Immune reactivity to proteins biotransformed by alcohol metabolites

Alcoholism: Clinical and Experimental Research

Volumn 22, Issue 5 SUPPL., 1998, Pages

  Klassen, Lynell W ^a   Thiele, Geoffrey M ^b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL CONSUMPTION; ALCOHOLISM; BIOTRANSFORMATION; CONFERENCE PAPER; HUMAN; HUMORAL IMMUNITY; IMMUNOREACTIVITY; PRIORITY JOURNAL;

EID: 0031685776     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1998.tb04002.x     Document Type: Conference Paper

References (15)

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9. Tuma DJ, Thiele GM, Xu D, Klassen LW, Sorrell MF: Acetaldehyde and malondialdehyde react together to generate distinct protein adducts in the liver during long-term ethanol administration. Hepatology 23:872-880, 1996
10. Willis MS, Tuma DJ, McDonald TL, et al: Soluble proteins modified with acetaldehyde and malondialdehyde become immunogenic. Alcohol Clin Exp Res 20(Suppl.):120A, 1996 (abstract)
11. Xu DS, Thiele GM, Beckenhauer JL, et al: Detection of circulating antibodies to malondialdehyde-acetaldehyde (MAA) adducts in ethanolfed rats. Hepatology 26:271A, 1997 (abstract)
12. Thiele GM, Tuma DJ, Willis MS, Miller JA, McDonald TL, Sorrel MF, Klassen LW: Soluble proteins modified with acetaldehyde and malondialdehyde are immunogenic in the absence of adjuvant. Alcohol Clin Exp Res (in press)
13. Thiele GM, Klassen LW, Miller JA, et al: Binding of aldehyde-modified proteins to liver endothelial cells changes the adhesion molecule and TNF-alpha expression. J Allergy Clin Immunol 99:S195, 1997 (abstract)
14. Miller JA, Klassen LW, Duryee MJ, et al: Increased adhesion molecule and TNF-alpha expression by liver endothelial cells after exposure to MAA-modified proteins. Hepatology 26:330A, 1997 (abstract)
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