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Volumn 77, Issue 1, 1998, Pages 87-95

Milacemide, a glycine pro-drug, inhibits strychnine-allodynia without affecting normal nociception in the rat

Author keywords

Allodynia; Milacemide; Monoamine oxidase; Nociception; Rat; Spinal; Strychnine

Indexed keywords

ANTICONVULSIVE AGENT; CLORGYLINE; GLYCINE RECEPTOR; MILACEMIDE; MONOAMINE OXIDASE INHIBITOR; SELEGILINE; STRYCHNINE;

EID: 0031656553     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(98)00086-4     Document Type: Article
Times cited : (12)

References (29)
  • 1
    • 0022246192 scopus 로고
    • Hyperalgesia induced by altered glycinergic activity at the spinal cord
    • Beyer C., Roberts L.A., Komisruk B.R. Hyperalgesia induced by altered glycinergic activity at the spinal cord. Life Sci. 37:1985;875-882.
    • (1985) Life Sci. , vol.37 , pp. 875-882
    • Beyer, C.1    Roberts, L.A.2    Komisruk, B.R.3
  • 2
    • 0023872193 scopus 로고
    • Prevention of the convulsant and hyperalgesic action of strychnine by intrathecal glycine and related amino acids
    • Beyer C., Banas C., Gomora P., Komisruk B.R. Prevention of the convulsant and hyperalgesic action of strychnine by intrathecal glycine and related amino acids. Pharmacol. Biochem. Behav. 29:1988;73-78.
    • (1988) Pharmacol. Biochem. Behav. , vol.29 , pp. 73-78
    • Beyer, C.1    Banas, C.2    Gomora, P.3    Komisruk, B.R.4
  • 3
    • 0023924048 scopus 로고
    • Myelinated afferents signal hyperalgesia associated with nerve injury
    • Campbell N.J., Raja N.S., Meyer A.R., Mckinnon E.S. Myelinated afferents signal hyperalgesia associated with nerve injury. Pain. 32:1988;89-94.
    • (1988) Pain , vol.32 , pp. 89-94
    • Campbell, N.J.1    Raja, N.S.2    Meyer, A.R.3    Mckinnon, E.S.4
  • 4
    • 84878803927 scopus 로고
    • Conversion of orally administered 2-n-pentylaminoacetamide into glycinamide and glycine in the rat brain
    • Christophe, J., Kutzner, J.R., Nguyen-Bui, N.D., Damien, C., Chatelain, P. and Gillet, L., Conversion of orally administered 2-n-pentylaminoacetamide into glycinamide and glycine in the rat brain, Life Sci., 33 (1983) 533-541.
    • (1983) Life Sci. , vol.33 , pp. 533-541
    • Christophe, J.1    Kutzner, J.R.2    Nguyen-Bui, N.D.3    Damien, C.4    Chatelain, P.5    Gillet, L.6
  • 5
    • 0014389928 scopus 로고
    • A pharmacological study of the depression of spinal neurons by glycine and related amino acids
    • Curtis D.R., Hösli L., Johnston G.A.R. A pharmacological study of the depression of spinal neurons by glycine and related amino acids. Exp. Brain Res. 6:1968;1-18.
    • (1968) Exp. Brain Res. , vol.6 , pp. 1-18
    • Curtis, D.R.1    Hösli, L.2    Johnston, G.A.R.3
  • 6
    • 0023948924 scopus 로고
    • Formation of the neurotransmitter glycine from the anticonvulsant milacemide is mediated by brain monoamine oxidase B
    • de Varebeke, P.J., Cavalier, R., David-Remacle, M. and Youdim, M.B.H., Formation of the neurotransmitter glycine from the anticonvulsant milacemide is mediated by brain monoamine oxidase B, J. Neurochem., 50 (1988) 12011-1016.
    • (1988) J. Neurochem. , vol.50 , pp. 12011-21016
    • De Varebeke, P.J.1    Cavalier, R.2    David-Remacle, M.3    Youdim, M.B.H.4
  • 8
    • 0016750653 scopus 로고
    • The pharmacology of inhibition of the dorsal horn neurons by impulses in myelinated cutaneous afferents in the cat
    • Game C.J.A., Lodge D. The pharmacology of inhibition of the dorsal horn neurons by impulses in myelinated cutaneous afferents in the cat. Exp. Brain Res. 23:1975;75-84.
    • (1975) Exp. Brain Res. , vol.23 , pp. 75-84
    • Game, C.J.A.1    Lodge, D.2
  • 10
    • 0030863922 scopus 로고    scopus 로고
    • Comparable dose-dependent inhibition of AP-7 sensitive strychnine-allodynia and normal nociception by intravenous mexiletine in the rat
    • Khandwala H., Hodge E., Loomis C.W. Comparable dose-dependent inhibition of AP-7 sensitive strychnine-allodynia and normal nociception by intravenous mexiletine in the rat. Pain. 72:1997;299-308.
    • (1997) Pain , vol.72 , pp. 299-308
    • Khandwala, H.1    Hodge, E.2    Loomis, C.W.3
  • 11
    • 0029996525 scopus 로고    scopus 로고
    • Innocuous hair deflection evokes a nociceptive-like activation of catechol oxidation in the rat locus coeruleus following intrathecal strychnine: A biochemical index of allodynia using in vivo voltammetry
    • Milne B., Duggan S., Jhamandas K., Loomis C.W. Innocuous hair deflection evokes a nociceptive-like activation of catechol oxidation in the rat locus coeruleus following intrathecal strychnine: a biochemical index of allodynia using in vivo voltammetry. Brain Res. 718:1996;198-202.
    • (1996) Brain Res. , vol.718 , pp. 198-202
    • Milne, B.1    Duggan, S.2    Jhamandas, K.3    Loomis, C.W.4
  • 13
    • 0029993392 scopus 로고    scopus 로고
    • Involvement of glutamate receptors in strychnine- And bicuculline-induced allodynia in conscious mice
    • Onaka M., Minami T., Nishihara I., Ito S. Involvement of glutamate receptors in strychnine- and bicuculline-induced allodynia in conscious mice. Anesthesiology. 84:1996;1215-1222.
    • (1996) Anesthesiology , vol.84 , pp. 1215-1222
    • Onaka, M.1    Minami, T.2    Nishihara, I.3    Ito, S.4
  • 14
    • 0028814348 scopus 로고
    • Comparison of the action of glycine and related amino acids on the isolated third order neurons from the tiger salamander retina
    • Pan Z.H., Slaughter M.M. Comparison of the action of glycine and related amino acids on the isolated third order neurons from the tiger salamander retina. Neuroscience. 64:1995;153-164.
    • (1995) Neuroscience , vol.64 , pp. 153-164
    • Pan, Z.H.1    Slaughter, M.M.2
  • 17
    • 0345663788 scopus 로고    scopus 로고
    • Hair deflection evokes localized nociceptive-like activation of glycogen phoshorylase activity in the cortex of intrathecal strychnine-treated rats
    • New Orleans
    • Sawler, S., Khandwala, H., Harley, C. and Loomis, C.W., Hair deflection evokes localized nociceptive-like activation of glycogen phoshorylase activity in the cortex of intrathecal strychnine-treated rats, Society for Neuroscience, New Orleans, 1997.
    • (1997) Society for Neuroscience
    • Sawler, S.1    Khandwala, H.2    Harley, C.3    Loomis, C.W.4
  • 18
    • 0027497638 scopus 로고
    • Milacemide effects on the temporal inter-relationship of amino acids and monoamine metabolites in rat cerebrospinal fluid
    • Semba J., Patsalos P.N. Milacemide effects on the temporal inter-relationship of amino acids and monoamine metabolites in rat cerebrospinal fluid. Eur. J. Pharmacol. 230:1993;321-326.
    • (1993) Eur. J. Pharmacol. , vol.230 , pp. 321-326
    • Semba, J.1    Patsalos, P.N.2
  • 19
    • 0027483520 scopus 로고
    • Antiepileptic drug pharmacokinetics and neuropharmacokinetics in individual rats by repetitive withdrawal of blood and cerebrospinal fluid: Milacemide
    • Semba J., Curzon G., Patsalos P.N. Antiepileptic drug pharmacokinetics and neuropharmacokinetics in individual rats by repetitive withdrawal of blood and cerebrospinal fluid: milacemide. Br. J. Pharmacol. 108(4):1993;1117-1124.
    • (1993) Br. J. Pharmacol. , vol.108 , Issue.4 , pp. 1117-1124
    • Semba, J.1    Curzon, G.2    Patsalos, P.N.3
  • 20
    • 0027979339 scopus 로고
    • Morphine insensitive allodynia is produced by intrathecal strychnine in the lightly anesthetized rat
    • Sherman S.E., Loomis C.W. Morphine insensitive allodynia is produced by intrathecal strychnine in the lightly anesthetized rat. Pain. 56:1994;17-29.
    • (1994) Pain , vol.56 , pp. 17-29
    • Sherman, S.E.1    Loomis, C.W.2
  • 21
    • 0029552808 scopus 로고
    • Strychnine-dependent allodynia in the urethane-anesthetized rat is segmentally distributed and prevented by intrathecal glycine and betaine
    • Sherman S.E., Loomis C.W. Strychnine-dependent allodynia in the urethane-anesthetized rat is segmentally distributed and prevented by intrathecal glycine and betaine. Can. J. Physiol. Pharmacol. 73:1995;1698-1705.
    • (1995) Can. J. Physiol. Pharmacol. , vol.73 , pp. 1698-1705
    • Sherman, S.E.1    Loomis, C.W.2
  • 22
    • 0030220221 scopus 로고    scopus 로고
    • Strychnine-sensitive modulation is selective for non-noxious somatosensory input in the spinal cord
    • Sherman S.E., Loomis C.W. Strychnine-sensitive modulation is selective for non-noxious somatosensory input in the spinal cord. Pain. 66:1996;321-330.
    • (1996) Pain , vol.66 , pp. 321-330
    • Sherman, S.E.1    Loomis, C.W.2
  • 23
    • 0030792597 scopus 로고    scopus 로고
    • Spinal strychnine alters response properties of nociceptive-specific neurons in rat medial thalamus
    • Sherman S.E., Luo L., Dostrovsky D.O. Spinal strychnine alters response properties of nociceptive-specific neurons in rat medial thalamus. J. Neurophysiol. 78:1997;628-637.
    • (1997) J. Neurophysiol. , vol.78 , pp. 628-637
    • Sherman, S.E.1    Luo, L.2    Dostrovsky, D.O.3
  • 25
    • 0025609852 scopus 로고
    • An electron microscope study of glycine-like immunoreactivity in lamina I-III of the spinal dorsal horn of the rat
    • Todd A.J. An electron microscope study of glycine-like immunoreactivity in lamina I-III of the spinal dorsal horn of the rat. Neuroscience. 39:1990;387-394.
    • (1990) Neuroscience , vol.39 , pp. 387-394
    • Todd, A.J.1
  • 26
    • 0025368953 scopus 로고
    • Light microscopic study of the coexistence of GABA-like and glycine-like immunoreactivities in the spinal cord of the rat
    • Todd A.J., Sullivan A.C. Light microscopic study of the coexistence of GABA-like and glycine-like immunoreactivities in the spinal cord of the rat. J. Comp. Neurol. 296:1990;496-505.
    • (1990) J. Comp. Neurol. , vol.296 , pp. 496-505
    • Todd, A.J.1    Sullivan, A.C.2
  • 28
    • 0024602581 scopus 로고
    • Behavioral and autonomic correlates of tactile evoked allodynia produced by spinal glycine inhibition: Effects of modulatory receptor systems and excitatory amino acid antagonists
    • Yaksh T.L. Behavioral and autonomic correlates of tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists. Pain. 37:1989;111-123.
    • (1989) Pain , vol.37 , pp. 111-123
    • Yaksh, T.L.1
  • 29
    • 0023923318 scopus 로고
    • The glycine pro-drug, milacemide, increases the seizure threshold due to hyperbaric oxygen: Prevention by L-deprenyl
    • Youdim M.B.H., Kerem D., Duvdevani Y. The glycine pro-drug, milacemide, increases the seizure threshold due to hyperbaric oxygen: prevention by L-deprenyl. Eur. J. Pharmacol. 150:1988;381-384.
    • (1988) Eur. J. Pharmacol. , vol.150 , pp. 381-384
    • Youdim, M.B.H.1    Kerem, D.2    Duvdevani, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.