Acute effects of ethanol on recombinant kainate receptors: Lack of role of protein phosphorylation

Alcoholism: Clinical and Experimental Research

Volumn 22, Issue 6, 1998, Pages 1292-1299

  Valenzuela, C Fernando ^a,b   Cardoso, Rita A ^a   Lickteig, Ronald ^a   Browning, Michael D ^a   Nixon, Kristin M ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

Ethanol; Glutamate; Ion Channels; Kainate; Patch Clamp; Phosphorylation

Indexed keywords

ALCOHOL; ION CHANNEL; KAINIC ACID RECEPTOR; RECOMBINANT RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CHANNEL GATING; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; XENOPUS;

ANIMALIA;

EID: 0031693688     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1998.tb03911.x     Document Type: Article

References (36)

1. Hollmann M, Heinemann S: Cloned glutamate receptors. Ann Rev Neurosci 17:31-108, 1994
2. Petralia RS, Wang YX, Wenthold RJ: Histological and ultrastructural localization of the kainate receptor subunits, KA2 and GluR6/7, in the rat nervous system using selective antipeptide antibodies. J Comp Neurol 349:85-110, 1994
3. Donevan SD, Yamaguchi S, Rogawski MA: Non-N-methyl-D-aspartate receptor antagonism by 3-N-substituted 2,3-benzodiazepines: Relationship to anticonvulsant activity. J Pharmacol Exp Ther 271:25-29, 1994
4. Pelletier JC, Hesson DP, Jones KA, Costa AM: Substituted 1,2-dihydrophthalazines: Potent, selective, and noncompetitive inhibitors of the AMPA receptor. J Med Chem 39:343-346, 1996
5. Vignes M, Collingridge GL: The synaptic activation of kainate receptors. Nature 388:179-182, 1997
6. Castillo PE, Malenka RC, Nicoll RA: Kainate receptor mediate a slow postsynaptic current in hippocampal CA3 neurons. Nature 388:182-186, 1997
7. Rodriguez-Moreno A, Hcrreras O, Lerma J: Kainate receptors presynaptically downregulate GABAergic inhibition in the rat hippocampus. Neuron 19:893-901, 1997
8. Clarke VRJ, Ballyk BA, Hoo KH, Mandelzys A, Pellizari A, Bath CP, Thomas J, Sharpe EF, Davies CH, Ornstein PL, Schoepp DD, Kamboj RK, Collingridge GL, Lodge D, Bleakman D: A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission. Nature 389: 599-603, 1997
9. Wang LY, Taverna FA, Huang XP, MacDonald JF, Hampson DR: Phosphorylation and modulation of a kainate receptor (GluR6) by cAMP-dependent protein kinase. Science 259:1173-1175, 1993
10. Raymond LA, Blackstone CD, Huganir RL: Phosphorylation and modulation of recombinant GluR6 glutamate receptors by cAMP-dependent protein kinase. Nature 361:637-641, 1993
11. +/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors. Proc Natl Acad Sci USA 92:1376-1380, 1995
12. Dildy-Mayfield JE, Harris RA: Activation of protein kinase C inhibits kainate-induced currents in oocytes expressing glutamate receptor subunits. J Neurochem 62:1639-1642, 1994
13. Pickering DS, Taverna FA, Salter MW, Hampson DR: Palmitoylation of the GluR6 kainate receptor. Proc Natl Acad Sci USA 92:12090-12094, 1995
14. Dildy-Mayfield JE, Harris RA: Comparison of ethanol sensitivity of rat brain kainate, DL-alpha-amino-3-hydroxy-5-methyl-4-isoxalone proprionic acid and N-methyl-D-aspartate receptors expressed in Xenopus oocytes. J Pharmacol Exp Ther 262:487-494, 1992
15. Dildy-Mayfield JE, Harris RA: Acute and chronic ethanol exposure alters the function of hippocampal kainate receptors expressed in Xenopus oocytes. J Neurochem 58:1569-1572, 1992
16. Dildy-Mayfield JE, Harris RA: Ethanol inhibits kainate responses of glutamate receptors expressed in Xenopus oocytes: Role of calcium and protein kinase C. J Neurosci 15:3162-171, 1995
17. Dildy-Mayfield JE, Mihic SJ, Liu Y, Deitrich RA, Harris RA: Actions of long chain alcohols on GABAA and glutamate receptors: Relation to in vivo effects. Br J Pharmacol 118:378-384, 1996
18. Dildy-Mayfield JE, Eger EIn, Harris RA: Anesthetics produce subunit-selective actions on glutamate receptors. J Pharmacol Exp Ther 276:1058-1065, 1996
19. Harris RA, Mihic SJ, Dildy-Mayfield JE, Machu TK: Actions of anesthetics on ligand-gated ion channels: Role of receptor subunit com
20. position. FASEB J 9:1454-1462, 1995
21. Lovinger DM: High ethanol sensitivity of recombinant AMPA-type glutamate receptors expressed in mammalian cells. Neurosci Lett 159:83-87, 1993
22. Valenzuela CF, Harris RA: Alcohol: Neurobiology, ed 3. Baltimore, Williams & Wilkins, 1997
23. Weiner JL, Zhang L, Carlen PL: Potentiation of GABAA-mediated synaptic current by ethanol in hippocampal CA1 neurons: Possible role of protein kinase C. J Pharmacol Exp Ther 268:1388-1395, 1994
24. Weiner JL, Valenzuela CF, Watson PL, Frazier CJ, Dunwiddie TV: Elevation of basal protein kinase C activity increases ethanol sensitivity of GABA(A) receptors in rat hippocampal CA1 pyramidal neurons. J Neurochem 68:1949-1959, 1997
25. Harris RA, Mihic SJ, Brozowski S, Hadingham K, Whiting PJ: Ethanol, flunitrazepam, and pentobarbital modulation of GABAA receptors expressed in mammalian cells and Xenopus oocytes. Alcohol Clin Exp Res 21:444-451, 1997
26. Harris RA, McQuilkin SJ, Paylor R, et al: Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors. Proc Natl Acad Sci USA 92:3658-3662, 1995
27. Harris RA, Proctor WR, McQuilkin SJ, Klein RL, Mascia MP, Whatley V, Whiting PJ, Dunwiddie TV: Ethanol increases GABAA responses in cells stably transfected with receptor subunits. Alcohol Clin Exp Res 19:226-232, 1995
28. Snell LD, Tabakoff B, Hoffman PL: Involvement of protein kinase C in ethanol-induced inhibition of NMDA receptor function in cerebellar granule cells. Alcohol Clin Exp Res 18:81-85, 1994
29. Chen C, Okayama H: High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cel Biol 7:2745-2752, 1987
30. Valenzuela CF, Kazlauskas A, Brozowski SJ, Weiner JL, Demali KA, McDonald BJ, Moss SJ, Dunwiddie TV, Harris RA: Platelet-derived growth factor receptor is a novel modulator of type A gammaaminobutyric acid-gated ion channels. Mol Pharmacol 48:1099-1107, 1995
31. Lovinger DM: Developmental decrease in ethanol inhibition of N-methyl-D-aspartate receptors in rat neocortical neurons: Relation to the actions of ifenprodil. J Pharmacol Exp Ther 274:164-172, 1995
32. Chu B, Anantharam V, Treistman SN: Ethanol inhibition of recombinant heteromeric NMDA channels in the presence and absence of modulators. J Neurochem 65:140-148, 1995
33. Mirshahi T, Woodward JJ: Ethanol sensitivity of heteromeric NMDA receptors: Effects of subunit assembly, glycine and NMDAR1 Mg(2+)-insensitive mutants. Neuropharmacology 34:347-355, 1995
34. Lovinger DM: Alcohols and neurotransmitter gated ion channels: Past, present, and future. Naunyn Schmiedebergs Arch Pharmacol 356: 267-282, 1997
35. Miyakawa T, Yagi T, Kitazawa H, Yasuda M, Kawai N, Tsuboi K, Niki H: Fyn-kinase as a determinant of ethanol sensitivity: Relation to NMDA-receptor function. Science 278:698-701, 1997
36. Diamond I, Gordon AS: Cellular and molecular neuroscience of alcoholism. Physiol Rev 71:1-10, 1997