Effects of ethanol on recombinant glycine receptors expressed in mammalian cell lines

Alcoholism: Clinical and Experimental Research

Volumn 22, Issue 5, 1998, Pages 1132-1136

  Valenzuela, C Fernando ^a,c   Cardoso, Rita A ^a   Wick, Marilee J ^a,b   Weiner, Jeff L ^a   Dunwiddie, Thomas V ^a,b   Harris, R Adron ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

Ethanol; Glycine; Ion Channels; Patch Clamp; Phosphorylation

Indexed keywords

GLYCINE RECEPTOR;

ALCOHOL CONSUMPTION; ANIMAL CELL; ARTICLE; CELL POPULATION; FIBROBLAST; GENETIC RECOMBINATION; GENETIC TRANSFECTION; MAMMAL CELL; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; XENOPUS;

ANIMALIA; MAMMALIA;

EID: 0031703730     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1998.tb03712.x     Document Type: Article

References (10)

1. Rajendra S, Lynch JW, Schofield, PR: The glycine receptor. Pharmacol Ther 73:121-146, 1997
2. Celentano JJ, Gibbs TT, Farb DH: Ethanol potentiates GABA- and glycine-induced chloride currents in chick spinal cord neurons. Brain Res 455:377-380, 1988
3. - current by ethanol in cultured mouse spinal neurons. J Pharmacol Exp Ther 279:1116-1122, 1996
4. Mascia MP, Mihic SJ, Valenzuela CF, Schofield PR, Harris RA: A single amino acid determines differences in ethanol actions on strychnine-sensitive glycine receptors. Mol Pharmacol 50:402-406, 1996
5. Chen C, Okayama H: High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 7:2745-2752, 1987
6. Bormann J, Rundström N, Betz, H, Langosch, D: Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers. EMBO J 12:3729-3737, 1993
7. Yeh HH, Kolb JE: Ethanol modulation of GABA-activated current responses in acutely dissociated retinal bipolar cells and ganglion cells. Alcohol Clin Exp Res 21:647-655, 1997
8. A and glycine receptors. Nature 389:385-389, 1997
9. A receptors expressed in mammalian cells and Xenopus oocytes. Alcohol Clin Exp Res 21:444-451, 1997
10. Valenzuela CF, Harris RA: Alcohol: Neurobiology, in Lowinson JH, Ruiz P, Millman RB, Langrod JG (eds): Substance Abuse, ed. 3. Baltimore, Williams & Wilkins, 1997, pp 119-142