Characterization of the helicase and ATPase activity of human papillomavirus type 6b E1 protein

Journal of General Virology

Volumn 77, Issue 8, 1996, Pages 1805-1809

  Jenkins, Owen ^a   Earnshaw, David ^b   Sarginson, Gillian ^a   Del Vecchio, Alfred ^c   Tsai, Jane ^c   Kallender, Howard ^a   Amegadzie, Bernard ^c   Browne, Michael ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b Dept Molec Virol and Host Def ^*  (United Kingdom)

^c Dept of Gene Expression Sciences ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; HELICASE; VIRUS ENZYME;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; WART VIRUS;

EID: 0029741383     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-77-8-1805     Document Type: Article

References (25)

1. Blitz, I. L. & Laimins, L. A. (1991). The 68-kDa E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro. Journal of Virology 65, 649-656.
2. Bream, G., Ohmstede, C.-A. & Phelps, W. (1993). Characterization of human papillomavirus type 11 E1 and E2 proteins expressed in insect cells. Journal of Virology 67, 2655-2663.
3. Chiang, C.-M., Ustav, M., Stenlund, A., Ho, T., Broker, T. & Chow, L. (1992). Viral E1 and E2 proteins support replication of homologous and heterologous papillomavirus origins. Biochemistry 89, 5799-5803.
4. Chow, L. T. & Broker, T. R. (1994). Papillomavirus DNA replication. Intervirology 37, 150-158.
5. Clark, R., Lane, D. & Tjian, R. (1981). Use of monoclonal antibodies as probes of simian virus 40 T antigen ATPase activity. Journal of Biological Chemistry 254, 11854-11858.
6. Del Vecchio, A., Romanzuk, H., Howley, P. & Baker, C. (1992). Transient replication of human papillomavirus DNAs. Journal of Virology 66, 5949-5958.
7. Earnshaw, D. L. & Jarvest, R. L. (1994). Characterization of the nucleotide and DNA coeffector binding sites of the herpes simplex virus (HSV-1) encoded helicase-primase complex and UL9 origin binding protein. Biochemical and Biophysical Research Communications 199, 1333-1340.
8. Gopalakrishnan, V. & Khan, S. A. (1994). E1 protein of human papillomavirus type 1a is sufficient for initiation of viral DNA replication. Proceedings of the National Academy of Sciences, USA 91, 9597-9601.
9. Hughes, F. & Romanes, M. (1993). E1 protein of human papillomavirus is a DNA helicase/ATPase. Nucleic Acids Research 21, 5817-5823.
10. Kuo, S.-R., Liu, J.-S., Broker, T. & Chow, L. (1994). Cell-free replication of the human papillomavirus DNA with homologous viral E1 and E2 proteins and human cell extracts. Journal of Biological Chemistry 269, 24058-24065.
11. Lu, J. Z.-J., Sun, Y.-N., Rose, R. C., Bonnez, W. & McCanee, D. J. (1993). Two E2 binding site (E2BS) alone or one E2BS plus an A/T-rich region are minimal requirements for replication of the human papillomavirus type 11 origin. Journal of Virology 67, 7131-7139.
12. Lusky, M., Hurwitz, J. & Seo, Y. S. (1993). Co-operative assembly of the bovine papillomavirus E1 and E2 proteins on the replication origin requires an intact E2 binding site. Journal of Biological Chemistry 268, 15795-15803.
13. Lusky, M., Hurwitz, J. & Seo, Y. S. (1994). The bovine papillomavirus E2 protein modulates the assembly of but is not stably maintained in a replication-competent multimeric E1-replication origin complex. Proceedings of the National Academy of Sciences, USA 91, 8895-8899.
14. MacPherson, P., Thorner, L., Parker, L. M. & Botchan, M. (1994). The bovine papillomavirus E1 protein has ATPase activity essential to viral DNA replication and efficient transformation in cells. Virology 204, 403-408.
15. May, K., Planterose, D. N., Browne, M. J. & Perkins, R. M. (1991). Development of a novel marker gene based assay system for detection and evaluation of antiviral agents with activity against papillomaviruses. Antiuiral Agents and Chemotherapy 2, 363-370.
16. Mohr, I. J., Clark, R., Sun, S., Androphy, E. J., MacPherson, P. & Botchan, M. R. (1990). Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science 250, 1694-1699.
17. Santucci, S., Bonne-Andréa, C. & Clertant, P. (1995). Bovine papillomavirus type 1 E1 ATPase activity does not depend on binding to DNA nor to viral E2 protein. Journal of General Virology 76, 1129-1140.
18. Seo, Y.-S., Muller, F., Lusky, M. & Hurwitz, J. (1993a). Bovine papillomavirus (BPV)-encoded E1 protein contains multiple activities required for BPV DNA replication. Proceedings of the National Academy of Sciences, USA 90, 702-706.
19. Seo, Y.-S., Muller, F., Lusky, M., Gibbs, E., Kim, H. Y., Phillips, B. & Hurwitz, J. (1993a). Bovine papillomavirus (BPV)-encoded E2 protein enhances binding of E1 protein to the BPV replication origin. Proceedings of the National Academy of Sciences, USA 90, 2865-2869.
20. Sun, S., Thorner, L., Lentz, M., MacPherson, P. & Botchan, M. (1990). Identification of a 68 kilodalton nuclear ATP-binding phosphoprotein encoded by bovine papillomavirus type 1. Journal of Virology 64, 5093-5105.
21. Ustav, E. & Stenlund, A. (1991). Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames. EMBO Journal 10, 449-457.
22. Ustav, E., Ustav, M., Szymanski, P. & Stenlund, A. (1991). Identification of the origin of replication of bovine papillomavirus and characterization of the viral origin recognition factor E1. EMBO Journal 10, 4321-4329.
23. Wilson, V. G. & Ludes-Meyers, J. (1991). A bovine papillomavirus E1-related protein binds specifically to bovine papillomavirus DNA. Journal of Virology 65, 5314-5322.
24. Yang, L., Li, R., Mohr, I. J., Clark, R. & Botchan, M. (1991). Activation of BPV-1 replication in vitro by the transcription factor E2. Nature 353, 628-632.
25. Yang, L., Mohr, I., Fouts, E., Lim, D. A., Nohaile, M. & Botchan, M. (1993). The E1 protein of bovine papillomavirus type 1 is an ATP-dependent DNA helicase. Proceedings of the National Academy of Sciences, USA 90, 5086-5090.