Activation of the cloned human NK3 receptor in Chinese Hamster Ovary cells characterized by the cellular acidification response using the Cytosensor microphysiometer

British Journal of Pharmacology

Volumn 125, Issue 4, 1998, Pages 761-766

  Jordan, R E ^a   Smart, D ^a   Grimson, P ^a   Suman Chauhan, N ^a   McKnight, A T ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Cytosensor; Microphysiometry; Neurokinin 3 receptor pharmacology; NK3 antagonists; PD168073; Senktide; Signal transduction; Tachykinin

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; [2 (2,3 DIFLUOROPHENYL) 1 METHYL 1 [(7 UREIDOHEPTYL)CARBAMOYL]ETHYL]CARBAMIC ACID 2 METHYL 1 PHENYLPROPYL ESTER; AMILORIDE; ANTIPORTER; CALCIUM ION; NEUROKININ 3 RECEPTOR; OSANETANT; PD 156319 121; PD 168001; PD 168073; PHOSPHOLIPASE C; PROTEIN KINASE C; RADIOLIGAND; SENKTIDE; STAUROSPORINE; SUBSTANCE P; THAPSIGARGIN; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE;

ANIMALS; BIOCHEMISTRY; CELLS, CULTURED; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; EVALUATION STUDIES; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; PEPTIDE FRAGMENTS; RADIOLIGAND ASSAY; RECEPTORS, CHOLECYSTOKININ; RECEPTORS, NEUROKININ-3; SIGNAL TRANSDUCTION; SUBSTANCE P; THAPSIGARGIN;

EID: 0031728128     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702156     Document Type: Article

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