Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: An immunohistochemical study

Human Pathology

Volumn 28, Issue 5, 1997, Pages 613-622

  Kawano, Naomi ^a   Osawa, Hiroyuki ^a   Ito, Takaaki ^a   Nagashima, Yoji ^a   Hirahara, Fumiki ^a   Inayama, Yoshiaki ^a   Nakatani, Yukio ^a   Kimura, Seiko ^a   Kitajima, Hiroyuki ^a   Koshikawa, Naohiko ^a   Miyazaki, Kaoru ^a   Kitamura, Hitoshi ^a,b  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

immunohistochemistry; lung cancer; metalloproteinases; tissue inhibitor of metalloproteinases 2; trypsin(ogen)

Indexed keywords

GELATINASE A; MATRILYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TRYPSINOGEN;

ADULT; AGED; ARTICLE; CARCINOID; CELL DIFFERENTIATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG CARCINOMA; LUNG SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; PROTEIN EXPRESSION;

EID: 12644313220     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(97)90085-X     Document Type: Article

References (38)

1. Shimosato Y: Pulmonary neoplasm, in Sternberg SS (ed): Diagnostic Surgical Pathology (ed 2). New York, NY, Raven, 1994, pp 1045-1093
2. Colby T, Koss M, Trevis W: Tumor of the Lower Respiratory Tract: Atlas of Tumor Pathology (3rd series, fascicle 13). Washington, DC, Armed Forces Institute of Pathology, 1994
3. Cagle PT: Tumor of the lung (excluding lymphoid tumors), in Thurlbeck WH, Churg AM (eds): Pathology of the Lung (ed 2). New York, NY, Thieme, 1995, pp 437-551
4. Liotta LA: Tumor invasion and metastases: Role of the extracellular matrix. Cancer Res 46:1-7, 1986
5. Stetler-Stevenson WG, Aznavoorian S, Liotta LA: Tumor cell interaction with the extracellular matrix during invasion and metastasis. Ann Rev Cell Biol 9:541-573, 1993
6. Furcht L, Skubitz A, Fields G: Tumor cell invasion, matrix metalloproteinase, and the dogma. Lab Invest 70:781-783, 1994
7. Ohta T, Terada T, Nagakawa T, et al: Pancreatic trypsinogen and cathepsin B in human pancreatic carcinomas and associated metastatic lesions. Br J Cancer 69:152-156, 1994
8. Koivunen E, Saksela O, Itkonen O, et al: Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen. Int J Cancer 47:592-596, 1991
9. Koshikawa N, Yasumitsu H, Umeda M, et al: Multiple secretion of matrix serine proteinases by human gastric carcinoma cell lines. Cancer Res 52:5046-5053, 1992
10. Koshikawa N, Yasumitsu H, Nagashima Y, et al: Identification of one- and two-chain forms of trypsinogen 1 produced by a human gastric adenocarcinoma cell line. Biochem J 303:187-190, 1994
11. Terada T, Ohta T, Minato H, et al: Expression of pancreatic trypsinogen/trypsin and cathepsin B in human cholangiocarcinomas and hepatocellular carcinoma. HUM PATHOL 26:746-752, 1995
12. Hirahara F, Miyagi Y, Miyagi E, et al: Trypsinogen expression in human ovarian carcinomas. Int J Cancer 63:176-181, 1995
13. Urbanski SJ, Edwards DR, Maitland A, et al: Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas. Br J Cancer 66:1188-1194, 1992
14. Ohori NP, Yousem SA, Griffin J, et al: Comparison of extracellular matrix antigens in subtypes of bronchioloalveolar carcinoma and conventional pulmonary adenocarcinoma: An immunohistochemical study. Am J Surg Pathol 16:675-686, 1992
15. Soini Y, Pääkö P, Helena A: Genes of laminin B1 chain, α1- (IV) chain of type IV collagen, and 72-kd type IV collagenase are mainly expressed by the stromal cells of lung carcinomas. Am J Pathol 142:1622-1630, 1993
16. Nakagawa H, Yagihashi S: Expression of type IV collagen and its degrading enzymes in squamous cell carcinoma of lung. Jpn J Cancer Res 85:934-938, 1994
17. Nomura H, Sato H, Seiki M, et al: Expression of membranetype matrix metalloproteinase in human gastric carcinomas. Cancer Res 55:3263-3266, 1995
18. Monteagudo C, Merino MJ, San-Juan J, et al: Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue. AmJ Pathol 136:583-592, 1990
19. Levy AT, Cioce V, Sobel ME, et al: Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma. Cancer Res 51:439-444, 1991
20. Poulsom R, Pignatelli M, Stetler-Stevenson WG, et al: Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia. Am J Pathol 141:389-396, 1992
21. Campo E, Merino MJ, Tavassoli FA, et al: Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumors of the ovary. Am J Surg Pathol 16:100-107, 1992
22. Campo E, Merino MJ, Liotta LA, et al: Distribution of the 72-kd type IV collagenase in nonneoplastic and neoplastic thyroid tissue. HUM PATHOL 23:1395-1401, 1992
23. Garbisa S, Scagliotti G, Masiero L, et al: Correlation of serum metalloproteinase levels with lung cancer metastasis and response to therapy. Cancer Res 52:4548-4549, 1992
24. Brown PD, Bloxidge RE, Stuart NSA, et al: Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma. J Natl Cancer Inst 85:574-578, 1993
25. Umenishi F, Umeda M, Miyazaki K: Efficient purification of TIMP-2 from culture medium conditioned by human hepatoma cell line, and its inhibitory effects on metalloproteinases and in vitro tumor invasion. J Biochem 110:189-195, 1991
26. Albini A, Melchiori A, Santi L, et al: Tumor cell invasion inhibited by TIMP-2. J Natl Cancer Inst 83:775-779, 1991
27. DeClerck YA, Yean T-D, Chan D, et al: Inhibition of tumor invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor. Cancer Res 51:2151-2157, 1991
28. DeClerck YA, Perez N, Shimada H, et al: Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases. Cancer Res 52:701-708, 1992
29. Testa JE: Loss of the metastatic phenotype by a human epidermoid carcinoma cell line, HEp-3, is accompanied by increased expression of tissue inhibitor of metalloproteinase 2. Cancer Res 52:5597-5603, 1992
30. Miyagi E, Yasumitsu H, Hirahara F, et al: Characterization of matrix-degrading proteinases and their inhibitors secreted by human gynecological carcinoma cells. Jpn J Cancer Res 86:568-576, 1995
31. Miyazaki K, Hattori Y, Umenishi F, et al: Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin (pump-1), secreted from human rectal carcinoma cell line. Cancer Res 50:7758-7764, 1990
32. Powell WC, Knox JD, Navre M, et al: Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice. Cancer Res 53:417-422, 1993
33. Witty JP, McDonnell S, Newell KJ, et al: Modulation of matrilysin levels in colon carcinoma cell lines affects tumorigenicity in vivo. Cancer Res 54:4805-4812, 1994
34. McDonnell S, Navre M, Robert JC, et al: Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. Mol Carcinogenesis 4:527-533, 1991
35. Newell KJ, WittyJP, Rodgers WH, et al: Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis. Mol Carcinogenesis 10:199-206, 1994
36. Muller D, Breathnach R, Engelmann A, et al: Expression of collagenase-related metalloproteinase gene in human lung or head and neck tumours. Int J Cancer 48:550-556, 1991
37. Saarialho-Kere UK, Crouch EC, Parks WC: Matrix metalloproteinase matrilysin is constitutively expressed in adult human exocrine epithelium. J Invest Dermatol 105:190-196, 1995
38. Busiek DF, Ross FP, McDonnell S, et al: The matrix metalloprotease matrilysin (PUMP) is expressed in developing human mononuclear phagocytes. J Biol Chem 267:9087-9092, 1992