The effect of high dose endotoxin on CYP3A2 expression in the rat

Pharmaceutical Research

Volumn 15, Issue 10, 1998, Pages 1603-1608

  Roe, Amy L ^a,c   Warren, Graham ^a   Hou, Guoqiang ^b   Howard, Georgette ^b   Shedlofsky, Steven I ^a   Blouin, Robert A ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b University of Kentucky   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Activator protein 1 (AP I); Cytochrome P450 3A2 (CYP3A2); Lipopolysaccharide (LPS); Nuclear factor kappa B (NF B); Nuclear factor interleukin 6 (NF IL6)

Indexed keywords

ACUTE PHASE PROTEIN; CYTOCHROME C3; CYTOCHROME C3 A2; ENDOTOXIN; INTERLEUKIN 1; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE PHASE RESPONSE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPUTER ANALYSIS; CONTROLLED STUDY; DNA BINDING; DNA FLANKING REGION; DRUG MEGADOSE; ENDOTOXEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ACUTE-PHASE REACTION; ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; DNA-BINDING PROTEINS; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; LIPOPOLYSACCHARIDES; MALE; NF-KAPPA B; NUCLEAR PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STEROID HYDROXYLASES; TRANSCRIPTION FACTOR AP-1;

EID: 0031715333     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011915402914     Document Type: Article

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