Innocuous hair deflection evokes a nociceptive-like activation of catechol oxidation in the rat locus coeruleus following intrathecal strychnine: A biochemical index of allodynia using in vivo voltammetry

Brain Research

Volumn 718, Issue 1-2, 1996, Pages 198-202

  Milne, Brian ^a   Duggan, Scott ^a   Jhamandas, Khem ^a   Loomis, Christopher ^b  

^a QUEEN S UNIVERSITY   (Canada)

^b MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Allodynia; Excitatory amino acid; Glycine; Locus ceruleus; Spinal cord; Strychnine; Voltammetry

Indexed keywords

CATECHOLAMINE; DIZOCILPINE; GLYCINE RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; STRYCHNINE;

ALLODYNIA; ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; INTRATHECAL DRUG ADMINISTRATION; LOCUS CERULEUS; MALE; NONHUMAN; POTENTIOMETRY; PRIORITY JOURNAL; RAT; SPINAL CORD;

ANIMALS; BIOLOGICAL MARKERS; BIOTRANSFORMATION; BLOOD PRESSURE; CATECHOLS; ELECTRODES, IMPLANTED; GLYCINE AGENTS; HAIR; INJECTIONS, SPINAL; LOCUS COERULEUS; MALE; NOCICEPTORS; OXIDATION-REDUCTION; PAIN; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; STRYCHNINE;

EID: 0029996525     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00072-8     Document Type: Article

References (32)

1. Adams, R.N., In vivo electrochemical measurements in the CNS, Prog. Neurobiol., 35 (1990) 297-311.
2. Beyer, C., Roberts, L.A. and Komisaruk, B.R., Hyperalgesia induced by altered glycinergic activity at the spinal cord, Life Sci., 37 (1985) 875-882.
3. Buda, M. and Gonon, F.G., Study of brain noradrenergic neurons by use of in vivo voltammetry. In J.B. Justice (Ed.), Voltammetry in the Neurosciences, Humana Press, Clifton, NJ, 1987, pp. 239-272.
4. Curet, O., Denis, T. and Scatton, B., The formation of deaminated metabolites of dopamine in the locus coeruleus depends upon noradrenergic activity, Brain Res., 335 (1985) 297-301.
5. Dahlstrom, A. and Fuxe, K., Evidence for the existence of monoamine - containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brain stem neurons, Acta Physiol. Scand., 62 (1964) 1-55.
6. Dickenson, A.H. and Aydar, E., Anatagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat, Neurosci. Lett., 121 (1991) 263-266.
7. Duggan, S., Hong, M., Milne, B. and Jhamandas, K., The role of excitatory amino acids in the expression of precipitated acute and chronic clonidine withdrawal: an in vivo voltammetric study in the rat locus coeruleus, Brain Res., 665 (1994) 253-261.
8. Gonon, F., Buda, M., Cespuglio, R., Jouvet, M. and Pujol, J.F., In vivo electrochemical detection of catechols in the neostriatum of anaesthetized rats: dopamine or DOPAC? Nature, 286 (1980) 902-904.
9. Hong, M., Milne, B., Loomis, C.W. and Jhamandas, K., In vivo catechol activity in the rat locus coeruleus following different nociceptive stimuli and naloxone, Can. J. Physiol. Pharmacol., 70 (1992) 1082-1089.
10. Jessell, T.M., Yoshioka, K. and Jahr, C.E., Amino acid receptor-mediated transmission at primary afferent synapses in rat spinal cord, J. Exp. Biol., 124 (1986) 239-258.
11. Korf, J., Bunney, B.S. and Aghajanian, G.K., Noradrenergic neurons: morphine inhibition of spontaneous activity, Eur. J. Pharmacol., 25 (1974) 165-169.
12. Lambás-Senas, L., Gillon, J.Y., Bouilloux, J.P., Seecia, M., Buda, M. and Renaud, B., In vivo monitoring of catecholaminergic metabolism in the C1 region of rat medulla oblongata: a comparative study by voltammetry and intracerebral microdialysis, J. Neurochem., 54 (1990) 2042-2049.
13. Marsden, C.A., Joseph, M.H., Kruk, Z.C., Maidment, N.T., O'Neill, R.D., Schenk, J.O. and Stamford, J.A., In vivo voltammetry-present electrodes and methods, Neuroscience, 25 (1988) 389-400.
14. Merskey, H., Classification of chronic pain. Part II, Pain, Suppl 3. (1986) S215-221.
15. Milne, B., Quintin, L. and Gillon, J.Y., Changes in catecholamine metabolism in the rostral ventrolateral medulla following halothane and nitroprusside-induced hypotension: an in vivo electrochemical study, Brain Res., 518 (1990) 143-148.
16. Morris, R., Responses of spinal dorsal horn neurones evoked by myelinated primary afferent stimulation are blocked by excitatory amino acid antagonists acting at kainate/quisqualate receptors, Neurosci. Lett., 105 (1989) 79-85.
17. Ortemann, C., Robert, F., Renaud, B. and Lambás-Senas, L., In vivo microdialysis study of the extracellular 3,4-dihydroxyphenylacetic acid in the rat locus coeruleus: topographical and pharmacological aspects, J. Neurochem., 61 (1993) 594-601.
18. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1982.
19. Ponchon, J.L., Cespuglio, R., Gonon, F., Jouvet, M. and Pujol, F., Normal pulse polarography with carbon fiber electrodes for in vitro and in vivo determination of catecholamines, Anal. Chem., 51 (1979) 1483-1486.
20. Quintin, L., Hilaire, G. and Pujol, J.F., Variations in dopac concentration are correlated to single cell firing changes in the rat locus coeruleus, Neuroscience, 18 (1986) 889-899.
21. Salt, T.E. and Hill, R.G., Neurotransmitter candidates of somatosensory primary afferent fibres, Neuroscience, 10 (1983) 1083-1103.
22. Suaud-Chagny, M.F., Cespuglio, R., Rivot, J.P., Buda, M. and Gonon, F., High sensitivity measurement of brain catechols and indoles in vivo using electrochemically treated carbon-fiber electrodes, J. Neurosci. Meth., 48 (1993) 241-250.
23. Sherman, S.E. and Loomis, C.W., Morphine insensitive allodynia is produced by intrathecal strychnine in the lightly anesthetized rat, Pain, 56 (1994) 17-29.
24. Sherman, S.E. and Loomis, C.W., Pharmacology of intrathecal strychnine-dependent allodynia in the anesthetized rat: role of glycine and substance P. Proceeding of the XIIth International Congress of Pharmacology, Can. J. Physiol. Pharmacol., 72 (1994) 13-45 (and submitted for publication, Pain).
25. Sherman, S.E. and Loomis, C.W., Morphine and excitatory amino acid antagonists distinguish allodynia from other pain states. Soc. Neurosci. Abst., 19 (1993) 396, 13 (and submitted for publication, Can. J. Physiol. Pharmacol.).
26. A, serotonin, or opiate receptors, augments responsiveness of locus coeruleus neurons to excitatory stimulation, Neuropharmacology, 28 (1988) 651-660.
27. Valentino, R.J. and Wehby, R.G., Morphine effects on locus coeruleus neurons are dependent on the state of arousal and availability of external stimuli: studies in anesthetized and unanesthetized rats, J. Pharmacol. Exp. Ther., 244 (1988) 1178-1186.
28. Wightman, R.M., Strope, E., Plotsky, P.M. and Adams, R.N., Monitoring of transmitter metabolites by voltammetry in cerebrospinal fluid following neural pathway stimulation, Nature, 262 (1976) 145-146.
29. Wightman, R.M., Microvoltammetric electrodes, Anal. Chem., 53 (1981) 1125-1130.
30. Wong, E.H.F., Kemp, J.A., Priestly, T., Knight, A.R., Woodruff, G.N. and Iversen, L.L., The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist, Proc. Natl. Acad. Sci. USA, 83 (1986) 7104-7108.
31. Yaksh, T.L. and Rudy, T.A., Chronic catheterization of the spinal subarachnoid space, Physiol. Behav., 17 (1976) 1031-1036.
32. Yaksh, T.L., Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists, Pain, 37 (1989) 111-123.