Direct dopamine D2-receptor-mediated modulation of arachidonic acid release in transfected CHO cells without the concomitant administration of a Ca2+-mobilizing agent

British Journal of Pharmacology

Volumn 124, Issue 8, 1998, Pages 1651-1658

  Nilsson, Christer L ^a   Hellstrand, Monika ^a   Ekman, Agneta ^a   Eriksson, Elias ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

( ) 3 PPP; Arachidonic acid; CHO cells; Dopamine; Dopamine D2 receptors; Haloperidol; Inverse agonism

Indexed keywords

3,4,5 TRIMETHOXYBENZOIC ACID 8 (DIETHYLAMINO)OCTYL ESTER; ADENOSINE TRIPHOSPHATE; ARACHIDONIC ACID; CALCIMYCIN; DOPAMINE; DOPAMINE 2 RECEPTOR; MEPACRINE; PERTUSSIS TOXIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTIRELIN; RACLOPRIDE; SULPIRIDE; THROMBIN; BORDETELLA VIRULENCE FACTOR; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; DRUG DERIVATIVE; GALLIC ACID; N-N-PROPYL-3-(3-HYDROXYPHENYL)PIPERIDINE; PIPERIDINE DERIVATIVE; PRECLAMOL; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CALCIUM MOBILIZATION; CHO CELL; CONTROLLED STUDY; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; HAMSTER; METABOLISM; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; ARACHIDONIC ACID; CALCIUM; CALCIUM CHANNEL BLOCKERS; CHO CELLS; CRICETINAE; CYCLOOXYGENASE INHIBITORS; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; GALLIC ACID; PERTUSSIS TOXIN; PIPERIDINES; RECEPTORS, DOPAMINE D2; TRANSFECTION; VIRULENCE FACTORS, BORDETELLA;

EID: 0031595478     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702025     Document Type: Article

References (56)

1. ACTON, R.T., BARSTAD, P.A. & ZWERNER, R.K. (1979). General cell culture techniques. In Methods Enzymol. Vol. LVIII: Cell Culture, eds Jakoby, W.B. & Pastan, I.H. pp 211-221. New York: Academic Press.
2. 2 via GTP-binding proteins: arachidonic acid and its metabolites as second messengers. Trends Neurosci., 11, 117-123.
3. 2 dopamine receptors by receptor desensitization and adenylyl cyclase sensitization. Mol. Pharmacol., 39, 55-63.
4. 1B-like receptor function via arachidonic acid metabolism. Mol. Pharmacol., 50, 1017-1023.
5. BOCKAERT, J., BRAND, C. & JOURNOT, L. (1997). Do recombinant receptor assays provide affinity and potency estimates? Ann. N. Y. Acad. Sci., 812, 55-70.
6. CHIDIAC, P., GREEN, M.A., PAWAGI, A.B. & WELLS, J.W. (1997). Cardiac muscarinic receptors. Cooperativity as the basis for multiple states of affinity. Biochemistry, 36, 7361-7379.
7. 2 dopamine receptor in rat and bovine caudate nucleus. Nature, 343, 266-269.
8. 2 dopamine receptors. Mol. Pharmacol., 45, 51-60.
9. CHIU, T.T., YUNG, L.Y. & WONG, Y.H. (1996). Inverse agonistic effect of ICI-174,864 on the cloned δ5-opioid receptor: role of G-protein and adenylyl cyclase activation. Mol. Pharmacol., 50, 1651-1657.
10. 2 receptor-dependent potentiation of arachidonic acid release. J. Neurochem., 59, 379-382.
11. 2 receptor by protein kinase C. J. Neurosci., 13, 4846-4853.
12. DI MARZO, V. (1995). Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions. Prostagland. Leukotri. Ess. Fatty Acid, 53, 239-254.
13. i that amplifies ATP-mediated arachidonic acid release. Proc. Natl. Acad. Sci. U.S.A., 88, 6477-6480.
14. 2+ channels in hippocampal neurones. Eur. J. Pharmacol., 267, 249-252.
15. 2 and the hypofrontality hypothesis of schizophrenia. Prostagland. Leukotri. Ess. Fat. Acid, 55, 109-113.
16. 2 dopamine receptors inhibits protein kinase C activity in striatal synaptoneurosomes. J. Neurochem., 63, 169-176.
17. 2 enzymes: regulation and inhibition. Trends Pharmacol. Sci., 14, 92-98.
18. 2+ antagonist in cultured mouse cortical neurones. NeuroReport, 5, 605-608.
19. 3 receptor. J. Neural Transm., 103, 1163-1175.
20. 2. Science, 249, 662-666.
21. 2-adrenoceptor on ligand affinity in transgenic mice. Mol. Pharmacol., 52, 187-194.
22. 2-dopamine receptor heterologously expressed in CHO cells. Br. J. Pharmacol., 117 (suppl), 282P.
23. 2 dopamine receptor heterologously expressed in CHO cells. Br. J. Pharmacol., 119 (suppl), 268P.
24. 2 dopamine receptors. Br. J. Pharmacol., 121, 731-736.
25. 2B subtypes in a heterologous cell line. Mol. Endocrinol., 6, 920-926.
26. HORROBIN, D.F. (1996). Schizophrenia as a membrane lipid disorder which is expressed throughout the body. Prostagland. Leukotri. Ess. Fat. Acid, 55, 3-7.
27. JACKOWSKI, S. (1996). Cell cycle regulation of membrane phospholipid metabolism. J. Biol. Chem., 271, 20219-20222.
28. 2 and of adenylate cyclase in transfected Chinese hamster ovary cells is mediated by different mechanisms. Mol. Pharmacol., 39, 239-245.
29. 2 dopamine receptors mediate the potentiation of arachidonic acid release in Chinese hamster ovary cells. Mol. Pharmacol., 39, 364-369.
30. KATSUKI, H. & OKUDA, S. (1995). Arachidonic acid as a neurotoxic and neurotrophic substance. Progr. Neurobiol., 46, 607-636.
31. KENAKIN, T. (1996). The classification of seven transmembrane receptors in recombinant expression systems. Pharmacol. Rev., 48, 413-463.
32. KOIZUMI, S., IKEDA, M., NAKAZAWA, K., INOUE, K., ITO, K. & INOUE, K. (1995). Inhibition by haloperidol of adenosine 5′-triphosphate-evoked responses in rat pheochromocytoma cells. Biochem. Biophys. Res. Commun., 210, 624-630.
33. 1 dopamine receptor. Mol. Pharmacol., 52, 1137-1149.
34. 2 guanine nucleotide-binding protein-coupled receptor: Utilization of receptor state binding affinities. Mol. Pharmacol., 42, 432-438.
35. 2 dopamine receptor stimulation of mitogenesis in transfected Chinese hamster ovary cells: Relationship to dopamine stimulation of tyrosine phosphorylations. J. Pharmacol. Exp. Ther., 267, 1573-1581.
36. 4 dopamine receptors determined in transfected cell lines. Clin. Neuropharmacol., 18 (suppl 1), S25-S33.
37. LEFF, P., SCARAMELLI, C., LAW, C. & McKECHNIE, K. (1997). A three-state receptor model of agonist action. Trends Pharmacol. Sci., 18, 4355-4362.
38. 2 is coupled to hormonally regulated release of arachidonic acid. Proc. Natl. Acad. Sci. U.S.A., 89, 6147-6151.
39. MALMBERG, Å., BACKLUND HÖÖK, B., JOHANSSON, A.M. & HACKSELL, U. (1996). Novel (R)-2-amino-5-fluorotetralins: dopaminergic antagonists and inverse agonists. J. Med. Chem., 39, 4421-4429.
40. MALMBERG, Å., NORDVALL, G., MIKAELS, Ä., JOHANSSON, A.M., HACKSELL, U. & MOHELL, N. (1997). Molecular pharmacology of human cloned dopamine receptor subtypes. Pharmacol. Toxicol., 81 (suppl S1), 9.
41. MULLANEY, I., CARR, C. & MILLIGAN, G. (1996). Analysis of inverse agonism at the δ opioid receptor after expression in Rat 1 fibroblasts. Biochem. J., 315, 227-234.
42. 2 in Chinese hamster ovary cells. Eur. J. Biochem., 230, 164-169.
43. MURUYAMA, T., ODA, H., WATANABE, A. & NOMURA, Y. (1995). ATP receptor-mediated increase of a Ca ionophore-stimulated arachidonic acid release from PC 12 pheochromocytoma cells. Jpn. J. Pharmacol., 69, 43-51.
44. 2 receptor is antagonized by R(-)-n-propylnorapo-morphine, raclopride, and phenoxybenzamine. Neuropsychopharmacol., 15, 53-61.
45. 2 receptors? J. Neural Transm. [Gen. Sect.]. 92, 213-220.
46. PARDO, P., CAMPILLO, M. & GIRALDO, M. (1997). The effect of the molecular mechanism of G-protein-coupled receptor activation on the process of signal transduction. Eur. J. Pharmacol., 335, 73-87.
47. 1D-adrenergic receptors to multiple signaling pathways is both G protein and cell type specific. Mol. Pharmacol., 44, 784-795.
48. 2. J. Lipid Mediat., 6, 433-443.
49. 2 receptor synergism. Nature, 353, 164-167.
50. 3 dopamine receptor. Neurosci. Lett., 226, 91-94.
51. 2 activity is selectively decreased in the striatum of chronic cocaine users. J. Neurochem., 67, 2620-2623.
52. 2-dopamine receptors on arachidonic acid release and cyclic AMP production in striatal neurons. J. Neurochem., 62, 944-949.
53. 2+ release from rat brain microsomes. Biol. Psychiatry, 40, 497-502.
54. SHEA, L. & LINDERMAN, J.J. (1997). Mechanistic model of G-protein signal transduction. Determinants of efficacy and effect of precoupled receptors. Biochem. Pharmacol., 53, 519-539.
55. 2. J. Neurochem., 64, 2765-2772.
56. 2 muscarinic acetylcholine receptor-effector coupling in Chinese hamster ovary cells. J. Biol. Chem., 270, 15485-15493.