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Volumn 4, Issue 3, 1998, Pages 296-300

Hyperandrogenic anovulation (the polycystic ovary syndrome) - Back to the ovary?

Author keywords

Androgens; Body mass; Insulin; Polycystic ovary syndrome

Indexed keywords

ANDROGEN; CLOMIFENE CITRATE; FOLLITROPIN; INSULIN; LUTEINIZING HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

EID: 0031692127     PISSN: 13554786     EISSN: None     Source Type: Journal    
DOI: 10.1093/humupd/4.3.296     Document Type: Review
Times cited : (25)

References (39)
  • 1
    • 0022519137 scopus 로고
    • Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism
    • Adams, J., Poison, D.W. and Franks, S. (1986) Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism. Br. Med. J., 293, 355-359.
    • (1986) Br. Med. J. , vol.293 , pp. 355-359
    • Adams, J.1    Poison, D.W.2    Franks, S.3
  • 2
    • 0021637962 scopus 로고
    • Clomiphene citrate: Mechanism(s) and site(s) of action - A hypothesis revisited
    • Adashi, E.Y. (1984) Clomiphene citrate: mechanism(s) and site(s) of action - a hypothesis revisited. Fertil. Steril., 42, 331-344.
    • (1984) Fertil. Steril. , vol.42 , pp. 331-344
    • Adashi, E.Y.1
  • 3
    • 0029391136 scopus 로고
    • With a little help from my friends - The evolving story of intraovarian regulation
    • Adashi, E.Y. (1995) With a little help from my friends - the evolving story of intraovarian regulation. Endocrinology, 136, 4161-4162.
    • (1995) Endocrinology , vol.136 , pp. 4161-4162
    • Adashi, E.Y.1
  • 4
    • 0028151353 scopus 로고
    • A prospective study comparing unilateral and bilateral laparoscopic ovarian diathermy in women with the polycystic ovary syndrome
    • Balen, A.H. and Jacobs, H.S. (1994) A prospective study comparing unilateral and bilateral laparoscopic ovarian diathermy in women with the polycystic ovary syndrome. Fertil. Steril., 62, 921-925.
    • (1994) Fertil. Steril. , vol.62 , pp. 921-925
    • Balen, A.H.1    Jacobs, H.S.2
  • 5
    • 0024803403 scopus 로고
    • Quadruplets following cessation of clomiphene citrate: A case of sustained effect
    • Ben-Shlomo, I. and Zohar, S. (1989) Quadruplets following cessation of clomiphene citrate: a case of sustained effect. Acta Obstet. Gynecol. Scand., 68, 379-380.
    • (1989) Acta Obstet. Gynecol. Scand. , vol.68 , pp. 379-380
    • Ben-Shlomo, I.1    Zohar, S.2
  • 6
    • 0028896994 scopus 로고
    • Fertility, miscarriage and pregnancy after vertical banded gastroplasty operation for morbid obesity
    • Bilenka, B., Ben-Shlomo, I., Cozacov, C. et al. (1995) Fertility, miscarriage and pregnancy after vertical banded gastroplasty operation for morbid obesity. Acta Obstet. Gynecol. Scand., 74, 42-44.
    • (1995) Acta Obstet. Gynecol. Scand. , vol.74 , pp. 42-44
    • Bilenka, B.1    Ben-Shlomo, I.2    Cozacov, C.3
  • 7
    • 0027423114 scopus 로고
    • Estrogens inhibit and androgens enhance ovarian granulosa cell apoptosis
    • Billig, H., Furuta, I. and Hsueh, A.J. (1993) Estrogens inhibit and androgens enhance ovarian granulosa cell apoptosis. Endocrinology, 133, 2204-2212.
    • (1993) Endocrinology , vol.133 , pp. 2204-2212
    • Billig, H.1    Furuta, I.2    Hsueh, A.J.3
  • 9
    • 0024422033 scopus 로고
    • Regulation of prostaglandin endoperoxide synthase by cyclic adenosine 3',5'-monophosphate in the in vitro-perfused rat ovary
    • Brännstrom, M., Larson, L., Basta, B. and Hedin, L. (1989) Regulation of prostaglandin endoperoxide synthase by cyclic adenosine 3',5'-monophosphate in the in vitro-perfused rat ovary. Biol. Reprod., 41, 513-521.
    • (1989) Biol. Reprod. , vol.41 , pp. 513-521
    • Brännstrom, M.1    Larson, L.2    Basta, B.3    Hedin, L.4
  • 10
    • 0026587623 scopus 로고
    • Insulin and insuin growth factor-I responsiveness in polycystic ovarian syndrome
    • Buyalos, R.P., Geffner, M.E., Bersch, N. et al. (1992) Insulin and insuin growth factor-I responsiveness in polycystic ovarian syndrome. Fertil. Steril., 57, 796-803.
    • (1992) Fertil. Steril. , vol.57 , pp. 796-803
    • Buyalos, R.P.1    Geffner, M.E.2    Bersch, N.3
  • 11
    • 0027196489 scopus 로고
    • Evidence for a single gene effect causing polycystic ovaries and male pattern baldness
    • Carey, A.H., Chan, K.L., Short, F. et al. (1993) Evidence for a single gene effect causing polycystic ovaries and male pattern baldness. Clin. Endocrinol., 38, 653-658.
    • (1993) Clin. Endocrinol. , vol.38 , pp. 653-658
    • Carey, A.H.1    Chan, K.L.2    Short, F.3
  • 12
    • 0030918387 scopus 로고    scopus 로고
    • Leptin: A hormone of reproduction
    • Conway, G.S. and Jacobs, H.S. (1997) Leptin: a hormone of reproduction. Hum. Reprod., 12, 633-635.
    • (1997) Hum. Reprod. , vol.12 , pp. 633-635
    • Conway, G.S.1    Jacobs, H.S.2
  • 13
    • 0024542647 scopus 로고
    • Heterogeneity of the polycystic ovary syndrome: Clinical, endocrine and ultrasound features in 556 patients
    • Conway, G.S., Honour, J.W. and Jacobs, H.S. (1989) Heterogeneity of the polycystic ovary syndrome: clinical, endocrine and ultrasound features in 556 patients. Clin. Endocrinol., 30, 459-470.
    • (1989) Clin. Endocrinol. , vol.30 , pp. 459-470
    • Conway, G.S.1    Honour, J.W.2    Jacobs, H.S.3
  • 14
    • 0026781569 scopus 로고
    • Body weight, hyperinsulinemia, and gonadotropin levels in the polycystic ovarian syndrome: Evidence of two distinct populations
    • Dale, P.O., Tanbo, T., Vaaler, S. and Abyholm, T. (1992) Body weight, hyperinsulinemia, and gonadotropin levels in the polycystic ovarian syndrome: evidence of two distinct populations. Fertil. Steril., 58, 487-491.
    • (1992) Fertil. Steril. , vol.58 , pp. 487-491
    • Dale, P.O.1    Tanbo, T.2    Vaaler, S.3    Abyholm, T.4
  • 15
    • 0028909184 scopus 로고
    • Surgically induced ovulation in the polycystic ovary syndrome: Wedge resection revisited in the age of laparoscopy
    • Donesky, B.W. and Adashi, E.Y. (1995) Surgically induced ovulation in the polycystic ovary syndrome: wedge resection revisited in the age of laparoscopy. Fertil. Steril., 63, 439-463.
    • (1995) Fertil. Steril. , vol.63 , pp. 439-463
    • Donesky, B.W.1    Adashi, E.Y.2
  • 16
    • 0029119085 scopus 로고
    • Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome
    • Dunaif, A., Xia, J., Book, C.B., Schenker, E. et al. (1995) Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome. J. Clin. Invest., 96, 801-810
    • (1995) J. Clin. Invest. , vol.96 , pp. 801-810
    • Dunaif, A.1    Xia, J.2    Book, C.B.3    Schenker, E.4
  • 17
    • 0013472828 scopus 로고
    • Hirsutism
    • Studd, J. (ed.), Churchill Livingstone, London
    • Eden, J.A. (1994) Hirsutism. In Studd, J. (ed.), Progress in Obstetrics and Gynecology. Churchill Livingstone, London, Vol. 9, pp. 319-334.
    • (1994) Progress in Obstetrics and Gynecology , vol.9 , pp. 319-334
    • Eden, J.A.1
  • 18
    • 0031434341 scopus 로고    scopus 로고
    • The genetic basis of polycystic ovary syndrome
    • Franks, S., Gharani, N., Waterworth, D., Batty, S. et al. (1997) The genetic basis of polycystic ovary syndrome. Hum. Reprod., 12, 2641-2648.
    • (1997) Hum. Reprod. , vol.12 , pp. 2641-2648
    • Franks, S.1    Gharani, N.2    Waterworth, D.3    Batty, S.4
  • 20
    • 0021342161 scopus 로고
    • Polycystic ovarian syndrome treated by ovarian electrocautery through the laparoscope
    • Gjönnaess, H. (1984) Polycystic ovarian syndrome treated by ovarian electrocautery through the laparoscope. Fertil. Steril., 41, 20-25.
    • (1984) Fertil. Steril. , vol.41 , pp. 20-25
    • Gjönnaess, H.1
  • 21
    • 0030047163 scopus 로고    scopus 로고
    • Polycystic ovary syndrome - From gynaecological curiosity to multisystem endocrinopathy
    • Homburg, R. (1996) Polycystic ovary syndrome - from gynaecological curiosity to multisystem endocrinopathy. Hum. Reprod., 11, 29-39.
    • (1996) Hum. Reprod. , vol.11 , pp. 29-39
    • Homburg, R.1
  • 22
    • 0025266225 scopus 로고
    • Combined luteinizing hormone-releasing hormone analogue and exogenous gonadotrophins for the treatment of infertility associated with polycystic ovary syndrome
    • Homburg, R., Eshel, A., Kilborn, J. et al. (1990) Combined luteinizing hormone-releasing hormone analogue and exogenous gonadotrophins for the treatment of infertility associated with polycystic ovary syndrome. Hum. Reprod., 5, 32-35.
    • (1990) Hum. Reprod. , vol.5 , pp. 32-35
    • Homburg, R.1    Eshel, A.2    Kilborn, J.3
  • 23
    • 0025996188 scopus 로고
    • Pathophysiology of polycystic ovarian disease: New insights
    • Insler, V. and Lunenfeld, B. (1991) Pathophysiology of polycystic ovarian disease: new insights. Hum. Reprod., 6, 1025-1029.
    • (1991) Hum. Reprod. , vol.6 , pp. 1025-1029
    • Insler, V.1    Lunenfeld, B.2
  • 24
    • 0017097962 scopus 로고
    • The effects of ovarian wedge resection on circulating gonadotropin and ovarian steroid levels in patients with polycystic ovary syndrome
    • Judd, H.L., Rigg, L.A., Anderson, D.C. and Yen, S.S.C. (1976) The effects of ovarian wedge resection on circulating gonadotropin and ovarian steroid levels in patients with polycystic ovary syndrome. J. Clin. Endocrinol. Metab., 43, 347-355.
    • (1976) J. Clin. Endocrinol. Metab. , vol.43 , pp. 347-355
    • Judd, H.L.1    Rigg, L.A.2    Anderson, D.C.3    Yen, S.S.C.4
  • 25
    • 0017815297 scopus 로고
    • Hormonal effects of wedge resection of polycystic ovaries
    • Katz, M., Carr, P.J., Cohen, B.M. and Millar, R.P. (1978) Hormonal effects of wedge resection of polycystic ovaries. Obstet. Gynecol., 51, 437-444.
    • (1978) Obstet. Gynecol. , vol.51 , pp. 437-444
    • Katz, M.1    Carr, P.J.2    Cohen, B.M.3    Millar, R.P.4
  • 26
    • 0017154704 scopus 로고
    • The syndromes of insulin resistance and acanthosis nigricans: Insulin receptor disorders in man
    • Khan, C.R., Flier, J.S., Bar, R.S. et al. (1976) The syndromes of insulin resistance and acanthosis nigricans: insulin receptor disorders in man. N. Eng. J. Med., 294, 739-745.
    • (1976) N. Eng. J. Med. , vol.294 , pp. 739-745
    • Khan, C.R.1    Flier, J.S.2    Bar, R.S.3
  • 27
    • 0026543775 scopus 로고
    • Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome
    • Kiddy, D.S., Hamilton-Fairley, D., Bush, A. et al. (1992) Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome. Clin. Endocrinol., 36, 105-111.
    • (1992) Clin. Endocrinol. , vol.36 , pp. 105-111
    • Kiddy, D.S.1    Hamilton-Fairley, D.2    Bush, A.3
  • 28
    • 0030973189 scopus 로고    scopus 로고
    • Interleukin-1-dependent regulation of glucose transporters in the immature rat ovary: A specific receptor-mediated effect
    • Kol, S., Ben-Shlomo, I., Ruutiainen, K. et al. (1997) Interleukin-1-dependent regulation of glucose transporters in the immature rat ovary: a specific receptor-mediated effect. J. Clin. Invest., 99, 2274-2283.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2274-2283
    • Kol, S.1    Ben-Shlomo, I.2    Ruutiainen, K.3
  • 29
    • 0025268241 scopus 로고
    • Insulin secretion in polycystic ovarian disease: Effect of ovarian suppression by GnRH agonist
    • Lanzone, A., Fulghesu, A.M., Andreani, C.L. et al. (1990) Insulin secretion in polycystic ovarian disease: effect of ovarian suppression by GnRH agonist. Hum. Reprod., 5, 143-149.
    • (1990) Hum. Reprod. , vol.5 , pp. 143-149
    • Lanzone, A.1    Fulghesu, A.M.2    Andreani, C.L.3
  • 30
    • 0026763156 scopus 로고
    • Ovarian hyperstimulation syndrome in novel reproductive technologies: Prevention and treatment
    • Navot, D., Bergh, P.A. and Laufer, N. (1992) Ovarian hyperstimulation syndrome in novel reproductive technologies: prevention and treatment. Fertil. Steril., 58, 249-261.
    • (1992) Fertil. Steril. , vol.58 , pp. 249-261
    • Navot, D.1    Bergh, P.A.2    Laufer, N.3
  • 31
    • 0029796476 scopus 로고    scopus 로고
    • Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome
    • Nestler, J.E. and Jakubowicz, D.J. (1996) Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome. N. Eng. J. Med., 335, 617-623.
    • (1996) N. Eng. J. Med. , vol.335 , pp. 617-623
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 32
    • 0023879442 scopus 로고
    • Polycystic ovaries - A common finding in normal women
    • Polson, D.W., Adams, J., Wadsworth, J. and Franks, S. (1988) Polycystic ovaries - a common finding in normal women. Lancet, 1, 870-872.
    • (1988) Lancet , vol.1 , pp. 870-872
    • Polson, D.W.1    Adams, J.2    Wadsworth, J.3    Franks, S.4
  • 33
    • 0025195368 scopus 로고
    • Dysregulation of cytochrome P450c 17 alpha as the cause of polycystic ovarian syndrome
    • Rosenfield, R.L., Barnes, R.B., Cara, J.F. and Lucky, A.W. (1990) Dysregulation of cytochrome P450c 17 alpha as the cause of polycystic ovarian syndrome. Fertil. Steril., 53, 785-791.
    • (1990) Fertil. Steril. , vol.53 , pp. 785-791
    • Rosenfield, R.L.1    Barnes, R.B.2    Cara, J.F.3    Lucky, A.W.4
  • 34
    • 0017658873 scopus 로고
    • Increasing ovulation rate in sheep by active immunisation against an ovarian steroid androstenedione
    • Scaramuzzi, R.J., Davidson, W.G. and Van-Look, P.F.A. (1977) Increasing ovulation rate in sheep by active immunisation against an ovarian steroid androstenedione. Nature, 269, 817-818.
    • (1977) Nature , vol.269 , pp. 817-818
    • Scaramuzzi, R.J.1    Davidson, W.G.2    Van-Look, P.F.A.3
  • 35
    • 0001698606 scopus 로고
    • Amenorrhea associated with bilateral polycystic ovaries
    • Stein, I.F. and Leventhal, M.L. (1935) Amenorrhea associated with bilateral polycystic ovaries. Am. J. Obstet. Gynecol., 29, 181-191.
    • (1935) Am. J. Obstet. Gynecol. , vol.29 , pp. 181-191
    • Stein, I.F.1    Leventhal, M.L.2
  • 36
    • 0015810938 scopus 로고
    • Effect of anti-estrogenic action of clomiphene during the menstrual cycle: Evidence for a change in the feedback sensitivity
    • Van den Berg, G. and Yen, S.S.C. (1973) Effect of anti-estrogenic action of clomiphene during the menstrual cycle: evidence for a change in the feedback sensitivity. J. Clin. Endocrinol. Metab., 37, 356-365.
    • (1973) J. Clin. Endocrinol. Metab. , vol.37 , pp. 356-365
    • Van Den Berg, G.1    Yen, S.S.C.2
  • 37
    • 0018847979 scopus 로고
    • The use of human gonadotropin for the induction of ovulation in women with polycystic ovarian disease
    • Wang, C.F. and Gemzell, C. (1980) The use of human gonadotropin for the induction of ovulation in women with polycystic ovarian disease. Fertil. Steril., 33, 479-486.
    • (1980) Fertil. Steril. , vol.33 , pp. 479-486
    • Wang, C.F.1    Gemzell, C.2
  • 38
    • 0028823250 scopus 로고
    • Insulin action in human granulosa cells from normal and polycystic ovaries is mediated the insulin receptor and not the type-I insulin-like growth factor receptor
    • Willis, D. and Franks, S. (1995) Insulin action in human granulosa cells from normal and polycystic ovaries is mediated the insulin receptor and not the type-I insulin-like growth factor receptor. J. Clin. Endocrinol. Metab., 80, 3788-3790.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 3788-3790
    • Willis, D.1    Franks, S.2
  • 39
    • 0030046499 scopus 로고    scopus 로고
    • Modulation by insulin of follicle-stimulating hormone and luteinizing hormone actions in human granulosa cells of normal and polycystic ovaries
    • Willis, D., Mason, H., Gilling-Smith, C. and Franks, S. (1996) Modulation by insulin of follicle-stimulating hormone and luteinizing hormone actions in human granulosa cells of normal and polycystic ovaries. J. Clin. Endocrinol. Metab., 81, 302-309.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 302-309
    • Willis, D.1    Mason, H.2    Gilling-Smith, C.3    Franks, S.4


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