Reduction of wrap restraint stress-induced defecation by MKC-242, a novel benzodioxan derivative, via 5-HT(1A)-receptor agonist action in rats

Japanese Journal of Pharmacology

Volumn 77, Issue 3, 1998, Pages 211-217

  Abe, Michikazu ^a   Saito, Ken Ichi ^a  

^a MITSUBISHI CHEMICAL CORPORATION   (Japan)

Author keywords

5 HT(1A) receptor; Defecation; Irritable bowel syndrome; MKC 242; Stress

Indexed keywords

1 (2 PYRIMIDINYL)PIPERAZINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; AMITRIPTYLINE; BENZODIOXAN DERIVATIVE; BUSPIRONE; DIAZEPAM; FLUOXETINE; LOPERAMIDE; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; OSEMOZOTAN; OXOTREMORINE; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; TANDOSPIRONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEFECATION; DRUG ANTAGONISM; IMMOBILIZATION STRESS; IRRITABLE COLON; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TREMOR;

EID: 0031713471     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.77.211     Document Type: Article

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