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Volumn 72, Issue 10, 1998, Pages 8166-8173

A fifteen-amino-acid peptide inhibits human papillomavirus E1-E2 interaction and human papillomavirus DNA replication in vitro

Author keywords

[No Author keywords available]

Indexed keywords

SYNTHETIC PEPTIDE; VIRUS DNA; VIRUS PROTEIN;

EID: 0031709416     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.10.8166-8173.1998     Document Type: Article
Times cited : (34)

References (48)
  • 1
    • 0029793364 scopus 로고    scopus 로고
    • Transcriptional and replicational activation functions in the papillomavirus type 1 E2 protein are encoded by different structural determinants
    • Abroi, A., R. Kurg, and M. Ustav. 1996. Transcriptional and replicational activation functions in the papillomavirus type 1 E2 protein are encoded by different structural determinants. J. Virol. 70:6169-6179.
    • (1996) J. Virol. , vol.70 , pp. 6169-6179
    • Abroi, A.1    Kurg, R.2    Ustav, M.3
  • 2
    • 0023178843 scopus 로고
    • Bovine papillomavirus E2 trans-activating gene product binds to specific sites in papillomavirus DNA
    • Androphy, E. J., D. R. Lowy, and J, T. Schiller. 1987. Bovine papillomavirus E2 trans-activating gene product binds to specific sites in papillomavirus DNA. Nature 325:70-73.
    • (1987) Nature , vol.325 , pp. 70-73
    • Androphy, E.J.1    Lowy, D.R.2    Schiller, J.T.3
  • 3
    • 0025964892 scopus 로고
    • The 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro
    • Blitz, I. L., and L. A. Laimins. 1991. The 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro. J. Virol. 65:649-656.
    • (1991) J. Virol. , vol.65 , pp. 649-656
    • Blitz, I.L.1    Laimins, L.A.2
  • 4
    • 0028932075 scopus 로고
    • Bovine papillomavirus E1 protein binds specifically DNA polymerase α but not replication protein A
    • Bonne-Andrea, C., S. Santucci, P. Clertant, and F. Tillier. 1995. Bovine papillomavirus E1 protein binds specifically DNA polymerase α but not replication protein A. J. Virol. 69:2341-2350.
    • (1995) J. Virol. , vol.69 , pp. 2341-2350
    • Bonne-Andrea, C.1    Santucci, S.2    Clertant, P.3    Tillier, F.4
  • 5
    • 0028922126 scopus 로고
    • Bovine papillomavirus E1 protein can, by itself, efficiently drive multiple rounds of DNA synthesis in vitro
    • Bonne-Andrea, C., S. Santucci, and P. Clertant. 1995. Bovine papillomavirus E1 protein can, by itself, efficiently drive multiple rounds of DNA synthesis in vitro. J. Virol. 69:3201-3205.
    • (1995) J. Virol. , vol.69 , pp. 3201-3205
    • Bonne-Andrea, C.1    Santucci, S.2    Clertant, P.3
  • 6
    • 0030198932 scopus 로고    scopus 로고
    • Genetic analysis of the bovine papillomavirus E2 transcriptional activation domain
    • Breiding, D. E., M. J. Grossel, and E. J. Androphy. 1996. Genetic analysis of the bovine papillomavirus E2 transcriptional activation domain. Virology 221:34-43.
    • (1996) Virology , vol.221 , pp. 34-43
    • Breiding, D.E.1    Grossel, M.J.2    Androphy, E.J.3
  • 7
    • 0029656196 scopus 로고    scopus 로고
    • Amino acids critical for the functions of the bovine papillomavirus type 1 transactivator
    • Brokaw, J. L., M. Blanco, and A. A. McBride. 1996. Amino acids critical for the functions of the bovine papillomavirus type 1 transactivator. J. Virol. 70:23-29.
    • (1996) J. Virol. , vol.70 , pp. 23-29
    • Brokaw, J.L.1    Blanco, M.2    McBride, A.A.3
  • 8
    • 0021213168 scopus 로고
    • A common function for polyoma virus large-T and papillomavirus E1 proteins?
    • Clertant, P., and I. Seif. 1984. A common function for polyoma virus large-T and papillomavirus E1 proteins? Nature (London) 311:276-279.
    • (1984) Nature (London) , vol.311 , pp. 276-279
    • Clertant, P.1    Seif, I.2
  • 10
    • 0029903007 scopus 로고    scopus 로고
    • Genetic analysis of the activation domain of bovine papillomavirus protein E2: Its role in transcription and replication
    • Ferguson, M. F., and M. R. Botchan. 1996. Genetic analysis of the activation domain of bovine papillomavirus protein E2: its role in transcription and replication. J. Virol. 70:4193-4199.
    • (1996) J. Virol. , vol.70 , pp. 4193-4199
    • Ferguson, M.F.1    Botchan, M.R.2
  • 11
    • 0028588659 scopus 로고
    • Induction of structural changes in the bovine papillomavirus type 1 origin of replication by the viral E1 and E2 proteins
    • Gillette, T. G., M. Lusky, and J. A. Boroweic. 1994. Induction of structural changes in the bovine papillomavirus type 1 origin of replication by the viral E1 and E2 proteins. Proc. Natl. Acad. Sci. USA 91:8846-8850.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8846-8850
    • Gillette, T.G.1    Lusky, M.2    Boroweic, J.A.3
  • 12
    • 0028145637 scopus 로고
    • E1 protein of human papillomavirus type 1a is sufficient for initiation of viral DNA replication
    • Gopalakarishan, V., and S. A. Khan. 1994. E1 protein of human papillomavirus type 1a is sufficient for initiation of viral DNA replication. Proc. Natl. Acad. Sci. USA 91:9597-9601.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9597-9601
    • Gopalakarishan, V.1    Khan, S.A.2
  • 13
    • 0029840780 scopus 로고    scopus 로고
    • Transcriptional activation function is not required for stimulation of DNA replication by bovine papillomavirus type 1 E2
    • Grossel, M. J., F. Sverdrup, D. E. Breiding, and E. J. Androphy. 1996. Transcriptional activation function is not required for stimulation of DNA replication by bovine papillomavirus type 1 E2. J. Virol. 70:7264-7269.
    • (1996) J. Virol. , vol.70 , pp. 7264-7269
    • Grossel, M.J.1    Sverdrup, F.2    Breiding, D.E.3    Androphy, E.J.4
  • 14
    • 0028089020 scopus 로고
    • DNA binding specificity of the bovine papillomavirus E1 protein is determined by the sequences contained within an 18-base-pair inverted repeat element at the origin of replication
    • Holt, S. E., G. Schuller, and V. G. Wilson. 1993. DNA binding specificity of the bovine papillomavirus E1 protein is determined by the sequences contained within an 18-base-pair inverted repeat element at the origin of replication. J. Virol. 68:1094-1102.
    • (1993) J. Virol. , vol.68 , pp. 1094-1102
    • Holt, S.E.1    Schuller, G.2    Wilson, V.G.3
  • 15
    • 0029132024 scopus 로고
    • Mutational analysis of the 18-base-pair inverted repeat element at the bovine papillomavirus origin of replication: Identification of critical sequences for E1 binding and in vivo replication
    • Holt, S. E., and V. G. Wilson. 1995. Mutational analysis of the 18-base-pair inverted repeat element at the bovine papillomavirus origin of replication: identification of critical sequences for E1 binding and in vivo replication. J. Virol. 69:6525-6532.
    • (1995) J. Virol. , vol.69 , pp. 6525-6532
    • Holt, S.E.1    Wilson, V.G.2
  • 16
    • 0027763449 scopus 로고
    • E1 protein of human papillomavirus is a DNA helicase/ATPase
    • Hughes, F. J., and M. A. Romanos. 1993. E1 protein of human papillomavirus is a DNA helicase/ATPase. Nucleic Acids Res. 21:5817-5823.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 5817-5823
    • Hughes, F.J.1    Romanos, M.A.2
  • 18
    • 0028003643 scopus 로고
    • Cell-free replication of human papillomavirus DNA with homologous viral E1 and E2 proteins and human cell extracts
    • Kuo, S.-R., J.-S. Liu, T. R. Broker, and L. T. Chow. 1994. Cell-free replication of human papillomavirus DNA with homologous viral E1 and E2 proteins and human cell extracts. J. Biol. Chem. 269:24058-24065.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24058-24065
    • Kuo, S.-R.1    Liu, J.-S.2    Broker, T.R.3    Chow, L.T.4
  • 19
    • 0028226007 scopus 로고
    • Acidic transcription factors alleviate nucleosome-mediated repression of DNA replication of bovine papillomavirus type 1
    • Li, R., and M. Botchan. 1994. Acidic transcription factors alleviate nucleosome-mediated repression of DNA replication of bovine papillomavirus type 1. Proc. Natl. Acad. Sci. USA 91:7051-7055.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7051-7055
    • Li, R.1    Botchan, M.2
  • 20
    • 0028805789 scopus 로고
    • The functions of human papillomavirus type 11 E1, E2, and E2C proteins in cell-free DNA replication
    • Liu, J.-S., S.-R. Kuo, T. R. Broker, and L. T. Chow. 1995. The functions of human papillomavirus type 11 E1, E2, and E2C proteins in cell-free DNA replication. J. Biol. Chem. 270:27283-27291.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27283-27291
    • Liu, J.-S.1    Kuo, S.-R.2    Broker, T.R.3    Chow, L.T.4
  • 21
    • 0027179504 scopus 로고
    • Cooperative assembly of the bovine papilloma virus E1 and E2 proteins on the replication origin requires an intact E2 binding site
    • Lusky, M., J. Hurwitz, and Y.-S. Seo. 1993. Cooperative assembly of the bovine papilloma virus E1 and E2 proteins on the replication origin requires an intact E2 binding site. J. Biol. Chem. 268:15795-15803.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15795-15803
    • Lusky, M.1    Hurwitz, J.2    Seo, Y.-S.3
  • 22
    • 0028586001 scopus 로고
    • The bovine papillomavirus E2 protein modulates the assembly of but is not stably maintained in a replication-competent multimeric E1-replication origin complex
    • Lusky, M., J. Hurwitz, and Y.-S. Seo. 1994. The bovine papillomavirus E2 protein modulates the assembly of but is not stably maintained in a replication-competent multimeric E1-replication origin complex. Proc. Natl. Acad. Sci. USA 91:8895-8899.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8895-8899
    • Lusky, M.1    Hurwitz, J.2    Seo, Y.-S.3
  • 23
    • 0030820351 scopus 로고    scopus 로고
    • Bovine papillomavirus type 1 E1 and simian virus 40 large T antigen share regions of sequence similarity required for multiple functions
    • Mansky, K. C., A. Batiza, and P. F. Lambert. 1997. Bovine papillomavirus type 1 E1 and simian virus 40 large T antigen share regions of sequence similarity required for multiple functions. J. Virol. 71:7600-7608.
    • (1997) J. Virol. , vol.71 , pp. 7600-7608
    • Mansky, K.C.1    Batiza, A.2    Lambert, P.F.3
  • 24
    • 0023958594 scopus 로고
    • The carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity
    • McBride, A. A., R. Schlegel, and P. M. Howley. 1988. The carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity. EMBO J. 7:533-539.
    • (1988) EMBO J. , vol.7 , pp. 533-539
    • McBride, A.A.1    Schlegel, R.2    Howley, P.M.3
  • 25
    • 1842367150 scopus 로고
    • E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: Transactivation is mediated by the conserved amino-terminal domain
    • McBride, A. A., C. C. Byrne, and P. M. Howley. 1989. E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain. Proc. Natl. Acad. Sci. USA 86:510-514.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 510-514
    • McBride, A.A.1    Byrne, C.C.2    Howley, P.M.3
  • 26
    • 0028871752 scopus 로고
    • Cellular factors required for papillomavirus DNA replication
    • Melendy, T., J. Sedman, and A. Stenlund. 1995. Cellular factors required for papillomavirus DNA replication. J. Virol. 69:7857-7867.
    • (1995) J. Virol. , vol.69 , pp. 7857-7867
    • Melendy, T.1    Sedman, J.2    Stenlund, A.3
  • 27
    • 0029037088 scopus 로고
    • E1 recognition sequences in the bovine papillomavirus type 1 origin of replication: Interaction between half sites of the inverted repeats
    • Mendoza, R., L. Gandhi, and M. R. Botchan. 1995. E1 recognition sequences in the bovine papillomavirus type 1 origin of replication: interaction between half sites of the inverted repeats. J. Virol. 69:3789-3798.
    • (1995) J. Virol. , vol.69 , pp. 3789-3798
    • Mendoza, R.1    Gandhi, L.2    Botchan, M.R.3
  • 28
    • 0025613266 scopus 로고
    • Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator
    • Mohr, I., J. R. Clark, S. Sun, E. J. Androphy, P. MacPherson, and M. R. Botchan. 1990. Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science 250:1694-1699.
    • (1990) Science , vol.250 , pp. 1694-1699
    • Mohr, I.1    Clark, J.R.2    Sun, S.3    Androphy, E.J.4    MacPherson, P.5    Botchan, M.R.6
  • 29
    • 0028352747 scopus 로고
    • Replication of bovine papillomavirus type 1 origin-containing DNA in crude extracts and with purified proteins
    • Müller, F., Y.-S. Seo, and J. Hurwitz. 1994. Replication of bovine papillomavirus type 1 origin-containing DNA in crude extracts and with purified proteins. J. Biol. Chem. 269:17086-17094.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17086-17094
    • Müller, F.1    Seo, Y.-S.2    Hurwitz, J.3
  • 30
    • 0028133256 scopus 로고
    • The cellular DNA polymerase a-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase
    • Park, P., W. Copeland, L. Yang, T. Wang, M. R. Botchan, and I. J. Mohr. 1994. The cellular DNA polymerase a-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase, Proc. Natl. Acad. Sci. USA 91:8700-8704.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8700-8704
    • Park, P.1    Copeland, W.2    Yang, L.3    Wang, T.4    Botchan, M.R.5    Mohr, I.J.6
  • 31
    • 0030069004 scopus 로고    scopus 로고
    • Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions
    • Sakai, H., T. Yasugi, J. D. Benson, J. J. Dowhanick, and P. M. Howley. 1996. Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions. J. Virol. 70:1602-1611.
    • (1996) J. Virol. , vol.70 , pp. 1602-1611
    • Sakai, H.1    Yasugi, T.2    Benson, J.D.3    Dowhanick, J.J.4    Howley, P.M.5
  • 32
    • 0029617680 scopus 로고
    • Cooperative interaction between the initiator E1 and the transcriptional activator E2 is required for replication of bovine papillomavirus in vivo and in vitro
    • Sedman, J., and A. Stenlund. 1995. Cooperative interaction between the initiator E1 and the transcriptional activator E2 is required for replication of bovine papillomavirus in vivo and in vitro. EMBO J. 14:6218-6228.
    • (1995) EMBO J. , vol.14 , pp. 6218-6228
    • Sedman, J.1    Stenlund, A.2
  • 33
    • 0029815671 scopus 로고    scopus 로고
    • The initiator protein E1 binds to the bovine papillomavirus origin of replication as a trimeric ring-like structure
    • Sedman, J., and A. Stenlund. 1996. The initiator protein E1 binds to the bovine papillomavirus origin of replication as a trimeric ring-like structure. EMBO J. 15:5085-5092.
    • (1996) EMBO J. , vol.15 , pp. 5085-5092
    • Sedman, J.1    Stenlund, A.2
  • 34
    • 0030977244 scopus 로고    scopus 로고
    • Binding of the E1 and E2 proteins to the origin of replication of bovine papillomavirus
    • Sedman, T., J. Sedman, and A. Stenlund. 1997. Binding of the E1 and E2 proteins to the origin of replication of bovine papillomavirus. J. Virol. 71:2887-2896.
    • (1997) J. Virol. , vol.71 , pp. 2887-2896
    • Sedman, T.1    Sedman, J.2    Stenlund, A.3
  • 35
    • 0027400464 scopus 로고
    • Bovine papilloma virus (BPV)-encoded E2 protein enhances binding of E1 protein to the BPV replication origin
    • Seo, Y.-S., F. Müller, M. Lusky, E. Gibbs, H.-Y. Kim, B. Phillips, and J. Hurwitz. 1993. Bovine papilloma virus (BPV)-encoded E2 protein enhances binding of E1 protein to the BPV replication origin. Proc. Natl. Acad. Sci. USA 90:2865-2869.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2865-2869
    • Seo, Y.-S.1    Müller, F.2    Lusky, M.3    Gibbs, E.4    Kim, H.-Y.5    Phillips, B.6    Hurwitz, J.7
  • 36
    • 0027402449 scopus 로고
    • Bovine papillomavirus (BPV)-encoded E1 protein contains multiple activities required for BPV DNA replication
    • Seo, Y.-S., F. Müller, M. Lusky, and J. Hurwitz. 1993. Bovine papillomavirus (BPV)-encoded E1 protein contains multiple activities required for BPV DNA replication. Proc. Natl. Acad. Sci. USA 90:702-706.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 702-706
    • Seo, Y.-S.1    Müller, F.2    Lusky, M.3    Hurwitz, J.4
  • 37
    • 0025048755 scopus 로고
    • Identification of a 68-kilodalton nuclear ATP-binding phosphoprotein encoded by bovine papillomavirus type 1
    • Sun, S., L. Thorner, M. Lentz, P. MacPherson, and M. Botchan. 1990. Identification of a 68-kilodalton nuclear ATP-binding phosphoprotein encoded by bovine papillomavirus type 1. J. Virol. 64:5093-5105.
    • (1990) J. Virol. , vol.64 , pp. 5093-5105
    • Sun, S.1    Thorner, L.2    Lentz, M.3    MacPherson, P.4    Botchan, M.5
  • 38
    • 0027976786 scopus 로고
    • Replication of human papillomavirus (HPV) DNAs supported by the HPV type 18 E1 and E2 proteins
    • Sverdrup, F., and S. A. Khan. 1994. Replication of human papillomavirus (HPV) DNAs supported by the HPV type 18 E1 and E2 proteins. J. Virol. 68:505-509.
    • (1994) J. Virol. , vol.68 , pp. 505-509
    • Sverdrup, F.1    Khan, S.A.2
  • 39
    • 0027313580 scopus 로고
    • DNA-binding domain of bovine papillomavirus type 1 E1 helicase: Structural and functional aspects
    • Thorner, L. K., D. A. Lim, and M. R. Botchan. 1993. DNA-binding domain of bovine papillomavirus type 1 E1 helicase: structural and functional aspects. J. Virol. 67:6000-6014.
    • (1993) J. Virol. , vol.67 , pp. 6000-6014
    • Thorner, L.K.1    Lim, D.A.2    Botchan, M.R.3
  • 40
    • 0026034125 scopus 로고
    • Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames
    • Ustav, M., and A. Stenlund. 1991. Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames. EMBO J. 10:449-457.
    • (1991) EMBO J. , vol.10 , pp. 449-457
    • Ustav, M.1    Stenlund, A.2
  • 41
    • 0026094709 scopus 로고
    • A bovine papillomavirus E1-related protein binds specifically to bovine papillomavirus DNA
    • Wilson, V. G., and J. Ludes-Meyers. 1991. A bovine papillomavirus E1-related protein binds specifically to bovine papillomavirus DNA. J. Virol. 65:5314-5322.
    • (1991) J. Virol. , vol.65 , pp. 5314-5322
    • Wilson, V.G.1    Ludes-Meyers, J.2
  • 42
    • 0026758384 scopus 로고
    • Separation of the transcriptional activation and replication functions of the bovine papillomavirus-1 E2 protein
    • Winokur, P. L., and A. A. McBride. 1992. Separation of the transcriptional activation and replication functions of the bovine papillomavirus-1 E2 protein. EMBO J. 11:4111-4118.
    • (1992) EMBO J. , vol.11 , pp. 4111-4118
    • Winokur, P.L.1    McBride, A.A.2
  • 43
    • 0025989907 scopus 로고
    • Activation of BPV-1 replication in vitro by the transcription factor E2
    • Yang, L., R. Li, I. J. Mohr, R. Clark, and M. R. Botchan. 1991. Activation of BPV-1 replication in vitro by the transcription factor E2. Nature (London) 353:628-632.
    • (1991) Nature (London) , vol.353 , pp. 628-632
    • Yang, L.1    Li, R.2    Mohr, I.J.3    Clark, R.4    Botchan, M.R.5
  • 45
    • 0031016642 scopus 로고    scopus 로고
    • Mapping and characterization of the interaction domains of the human papillomavirus type 16 E1 and E2 proteins
    • Yasugi, T., J. D. Benson, H. Sakai, M. Vidal, and P. M. Howley. 1997. Mapping and characterization of the interaction domains of the human papillomavirus type 16 E1 and E2 proteins. J. Virol. 71:891-899.
    • (1997) J. Virol. , vol.71 , pp. 891-899
    • Yasugi, T.1    Benson, J.D.2    Sakai, H.3    Vidal, M.4    Howley, P.M.5
  • 46
    • 0030745291 scopus 로고    scopus 로고
    • Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization. E2 interaction, and interaction with cellular proteins
    • Yasugi, T., M. Vidal, H. Sakai, P. M. Howley, and J. D. Benson. 1997. Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization. E2 interaction, and interaction with cellular proteins. J. Virol. 71:5942-5951.
    • (1997) J. Virol. , vol.71 , pp. 5942-5951
    • Yasugi, T.1    Vidal, M.2    Sakai, H.3    Howley, P.M.4    Benson, J.D.5
  • 47
    • 0031949270 scopus 로고    scopus 로고
    • The carboxyl-terminal region of the human papillomavirus type 16 E1 protein determines E2 protein specificity during DNA replication
    • Zou, N., J.-S. Liu, S.-R. Kuo, T. R. Broker, and L. T. Chow. 1998. The carboxyl-terminal region of the human papillomavirus type 16 E1 protein determines E2 protein specificity during DNA replication. J. Virol. 72:3436-3441.
    • (1998) J. Virol. , vol.72 , pp. 3436-3441
    • Zou, N.1    Liu, J.-S.2    Kuo, S.-R.3    Broker, T.R.4    Chow, L.T.5
  • 48
    • 0026322149 scopus 로고
    • Viruses in human cancers
    • zur Hausen, H. 1991. Viruses in human cancers. Science 254:1167-1173.
    • (1991) Science , vol.254 , pp. 1167-1173
    • Zur Hausen, H.1


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