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Volumn 70, Issue 3, 1998, Pages 1182-1188

α2-macroglobulin attenuates β-amyloid peptide 1-40 fibril formation and associated neurotoxicity of cultured fetal rat cortical neurons

Author keywords

Alzheimer's disease; Neurotoxicity; 2 Macroglobulin; Amyloid peptides

Indexed keywords

ALPHA 2 MACROGLOBULIN; AMYLOID BETA PROTEIN; CHYMOTRYPSIN INHIBITOR; ALPHA 1 ANTICHYMOTRYPSIN; AMYLOID BETA PROTEIN[1-40]; NEUROTOXIN; PEPTIDE FRAGMENT; PROTEINASE; SERINE PROTEINASE INHIBITOR;

EID: 0031594756     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70031182.x     Document Type: Article
Times cited : (105)

References (41)
  • 1
    • 0026682931 scopus 로고
    • Solution conformation and aggregational properties of synthetic amyloid β-peptides of Alzheimer's disease
    • Barrow C. J., Yasuda A., Kenny P. T. M., and Zagorski M. G. (1992) Solution conformation and aggregational properties of synthetic amyloid β-peptides of Alzheimer's disease. J. Mol. Biol. 225, 1075-1093.
    • (1992) J. Mol. Biol. , vol.225 , pp. 1075-1093
    • Barrow, C.J.1    Yasuda, A.2    Kenny, P.T.M.3    Zagorski, M.G.4
  • 4
    • 0027076834 scopus 로고
    • 2-Macroglobulin, a multifunctional binding protein with targeting characteristics
    • 2-Macroglobulin, a multifunctional binding protein with targeting characteristics. FASEB J. 6, 3345-3353.
    • (1992) FASEB J. , vol.6 , pp. 3345-3353
    • Borth, W.1
  • 5
    • 0026756887 scopus 로고
    • Methodological variables in the assessment of beta amyloid neurotoxicity
    • Busciglio J., Lorenzo A., and Yankner B. A. (1992) Methodological variables in the assessment of beta amyloid neurotoxicity. Neurobiol. Aging 13, 609-612.
    • (1992) Neurobiol. Aging , vol.13 , pp. 609-612
    • Busciglio, J.1    Lorenzo, A.2    Yankner, B.A.3
  • 6
    • 0026586383 scopus 로고
    • Synthesis and secretion of alpha-2-macroglobulin by human glioma established cell lines
    • Businaro R., Fabrizi C., Fumagalli L., and Lauro G. M. (1992) Synthesis and secretion of alpha-2-macroglobulin by human glioma established cell lines. Exp. Brain Res. 88, 213-218.
    • (1992) Exp. Brain Res. , vol.88 , pp. 213-218
    • Businaro, R.1    Fabrizi, C.2    Fumagalli, L.3    Lauro, G.M.4
  • 7
    • 0025737966 scopus 로고
    • Non-competitive antagonists of N-methyl-D-aspartate prevent spontaneous neuronal death in primary cultures of embryonic rat cortex
    • Drian M.-J., Kamenka J.-M., Pirat J.-L., and Privat A. (1991) Non-competitive antagonists of N-methyl-D-aspartate prevent spontaneous neuronal death in primary cultures of embryonic rat cortex. J. Neurosci. Res. 29, 133-138.
    • (1991) J. Neurosci. Res. , vol.29 , pp. 133-138
    • Drian, M.-J.1    Kamenka, J.-M.2    Pirat, J.-L.3    Privat, A.4
  • 10
    • 0028986858 scopus 로고
    • Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation
    • Eriksson S., Janciauskiene S., and Lannfelt L. (1995) Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation. Proc. Natl. Acad. Sci. USA 92, 2313-2317.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2313-2317
    • Eriksson, S.1    Janciauskiene, S.2    Lannfelt, L.3
  • 11
    • 0026673537 scopus 로고
    • Effects of sulfate ions on Alzheimer β/A4 peptide assemblies: Implications for amyloid fibril-proteoglycan interactions
    • Fraser P. E., Nguyen J. T., Chin D. T., and Kirschner D. A. (1992) Effects of sulfate ions on Alzheimer β/A4 peptide assemblies: implications for amyloid fibril-proteoglycan interactions. J. Neurochem. 59, 1531-1540.
    • (1992) J. Neurochem. , vol.59 , pp. 1531-1540
    • Fraser, P.E.1    Nguyen, J.T.2    Chin, D.T.3    Kirschner, D.A.4
  • 12
    • 0025881467 scopus 로고
    • Alpha-2-macroglobulin synthesis in interleukin 6-stimulated human neuronal (SH-SY5Y neuroblastoma) cells. Potential significance for the processing of Alzheimer beta-amyloid precursor protein
    • Ganter U., Strauss S., Jonas U., Weidemann A., Beyreuther K., Volk B., Berger M., and Bauer J. (1991) Alpha-2-macroglobulin synthesis in interleukin 6-stimulated human neuronal (SH-SY5Y neuroblastoma) cells. Potential significance for the processing of Alzheimer beta-amyloid precursor protein. FEBS Lett. 282, 127-131.
    • (1991) FEBS Lett. , vol.282 , pp. 127-131
    • Ganter, U.1    Strauss, S.2    Jonas, U.3    Weidemann, A.4    Beyreuther, K.5    Volk, B.6    Berger, M.7    Bauer, J.8
  • 14
    • 0028181690 scopus 로고
    • Expression of the alpha-2-macroglobulin-encoding gene in rat brain and cultured astrocytes
    • Higuchi M., Ito T., Imai Y., Iwaki T., Hattori M., Kohsaka S., Niho Y., and Sakaki Y. (1994) Expression of the alpha-2-macroglobulin-encoding gene in rat brain and cultured astrocytes. Gene 142, 155-162.
    • (1994) Gene , vol.142 , pp. 155-162
    • Higuchi, M.1    Ito, T.2    Imai, Y.3    Iwaki, T.4    Hattori, M.5    Kohsaka, S.6    Niho, Y.7    Sakaki, Y.8
  • 15
    • 0030597167 scopus 로고    scopus 로고
    • Neurite-promoting effect of alpha 2-macroglobulin in rat cerebral cortex is mainly associated with alpha 2-macroglobulin receptor
    • Ishii M., Osada T., Gliemann J., and Ikai A. (1996) Neurite-promoting effect of alpha 2-macroglobulin in rat cerebral cortex is mainly associated with alpha 2-macroglobulin receptor. Brain Res. 737, 269-274.
    • (1996) Brain Res. , vol.737 , pp. 269-274
    • Ishii, M.1    Osada, T.2    Gliemann, J.3    Ikai, A.4
  • 17
    • 0023425365 scopus 로고
    • Synthetic peptides homologous to β protein from Alzheimer disease form amyloid-like fibrils in vitro
    • Kirschner D. J., Inoye H., Duffy L. K., Sinclair A., Lind M., and Selkoe D. J. (1987) Synthetic peptides homologous to β protein from Alzheimer disease form amyloid-like fibrils in vitro. Proc. Natl. Acad. Sci. USA 84, 6953-6987.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 6953-6987
    • Kirschner, D.J.1    Inoye, H.2    Duffy, L.K.3    Sinclair, A.4    Lind, M.5    Selkoe, D.J.6
  • 18
    • 0026778656 scopus 로고
    • Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/β protein
    • Knauer M. F., Sorechan B., Burdick D., Kosmoski J., and Glabe C. G. (1992) Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/β protein. Proc. Natl. Acad. Sci. USA 89, 7437-7441.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7437-7441
    • Knauer, M.F.1    Sorechan, B.2    Burdick, D.3    Kosmoski, J.4    Glabe, C.G.5
  • 19
    • 0023035157 scopus 로고
    • Alpha-2-macroglobulin gene expression during rat development studied by in situ hybridization
    • Kodelja V., Heisig M., Northemann W., Heinrich P. C., and Zimmermann W. (1986) Alpha-2-macroglobulin gene expression during rat development studied by in situ hybridization. EMBO J. 5, 3151-3156.
    • (1986) EMBO J. , vol.5 , pp. 3151-3156
    • Kodelja, V.1    Heisig, M.2    Northemann, W.3    Heinrich, P.C.4    Zimmermann, W.5
  • 20
    • 0028180385 scopus 로고
    • Expression of alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells
    • Lopes M. B., Bogaev C. A., Gonias S. L., and Vandenberg S. R. (1993) Expression of alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells. FEBS Lett. 338, 301-305.
    • (1993) FEBS Lett. , vol.338 , pp. 301-305
    • Lopes, M.B.1    Bogaev, C.A.2    Gonias, S.L.3    Vandenberg, S.R.4
  • 21
    • 0028173205 scopus 로고
    • Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments
    • Ma J., Yee A., Brewer H. B. Jr., Das S., and Potter H. (1994) Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments. Nature 372, 92-94.
    • (1994) Nature , vol.372 , pp. 92-94
    • Ma, J.1    Yee, A.2    Brewer Jr., H.B.3    Das, S.4    Potter, H.5
  • 22
    • 0000448998 scopus 로고    scopus 로고
    • Alzheimer Aβ neurotoxicity: Promotion by antichymotrypsin, ApoE4; inhibition by Aβ-related peptides
    • Ma J., Brewer B. H. Jr., and Potter H. (1996) Alzheimer Aβ neurotoxicity: promotion by antichymotrypsin, ApoE4; inhibition by Aβ-related peptides. Neurobiol. Aging 17, 773-780.
    • (1996) Neurobiol. Aging , vol.17 , pp. 773-780
    • Ma, J.1    Brewer Jr., B.H.2    Potter, H.3
  • 23
    • 0027297138 scopus 로고
    • Calcium-destabilizing and neurodegenerative effects of aggregated β-amyloid peptide are attenuated by basic FGF
    • Mattson M. P., Tomaselli K. J., and Rydel R. E. (1993a) Calcium-destabilizing and neurodegenerative effects of aggregated β-amyloid peptide are attenuated by basic FGF. Brain Res. 621, 35-49.
    • (1993) Brain Res. , vol.621 , pp. 35-49
    • Mattson, M.P.1    Tomaselli, K.J.2    Rydel, R.E.3
  • 24
    • 0027367765 scopus 로고
    • β-Amyloid precursor protein metabolites and loss of neuronal calcium homeostasis in Alzheimer's disease
    • Mattson M. P., Barger S. W., Cheng B., Lieberburg I., Smith-Swintosky V. L., and Rydel R. E. (1993b) β-Amyloid precursor protein metabolites and loss of neuronal calcium homeostasis in Alzheimer's disease. Trends Neurosci. 16, 409-415.
    • (1993) Trends Neurosci. , vol.16 , pp. 409-415
    • Mattson, M.P.1    Barger, S.W.2    Cheng, B.3    Lieberburg, I.4    Smith-Swintosky, V.L.5    Rydel, R.E.6
  • 25
    • 0025196651 scopus 로고
    • Alpha 2-macroglobulin is an astroglia-derived neurite-promoting factor for cultured neurons from rat central nervous system
    • Mori T., Iijima N., Kitabatake K., and Kohsaka S. (1990) Alpha 2-macroglobulin is an astroglia-derived neurite-promoting factor for cultured neurons from rat central nervous system. Brain Res. 527, 55-61.
    • (1990) Brain Res. , vol.527 , pp. 55-61
    • Mori, T.1    Iijima, N.2    Kitabatake, K.3    Kohsaka, S.4
  • 26
    • 0024509805 scopus 로고
    • Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T
    • Naiki H., Higuchi K., Hosokawa M., and Takeda T. (1989) Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T. Anal. Biochem. 177, 244-249.
    • (1989) Anal. Biochem. , vol.177 , pp. 244-249
    • Naiki, H.1    Higuchi, K.2    Hosokawa, M.3    Takeda, T.4
  • 27
    • 0025992417 scopus 로고
    • In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity
    • Pike C. J., Walencewicz A. J., Glabe C. G., and Cotman C. W. (1991) In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563, 311-314.
    • (1991) Brain Res. , vol.563 , pp. 311-314
    • Pike, C.J.1    Walencewicz, A.J.2    Glabe, C.G.3    Cotman, C.W.4
  • 28
    • 0027374047 scopus 로고
    • Apolipoprotein e in sporadic Alzheimer's disease: Allelic variation and receptor interactions
    • Rebeck G. W., Reiter J. S., Strickland D. K., and Hyman B. T. (1993) Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron 11, 575-580.
    • (1993) Neuron , vol.11 , pp. 575-580
    • Rebeck, G.W.1    Reiter, J.S.2    Strickland, D.K.3    Hyman, B.T.4
  • 29
    • 0027936838 scopus 로고
    • Apolipoprotein e affects the rate of Alzheimer disease expression: β-amyloid burden is a secondary consequence dependent on Apoe genotype and duration of disease
    • Roses A. D. (1994) Apolipoprotein E affects the rate of Alzheimer disease expression: β-amyloid burden is a secondary consequence dependent on ApoE genotype and duration of disease. J. Neuropathol. Exp. Neurol. 53, 429-437.
    • (1994) J. Neuropathol. Exp. Neurol. , vol.53 , pp. 429-437
    • Roses, A.D.1
  • 31
    • 0028123071 scopus 로고
    • Alzheimer's disease: A central role for amyloid
    • Selkoe D. J. (1994) Alzheimer's disease: a central role for amyloid. J. Neuropathol. Exp. Neurol. 53, 438-447.
    • (1994) J. Neuropathol. Exp. Neurol. , vol.53 , pp. 438-447
    • Selkoe, D.J.1
  • 33
    • 0026553710 scopus 로고
    • Detection of interleukin-6 and α2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients
    • Strauss S., Bauer J., Ganter U., Jona S., Berger M., and Volk B. (1992) Detection of interleukin-6 and α2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients. Lab. Invest. 66, 223-230.
    • (1992) Lab. Invest. , vol.66 , pp. 223-230
    • Strauss, S.1    Bauer, J.2    Ganter, U.3    Jona, S.4    Berger, M.5    Volk, B.6
  • 34
    • 0027263617 scopus 로고
    • Immunohistochemical study of alpha 2 macroglobulin receptor in Alzheimer and control postmortem human brain
    • Tooyama I., Kawamata T., Akiyama H., Moestrup S. K., Gliemann J., and McGeer P. (1993) Immunohistochemical study of alpha 2 macroglobulin receptor in Alzheimer and control postmortem human brain. Mol. Chem. Neuropathol. 18, 153-160.
    • (1993) Mol. Chem. Neuropathol. , vol.18 , pp. 153-160
    • Tooyama, I.1    Kawamata, T.2    Akiyama, H.3    Moestrup, S.K.4    Gliemann, J.5    McGeer, P.6
  • 35
    • 0027160249 scopus 로고
    • α2-Macroglobulin expression in neuritic-type plaques in patients with Alzheimer's disease
    • van Gool D., De Strooper B., van Leuven F., Triau E., and Dom R. (1993) α2-Macroglobulin expression in neuritic-type plaques in patients with Alzheimer's disease. Neurobiol. Aging 14, 233-237.
    • (1993) Neurobiol. Aging , vol.14 , pp. 233-237
    • Van Gool, D.1    De Strooper, B.2    Van Leuven, F.3    Triau, E.4    Dom, R.5
  • 36
    • 0030918418 scopus 로고    scopus 로고
    • Aggregation state-dependent activation of the classical complement pathway by the amyloid β peptide
    • Webster S., Bradt B., Rogers J., and Cooper N. (1997) Aggregation state-dependent activation of the classical complement pathway by the amyloid β peptide. J. Neurochem. 69, 388-398.
    • (1997) J. Neurochem. , vol.69 , pp. 388-398
    • Webster, S.1    Bradt, B.2    Rogers, J.3    Cooper, N.4
  • 37
    • 0027444955 scopus 로고
    • Cerebrospinal fluid inhibits Alzheimer beta-amyloid fibril formation in vitro
    • Wisniewski T., Castano E., Ghiso J., and Frangione B. (1993) Cerebrospinal fluid inhibits Alzheimer beta-amyloid fibril formation in vitro. Ann. Neurol. 34, 631-633.
    • (1993) Ann. Neurol. , vol.34 , pp. 631-633
    • Wisniewski, T.1    Castano, E.2    Ghiso, J.3    Frangione, B.4
  • 38
    • 0027970307 scopus 로고
    • Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro
    • Wisniewski T., Castano E., Golabek A., Vogel T., and Frangione B. (1994) Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. Am. J. Pathol. 145, 1030-1035.
    • (1994) Am. J. Pathol. , vol.145 , pp. 1030-1035
    • Wisniewski, T.1    Castano, E.2    Golabek, A.3    Vogel, T.4    Frangione, B.5
  • 39
    • 0031013110 scopus 로고    scopus 로고
    • Characterization ot the binding of amyloid-β peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma
    • Yang D.-S., Smith J. D., Zhou Z., Gandy S. E., and Martins R. N. (1997) Characterization ot the binding of amyloid-β peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma. J. Neurochem. 68, 721-725.
    • (1997) J. Neurochem. , vol.68 , pp. 721-725
    • Yang, D.-S.1    Smith, J.D.2    Zhou, Z.3    Gandy, S.E.4    Martins, R.N.5
  • 40
    • 0024990330 scopus 로고
    • Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides
    • Yankner B. A., Duffy L. K., and Kirschner D. A. (1990) Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science 250, 279-282.
    • (1990) Science , vol.250 , pp. 279-282
    • Yankner, B.A.1    Duffy, L.K.2    Kirschner, D.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.