Follitropin signal transduction: Alternative splicing of the FSH receptor gene produces a dominant negative form of receptor which inhibits hormone action

Biochemical and Biophysical Research Communications

Volumn 226, Issue 3, 1996, Pages 717-722

  Sairam, M R ^a   Jiang, L G ^a   Yarney, T A ^a   Khan, H ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CHOLERA TOXIN; COMPLEMENTARY DNA; CYCLIC AMP; FOLLITROPIN; FOLLITROPIN RECEPTOR; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; HORMONE RESPONSE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; TESTIS CELL;

ANIMALIA; OVIS ARIES;

EID: 0030600396     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1996.1419     Document Type: Article

References (20)

1. 1. Sairam, M. R. (1983) In: Hormonal proteins and Peptides. Vol. 11. Gonadotropins. (Li, C. H., Ed.), pp. 1-79, Academic Press, New York.
2. 2. Russell, L. D., and Griswold, M. D. (Eds.), (1993) The Sertoli cell. Cache River Press, Clearwater, FL.
3. 3. Means, A. R., Dedman, J. R., Tindall, J. S., VanSickle, M., and Welsh, M. J. (1980) Ann. Rev. Physiol. 42, 59-70.
4. 4. Watson, S., and Arkinstall, S. (1994). Eds. The G protein linked receptor facts book. pp. 1-291. Acad. Press, London.
5. 5. Sharp, P. A. (1994) Cell 77, 805-815.
6. 6. Sprengel, R., Braun, T., Nikolics, K., Segaloff, D. L., and Seeburg, P. H. (1990) Mol. Endocrinol. 4, 525-530.
7. 7. Kelton, C. A., Cheng, S. V. Y., Nugent, N. P., Schweickhardt, R. L., Rosenthal, J. L., Overton, S. A., Wands, G. D., Kuzeja, J. B., Luchette, C. A., and Chappel, S. C. (1992) Mol. Cell Endocrinol. 89, 141-151.
8. 8. Yarney, T. A., Sairam, M. R., Khan, H., Ravindranath, N., Payne, S., and Seidah, N. G. (1993). Mol. Cell. Endocrinol. 93, 219-226.
9. 9. Gromoll, J., Dankbar, B., Sharma, R. S., and Nieschlag, E. (1993) Biochem. Biophys, Res. Commun. 196, 1066-1072.
10. 10. Houde, A., Lambert, A., Saumande, J., Silversides, D. W., and Lussier, J. G. (1994) Mol. Rep. Dev. 39, 127-135.
11. 11. Robert, P., Amsellem, S., Christophe, S., Benifla, J. L., Bellet, D., Koman, A., and Bidart, J. M. (1994) Biochem. Biophys. Res. Commun. 201, 201-207.
12. 12. Khan, H. A., Yarney, T. A., and Sairam, M. R. (1993) Biochem. Biophys. Res. Commun. 190, 888-894.
13. 13. Yarney, T. A., Jiang, L. G., Khan, H., Macdonald, E., Laird, D. W., and Sairam, M. R. (1996), Submitted for publication.
14. 14. Kozak, M. (1994) Biochimie 26, 815-821.
15. 15. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular cloning, Vols. 1 and 2, Cold Spring Harbor Laboratory press, New York.
16. 16. Heckert, L. L., Daley, I. J., and Griswold, M. D. (1992) Mol. Endocrinol. 6, 70-80.
17. 17. Wong, Y. H. (1994) Methods in Enzymol 238, 81-94.
18. 18. Conklin, B. R., and Bourne, H. R. (1993) Cell 73, 631-641.
19. 19. Raymond, J. R. (1995) Am. J. Physiol. 269, F141-F158.
20. 20. Sairam, M. R., Jiang, L. G., Khan H., and Yarney, T. A. (1996). 10th Int. Cong. Endocrinol., San Francisco. Abst. # P3-297.