Effects of IL-1O and IL-4 on LPS-induced transcription factors (AP-1, NF-IL6 and NF-κB) which are involved in IL-6 regulation

Leukemia

Volumn 10, Issue 8, 1996, Pages 1308-1316

  Dokter, W H A ^a   Koopmans, S B ^a   Vellenga, E ^a,b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

AML; IL 4; IL10; Transcription factors

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; NUCLEAR FACTOR I; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; CCAAT ENHANCER BINDING PROTEIN; DNA BINDING PROTEIN; NUCLEAR PROTEIN; OLIGODEOXYRIBONUCLEOTIDE; ONCOPROTEIN; RECOMBINANT PROTEIN; RELB PROTEIN, HUMAN; TRANSCRIPTION FACTOR RELB;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MONOCYTE; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; BINDING SITE; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROMOTER REGION;

BASE SEQUENCE; BINDING SITES; BLOTTING, NORTHERN; CCAAT-ENHANCER-BINDING PROTEINS; CELLS, CULTURED; DNA-BINDING PROTEINS; HUMANS; INTERLEUKIN-10; INTERLEUKIN-4; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MOLECULAR SEQUENCE DATA; MONOCYTES; NF-KAPPA B; NUCLEAR PROTEINS; OLIGODEOXYRIBONUCLEOTIDES; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR RELB; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0029666141     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989; 170: 2081-2095.
2. Fernandez-Botran R, Sanders VM, Mosmann TR, Vitetta E. Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells. J Exp Med 1988; 168: 543-549.
3. Rennick D, Berg D, Holland G. Interleukin-10: an overview. Prog Growth Factor Res 1992; 4: 207-227.
4. de Waal Malefyt R, Abrams J, Bennett B, Figdor CC, de Vries JE. Interleukin-10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991; 174: 1209-1220.
5. Moore KW, Vieirra P, Fiorentino DF, Trounstine ML, Khan TA, Mosmann TR. Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRF1. Science 1990; 248: 1230-1234.
6. Fiorentino DF, Zlotnik A, Mosmann TR, Howard M, O'Garra A. IL-10 inhibits cytokine production by activated macrophages. J Immunol 1991; 147: 3815-3820.
7. Oswald IP, Wynn TA, Sher A, James SL. Interleukin-10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor-α required as a co-stimulatory factor for interferon-γ-induced activation. Proc Natl Acad Sci USA 1992; 89: 8676-8681.
8. Wang P, Wu P, Siegel MI, Egan RW, Billah MM. IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells. J Immunol 1994; 153: 811-816.
9. Paul WE. Interleukin-4: a proteolytic immunoregulatory lymphokine. Blood 1991; 77: 1859-1875.
10. Vellenga E, Dokter WHA, Halie MR. Interleukin-4 and its receptor: modulating effects on immature and mature hematopoietic cells. Leukemia 1993; 7: 1131-1141.
11. Punnonen J, de Waal-Malefyt R, van Vlasselaer P, Gauchat JF, de Vries JE. IL-10 and viral IL-10 prevent IL-4 induced IgE synthesis by inhibiting the accessory cell function of monocytes. J Immunol 1993; 151: 1280-1289.
12. Donnelly RP, Fenton MJ, Kaufman JD, Gerrard TL. IL-1 expression in human monocytes is transcriptionally and posttranscriptionally regulated by IL-4. J Immunol 1991; 146: 3431-3436.
13. Hart PH, Vitti GF, Burgers DR, Whitty GA, Piccoii DS, Hamilton JA. Potential anti-inflammatory effects of IL-4. Suppression of human monocyte tumor necrosis factor, interleukin-1 and prostaglandin E2. Proc Natl Acad Sci USA 1989; 68: 3803-3807.
14. Vellenga E, Dokter W, de Wolf JT, van de Vinne B, Esselink MT, Halie MR. Interleukin-4 prevents the induction of C-CSF mRNA in human adherent monocytes in response to endotoxin and IL-1 stimulation. Br J Haematol 1991; 79: 22-26.
15. te Velde AA, Huybens RJ, Heije K, de Vries JE, Figdor CG. Interleukin-4 (IL-4) inhibits secretion of IL-1β tumor necrosis factor-α, and IL-6 by human monocytes. Blood 1990; 76: 1392-1397.
16. Standiford TJ, Strieter RM, Chensue SW, Westwick J, Kasahara K, Kunkel SL. IL-4 inhibits the expression of IL-8 from stimulated human monocytes. J Immunol 1990; 145: 1435-1439.
17. Dokter WHA, Borger P, Hendriks DW, van der Horst I, Halie MR, Vellenga E. Interleukin-4 (IL-4) receptor expression on human T cells is affected by different intracellular signalling pathways and by IL-4 at transcripfional and posttranscriptional level. Blood 1992; 80: 2721-2727.
18. Brakenhoff JPJ, Croot ER, Pannekoek H, Aarden LA. Molecular cloning and expression of hybridoma growth factor in E. coli. J Immunol 1987; 139: 4116-4121.
19. Dokter WHA, Esselink MT, Halie MR, Vellenga E. Interleukin-4 inhibits the lipopolysaccharide-induced expression of c-jun and c-fos messenger RNA and activator protein-1 binding activity in human monocytes. Blood 1993; 81: 337-341.
20. Fort P, Marty L, Piechachzyk M, el-Sabrouty S, Dani C, Jeanteur P, Blanchard JM. Various rat adult tissues express only one major mRNA species from the CAP-dh multigenic family. Nucleic Acids Res 1985; 13: 1431-1435.
21. Schreiber E, Matthias P, Müller MM, Scaffner W. Rapid detection of octamer binding proteins with 'mini extracts', prepared from a small number of cells. Nucleic Acids Res 1989; 17: 6419-6425.
22. Haegeman C, Content J, Volkaert C, Derynck R, Tavernier J, Fiers W. Structural analysis of the sequence encoding for an indudble 26-kDa protein in human fibroblasts. Eur J Biochcm 1986; 159: 625-632.
23. Dokter WHA, Dijkstra AJ, Koopmans SB, Stulp BK, Keck W, Halie MR, Vellenga E. G(Anh)MTetra, a natural bacterial cell wall breakdown product, induces interleukin-1β and interleukin-6 expression in human monocytes. J Biol Chem 1994; 269: 4201-4206.
24. Chiu R, Boyle WJ, Meek J, Smeal T, Hunter T, Karin M. The Fos protein interacts with c-jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell 1988; 54: 541-552.
25. Curran T, Franza BR Jr, Fos and Jun: The AP-1 connection. Cell 1988; 55: 395-401.
26. Nakabeppu Y, Ryder K, Nathans D. DNA binding activities of three murine jun proteins: stimulation by Fos. Cell 1988; 55: 907-918.
27. Halazonetis TD, Georgopoulos K, Greenberg ME, Leder P. C-jun dimerizes with itself and with c-fos, forming complexes of different DNA binding affinities. Cell 1988; 55: 917-928.
28. Kouzarides T, Ziff E. The role of the leucine zipper in the fos-jun interaction. Nature 1988; 336: 646-650.
29. Sassone-Corsi P, Ransone LJ, Lamph WW, Verma IM. Direct interaction between fos and jun nuclear oncoproteins: role of the leucine zipper' domain. Nature 1988; 336: 692-695.
30. Dokter WHA, Sierdsema SJ, Esselink MT, Halie MR, Vellenga E. Interleukin-4 mediated inhibition of c-fos mRNA expression: role of the lipoxygenase directed pathway. Leukemia 1994; 8: 1181-1185.
31. Akira S, Isshiki H, Sugati T, Tanabe O, Knoshita S, Nishio Y, Nakanjima T, Hirano T, Kishimoto T. A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J 1990; 9: 1897-1906.
32. Bäuerle PA, Baltimore D. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor. Cell 1988; 53: 211-217.
33. Ghosh S, Baltimore D. Activation in vitro of NF-κB by phosphorylation of its inhibitor IκB. Nature 1990; 344: 678-682.
34. Bäuerle PA, Baltimore D. A 65-kD subunit of active NF-κB is required for inhibition of NF-κB by IκB. Genes Dev 1989; 3: 1689-1698.
35. Lieberman TA, Baltimore D. Activation of interleukin-6 gene expression through the NF-κB transcription factor. Mol Cell Biol 1990; 10: 2327-2334.
36. Shimizu H, Kishimoto T. Involvement of a NF-κB-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines. Mol Cell Biol 1990; 10: 561-568.
37. 4 transcriptionally activates interleukin-6 expression involving NF-κ and NF-IL6. fur J Immunol 1992; 22: 2705-2711.
38. Gruss HJ, Brach MA, Herrmann F. Involvement of Nuclear factor-κB in induction of the interleukin-6 gene by leukemia inhibitory factor. Blood 1992; 80: 2563-2570.
39. Geng Y, Gulbins E, Altman A, Lotz M. Monocyte deactivation by interleukin-10 via inhibition of tyrosine kinase activity and the Ras signalling pathway. Proc Natl Acad Sci USA 1994; 91: 8602-8606.
40. Nakajima T, Kinoshita S, Sasagawa T, Sasaki K, Naruto M, Kishimoto T, Akira S. Phosphorylation at threonine-235 by a ras-dependent mitogen activated protein kinase casacade is essential for transcription factor NF-IL6. Proc Natl Acad Sci USA 1993; 90: 2207-2211.
41. Miyami A, Mui ALF, Ogorochi T. Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5. Blood 1993; 82: 1960-1974.
42. Musso T, Johnston JA, Linnekin D, Varesio L, Rowe TK, O'Shea JJ, McVicar DW. Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7. J Exp Med 1995; 181: 1425-1431.
43. Kondo M, Takeshita T, Ishii N, Nakamura Y, Watanbe S, Arai K, Sugamura K. Sharing of the interleukin-2 (IL-2) receptor y chain between receptors for IL-2 and IL-4. Science 1993; 262: 1874-1877.
44. Russell SM, Keegan AD, Harada N, Nakamura Y, Noguchi M, Leland P, Friedmann MC, Miyajuma A, Puri RK, Paul WE. Interleukin-2 receptor y chain: a functional component of the interleukin-4 receptor. Science 1993; 262: 1880-1883.
45. Finbloom DS, Winestock KD. IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1α and STAT3 complexes in human T cells and monocytes. J Immunol 1995; 155: 1079-1090.
46. Donnelly RP, Crofford LJ, Freeman SL, Buras J, Remmers E, Wilder RL, Fenton MJ. Tissue-specific regulation of IL-6 production by IL-4. Differential effects of IL-4 on nuclear factor-κB activity in monocytes and fibroblasts. J Immunol 1993; 151: 5603-5608.
47. Wang P, Wu P, Siegel MI, Egan RW, Billah MM. Interleukin-10 inhibits nuclear factor κB (NF-κB) activation in human monocytes. J Biol Chem 1995; 270: 9558-9563.