Somatic evolution in the immune system: The need for germinal centers for efficient affinity maturation

Journal of Theoretical Biology

Volumn 186, Issue 2, 1997, Pages 159-171

  Pierre, Darren M ^a   Goldman, Daniel ^b   Bar Yam, Yaneer ^b   Perelson, Alan S ^c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BOSTON UNIVERSITY   (United States)

^c LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTIGEN;

ANTIBODY AFFINITY; ARTICLE; CELL MATURATION; CELL PROLIFERATION; EVOLUTION; GERMINAL CENTER; HUMORAL IMMUNITY; LYMPHOID TISSUE; MODEL; PRIORITY JOURNAL; STOCHASTIC MODEL;

EID: 0031582380     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.1996.0350     Document Type: Article

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