A 60-Kilodalton Protein in Rat Hepatoma Cells Overexpressing Insulin Receptor Was Tyrosine Phosphorylated and Associated with Syp, Phosphatidylinositol 3-Kinase, and Grb2 in an Insulin-Dependent Manner

Endocrinology

Volumn 137, Issue 7, 1996, Pages 2649-2658

  Zhang Sun, Guiyi ^a   Yang, Chang Ren ^a   Viallet, Jean ^b   Feng, Gen Sheng ^c   Bergeron, John J M ^a   Posner, Barry I ^a,d  

^a ROYAL VICTORIA HOSPITAL   (Canada)

^b NOTRE DAME HOSPITAL   (Canada)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTYROSINE;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CELL LYSATE; CELL MIGRATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEPATOMA CELL; IMMUNOBLOTTING; INSULIN TREATMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; SEQUENCE HOMOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADIPOSE TISSUE; ANIMALS; BLOTTING, WESTERN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GLUTATHIONE TRANSFERASE; GRB2 ADAPTOR PROTEIN; HUMANS; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MOLECULAR WEIGHT; MUSCLE, SKELETAL; ORGAN SPECIFICITY; PHOSPHOPROTEINS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PHOSPHOTYROSINE; PROTEIN-TYROSINE-PHOSPHATASE; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, INSULIN; RECOMBINANT FUSION PROTEINS; SHP1 PROTEIN TYROSINE PHOSPHATASE; TRANSFECTION;

EID: 0029995773     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.7.8770882     Document Type: Article

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