SH2 and SH3 domains in mitosis. Nature 368:867-871
    • (1994) Nature , vol.368 , pp. 867-871
    • Taylor, S.1    Shalloway, D.2
  • 37
    • 0026486879 scopus 로고
    • Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85beta protein by using the baculovirus expression system
    • Gout I, Dhand R, Panayotou G, Fry MJ, Hiles I, Otsu M, Waterfield MD 1992 Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85beta protein by using the baculovirus expression system. Biochem J 288:395-405
    • (1992) Biochem J , vol.288 , pp. 395-405
    • Gout, I.1    Dhand, R.2    Panayotou, G.3    Fry, M.J.4    Hiles, I.5    Otsu, M.6    Waterfield, M.D.7
  • 38
    • 0028152517 scopus 로고
    • Regulation by insulin of phosphatidylinositol 3′-kinase bound to alpha and beta-isoforms of p85 regulatory subunit
    • Baltensperger K, Kozma LM, Jaspers SR, Czech MP 1994 Regulation by insulin of phosphatidylinositol 3′-kinase bound to alpha and beta-isoforms of p85 regulatory subunit. J Biol Chem 269:28937-28946
    • (1994) J Biol Chem , vol.269 , pp. 28937-28946
    • Baltensperger, K.1    Kozma, L.M.2    Jaspers, S.R.3    Czech, M.P.4
  • 40
    • 0024844946 scopus 로고
    • Monoclonal antibodies mimic insulin activation of ribosomal protein S6 kinase without activation of insulin receptor tyrosine kinase
    • Sung CK, Maddux BA, Hawley DM, Goldfine ID 1989 Monoclonal antibodies mimic insulin activation of ribosomal protein S6 kinase without activation of insulin receptor tyrosine kinase. J Biol Chem 264:18951-18959
    • (1989) J Biol Chem , vol.264 , pp. 18951-18959
    • Sung, C.K.1    Maddux, B.A.2    Hawley, D.M.3    Goldfine, I.D.4
  • 42
    • 0027212268 scopus 로고
    • The new elements of insulin signaling: Insulin receptor substrate-1 and proteins with SH2 domains
    • Myers Jr M, White M 1993 The new elements of insulin signaling: Insulin receptor substrate-1 and proteins with SH2 domains. Diabetes 42:643-650
    • (1993) Diabetes , vol.42 , pp. 643-650
    • Myers Jr., M.1    White, M.2
  • 43
    • 0026697169 scopus 로고
    • Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62
    • Wong G, Muller O, Clark R, Conroy L, Moran MF, Polakis P, McCormick F 1992 Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62. Cell 69:551-558
    • (1992) Cell , vol.69 , pp. 551-558
    • Wong, G.1    Muller, O.2    Clark, R.3    Conroy, L.4    Moran, M.F.5    Polakis, P.6    McCormick, F.7
  • 44
    • 0030748457 scopus 로고    scopus 로고
    • The insulin signaling system and the 1RS proteins
    • White M 1997 The insulin signaling system and the 1RS proteins. Diabetologia 40:S2-S17
    • (1997) Diabetologia , vol.40
    • White, M.1
  • 46
    • 0027379041 scopus 로고
    • Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinase
    • Chuang LM, Myers Jr MG, Backer JM, Shoelson SE, White MF, Birnbaum MJ, Kahn R 1993 Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinase. Mol. Cell Biol 13:6653-6660
    • (1993) Mol. Cell Biol , vol.13 , pp. 6653-6660
    • Chuang, L.M.1    Myers Jr., M.G.2    Backer, J.M.3    Shoelson, S.E.4    White, M.F.5    Birnbaum, M.J.6    Kahn, R.7
  • 47
    • 0027972094 scopus 로고
    • Evidence for two distinct 60-kilodalton substrates of the SRC tyrosine kinase
    • Ogawa W, Hosomi Y, Shii K, Roth R 1994 Evidence for two distinct 60-kilodalton substrates of the SRC tyrosine kinase. J Biol Chem 269:29602-29608
    • (1994) J Biol Chem , vol.269 , pp. 29602-29608
    • Ogawa, W.1    Hosomi, Y.2    Shii, K.3    Roth, R.4
  • 48
    • 0030995946 scopus 로고    scopus 로고
    • The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family
    • Lavan B, Lane W, Lienhard G 1997 The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family. Journal of Biological Chemistry 272:11439-11443
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 11439-11443
    • Lavan, B.1    Lane, W.2    Lienhard, G.3
  • 49
    • 0030061773 scopus 로고    scopus 로고
    • The human p62 cDNA encodes Sam68 and not the Ras GAP-associated p62 protein
    • Lock P, Fumagalli S, Polakis P, McCormick F, Courtneidge S 1996 The human p62 cDNA encodes Sam68 and not the Ras GAP-associated p62 protein. Cell 84:23-24
    • (1996) Cell , vol.84 , pp. 23-24
    • Lock, P.1    Fumagalli, S.2    Polakis, P.3    McCormick, F.4    Courtneidge, S.5
  • 50
    • 0031444245 scopus 로고    scopus 로고
    • Identification of the Abl- and rasGAP-Associated 62 kDa protein as a docking protein, Dok
    • Yamanashi Y, Baltimore D 1997 Identification of the Abl- and rasGAP-Associated 62 kDa protein as a docking protein, Dok. Cell 88:205-211
    • (1997) Cell , vol.88 , pp. 205-211
    • Yamanashi, Y.1    Baltimore, D.2
  • 51
    • 0031459864 scopus 로고    scopus 로고
    • p62dok: A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells
    • Carpino N, Wisniewski D, Strife A, Marshak D, Kobayashi R, Stillman B, Clarkson B 1997 p62dok: A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell 88:197-204
    • (1997) Cell , vol.88 , pp. 197-204
    • Carpino, N.1    Wisniewski, D.2    Strife, A.3    Marshak, D.4    Kobayashi, R.5    Stillman, B.6    Clarkson, B.7
  • 52
    • 85038548670 scopus 로고    scopus 로고
    • Internalization and recycling of pp120, a substrate of the insulin receptor kinase
    • Abstract 561
    • Choice C, Najjar SM 1996 Internalization and recycling of pp120, a substrate of the insulin receptor kinase. Diabetes 45 (Abstract 561)
    • (1996) Diabetes , vol.45
    • Choice, C.1    Najjar, S.M.2
  • 53
    • 0023227345 scopus 로고
    • Insulin stimulates phosphorylation of a 120 kDa glycoprotein substrate (pp120) for the receptor-associated protein kinase in intact H-35 hepatoma cells
    • Perrotti N, Accili D, Marcus-Samuels B, Rees-Jones R, Taylor S 1987 Insulin stimulates phosphorylation of a 120 kDa glycoprotein substrate (pp120) for the receptor-associated protein kinase in intact H-35 hepatoma cells. Proc Natl Acad Sci USA 84:3137-3140
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 3137-3140
    • Perrotti, N.1    Accili, D.2    Marcus-Samuels, B.3    Rees-Jones, R.4    Taylor, S.5
  • 54
    • 0029045734 scopus 로고
    • Identification of the major SHPTP2-binding protein that is tyrosine phosphorylated in response to insulin
    • Yamauchi K, Ribon V, Saltiel A, Pessin J 1995 Identification of the major SHPTP2-binding protein that is tyrosine phosphorylated in response to insulin. J Biol Chem 270:17716-17722
    • (1995) J Biol Chem , vol.270 , pp. 17716-17722
    • Yamauchi, K.1    Ribon, V.2    Saltiel, A.3    Pessin, J.4


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