Linkage analysis of dermatophagoides pteronyssinus-specific IgE responsiveness with polymorphic markers on chromosome 6p21 (HLA-D region) in Caucasian families by the transmission/disequilibrium test

Journal of Allergy and Clinical Immunology

Volumn 102, Issue 3, 1998, Pages 443-448

  Hizawa, Nobuyuki ^a   Collins, Gary ^b   Rafnar, Thorunn ^a,c   Huang, Shau Ku ^a   Duffy, David L ^d,e   Weber, James L ^f   Freidhoff, Linda R ^a   Ehrlich, Eva ^a   Marsh, David G ^a   Beaty, Terri H ^d   Barnes, Kathleen C ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c ICELANDIC CANCER SOCIETY   (Iceland)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^e QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^f MARSHFIELD CLINIC   (United States)

Author keywords

Dermatophagoides pteronyssinus specific IgE responsiveness; HLA D genes; Immunoblotting analysis; Transmission disequilibrium test

Indexed keywords

IMMUNOGLOBULIN E;

ARTICLE; ASTHMA; CHROMOSOME 6P; CHROMOSOME MARKER; DERMATOPHAGOIDES PTERONYSSINUS; ENVIRONMENTAL FACTOR; FEMALE; GENETIC LINKAGE; HLA SYSTEM; HUMAN; HUMAN EXPERIMENT; IMMUNOBLOTTING; MALE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

DERMATOPHAGOIDES PTERONYSSINUS;

EID: 0031710512     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(98)70133-2     Document Type: Article

References (28)

1. Freidhoff LR, Ehrlich-Kautzsky E, Meyers DA, Ansari AA, Bias WB, Marsh DG. Association of HLA-DR3 with human immune response to Lol p I and Lol p II allergens in allergic subjects. Tissue Antigens 1988;31:211-9.
2. Cardaba B, Vilches C, Martin E, de Andres B, del Pozo V, Hernandez D, et al. DR7 and DQ2 are positively associated with immunoglobulin-E response to the main antigen of olive pollen (Ole e I) in allergic patients. Hum Immunol 1993;38:293-9.
3. Fischer GF, Pickl WF, Fae I, Ebner C, Ferreira F, Breiteneder H, et al. Association between IgE response against Bet v I, the major allergen of birch pollen, and HLA-DRB alleles. Hum Immunol 1992;25:59-71.
4. Marsh DG, Meyers DA, Freidhoff LR, Ehrlich-Kautzky E, Roebber M, Norman PS, et al. HLA-Dw2: a genetic marker for human response to short ragweed pollen allergen Ra 5. II. Response after ragweed immunotherapy. J Exp Med 1982;155:1452-63.
5. Yssel H, Johnson KE, Schneider PV, Wideman J, Terr A, Kastelein R, et al. T cell activation-inducing epitopes of the house dust mite allergen Der p I-proliferation and lymphokine production patterns by Der p I-specific CD4+ T cell clones. J Immunol 1992;148:738-45.
6. Joost van Neerven RJ, Wim van t'Hof, Ringrose JH, Jansen HM, Aalberse RC, Wierenga EA, et al. T cell epitopes of house dust mite major allergen Der p II. J Immunol 1993;151:2326-35.
7. Young RP, Dekker JW, Wordsworh BP, Schou C, Pile KD, Matthiesen F, et al. HLA-DR and HLA-DP genotyped and immunoglobulin E responses to common major allergens. Clin Exp Allergy 1994;24:431-9.
8. Holloway JW, Doull I, Begishvili B, Beasley R, Holgate ST, Howell WM. Lack of evidence of a significant association between HLA-DR, DQ and DP genotypes and atopy in families with HDM allergy. Clin Exp Allergy 1996;26:1142-9.
9. The World Health Organization/International Union of Immunological Societies (IUIS) allergen nomenclature subcommittee. 1997
10. Shibasaki M, Isoyama S, Takita H. Influence of age on IgE responsiveness to Dermatophagoides farinae: an immunoblot study. Int Arch Allergy Immunol 1994;103:53-8.
11. Collaborative Study on the Genetics of Asthma. A genome-wide search for asthma susceptibility loci in ethnically diverse population. Nat Genet 1997;15:389-92.
12. Blumenthal MN, Banks-Schlegel S, Bleecker ER, Marsh DG, Ober C. Collaborative studies on the genetics of asthma - National Heart, Lung and Blood Institute. Clin Exp Allergy 1995;25:29-32.
13. Hizawa N, Freidhoff LR, Chiu Y-F, Ehrlich E, Luehr CA, Anderson JL, et al. Genetic regulation of Dermatophagoides pteronyssinus-specific IgE responsiveness: a multipoint linkage analysis in families recruited through 2 asthmatic sibs. J Allergy Clin Immunol 1998;102:435-41.
14. Laemmli UK. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 1970;227:680-5.
15. Barnes KC, Neely JD, Duffy DL, Freidhoff LR, Breazeale DR, Schou C, et al. Linkage of asthma and total serum IgE concentration to markers on chromosome 12q: evidence from Afro-Caribbean and Caucasian populations. Genomics 1996;37:41-50.
16. Spielman RS, McGinnis RE, Ewens WJ. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 1993;52:506-16.
17. Duffy DL. Sib-pair: a program for non-parametric linkage/association analysis. Am J Hum Genet 1997;61:A197.
18. Bland M. An introduction to medical statistics: multiple significance test. 2nd ed. Oxford (UK): Oxford University Press; 1995.
19. Marsh DG, Meyers DA, Bias WB. The epidemiology and genetics of atopic allergy. N Engl J Med 1981;305:1551-9.
20. Murray JS, Madri J, Tite J, Carding SR, Bottomly K. MHC control of CD4+ T cell subset activation. J Exp Med 1989;170:2135-40.
21. Schountz T, Kasselman JP, Martinson FA, Brown L, Murray JS. MHC genotype controls the capacity of ligand density to switch T helper (Th)-1/Th-2 priming in vivo. J Immunol 1996;157:3893-901.
22. Caraballo LR, Hernandez M. HLA haplotype segregation in families with allergic asthma. Tissue Antigens 1990;35:182-6.
23. Moffatt MF, Schou C, Faux JA, Cookson WO. Germline TCR-A restriction of immunoglobulin E responses to allergen. Immunogenetics 1997;46:226-30.
24. Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996;273:1516-7.
25. Bennett ST, Wilson AJ, Esposito L, Bouzekri N, Undlien DE, Cucca F, et al. Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele. Nat Genet 1997;17:350-2.
26. Hirayama K, Matsushita S, Kikuchi I, Iuchi M, Ohta N, Sasazuki T. HLA-DQ is epistatic to HLA-DR in controlling the immune response to schistosomal antigen in humans. Nature 1987;327:426-30.
27. Moffatt MF, Cookson WOCM. Tumour necrosis factor haplotypes and asthma. Hum Mol Genet 1997;6:551-4.
28. Ismail A, Bousaffara R, Kaziz J, Zili J, el Kamel A, Tahar Sfar M, et al. Polymorphism in transporter antigen peptides gene (TAP1) associated with atopy in Tunisians. J Allergy Clin Immunol 1997;99:216-23.