메뉴 건너뛰기




Volumn 33, Issue 5, 1998, Pages 618-624

Roles of COX-1 and COX-2 in gastrointestinal pathophysiology

Author keywords

Colon cancer; Cyclooxygenase; Gastric ulcer; Prostaglandin

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GROWTH FACTOR; MESSENGER RNA; PROSTAGLANDIN;

EID: 0031659396     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350050147     Document Type: Review
Times cited : (50)

References (68)
  • 1
    • 0018637521 scopus 로고
    • Protection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury
    • Rokert A, Nezamis JE, Lancaster C, et al. Protection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury. Gastroenterology 1979;77:433-443.
    • (1979) Gastroenterology , vol.77 , pp. 433-443
    • Rokert, A.1    Nezamis, J.E.2    Lancaster, C.3
  • 2
    • 0023106491 scopus 로고
    • Prostaglandin protects against taurocholate-induced damage to rat gastric mucosal cell culture
    • Terano A, Ota S, Mach T, et al. Prostaglandin protects against taurocholate-induced damage to rat gastric mucosal cell culture. Gastroenterology 1986;92:669-677.
    • (1986) Gastroenterology , vol.92 , pp. 669-677
    • Terano, A.1    Ota, S.2    Mach, T.3
  • 3
    • 0025641673 scopus 로고
    • Prostaglandin protects isolated guinea pig chief cells against ethanol injury via an increase in diacylglycerol
    • Konda Y, Nishisaki H, Nakano O, et al. Prostaglandin protects isolated guinea pig chief cells against ethanol injury via an increase in diacylglycerol. J Clin Invest 1990;86:1897-1903.
    • (1990) J Clin Invest , vol.86 , pp. 1897-1903
    • Konda, Y.1    Nishisaki, H.2    Nakano, O.3
  • 4
    • 0018292487 scopus 로고
    • Cytoprotection by prostaglandins
    • Robert A. Cytoprotection by prostaglandins. Gastroenterology 1979;77:761-767.
    • (1979) Gastroenterology , vol.77 , pp. 761-767
    • Robert, A.1
  • 5
    • 0030338041 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drug gastropathy; causes and treatment
    • Hawkey CJ. Non-steroidal anti-inflammatory drug gastropathy; causes and treatment. Scand J Gastroenterol 1996;31(Suppl 220):124-127.
    • (1996) Scand J Gastroenterol , vol.31 , Issue.220 SUPPL. , pp. 124-127
    • Hawkey, C.J.1
  • 6
    • 0029557201 scopus 로고
    • Non-steroidal anti-inflammatory drug-induced gastric damage in experimental animals: Unerlying pathological mechanism
    • Trevethick MA, Oakely I, Clayton NM, et al. Non-steroidal anti-inflammatory drug-induced gastric damage in experimental animals: Unerlying pathological mechanism. Gen Pharmacol 1995;26:1455-1459.
    • (1995) Gen Pharmacol , vol.26 , pp. 1455-1459
    • Trevethick, M.A.1    Oakely, I.2    Clayton, N.M.3
  • 7
    • 0027944075 scopus 로고
    • Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
    • Seribert K, Zhang Y, Leahy K, et al. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci USA 1994;91:12013-12017.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12013-12017
    • Seribert, K.1    Zhang, Y.2    Leahy, K.3
  • 8
    • 0028843881 scopus 로고
    • Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
    • Langenbach R, Morham SG, Tiano HF, et al. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 1995;83:483-492.
    • (1995) Cell , vol.83 , pp. 483-492
    • Langenbach, R.1    Morham, S.G.2    Tiano, H.F.3
  • 9
    • 0023687241 scopus 로고
    • Colorectal cancer risk, chronic illness, operations, and medications: Case control results from the Melbourne Colorectal Cancer Study
    • Kune GA, Kune S, Watson LF. Colorectal cancer risk, chronic illness, operations, and medications: Case control results from the Melbourne Colorectal Cancer Study. Cancer 1988;48:4399-4404.
    • (1988) Cancer , vol.48 , pp. 4399-4404
    • Kune, G.A.1    Kune, S.2    Watson, L.F.3
  • 10
    • 0026417761 scopus 로고
    • A hypothesis: Non-steroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer
    • Rosènberg L, Palmer JR, Zauber AG, et al. A hypothesis: Non-steroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer. J Natl Cancer Inst 1991;83:355-358.
    • (1991) J Natl Cancer Inst , vol.83 , pp. 355-358
    • Rosènberg, L.1    Palmer, J.R.2    Zauber, A.G.3
  • 11
    • 0025744852 scopus 로고
    • Aspirin use and incidence of large-bowel cancer in a California retirement community
    • Paganini-Hill A, Hsu G, Ross RK, et at. Aspirin use and incidence of large-bowel cancer in a California retirement community. J Natl Cancer Inst 1991;83:1182-1183.
    • (1991) J Natl Cancer Inst , vol.83 , pp. 1182-1183
    • Paganini-Hill, A.1    Hsu, G.2    Ross, R.K.3
  • 12
    • 0025998557 scopus 로고
    • Aspirin use and reduced risk of fetal colon cancer
    • Thun MJ, Namboodiri MM, Heath CW Jr. Aspirin use and reduced risk of fetal colon cancer. N Engl J Med 1991;325:1593-1596.
    • (1991) N Engl J Med , vol.325 , pp. 1593-1596
    • Thun, M.J.1    Namboodiri, M.M.2    Heath Jr., C.W.3
  • 13
    • 0029008617 scopus 로고
    • Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer
    • Kargman SL, O'Neill GP, Vickers PJ, et al. Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Res 1995;55:2556-2559.
    • (1995) Cancer Res , vol.55 , pp. 2556-2559
    • Kargman, S.L.1    O'Neill, G.P.2    Vickers, P.J.3
  • 14
    • 0029117472 scopus 로고
    • Expression of cyclooxygenase-1 and -2 in human colorectal cancer
    • Sano H, Kawahito Y, Wilder RL, et al. Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res 1995; 55:3785-3789.
    • (1995) Cancer Res , vol.55 , pp. 3785-3789
    • Sano, H.1    Kawahito, Y.2    Wilder, R.L.3
  • 15
    • 0029913633 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors
    • DuBois RN, Radhika A, Reddy BS, et al. Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors. Gastroenterology 1996;110:1259-1262.
    • (1996) Gastroenterology , vol.110 , pp. 1259-1262
    • DuBois, R.N.1    Radhika, A.2    Reddy, B.S.3
  • 16
    • 0030071213 scopus 로고    scopus 로고
    • Cyclooxygenase-1 and cyclooxygenase-2 gene expression in human colorectal adenocarcinomas and in azoxymethane induced colonic tumours in rats
    • Gustafson-Svärd C, Lilja I, Haliböök O, et al. Cyclooxygenase-1 and cyclooxygenase-2 gene expression in human colorectal adenocarcinomas and in azoxymethane induced colonic tumours in rats. Gut 1996;38:79-84.
    • (1996) Gut , vol.38 , pp. 79-84
    • Gustafson-Svärd, C.1    Lilja, I.2    Haliböök, O.3
  • 17
    • 0023968630 scopus 로고
    • Primary structure of prostagiandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence
    • DeWitt DL, Smith WL. Primary structure of prostagiandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc Natl Acad Sci USA 1988;85:1412-1416.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1412-1416
    • DeWitt, D.L.1    Smith, W.L.2
  • 18
    • 0023855416 scopus 로고
    • Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (Cyclooxygenase)
    • Merlie JP, Fagan D, Mudd J, et al. Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (Cyclooxygenase). J Biol Chem 1988;263:3550-3553.
    • (1988) J Biol Chem , vol.263 , pp. 3550-3553
    • Merlie, J.P.1    Fagan, D.2    Mudd, J.3
  • 19
    • 0023915232 scopus 로고
    • Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence
    • Yokoyama C, Takai T, Tanabe T. Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence. FEBS Lett 1988;231:347-351.
    • (1988) FEBS Lett , vol.231 , pp. 347-351
    • Yokoyama, C.1    Takai, T.2    Tanabe, T.3
  • 20
    • 0025248570 scopus 로고
    • The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases
    • DeWitt DL, El-Harith EA, Kraemer SA, et al. The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases. J Biol Chem 1990;265:5192-5198.
    • (1990) J Biol Chem , vol.265 , pp. 5192-5198
    • DeWitt, D.L.1    El-Harith, E.A.2    Kraemer, S.A.3
  • 21
    • 0025909387 scopus 로고
    • Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment
    • Funk CD, Funk LB, Kennedy ME, et al. Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment. FASEB J 1991;5:2304-2312.
    • (1991) FASEB J , vol.5 , pp. 2304-2312
    • Funk, C.D.1    Funk, L.B.2    Kennedy, M.E.3
  • 22
    • 0026588059 scopus 로고
    • Prostaglandin endoperoxide synthase gene structure: Identification of the transcriptional start site and 5′-flanking regulatory sequences 1
    • Kraemer SA, Meade EA, DeWitt DL. Prostaglandin endoperoxide synthase gene structure: Identification of the transcriptional start site and 5′-flanking regulatory sequences 1. Arch Biochem Biophys 1992;293:391-400.
    • (1992) Arch Biochem Biophys , vol.293 , pp. 391-400
    • Kraemer, S.A.1    Meade, E.A.2    DeWitt, D.L.3
  • 23
    • 0024818522 scopus 로고
    • Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme
    • Yokoyama C, Tanabe T. Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme. Bichem Biophys Res Commun 1989;165:888-894.
    • (1989) Bichem Biophys Res Commun , vol.165 , pp. 888-894
    • Yokoyama, C.1    Tanabe, T.2
  • 24
    • 0001208476 scopus 로고
    • Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases
    • Raz A, Wyche A, Needleman P. Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases. Proc Natl Acad Sci USA 1989;86:1657-1661.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1657-1661
    • Raz, A.1    Wyche, A.2    Needleman, P.3
  • 26
    • 0025187588 scopus 로고
    • Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice
    • Masferrer JL, Zweifel BS, Seibert K, et al. Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice. J Clin Invest 1990;86:1375-1379.
    • (1990) J Clin Invest , vol.86 , pp. 1375-1379
    • Masferrer, J.L.1    Zweifel, B.S.2    Seibert, K.3
  • 27
    • 0025754779 scopus 로고
    • Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
    • Xie W, Chipman JG, Robertson DL, et al. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 1991;88:2692-2696.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2692-2696
    • Xie, W.1    Chipman, J.G.2    Robertson, D.L.3
  • 28
    • 0025871150 scopus 로고
    • TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
    • Kujubu DA, Fletcher BS, Varnum BC, et al. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem 1991;266:12866-12872.
    • (1991) J Biol Chem , vol.266 , pp. 12866-12872
    • Kujubu, D.A.1    Fletcher, B.S.2    Varnum, B.C.3
  • 29
    • 0026735231 scopus 로고
    • cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase
    • O'Banion MK, Winn VD, Young DA. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc Natl Acad Sci USA 1992;89:4888-4892.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4888-4892
    • O'Banion, M.K.1    Winn, V.D.2    Young, D.A.3
  • 30
    • 0028145016 scopus 로고
    • Transforming growth factor beta 1 augments mitogen-induced prostaglandin synthesis and expression of the TIS10/prostaglandin synthase 2 gene both in Swiss 3T3 cells and in murine embryo fibroblasts
    • Gilbert RS, Reddy ST, Kujubu DA, et al. Transforming growth factor beta 1 augments mitogen-induced prostaglandin synthesis and expression of the TIS10/prostaglandin synthase 2 gene both in Swiss 3T3 cells and in murine embryo fibroblasts. J Cell Physiol 1994;159:67-75.
    • (1994) J Cell Physiol , vol.159 , pp. 67-75
    • Gilbert, R.S.1    Reddy, S.T.2    Kujubu, D.A.3
  • 31
    • 0027468941 scopus 로고
    • Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines
    • Jones DA, Carlton DP, McIntyre TM, et al. Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J Biol Chem 1993;268:9049-9054.
    • (1993) J Biol Chem , vol.268 , pp. 9049-9054
    • Jones, D.A.1    Carlton, D.P.2    McIntyre, T.M.3
  • 32
    • 0028199075 scopus 로고
    • Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages
    • Reddy ST, Herschman HR. Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages. J Biol Chem 1994;269:15473-15480.
    • (1994) J Biol Chem , vol.269 , pp. 15473-15480
    • Reddy, S.T.1    Herschman, H.R.2
  • 33
    • 0028107128 scopus 로고
    • Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes
    • Hempel SL, Monick MM, Hunninghake GW. Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes. J Clin Invest 1994;93:391-396.
    • (1994) J Clin Invest , vol.93 , pp. 391-396
    • Hempel, S.L.1    Monick, M.M.2    Hunninghake, G.W.3
  • 34
    • 0028366113 scopus 로고
    • Induction of cyclooxygenase-2 in rat vascular smooth muscle cells in vitro and in vivo
    • Pritchard KA Jr, O'Banion MK, Miano JM, et al. Induction of cyclooxygenase-2 in rat vascular smooth muscle cells in vitro and in vivo. J Biol Chem 1994;269:8504-8509.
    • (1994) J Biol Chem , vol.269 , pp. 8504-8509
    • Pritchard Jr., K.A.1    O'Banion, M.K.2    Miano, J.M.3
  • 35
    • 0028213334 scopus 로고
    • Cyclooxygenase-1 and -2 expression in rheumatoid tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids
    • Crofford LJ, Wilder RL, Ristimäki AP, et al. Cyclooxygenase-1 and -2 expression in rheumatoid tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids. J Clin Invest 1994; 94:1095-1101.
    • (1994) J Clin Invest , vol.94 , pp. 1095-1101
    • Crofford, L.J.1    Wilder, R.L.2    Ristimäki, A.P.3
  • 36
    • 0027491581 scopus 로고
    • Differential regulation of inducible and constitutive prostaglandin endooperoxide synthase in osteoblastic MC3T3-E1 cells
    • Pilbeam CC, Kawaguchi H, Hakeda Y, et al. Differential regulation of inducible and constitutive prostaglandin endooperoxide synthase in osteoblastic MC3T3-E1 cells. J Biol Chem 1993;268:25643-25649.
    • (1993) J Biol Chem , vol.268 , pp. 25643-25649
    • Pilbeam, C.C.1    Kawaguchi, H.2    Hakeda, Y.3
  • 37
    • 0028107576 scopus 로고
    • Regulation of prostaglandin endoperoxide synthase gene expression in rat mesangial cell by interleukin-1 beta
    • Rzymkiewicz D, Leingang K, Baird N, et al. Regulation of prostaglandin endoperoxide synthase gene expression in rat mesangial cell by interleukin-1 beta. Am J Physiol 1994;266:F39-F45.
    • (1994) Am J Physiol , vol.266
    • Rzymkiewicz, D.1    Leingang, K.2    Baird, N.3
  • 38
    • 0028290632 scopus 로고
    • Cloning and characterization of a growth factor-inducible cyclooxygenase gene from rat intestinal epithelial cells
    • DuBois RN, Tsujii M, Bishop P, et al. Cloning and characterization of a growth factor-inducible cyclooxygenase gene from rat intestinal epithelial cells. Am J Physiol 1994;266:G822-G827.
    • (1994) Am J Physiol , vol.266
    • DuBois, R.N.1    Tsujii, M.2    Bishop, P.3
  • 39
    • 0028344102 scopus 로고
    • Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester
    • DuBois RN, Awad J, Morrow J, et al. Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester. J Clin Invest 1994;93:493-498.
    • (1994) J Clin Invest , vol.93 , pp. 493-498
    • DuBois, R.N.1    Awad, J.2    Morrow, J.3
  • 40
    • 0030895087 scopus 로고    scopus 로고
    • Crypt stem cell survival in the mouse intestinal epithelium is regulated by prostaglandins synthesized through cyclooxygenase-1
    • Conn SM, Schloemann S, Tessner T, et al. Crypt stem cell survival in the mouse intestinal epithelium is regulated by prostaglandins synthesized through cyclooxygenase-1. J Clin Invest 1997;99: 1367-1379.
    • (1997) J Clin Invest , vol.99 , pp. 1367-1379
    • Conn, S.M.1    Schloemann, S.2    Tessner, T.3
  • 41
    • 0030744590 scopus 로고    scopus 로고
    • Cyclooxygenase-1 behaves as a delayed response gene in PC12 cells differentiated by nerve growth factor
    • Kaplan MD, Olschowka JA, O'Banion MK. Cyclooxygenase-1 behaves as a delayed response gene in PC12 cells differentiated by nerve growth factor. J Biol Chem 1997;272:18534-18537.
    • (1997) J Biol Chem , vol.272 , pp. 18534-18537
    • Kaplan, M.D.1    Olschowka, J.A.2    O'Banion, M.K.3
  • 42
    • 0021906869 scopus 로고
    • Determination of the structure of the carbohydrate chains of prostaglandin endoperoxide from sheep
    • Mutsaers JHGM, van Halbeek H, Kamerling JP, et al. Determination of the structure of the carbohydrate chains of prostaglandin endoperoxide from sheep. Eur J Biochem 1985;147:569-574.
    • (1985) Eur J Biochem , vol.147 , pp. 569-574
    • Mutsaers, J.H.G.M.1    Van Halbeek, H.2    Kamerling, J.P.3
  • 43
    • 0026508844 scopus 로고
    • Tyrosyl radicals and their role in hydroperoxide-dependent activation and inactivation of prostaglandin endoperoxide synthase
    • Smith WL, Eling TE, Kulmacz RJ, et al. Tyrosyl radicals and their role in hydroperoxide-dependent activation and inactivation of prostaglandin endoperoxide synthase. Biochemistry 1992;39:3-7.
    • (1992) Biochemistry , vol.39 , pp. 3-7
    • Smith, W.L.1    Eling, T.E.2    Kulmacz, R.J.3
  • 44
    • 0025728865 scopus 로고
    • Prostaglandin endoperoxide synthase: Structure and catalysis
    • Smith WL, Marnett LJ. Prostaglandin endoperoxide synthase: Structure and catalysis. Biochem Biophys Acta 1991;1083:1-17.
    • (1991) Biochem Biophys Acta , vol.1083 , pp. 1-17
    • Smith, W.L.1    Marnett, L.J.2
  • 45
    • 0019186365 scopus 로고
    • Acetylation of prostaglandin endoperoxide synthetase with acetylsalicylic acid
    • van der Ouderaa FJ, Buytenhek M, Nugteren DH, et al. Acetylation of prostaglandin endoperoxide synthetase with acetylsalicylic acid. Eur J Biochem 1980;109:1-8.
    • (1980) Eur J Biochem , vol.109 , pp. 1-8
    • Van Der Ouderaa, F.J.1    Buytenhek, M.2    Nugteren, D.H.3
  • 46
    • 0028339780 scopus 로고
    • Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
    • Lecomte M, Laneuville Q, Ji C, et al. Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin. J Biol Chem 1994;269:13207-13215.
    • (1994) J Biol Chem , vol.269 , pp. 13207-13215
    • Lecomte, M.1    Laneuville, Q.2    Ji, C.3
  • 47
  • 48
    • 0030017042 scopus 로고    scopus 로고
    • Characterization of prostaglandin G/H synthase 1 and 2 in rat, dog, monkey, and human gastrointesinal tracts
    • Kargman S, Charleson S, Cartwright M, et al. Characterization of prostaglandin G/H synthase 1 and 2 in rat, dog, monkey, and human gastrointesinal tracts. Gastroenterology 1996;111:445-454.
    • (1996) Gastroenterology , vol.111 , pp. 445-454
    • Kargman, S.1    Charleson, S.2    Cartwright, M.3
  • 49
    • 0028322893 scopus 로고
    • Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic
    • Masferrer JL, Zweifel BS, Manning PT, et al. Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc Natl Acad Sci USA 1994;911:3228-3232.
    • (1994) Proc Natl Acad Sci USA , vol.911 , pp. 3228-3232
    • Masferrer, J.L.1    Zweifel, B.S.2    Manning, P.T.3
  • 50
    • 0029028590 scopus 로고
    • Immunocytochemical localization of cyclooxygenase-1 and cyclooxygenase-2 in the rat stomach
    • Iseki S. Immunocytochemical localization of cyclooxygenase-1 and cyclooxygenase-2 in the rat stomach. Histochem J 1995; 27:323-328.
    • (1995) Histochem J , vol.27 , pp. 323-328
    • Iseki, S.1
  • 51
    • 0023877846 scopus 로고
    • Role of epidermal growth factor in healing of chronic gastroduodenal ulcers in rats
    • Konturek SJ, Dembinski A, Warzecha Z, et al. Role of epidermal growth factor in healing of chronic gastroduodenal ulcers in rats. Gastroenterology 1988;944:1300-1307.
    • (1988) Gastroenterology , vol.944 , pp. 1300-1307
    • Konturek, S.J.1    Dembinski, A.2    Warzecha, Z.3
  • 52
    • 0022930460 scopus 로고
    • 2 in cloned osteoblastic cells of mouse (MC3T3-E1) by epidermal growth factor
    • 2 in cloned osteoblastic cells of mouse (MC3T3-E1) by epidermal growth factor. J Biol Chem 1986;2261:15410-15415.
    • (1986) J Biol Chem , vol.2261 , pp. 15410-15415
    • Yokota, K.1    Kusaka, M.2    Ohoshima, T.3
  • 54
    • 0029162597 scopus 로고
    • 2 release by epidermal growth factor in cultured guinea pig gastric mucous cells
    • 2 release by epidermal growth factor in cultured guinea pig gastric mucous cells. Dig Dis Sci 1995;40:1679-1686.
    • (1995) Dig Dis Sci , vol.40 , pp. 1679-1686
    • Nakano, S.1    Sakamoto, C.2    Matsuda, K.3
  • 55
    • 0028807498 scopus 로고
    • Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
    • Morham S, Langenbach R, Loftin CD, et al. Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 1995;83:473-482.
    • (1995) Cell , vol.83 , pp. 473-482
    • Morham, S.1    Langenbach, R.2    Loftin, C.D.3
  • 56
    • 0031052116 scopus 로고    scopus 로고
    • Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice
    • Mizuno H, Sakamoto C, Matsuda K, et al. Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. Gastroenterology 1997;112:387-397.
    • (1997) Gastroenterology , vol.112 , pp. 387-397
    • Mizuno, H.1    Sakamoto, C.2    Matsuda, K.3
  • 57
    • 0031575424 scopus 로고    scopus 로고
    • Quantitative analysis of cyclooxygenase-2 gene expression on acute gastric injury induced by ischemia-reperfusion in rats
    • Kishimoto Y, Wada K, Nakamoto K, et al. Quantitative analysis of cyclooxygenase-2 gene expression on acute gastric injury induced by ischemia-reperfusion in rats. Life Sci 1997;60:127-133.
    • (1997) Life Sci , vol.60 , pp. 127-133
    • Kishimoto, Y.1    Wada, K.2    Nakamoto, K.3
  • 58
    • 0029852719 scopus 로고    scopus 로고
    • Hepatocyte growth factor as a key to modulate anti-ulcer action of prostaglandins in stomach
    • Takahashi M, Ota S, Hata Y, et al. Hepatocyte growth factor as a key to modulate anti-ulcer action of prostaglandins in stomach. J Clin Invest 1996;98:2604-2611.
    • (1996) J Clin Invest , vol.98 , pp. 2604-2611
    • Takahashi, M.1    Ota, S.2    Hata, Y.3
  • 59
    • 0029907525 scopus 로고    scopus 로고
    • Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2
    • Reuter BK, Asfaha S, Buret A, et al. Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2. J Clin Invest 1996;98:2076-2085.
    • (1996) J Clin Invest , vol.98 , pp. 2076-2085
    • Reuter, B.K.1    Asfaha, S.2    Buret, A.3
  • 60
    • 0028904461 scopus 로고
    • Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent
    • Rao CV, Rivenson A, Simi B, et al. Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent. Cancer Res 1995;55:1464-1472.
    • (1995) Cancer Res , vol.55 , pp. 1464-1472
    • Rao, C.V.1    Rivenson, A.2    Simi, B.3
  • 61
    • 0020565187 scopus 로고
    • Sulindac for polyposis of the colon
    • Waddell WR, Loughry RW. Sulindac for polyposis of the colon. J Surg Oncol 1983;24:83-87.
    • (1983) J Surg Oncol , vol.24 , pp. 83-87
    • Waddell, W.R.1    Loughry, R.W.2
  • 62
  • 63
    • 0026316148 scopus 로고
    • Effects of long-term sulindac therapy on colonic polyposis
    • Rigau J, Pique JM, Rubio E, et al. Effects of long-term sulindac therapy on colonic polyposis. Ann Intern Med 1991;115:952-954.
    • (1991) Ann Intern Med , vol.115 , pp. 952-954
    • Rigau, J.1    Pique, J.M.2    Rubio, E.3
  • 64
    • 0030947525 scopus 로고    scopus 로고
    • Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2
    • Sheng H, Shao J, Kirkland SC, et al. Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. J Clin Invest 1997;99:2254-2259.
    • (1997) J Clin Invest , vol.99 , pp. 2254-2259
    • Sheng, H.1    Shao, J.2    Kirkland, S.C.3
  • 65
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995;83:493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 66
    • 0030952695 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
    • Tsujii M, Kawano S, DuBois RN. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci USA 1997;94:3336-3340.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3336-3340
    • Tsujii, M.1    Kawano, S.2    DuBois, R.N.3
  • 67
    • 0030606299 scopus 로고    scopus 로고
    • Suppression of intestinal polyposis in APC knockout mice by inhibition of cyclooxygenase 2 (COX-2)
    • Oshima M, Dinchuk JE, Kargman SL, et al. Suppression of intestinal polyposis in APC knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996;87:803-809.
    • (1996) Cell , vol.87 , pp. 803-809
    • Oshima, M.1    Dinchuk, J.E.2    Kargman, S.L.3
  • 68
    • 0030606276 scopus 로고    scopus 로고
    • Self-promotion? Intimate connections between APC and prostaglandin H synthase-2
    • Prescott SM, White RL. Self-promotion? Intimate connections between APC and prostaglandin H synthase-2. Cell 1996;87:783-786.
    • (1996) Cell , vol.87 , pp. 783-786
    • Prescott, S.M.1    White, R.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.