Biochemical, morphological, and functional analyses of a cyclic peptide, phospholipid, and DNA ternary complex used for gene delivery?

Journal of Liposome Research

Volumn 8, Issue 3, 1998, Pages 347-366

  Legendrea, Jean Yves ^a,c   Huang, Shi Kun ^b   Szoka Jr , Francis C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ALZA CORPORATION   (United States)

^c UPSA Laboratoires   (France)

Author keywords

Compaction; Electron microscopy; Gramicidin S; Phosphatidylethanolamine

Indexed keywords

CYCLOPEPTIDE; GRAMICIDIN S; MELITTIN; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; POLYLYSINE; POLYMYXIN B; TYROCIDINE;

ARTICLE; BASE PAIRING; COMPLEX FORMATION; DNA BINDING; DNA STRUCTURE; ELECTRON MICROSCOPY; GENE TARGETING; GENE THERAPY; GENETIC TRANSFECTION; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; SUCROSE GRADIENT;

EID: 0031657452     PISSN: 08982104     EISSN: None     Source Type: Journal    
DOI: 10.3109/08982109809035539     Document Type: Article

References (40)

1. Felgner, P.L. 1990. Particulate systems and polymers for in vitro and in vivo delivery of polynucleotides. Adv Drug Delivery Rev 5:163-187.
2. Behr, J.P. 1993. Synthetic gene-transfer vectors. Acc Chem Res 26:274-278.
3. Gao, X. and Huang, L. 1995. Cationic liposome mediated gene transfer. Gene Therap 2:710-722.
4. Nabel, G.J., Nabel, E.G., Yang, Z.Y., Fox, B.A., Plautz, G.E., Gao, X., Huang, L., Shu, S., Gordon, D. and Chang, A.E. 1993. Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity and lack of toxicity in humans. Proc Natl Acad Sci USA 90:11307-11311.
5. Felgner, P.L., Gadek, T., Holm, M., Roman, R., Chan, H.W., Wentz, M., Northrop, J.P., Ringold, G.M. and Danielsen, M. 1987. Lipofection: a highly efficient, lipidmediated DNA transfection procedure. Proc Natl Acad Sci USA 84:7413-7417.
6. Legendre, J.Y. and Szoka, F.C. 1992. Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes : comparison with cationic liposomes. Pharm Res 9:1235-1242.
7. Behr, J.P., Demeinex, B., Loeffler, J.P. and Perez-Mutul, J. 1989. Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA. Proc Natl Acad Sci USA 86:6982-6986.
8. Smyth-Templeton, N., Lasic, D.D., Frederik, P.M., Strey, H.H., Roberts, D.D. and Pavlakis, G.N. 1997. Improved DNA:liposome complexes for increased systemic delivery and gene expression. Nature Biotech 15:647-652.
9. Wagner, E., Plank, C., Zatloukal, K., Cotten, M. and Birnstiel, M.L. 1992. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes : toward a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci USA 89:7934-7938.
10. Wyman, T. , Nicol, F., Zelphati, O., Scaria, P.V., Plank, C. and Szoka, Jr., F.C. 1997. Design, synthesis and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry 36:3008-3017.
11. Legendre, J.Y., Trzeciak, A., Bohrmann, B., Deuschle, U., Kitas, E. and Supersaxo, A. 1997. Dioleoylmelittin as a novel serum-insensitive reagent for efficient transfection of mammalian cells. Bioconj Chem 8:57-63.
12. Haensler, J. and Szoka, Jr., F.C. 1993. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconj Chem 4:372-379.
13. Kabanov, A.V. and Kabanov, V.A. 1995. DNA complexes with polycations for the delivery of genetic material into cells. Bioconj Chem 6:7-20.
14. Legendre, J.Y. and Szoka, Jr., F.C. 1993. Cyclic amphipathic peptide-DNA complexes mediate high-efficiency transfection of adherent mammalian cells. Proc Natl Acad Sci USA 90:893-897.
15. Legendre, J.Y. and Supersaxo, A. 1995. Short-chain phospholipids enhance amphipathic peptide-mediated gene transfer. Biochem Biophys Res Commun 217:179-185.
16. De Wet, J.R., Wood, K.V., De Luca, M., Helinsky, D.R. and Subramani S. 1987. Firefly luciferase gene:structure and expression in mammalian cells. Mol Cell Biol 7:725-737.
17. Me Gregor, G.R. and Caskey, C.T. 1989. Construction of plasmids that express E. coli b-galactosidase in mammalian cell lines. Nuc Acids Res 17:2365-2370
18. Sambrook, J., Fritsch, E.F. and Maniatis T. 1989. Molecular cloning: a laboratory manual (Cold Spring Harbor Lab., Cold Spring Harbor, NY), 2nd ed.
19. Hunter, W.M. and Greenwood, F.C. 1962. Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature 194:495-496.
20. Brasier, A.R., Tate, J.E. and Habener J.F. 1989. Optimized use of firefly luciferase assay as a reporter gene in mammalian cell lines. Biotechniques 7:1116-1122.
21. Lim, K. and Chae, C.-B. 1989. A simple assay for DNA transfection by incubation of the cells in a culture dishes with substrates for beta-galactosidase. Biotechniques 7:576-579.
22. Mossmann, T.R. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55-63.
23. Parente, R.A., Nadasdi, L., Subbarao, N.K. and Szoka, Jr., F.C. 1990. Association of a pH-sensitive peptide with membrane vesicles : role of amino acid sequence. Biochemistry 29:8713-8719.
24. Wu, E.-S., Jacobson, K., Szoka, F. and Portis, Jr., A. 1978. Lateral diffusion of a hydrophobic peptide, N-4-nitrobenz-2-oxa-l,3-diazole gramicidin S in phospholipid multibilayers. Biochemistry 17:5543-5550.
25. Gershon, H., Ghirlando, R., Guttman, S.B. and Minsky, A. 1993. Mode of formation and structural features of DNA-cationic liposome complexes used for transfection. Biochemistry 32:7143-7151.
26. Lasic, D.D., Strey, H., Stuart, M.C., Podornik, R. and Frederik, P.M. 1997. The structure of DNA-liposome complexes. J. Am.Chem. Soc. 119:832-833.
27. Radler, J.O., Koltover, I., Salditt, T. and Safinya, C.R. 1997. Structure of DNA-cationic liposome complexes :DNA intercalation in multilamellar membranes in distinct interhelical packing regimes. Science 275:810-814.
28. Wagner, E., Gotten, M., Foisner, R. and Birnstiel, M. 1991. Transferrin-polycation-DNA complexes : the effect of polycations on the structure of the complex and DNA delivery to cells. Proc Natl Acad Sci USA 88:4255-4259.
29. Perales, J.C, Ferkol, T., Molas, M. and Hanson, R.W. 1994. An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes. Eur J Biochem 226:255-266.
30. Wagner, E., Zatloukal, K., Gotten, M., Kirlappos, H., Mechtler, K., Curiel, D.T. and Birnstiel, M.L. 1992. Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor mediated gene delivery and expression of transfected gene. Proc Natl Acad Sci USA 89:6099-6103.
31. Tang, M.X. and Szoka, Jr., F.C. 1997. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Therap 4:823-832.
32. Hansen, J., Pschorn, W. and Ristow, H. 1982. Functions of the peptide antibiotics tyrocidine and gramicidin: induction of conformational and structural changes of superhelical DNA. Eur J Biochem 126:279-284.
33. Krauss, E.M. and Chan, S.I. 1984. Complexation and phase transfer of nucleic acids by gramicidin S. Biochemistry 23:73-77.
34. Baeza, I., Gariglio, P., Rangel, L.M., Chavez, P., Cervantes, L., Arguello, C., Wong, C. and Montanez, C. 1987. Electron microscopy and biochemical properties of polyamine-compacted DNA. Biochemistry 26:6387-6392.
35. Tang, M.X. and Szoka, Jr., F.C. Characterization of polycation complexes with DNA, Chapter 9 in Self-Assembling Complexes for Gene Delivery: from Laboratory to Clinical Trial. A.V. Kabanov, P. Felgner and L.W. Seymour (eds.), pp. 169-196, J.Wiley & Sons, New York. 1998.
36. Prenner, E.J., Lewis, R.A.H.N., Neuman, K.C., Gruner, S.M., Kondejewski, L., Hodges, R.S. and McElhaney, R.N. 1997. Nonlamellar phases induced by the interaction of gramicidin S with lipid bilayers. A possible relationship to membrane-disrupting activity. Biochemistry 36:7906-7916.
37. Xu, Y. and Szoka, Jr., F.C. 1996. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 35:5616-5623.
38. Zelphati, O. and Szoka, Jr., F.C. 1996. Mechanism of oligonucleotide release from cationic liposomes. Proc Natl Acad Sci USA 93:11493-11498.
39. Hara, T., Kuwasawa, H., Aramaki, Y., Takada, S., Koike, K., Ishidate, K., Kato, H. and Tsuchiya, S. 1996. Effects of fusogenic and DNA-binding amphilic compounds on the receptor mediated gene transfer into hepatic cells by asialofetuin-labeled liposomes. Biochim Biophys Acta 1278:51-58.
40. Walker, S., Sofia, M.J., Kakarla, R., Kogan, N.A., et al. 1996. Cationic facial amphiles: a promising class of transfection agents. Proc Natl Acad Sci USA 93:1585-1590.