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Volumn 12, Issue 3 SUPPL. B, 1998, Pages

Debate resolved: There are differential effects of serotonin selective reuptake inhibitors on cytochrome P450 enzymes

Author keywords

Citalopram; Cytochrome P450 enzymes; Fluoxetine; Fluvoxamine; Paroxetine; Serotonin selective reuptake inhibitors; Sertraline

Indexed keywords

CITALOPRAM; CYTOCHROME P450; DEXTROMETHORPHAN; FLUOXETINE; FLUVOXAMINE; NORTRIPTYLINE; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

EID: 0031733037     PISSN: 02698811     EISSN: None     Source Type: Journal    
DOI: 10.1177/0269881198012003051     Document Type: Article
Times cited : (34)

References (59)
  • 2
    • 0030791275 scopus 로고    scopus 로고
    • Desipramine pharmacokinetics when coadministered with paroxetine or sertraline in extensive metabolizers
    • Alderman J, Preskorn S, Greenblatt D, et al. (1997) Desipramine pharmacokinetics when coadministered with paroxetine or sertraline in extensive metabolizers. J Clin Psychopharmacol 17(4): 284-291.
    • (1997) J Clin Psychopharmacol , vol.17 , Issue.4 , pp. 284-291
    • Alderman, J.1    Preskorn, S.2    Greenblatt, D.3
  • 3
    • 7844220016 scopus 로고    scopus 로고
    • Relationship of venlafaxine, fluoxetine, sertraline, and paroxetine plasma concentration with CYP2D6 inhibition
    • Paper presentated Boca Raton
    • Alfaro C, Ereshefsky L, Lam YWF (1997) Relationship of venlafaxine, fluoxetine, sertraline, and paroxetine plasma concentration with CYP2D6 inhibition. Paper presentated at the 37th Annual Meeting of NCDEU, Boca Raton.
    • (1997) 37th Annual Meeting of NCDEU
    • Alfaro, C.1    Ereshefsky, L.2    Lam, Y.W.F.3
  • 4
    • 79958145717 scopus 로고    scopus 로고
    • Venlafaxine's low drug interaction potential based on cytochrome P450: In vivo evidence confirming in vitro data of low CYP2D6 and no CYP3A4 inhibition
    • Paper presented San Antonio
    • Amchin J, Albano D, Troy S, et al. (1996) Venlafaxine's low drug interaction potential based on cytochrome P450: in vivo evidence confirming in vitro data of low CYP2D6 and no CYP3A4 inhibition. Paper presented at the Annual Meeting of Association of Medicine and Psychiatry, San Antonio.
    • (1996) Annual Meeting of Association of Medicine and Psychiatry
    • Amchin, J.1    Albano, D.2    Troy, S.3
  • 5
    • 0027179196 scopus 로고
    • Pharmacodynamic and pharmacokinetic interactions of selective serotonin re-uptake inhibiting antidepressants (SSRIs) with, other psychotropic drugs
    • Baumann P, Bertschy G (1993) Pharmacodynamic and pharmacokinetic interactions of selective serotonin re-uptake inhibiting antidepressants (SSRIs) with, other psychotropic drugs. Nord J Psychiatry 47 (Suppl. 30): 13-19.
    • (1993) Nord J Psychiatry , vol.47 , Issue.30 SUPPL. , pp. 13-19
    • Baumann, P.1    Bertschy, G.2
  • 7
    • 0031417358 scopus 로고    scopus 로고
    • Assessment of the potential for a pharmacokinetic interaction between fluoxetine and terfenadine
    • Bergstrom R, Goldberg M, Cerimele B, Hatcher B (1997) Assessment of the potential for a pharmacokinetic interaction between fluoxetine and terfenadine. Clin Pharmacol Ther 62: 643-651.
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 643-651
    • Bergstrom, R.1    Goldberg, M.2    Cerimele, B.3    Hatcher, B.4
  • 8
    • 0026552617 scopus 로고
    • Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction
    • Bergstrom RF, Peyton A L, Lemberger L (1992) Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction. Clin Pharmacol Ther 51: 239-248.
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 239-248
    • Bergstrom, R.F.1    Peyton, A.L.2    Lemberger, L.3
  • 9
    • 0029928537 scopus 로고    scopus 로고
    • Are pharmacokinetic drug interactions with the SSRIs an issue?
    • Brosen K (1996) Are pharmacokinetic drug interactions with the SSRIs an issue? Int Clin Psychopharmacol 11: 23-27.
    • (1996) Int Clin Psychopharmacol , vol.11 , pp. 23-27
    • Brosen, K.1
  • 10
    • 0027167470 scopus 로고
    • Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine
    • Brosen K, Hansen JG, Neilsen KK, Sindrup SH, Gram LF (1993) Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine. Eur J Clin Pharmacol 44: 349-355.
    • (1993) Eur J Clin Pharmacol , vol.44 , pp. 349-355
    • Brosen, K.1    Hansen, J.G.2    Neilsen, K.K.3    Sindrup, S.H.4    Gram, L.F.5
  • 11
    • 0029953653 scopus 로고    scopus 로고
    • Serum levels of clozapine and norclozapine in patients treated with selective serotonin reuptake inhibitors
    • Centorrino F, Baidessarini R, Frankenburg F, Kando J, Volpicelli S, Flood J (1996) Serum levels of clozapine and norclozapine in patients treated with selective serotonin reuptake inhibitors. Am J Psychiatry 153: 820-822.
    • (1996) Am J Psychiatry , vol.153 , pp. 820-822
    • Centorrino, F.1    Baidessarini, R.2    Frankenburg, F.3    Kando, J.4    Volpicelli, S.5    Flood, J.6
  • 12
    • 0026787192 scopus 로고
    • The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes
    • Crewe HK, Lennard MS, Tucker GT, Woods FR, Haddock RE (1992) The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes. Br J Clin Pharmacol 34: 262-265.
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 262-265
    • Crewe, H.K.1    Lennard, M.S.2    Tucker, G.T.3    Woods, F.R.4    Haddock, R.E.5
  • 13
    • 0031907041 scopus 로고    scopus 로고
    • Cytochrome P450: New nomenclature and clinical implications
    • Cupp MJ, Tracy TS (1998) Cytochrome P450: new nomenclature and clinical implications [abstract]. Am Fam Physician 57: 107-116.
    • (1998) Am Fam Physician , vol.57 , pp. 107-116
    • Cupp, M.J.1    Tracy, T.S.2
  • 14
    • 0028307888 scopus 로고
    • Disposition of clozapine in man: Lack of association with debrisoquine and S-mephenytoin hydroxylation polymorphisms
    • Dahl M, Llerena A, Bondesson U, Lindstrom L, Bertilsson L (1994) Disposition of clozapine in man: lack of association with debrisoquine and S-mephenytoin hydroxylation polymorphisms. Br J Clin Pharmacol 37: 71-74.
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 71-74
    • Dahl, M.1    Llerena, A.2    Bondesson, U.3    Lindstrom, L.4    Bertilsson, L.5
  • 16
    • 7844220374 scopus 로고    scopus 로고
    • Dr DeVane replies
    • DeVane C L (1996) Dr DeVane replies. J Clin Psychiatry 57: 225-227.
    • (1996) J Clin Psychiatry , vol.57 , pp. 225-227
    • DeVane, C.L.1
  • 17
    • 0029951845 scopus 로고    scopus 로고
    • Drug-drug interactions involving antidepressants: Focus on venlafaxine
    • Ereshefsky L (1996) Drug-drug interactions involving antidepressants: focus on venlafaxine. J Clin Psychopharmacol 16: 37-50.
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 37-50
    • Ereshefsky, L.1
  • 18
    • 7844238409 scopus 로고    scopus 로고
    • Relationship of plasma concentrations of fluoxetine and vealafaxine with effects on CYP2D6 in vivo
    • Poster presentation May 28-31, 1996; Boca Raton, Florida
    • Ereshefsky L, Amchin J, Zarycranski W, Heath G (1996) Relationship of plasma concentrations of fluoxetine and vealafaxine with effects on CYP2D6 in vivo. Poster presentation at the 36th Annual Meeting of New Clinical Drug Evaluation Unit, May 28-31, 1996; Boca Raton, Florida.
    • (1996) 36th Annual Meeting of New Clinical Drug Evaluation Unit
    • Ereshefsky, L.1    Amchin, J.2    Zarycranski, W.3    Heath, G.4
  • 19
    • 0029947311 scopus 로고    scopus 로고
    • Drug interactions, cardiac toxicity, and terfenadine: From bench to clinic?
    • Flockhart D (1996) Drug interactions, cardiac toxicity, and terfenadine: from bench to clinic? J Clin Psychopharmacol 16: 101-103.
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 101-103
    • Flockhart, D.1
  • 20
    • 0027475331 scopus 로고
    • Citalopram: Interaction studies with levomepromazine, imipramine, and lithium
    • Gram LF, Hansen MGJ, Sindrup SH, et al. (1993) Citalopram: interaction studies with levomepromazine, imipramine, and lithium. Ther Drug Monit 15: 18-24.
    • (1993) Ther Drug Monit , vol.15 , pp. 18-24
    • Gram, L.F.1    Hansen, M.G.J.2    Sindrup, S.H.3
  • 21
    • 0030016458 scopus 로고    scopus 로고
    • Cytochrome P450 enzymes: Interpretation of their interactions with selective serotonin reuptake inhibitors. Part I and Part II
    • Harvey A, Preskorn S (1996) Cytochrome P450 enzymes: interpretation of their interactions with selective serotonin reuptake inhibitors. Part I and Part II. J Clin Psychopharmacol 16: 273-285 and 345-355.
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 273-285
    • Harvey, A.1    Preskorn, S.2
  • 23
    • 0029738965 scopus 로고    scopus 로고
    • Dose-dependent inhibition of CYP1A2, CYP2C19, and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine
    • Jeppesen U, Gram L F, Vistisen K, Loft S, Poulsen HE, Brosen K (1996) Dose-dependent inhibition of CYP1A2, CYP2C19, and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine. Eur J Clin Pharmacol 51: 73-78.
    • (1996) Eur J Clin Pharmacol , vol.51 , pp. 73-78
    • Jeppesen, U.1    Gram, L.F.2    Vistisen, K.3    Loft, S.4    Poulsen, H.E.5    Brosen, K.6
  • 24
    • 0028318482 scopus 로고
    • Fluvoxamine inhibition and carbamazepine induction of the metabolism of clozapine: Evidence from a therapeutic drug monitoring service
    • Jerling M, Lindstrom L, Bondesson U, Bertilsson L (1994) Fluvoxamine inhibition and carbamazepine induction of the metabolism of clozapine: evidence from a therapeutic drug monitoring service. Ther Drug Monit 16: 368-374.
    • (1994) Ther Drug Monit , vol.16 , pp. 368-374
    • Jerling, M.1    Lindstrom, L.2    Bondesson, U.3    Bertilsson, L.4
  • 25
    • 0028211190 scopus 로고
    • Possible interaction of sertraline with carbamazepine
    • Joblin M, Ghose K (1994) Possible interaction of sertraline with carbamazepine. N Z Med J 107: 43.
    • (1994) N Z Med J , vol.107 , pp. 43
    • Joblin, M.1    Ghose, K.2
  • 26
    • 0000223179 scopus 로고
    • Drug interaction between sertraline and desipramine or imipramine
    • Kurtz D, Bergstrom R, Goldberg M, Cerimale B (1994) Drug interaction between sertraline and desipramine or imipramine [abstract]. J Clin Pharmacol 34: 10-30.
    • (1994) J Clin Pharmacol , vol.34 , pp. 10-30
    • Kurtz, D.1    Bergstrom, R.2    Goldberg, M.3    Cerimale, B.4
  • 27
    • 0030770609 scopus 로고    scopus 로고
    • The effect of sertraline on the pharmacokinetics of desipramine and imipramine
    • Kurtz D, Bergstrom R, Goldberg M, Cerimele B (1997) The effect of sertraline on the pharmacokinetics of desipramine and imipramine. Clin Phamacol Therap 62: 145-156.
    • (1997) Clin Phamacol Therap , vol.62 , pp. 145-156
    • Kurtz, D.1    Bergstrom, R.2    Goldberg, M.3    Cerimele, B.4
  • 29
    • 0030770870 scopus 로고    scopus 로고
    • Effects of trazodone and fluoxetine in the treatment of major depression: Therapeutic pharmacokinetic and pharmacodynamic interactions through formation of metachlorophenylpiperazine
    • Maes M, Westenberg H, Vandoolaeghe E, Demedts P, Wauters A, Neels H, Meltzer H (1997) Effects of trazodone and fluoxetine in the treatment of major depression: therapeutic pharmacokinetic and pharmacodynamic interactions through formation of metachlorophenylpiperazine. J Clin Psychopharmacol 17: 358-364.
    • (1997) J Clin Psychopharmacol , vol.17 , pp. 358-364
    • Maes, M.1    Westenberg, H.2    Vandoolaeghe, E.3    Demedts, P.4    Wauters, A.5    Neels, H.6    Meltzer, H.7
  • 30
  • 31
    • 0029976064 scopus 로고    scopus 로고
    • Newer antidepressants and the cytochrome P450 system
    • Nemeroff C, DeVane C, Pollock B (1996) Newer antidepressants and the cytochrome P450 system. Am J Psychiatry 153: 311-320.
    • (1996) Am J Psychiatry , vol.153 , pp. 311-320
    • Nemeroff, C.1    DeVane, C.2    Pollock, B.3
  • 32
    • 0009699990 scopus 로고
    • Comparative inhibition of the polymorphic enzyme CYP2D6 by venlafaxine (VF) and other 5HT uptake inhibitors
    • Otton SV, Ball SE, Cheung SW, Inaba T, Sellers EM (1994) Comparative inhibition of the polymorphic enzyme CYP2D6 by venlafaxine (VF) and other 5HT uptake inhibitors [abstract]. Clin Pharmacol Ther 55: 141.
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 141
    • Otton, S.V.1    Ball, S.E.2    Cheung, S.W.3    Inaba, T.4    Sellers, E.M.5
  • 36
    • 0027923337 scopus 로고
    • Recent pharmacologic advances in antidepressant therapy for the elderly
    • Preskorn S (1993) Recent pharmacologic advances in antidepressant therapy for the elderly. Am J Med 94 (Suppl. 5A): 2S-12S.
    • (1993) Am J Med , vol.94 , Issue.SUPPL. 5A
    • Preskorn, S.1
  • 37
    • 0029126505 scopus 로고
    • Comparison of the tolerability of bupropion, fluoxetine, imipramine, nefazodone, paroxetine, sertraline, and venlafaxine
    • Preskorn S (1995) Comparison of the tolerability of bupropion, fluoxetine, imipramine, nefazodone, paroxetine, sertraline, and venlafaxine. J Clin Psychiatry 56: 12-21.
    • (1995) J Clin Psychiatry , vol.56 , pp. 12-21
    • Preskorn, S.1
  • 39
    • 0031025875 scopus 로고    scopus 로고
    • The clinical relevant pharmacology of serotonin selective reuptake inhibitors
    • Preskorn S (1997b) The clinical relevant pharmacology of serotonin selective reuptake inhibitors. Clin Pharmacokinet 32: 1-21.
    • (1997) Clin Pharmacokinet , vol.32 , pp. 1-21
    • Preskorn, S.1
  • 42
    • 0031405692 scopus 로고    scopus 로고
    • Sertraline does not inhibit cytochrome (CYP) 3A-mediated drug metabolism in vivo
    • Preskorn S, Alderman J, Greenblatt D, Horst W D (1997) Sertraline does not inhibit cytochrome (CYP) 3A-mediated drug metabolism in vivo. Psychopharmacol Bull 33: 659-665.
    • (1997) Psychopharmacol Bull , vol.33 , pp. 659-665
    • Preskorn, S.1    Alderman, J.2    Greenblatt, D.3    Horst, W.D.4
  • 43
    • 0025219954 scopus 로고
    • Serious adverse effects of combining fluoxetine and tricyclic antidepressants
    • Preskorn S, Beber JH, Faul JC, Hirschfeld RMA (1990) Serious adverse effects of combining fluoxetine and tricyclic antidepressants. Am J Psychiatry 147: 532.
    • (1990) Am J Psychiatry , vol.147 , pp. 532
    • Preskorn, S.1    Beber, J.H.2    Faul, J.C.3    Hirschfeld, R.M.A.4
  • 46
    • 0029051020 scopus 로고
    • Sertraline 50 mg daily: The optimal dose in the treatment of depression
    • Preskorn S, Lane R (1995) Sertraline 50 mg daily: the optimal dose in the treatment of depression. Int J Clin Pharmacol 10: 129-141.
    • (1995) Int J Clin Pharmacol , vol.10 , pp. 129-141
    • Preskorn, S.1    Lane, R.2
  • 48
    • 0030867948 scopus 로고    scopus 로고
    • Pharmacokinetic drug interactions of new-age antidepressants: A review for the practitioner on effects on the metabolism of other drugs
    • Richelson E (1997) Pharmacokinetic drug interactions of new-age antidepressants: a review for the practitioner on effects on the metabolism of other drugs. Mayo Clin Proc 72(9): 835-847.
    • (1997) Mayo Clin Proc , vol.72 , Issue.9 , pp. 835-847
    • Richelson, E.1
  • 50
    • 0003155654 scopus 로고    scopus 로고
    • Antidepressants
    • Levy RH, Thummer K, Troger B, Hansten P, Eichelbaum M, eds. Lippincott-Raven Publishers, Philadelphia (in press)
    • Shad MU, Preskorn S (1999) Antidepressants. In Levy RH, Thummer K, Troger B, Hansten P, Eichelbaum M, eds. Metabolic drug interactions. Lippincott-Raven Publishers, Philadelphia (in press).
    • (1999) Metabolic Drug Interactions
    • Shad, M.U.1    Preskorn, S.2
  • 52
    • 0026795695 scopus 로고
    • Inhibitors of imipramine metabolism by human liver microsomes
    • Skjelbo E, Brosen K (1992) Inhibitors of imipramine metabolism by human liver microsomes. Br J Clin Pharmacol 34: 256-261.
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 256-261
    • Skjelbo, E.1    Brosen, K.2
  • 54
    • 0027254118 scopus 로고
    • Effect of fluvoxamine on the pharmacokinetics of imipramine and desipramine in healthy subjects
    • Spina E, Pollicino AM, Avenoso A, Campo G M, Perucca E, Caputi AP (1993) Effect of fluvoxamine on the pharmacokinetics of imipramine and desipramine in healthy subjects. Ther Drug Monit 15: 243-246.
    • (1993) Ther Drug Monit , vol.15 , pp. 243-246
    • Spina, E.1    Pollicino, A.M.2    Avenoso, A.3    Campo, G.M.4    Perucca, E.5    Caputi, A.P.6
  • 56
    • 0028898816 scopus 로고
    • Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: Comparison with other selective serotonin reuptake inhibitor antidepressants
    • von Moltke LL, Greenblatt DJ, Court MH, Duan S X, Harmatz JS, Shader RI (1995) Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants. J Clin Psychopharmacol 15: 125-131.
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 125-131
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Court, M.H.3    Duan, S.X.4    Harmatz, J.S.5    Shader, R.I.6
  • 57
    • 0030009690 scopus 로고    scopus 로고
    • Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: Relation to pharmacokinetic interactions in vivo
    • von Moltke LL, Greenblatt DJ, Duan SX, Harmatz JS, Wright C E, Shader RI (1996) Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: relation to pharmacokinetic interactions in vivo. J Clin Psychopharmacol 16: 104-112.
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 104-112
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Duan, S.X.3    Harmatz, J.S.4    Wright, C.E.5    Shader, R.I.6
  • 58
    • 0031033615 scopus 로고    scopus 로고
    • A case of neuroleptic malignant syndrome and serotonin disturbance
    • Young C (1997) A case of neuroleptic malignant syndrome and serotonin disturbance [letter to the editor]. J Clin Psychopharmacol 17: 65-66.
    • (1997) J Clin Psychopharmacol , vol.17 , pp. 65-66
    • Young, C.1
  • 59
    • 0000375514 scopus 로고
    • Sertraline, like other SSRIs, is a significant inhibitor of desipramine metabolism in vivo
    • Zussman B, Davie C, Fowles S, et al. (1995) Sertraline, like other SSRIs, is a significant inhibitor of desipramine metabolism in vivo. BrJ Clin Pharmacol 39: 550-551.
    • (1995) BrJ Clin Pharmacol , vol.39 , pp. 550-551
    • Zussman, B.1    Davie, C.2    Fowles, S.3


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